McDougall on Market Potential of Personalized Medicine

T
The Ohio State University Wexner Medical CenterThe Ohio State University Wexner Medical Center
October 7th, 2011,[object Object],PwC Health Industries Advisory,[object Object],Draft,[object Object],Ohio State – 4th Annual Personalized Health Care National Conference,[object Object],Gerry McDougall,[object Object],Partner, U.S. Personalized Medicine & Health Sciences Leader,[object Object],Private and Confidential,[object Object]
PwC and our Personalized Medicine Practice,[object Object],  – ,[object Object],Established in July 1998 with the merger of Price Waterhouse and Coopers & Lybrand, PwC is the world’s largest professional services firm. ,[object Object],Globally, PwC’s revenue is over 30 billion dollars, of which close to 10 billion is consultancy.,[object Object],PwC provides a full range of business services, which include audit, accounting and tax advice; management, health care, information technology and human resource consulting; and financial advisory services including mergers & acquisitions and project finance.,[object Object],PricewaterhouseCoopers (PwC) is a global firm that draws upon the talents of more than 165,000 people in 150 countries.,[object Object],6/7/2011,[object Object],2,[object Object],PricewaterhouseCoopers LLP,[object Object]
PwC and our Personalized Medicine Practice,[object Object],  – ,[object Object],PwC's Healthcare Strategy is predicated on our ability to understand and help clients respond to key trends and to serve all sectors on the healthcare continuum,[object Object],10/7/2011,[object Object],3,[object Object],PricewaterhouseCoopers LLP,[object Object]
PwC and our Personalized Medicine Practice,[object Object],  – ,[object Object],PwC’s Definition:,[object Object],A holistic, individualized model of care that examines each individual’s unique makeup and designs appropriate strategies for maintaining wellness and treating illness.,[object Object],“The application of genomic and molecular data to better target the delivery of healthcare, facilitate the discovery and clinical testing of new products, and help determines a person’s predisposition to a particular disease or condition”,[object Object],(Senate bill sponsored by Senator Obama, 2007),[object Object],“A form of medicine that uses information about a person’s genes, proteins, and environment to prevent, diagnose, and treat disease”,[object Object],(US National Cancer Institute),[object Object],Personalized Medicine has many different definitions, and is broader than just molecular genomics,[object Object],PricewaterhouseCoopers LLP,[object Object],“The right treatment for the right person at the right time”,[object Object],10/7/2011,[object Object],4,[object Object]
PwC and our Personalized Medicine Practice,[object Object],  – ,[object Object],[object Object]
Key PwC efforts included:
Feasibility study and assessment
Affiliation agreements with academic and clinical partners
Business and financial planning
Strategic, operational, facilities planning
Overall operational implementation
Board development	PwC has been and continues to be involved in many TGen initiatives -  ,[object Object],TGen: Translational Genomics Research Institute: Development of a Research Institute, creation of a partnership,[object Object],10/7/2011,[object Object],5,[object Object],PricewaterhouseCoopers LLP,[object Object]
PwC and our Personalized Medicine Practice,[object Object],  – ,[object Object],PwC was the subject of an in-depth news article detailing its work with Luxembourg, partnering them with TGen to bring an integrated Biobank Center to Luxembourg,[object Object],PwC was engaged by the government of Luxembourg to assist them in diversifying their economy into the biosciences.  Partner Gerry McDougall was interviewed by the news agency about PwC’s’ leadership of this initiative - Highlights include:,[object Object],[object Object]
Luxembourg will complement what has been done in Europe by focusing initially on molecular diagnostics, and becoming a center of excellence around molecular diagnostics, in order to enable the early detection of diseases. Their aim is to not compete in established areas already, but to create a niche where they can take advantage of their geographic location.
PwC  goal with Luxembourg was to deliver knowledge transfer over the next three to five years, so that Luxembourg has the world-class sophistication to do the research —  proteomics and  systems biology.  PwC helped facilitate the training of Luxembourg scientists in the US and then re-establish themselves back in Luxembourg once the infrastructure is in place.
Luxembourg aimed to develop its center of excellence’ for bioscience by establishing a trans-Atlantic series of collaborations with three US-based institutions:  The Partnership for Personalized Medicine, the Institute for Systems Biology, and TGen.
PwC was the initial facilitator of these partnerships which drove over $250M into these US research organizations, and developed the plans for each of the new ventures. 10/7/2011,[object Object],6,[object Object],PricewaterhouseCoopers LLP,[object Object]
PwC and our Personalized Medicine Practice,[object Object],  – ,[object Object],The PricewaterhouseCoopers (PwC) Health Research Institute developed this report. It identifies and discusses significant trends reshaping health systems around the world, specifically the creation of a new, more efficient primary health system --  one that is patient centered and takes into account the evolving power of individuals. ,[object Object],To complete this report, PwC:,[object Object],[object Object]
 Conducted over 200 in-depth interviews globally (55 in the US) of top executives in government, hospital systems, insurance companies, physician groups, pharma and life science companies and technology firms in 25+ countries.
