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HERPES ZOSTER -
SHINGLES
CHICKENPOX - VARICELLA
Disediakan
Oleh : Nassruto
DEFINISI
HERPES ZOSTER -
SHINGLES
• Infeksi kulit melibatkan & saraf dengan ledakan
inflamatori di dalam kulit bermula dari T3 – L3
Agen Penyebab
• Human (alpha) herpesvirus 3 (Virus Varicella Zoster –
V-Z Virus), a member of the Herpesvirus group
• Reactivation infection with the virus that causes
CHICKENPOX
• Attack to skin area supplied by sensory nerves
Insiden
• Semua golongan seluruh dunia
• Pesakit leukaemia, Hodgkin & limpoma
• Pesakit menerima rawatan kanser, kosteroid
• Belaku banyak pada orang dewasa - tua
• 10% pada kanak-kanak
• Pesakit HIV berisiko tinggi mendapat zoster
Reservoir
• Man
Mode of transmission
• Direct contact
• Droplet / airborne
• Respiratory tract
• Vesicle fluid
Incubation period
• 2-3 weeks
• Commonly 13- 17 days.
Period of
communicability
• 1 week
• 10-21 days – susceptible persons
Susceptibility and
resistance
• Universal among those not previously infected
• More severe in adults than of children
• Second attacks are rare
• Leukemia patient – suffer more severe, prolong or
fatal chickenpox.
Susceptibility and
resistance
• Cancer patients
• Steroid therapy
• Immuno-deficient patients
• Immunisuppressive therapy
Menifestasi Klinikal
• Kesakitan tulang belakang
• Bintik merah pada dada, leher, muka dan selaput
mukosa
• Sakit yang kuat atau rasa kebas
Komplikasi
• Parut
• Neuralgia
• Motor palsi
• Keratitis
Penyelidikan
• Calitan lesi
• Serologi
Rawatan
• Simptomatik
• Antiviral
• Steroid
• Vitamin E
Method of control
• Preventive measures
• control of patients, contact and the immediate
environment
Preventive measures
• Health education
• personal hygiene
• Avoid contaminating skin
• with infectious material
• Health personnel
• wear glove
Preventive measures
• Protect high risk individu
• Neonates
• Immuno-deficient patients
Control of patients,
contact and the
immediate environment
• Report - notification
• Isolation from;
• neonatal
• severe primary lesion
• drainage/ secretion
• newborn baby
• School children at least 5 days
• immunosuppressed patients
Control of patients,
contact and the
immediate environment
• Concurrent disinfection;
• Discharges from nose, throat, lesions
• Quarantine ; none
• Immunization of contacts:
• VZIG given within 96 hours
• Investigation of contacts and source of infection; of no
practical importance
Control of patients,
contact and the
immediate environment
• Specific treatment:
• zovirax
• Epidemic measures: none
• Disaster implications: outbreaks
• International measure: none
THANK YOU

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