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Notes on Philippine Medically Important Protozoans Part 3 (Malarian spp.)
                                                                  Meccar Moniem Elino, BSBio IV , Davao Doctors College
                                                                  Instructor: Mrs. Chalee Sienes-Reyes, RMT, MSMT, Ph.D
                            Reference: Philippine textbook of Medical Parasitology 2nd ed.(2004) UP. Edited by Vicente Y. Belizario, Jr. and Winifreda U. de Leon



                                                                                                                                                                            No. of
                RBC Stage        Size of RBC         Dots               Trophozoite                  Schizont           Disease           Cytoplasm           Pigment                   Gametocyte
                                                                                                                                                                           Merozoite

                                                                                                showing the large
                                                                   Red blood cells infected         number of
                                                                                                                        Benign
                                                                     by P. vivax are often     merozoites typical
                                                                                                                       Tertian;       Irregular, ameboid       Golden
                                                                 larger than uninfected red    of this species (16-                                                          12-24
                                                                                                                      merozoites      in trophozoite, has      brown,
   P.vivax       Young            enlarge         Schauffner's            blood cells.                  24).                                                               Average is    rounded
                                                                                                                       released            spread out          incons-
                                                                   They are approximately      Also note the larger                                                           16
                                                                                                                       every 48           appearance           picuous
                                                                    1.5 times the size of a    size compared to a
                                                                                                                          hrs
                                                                          normal cell.          normal red blood
                                                                                                        cell.
                                                                                                                                                                              6-12
                                                                                                                                                                           Average is
                                                                                                    containing         Quartan;       Rounded, compact
                                                                                                                                                                Dark            8,
                                                                                                 merozoites (6 to     merozoites       trophozoite with
                                                                                                                                                               brown,       “rosette”
P. malariae      Mature           normal           Zeimann's                                    12) giving a coarse    released       dense cytoplasm/                                   rounded
                                                                                                                                                                cons-       schizonts
                                                                                                     granular         every 36-      band form troph are
                                                                                                                                                               picuous         are
                                                                                                   appearance.          48 hrs            rarely seen
                                                                                                                                                                           sometimes
                                                                                                                                                                              seen

                                                                                                                                                                              6-12
                                                                                                                        Benign                                             Average is
                                                                                                                                      Rounded, compact
                                                                                                                       Tertian;                                 Dark            8,
                                                                                                                                       trophozoite with
                                                                                                                      merozoites                               brown,       “rosette”
  P. ovale       Young            enlarge         Schauffner's                                                                        dense cytoplasm/                                   rounded
                                                                                                                       released                                 cons-       schizonts
                                                                                                                                     band form troph are
                                                                                                                       every 48                                picuous         are
                                                                                                                                          rarely seen
                                                                                                                          hrs                                              sometimes
                                                                                                                                                                              seen


                                                                   Early trophozoites have
                                                                                                                      Malignant
                                                                  the characteristic signet                                                                      Black
                                                                                               The gametocytes of      Tertian;        Young rings are
                                                                          ring shape.                                                                        coarse and       6-32
                              normal/multiple                                                   P. falciparum have    merozoites        small, delicate,                                crescent or
P. falciparum   all stage                          Maurer's           Also, unique to P.                                                                         cons-     Average is
                                 infection                                                         a crescent or       released       often with double                                   banana
                                                                 falciparum is the presence                                                                   picuous in     20-24
                                                                                                  banana shape.        every 72        chromatin mass
                                                                  of multiple trophozoites                                                                   gametocyte
                                                                                                                          hrs
                                                                          in one cell.

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PROTOZOAN part 3

  • 1. Notes on Philippine Medically Important Protozoans Part 3 (Malarian spp.) Meccar Moniem Elino, BSBio IV , Davao Doctors College Instructor: Mrs. Chalee Sienes-Reyes, RMT, MSMT, Ph.D Reference: Philippine textbook of Medical Parasitology 2nd ed.(2004) UP. Edited by Vicente Y. Belizario, Jr. and Winifreda U. de Leon No. of RBC Stage Size of RBC Dots Trophozoite Schizont Disease Cytoplasm Pigment Gametocyte Merozoite showing the large Red blood cells infected number of Benign by P. vivax are often merozoites typical Tertian; Irregular, ameboid Golden larger than uninfected red of this species (16- 12-24 merozoites in trophozoite, has brown, P.vivax Young enlarge Schauffner's blood cells. 24). Average is rounded released spread out incons- They are approximately Also note the larger 16 every 48 appearance picuous 1.5 times the size of a size compared to a hrs normal cell. normal red blood cell. 6-12 Average is containing Quartan; Rounded, compact Dark 8, merozoites (6 to merozoites trophozoite with brown, “rosette” P. malariae Mature normal Zeimann's 12) giving a coarse released dense cytoplasm/ rounded cons- schizonts granular every 36- band form troph are picuous are appearance. 48 hrs rarely seen sometimes seen 6-12 Benign Average is Rounded, compact Tertian; Dark 8, trophozoite with merozoites brown, “rosette” P. ovale Young enlarge Schauffner's dense cytoplasm/ rounded released cons- schizonts band form troph are every 48 picuous are rarely seen hrs sometimes seen Early trophozoites have Malignant the characteristic signet Black The gametocytes of Tertian; Young rings are ring shape. coarse and 6-32 normal/multiple P. falciparum have merozoites small, delicate, crescent or P. falciparum all stage Maurer's Also, unique to P. cons- Average is infection a crescent or released often with double banana falciparum is the presence picuous in 20-24 banana shape. every 72 chromatin mass of multiple trophozoites gametocyte hrs in one cell.