Surveyed 3,500 consumers (500 per country) in over 20+ countries including the UK, Germany, the Netherlands, Norway, the US, Canada, and Australia.HealthCast report: The Customization of Diagnosis, Care and Cure,[object Object],Through International Project Work and Global Research,  we have Developed a Deep Knowledge Base Regarding International InitiativesOne example – the development of our HealthCast 2010 report:,[object Object],PricewaterhouseCoopers LLP,[object Object],10/7/2011,[object Object],7,[object Object]
The Personalized Medicine Market,[object Object],  – ,[object Object],2008,[object Object],Total Market: $210-215bn,[object Object],2015,[object Object],Total Market: $344-452bn,[object Object],Nutrition & Wellness ,[object Object],Total: $185bn ,[object Object],Complementary & Alternative Medicine:$35bn,[object Object],Health Clubs & Spa:$35bn,[object Object],Nutrition & Wellness ,[object Object],Total: $292bn ,[object Object],CAGR,[object Object],’08-’15,[object Object],Complementary & Alternative Medicine:$41bn,[object Object],Health Clubs & Spa:$61bn,[object Object],Nutrition/ Organic care:$112bn,[object Object],Medical Retail:,[object Object],$3bn,[object Object],Personalized Medical Care ,[object Object],Total: $4-9bn ,[object Object],RPM/ Telemedicine:$0-5bn,[object Object],EMR: ,[object Object],$2bn,[object Object],Nutrition/ Organic care:$181bn,[object Object],Nutrition & Wellness,[object Object],7%,[object Object],CORE P4 ,[object Object],Total: $21bn ,[object Object],Medical Retail:,[object Object],$10bn,[object Object],The Market Potential is Huge,[object Object],PricewaterhouseCoopers LLP,[object Object],DM: ,[object Object],$2bn,[object Object],7%,[object Object],Personalized Medical Care ,[object Object],Total: $9-118bn ,[object Object],Nutrition/Organic,[object Object],Esoteric Lab Services:$5bn,[object Object],Esoteric  Test Sales:$4bn ,[object Object],2%,[object Object],Comp & Alt Medic.,[object Object],EMR: ,[object Object],$6bn,[object Object],RPM/ Telemedicine:$0-109bn,[object Object],22%,[object Object],Medical Retail,[object Object],Health Clubs & Spa,[object Object],10%,[object Object],DM: ,[object Object],$3bn,[object Object],CORE P4 ,[object Object],Total: $42bn ,[object Object],Targeted Therapeutics:,[object Object],$12bn,[object Object],Personalized Medical Care,[object Object],44%,[object Object],RPM/Telemedicine,[object Object],23%-92%,[object Object],Esoteric Lab Services:$11bn,[object Object],Esoteric  Test Sales:$10bn ,[object Object],EMR,[object Object],15%,[object Object],Molecular Diagnostics: $3bn,[object Object],Disease Mgmt,[object Object],6%,[object Object],10%,[object Object],CORE P4,[object Object],Targeted Therapeutics:,[object Object],$21bn,[object Object],Esoteric Lab Serv.,[object Object],10%,[object Object],Esoteric Test Sales,[object Object],13%,[object Object],Targ. Therapeutics,[object Object],9%,[object Object],Note: Totals may differ due to rounding,[object Object],Molecular Diagnostics: $7bn,[object Object],Figures Not Drawn to Scale,[object Object],1 Reflects upper range of RPM/Telemedicine,[object Object],“One of the innovation areas with the highest impact will be the whole field of early and correct diagnoses.” ,[object Object],- Mars di Bartolomeo, Luxembourg Minister of Health,[object Object],PwC Health Industries Advisory • ,[object Object],10/7/2011,[object Object],8,[object Object]
A New Emerging Paradigm,[object Object],PricewaterhouseCoopers LLP,[object Object],Sick,[object Object],Healthy,[object Object],Vulnerable,[object Object],Affected,[object Object],The Personalized Medicine Market,[object Object],  – ,[object Object],Expanded view of Health & Wellness,[object Object],Traditional view of Health & Wellness,[object Object],Treatment,[object Object],Delivery,[object Object],Consumer,[object Object],Problem,[object Object],Diagnosis,[object Object],Treatment Plan,[object Object],Treatment,[object Object],Delivery,[object Object],Patient,[object Object],Problem,[object Object],Diagnosis,[object Object],Treatment Plan,[object Object],Resort/Spa,[object Object],Preventative,[object Object],Hospital,[object Object],Surgery,[object Object],Patient,[object Object],Diagnosis,[object Object],Home/Gym,[object Object],Emotional,[object Object],(Social / Spiritual),[object Object],Preventative ,[object Object],& Chronic,[object Object],Group/,[object Object],Community,[object Object],Physician,[object Object],Diagnosis,[object Object],Chronic,[object Object],Physical,[object Object],Discomfort,[object Object],Physician,[object Object],Physician/nurse,[object Object],Clinic,[object Object],Surgery,[object Object],Mental,[object Object],Physician office/Clinic,[object Object],Nurse,[object Object],Diagnosis,[object Object],Chronic & Clinical,[object Object],Preventative,[object Object],Physical,[object Object],ASC/,[object Object],Outpatient center,[object Object],Alternative,[object Object],Diagnosis,[object Object],Physician office,[object Object],Exam,[object Object],Clinical,[object Object],Preventative,[object Object],Hospital,[object Object],CDC Definition of Wellness – covers all phases of patient well being,[object Object],10/7/2011,[object Object],9,[object Object]
The Broad Health and Wellness Perspective of a Large Global Consumer Products Company Demonstrates the Wealth of Potential Strategic Partners,[object Object],10/7/2011,[object Object],10,[object Object],PricewaterhouseCoopers LLP,[object Object],Key players:Molecular Diagnostics,[object Object],The Personalized Medicine Market,[object Object],  – ,[object Object],Sports Nutrition ,[object Object],Programs,[object Object],Digital Coaching Programs,[object Object],Health,[object Object],E-Games,[object Object],Health-Based ,[object Object],Social Media,[object Object],Personalized,[object Object],Fitness,[object Object],Wellness Mobile Applications,[object Object],Weight Management Centered Media,[object Object],Exergame Equipment,[object Object],and Fitness Centers,[object Object],Personal,[object Object],Monitoring,[object Object],Sports,[object Object],Entertainment,[object Object],Wellness Market,[object Object],Technology,[object Object],Sports Nutrition Programs,[object Object],Health Data ,[object Object],Aggregation,[object Object],Nutrition / ,[object Object],Consumer Goods,[object Object],Healthcare,[object Object],Employer Initiatives ,[object Object],to Decrease Health Costs ,[object Object],Personalized ,[object Object],Skincare & Cosmetics,[object Object],Personalized Medicine / Genetic Testing,[object Object],Functional Foods,[object Object],and Drinks,[object Object],Community Based ,[object Object],Awareness Initiatives,[object Object],Personalized Health ,[object Object],and Lifestyle Coaching,[object Object],Government Initiatives to ,[object Object],Decrease Health Costs,[object Object],Activity Management,[object Object],and Wellness Programs,[object Object],Home Health Monitoring,[object Object]
  – ,[object Object],Social Media puts pressure on scientists, politicians and funders to alter research priorities despite absence of credible scientific evidence,[object Object],[object Object]
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McDougall on Market Potential of Personalized Medicine

Hinweis der Redaktion

  1. Welcome / Introduction - Comment on the extraordinary energy / enthusiasm re: PM- Reinforce the importance for payers of better understanding how to manage the advancements in genomics- Note that cost / reimbursement issues are of paramount importance
  2. Could Personalized Medicine dramatically change this picture?- PwC defines personalized medicine as a holistic, individualized model of care that examines each individual’s unique makeup and designs appropriate strategies for maintaining wellness and treating illness.- Personalized medicine is often defined as “the right treatment for the right person at the right time.”
  3. Market sizing- Scientific advancement and a culture of wellness are converging to drive a huge and booming market for personalized medicine: $232 billion market, growing 11% annually to $452 billion by 2015
  4. PM is a disruptive innovation- It will change the role of traditional healthcare organizations and challenge their business models - Growing number of companies entering the space, even from outside health industry- Numerous challenges and risks in a rapidly expanding industry that is heavily regulated- Continuing evolution of the science of medicine
  5. Diagnostics: the key- Huge growth- 1,800 tests now available- 5-10 per week coming online- Payers need to assess their effectiveness / impact on disease prevention / treatment
  6. Payer landscape- Let’s take a high-level view of health landscape from the payer’s point of view- Talk through the ‘model’ PwC is building. It’s characterized by several continua:- Financial reimbursement (fee-for-service … full capitation)- Health management (preventative … episodic)- Care delivery (wellness … chronic)- Discuss the reimbursement implications and value proposition for payers- Investments in the preventive end of the spectrum can reduce costs at the episodic end of the spectrum- Note that PwC is using claims data and actuarial analysis to build a PM business model for payers