SlideShare ist ein Scribd-Unternehmen logo
1 von 38
Downloaden Sie, um offline zu lesen
Primary Post
Partum
Haemorrhage
BY NANDINII RAMASENDERAN
Overview…
 Definition
 Causes :
 Uterine atony
 Retained placenta
 Genital tract trauma
 Coagulation disorders
 Risk Factors
 Investigations
 Emergency management
 Specific management
Introduction:
 Obstetric haemorrhage remains one of the major causes of
maternal death in both developed and developing countries.
 In the 2003–2005 report of the UK Confidential Enquiries into
Maternal Deaths, haemorrhage was the third highest direct cause
of maternal death (6.6 deaths/million maternities).
 Haemorrhage emerges as the major cause of severe maternal
morbidity in almost all ‘near miss’ audits in both developed and
developing countries
Source: RCOG, Prevention and management of post partum haemorrhage 1st
edition, 2009
Definition of PPH:
 Loss of 500 ml or more of blood from the genital
tract within 24hours of the birth of a baby.
 PPH can be minor (500–1000 ml) or major (more
than 1000 ml)
 Major could be divided to moderate (1000–2000
ml) or severe (more than 2000 ml).
Source: RCOG, Prevention and management of post partum haemorrhage 1st
edition, 2009
Causes of primary PPH ( 4Ts)
What are the risks of PPH?
Source: RCOG, Prevention and management of post partum haemorrhage 1st
edition, 2009)
Source: RCOG, Prevention and management of post partum haemorrhage 1st
edition, 2009)
1. Uterine Atony
Predisposing conditions:
2. Retained Placenta
3. Genital Tract Trauma
 Bleeding from or into genital tract due to trauma to uterus,
cervix, vagina & introitus.
 bleeding can be profuse
 Predisposing factors :
 perineal tear,
 episiotomies and ruptured vulval varicosities
 Macrosomic babies,
 Instrumental deliveries
 Uterine rupture
 Vaginal wall hematomas
4. Coagulation disorders
 Predisposing factors
 Amniotic fluid embolism
 Abruptio placenta
 Sepsis
 Massive blood loss and transfusion
 Severe PE
 Chorioamnionitis
 Idiopathic thrombocytopenia
Management
 Practical management of PPH may be considered as
having at least four components:
 communication with all relevant professionals;
 resuscitation;
 monitoring and investigation;
 measures to arrest the bleeding
Source: RCOG, Prevention and management of post partum haemorrhage 1st
edition, 2009)
1. Who should be informed when the woman
presents with PPH?
 Basic measures for MINOR PPH (blood loss 500–1000 ml, no clinical shock):
 Alert the midwife-in-charge.
 Alert first-line obstetric and anaesthetic staff trained in the management of
PPH.
 Full protocol for MAJOR PPH (blood loss more than 1000 ml and continuing to
bleed OR clinical shock):
 Call experienced midwife (in addition to midwife in charge).
 Call obstetric middle grade and alert consultant.
 Call anaesthetic middle grade and alert consultant.
 Alert consultant clinical haematologist on call.
 Alert blood transfusion laboratory.
 Call porters for delivery of specimens/blood.
 Alert one member of the team to record events, fluids, drugs and vital signs.
Source: RCOG, Prevention and management of post partum haemorrhage 1st
edition, 2009)
2. Resuscitation A , B , C
Clinical Presentation & Physiological Response to blood loss
Estimating blood loss
 Basic measures for MINOR PPH (blood loss 500–1000 ml, no clinical shock):
 Intravenous access (14-gauge cannula x 1).
 Commence crystalloid infusion.
 Full protocol for MAJOR PPH (blood loss > 1000 ml and continuing to bleed OR clinical shock):
 Assess airway. Assess breathing. Evaluate circulation
 Oxygen by mask at 10–15 litres/minute. Intravenous access (14-gauge cannula x 2, orange
cannulae).
 Position flat. Keep the woman warm using appropriate available measures.
 Transfuse blood as soon as possible.
 Until blood is available, infuse up to 3.5 litres of warmed crystalloid Hartmann’s solution (2 litres)
and/or colloid (1–2 litres) as rapidly as required.
 The best equipment available should be used to achieve RAPID WARMED infusion of fluids.
 Special blood filters should NOT be used, as they slow infusions.
 Recombinant factor VIIa therapy should be based on the results of coagulation.
Source: RCOG, Prevention and management of post partum haemorrhage 1st
edition, 2009)
Fluid therapy and blood product
Crystalloid : Up to 2 litres Hartmann’s solution
Colloid : Up to 1–2 litres colloid until blood arrives
Blood : Cross matched. If crossmatched blood is still unavailable, give
uncrossmatched group-specific blood OR give ‘O RhD negative’
blood
Fresh frozen plasma : 4 units for every 6 units of red cells or prothrombin
time/activated partial thromboplastin time > 1.5 x
normal (12–15 ml/kg or total 1 litres)
Platelets concentrates : if PLT count < 50 x 109
Cryoprecipitate : If fibrinogen < 1 g/l
Source: RCOG, Prevention and management of post partum haemorrhage 1st
edition, 2009)
2006 guideline from the British Committee for
Standards in Haematology:
 Main therapeutic goals of management of massive blood
loss is to maintain:
 haemoglobin > 8g/dl
 platelet count > 75 x 109/l
 prothrombin < 1.5 x mean control
 activated prothrombin times < 1.5 x mean control
 fibrinogen > 1.0 g/l
Source: RCOG, Prevention and management of post partum haemorrhage 1st
edition, 2009)
3. What investigations should be performed and how should
the woman be monitored?
Basic measures for MINOR PPH (blood loss 500–1000 ml, no clinical shock and bleeding ceasing):
 Consider venepuncture (20 ml) for:
 group and screen
 full blood count
 coagulation screen including fibrinogen
 pulse and blood pressure recording every 15 minutes.
Full Protocol for MAJOR PPH (blood loss greater than 1000ml and continuing to bleed OR clinical shock):
 Consider venepuncture (20 ml) for: crossmatch (4 units minimum)
 full blood count
 coagulation screen including fibrinogen
 renal and liver function for baseline.
Source: RCOG, Prevention and management of post partum haemorrhage 1st
edition, 2009)
4. Arrest the bleeding
 Causes for PPH may be considered to relate to one or more of ‘the four Ts’:
 tone (abnormalities of uterine contraction)
 tissue (retained products of conception)
 trauma (of the genital tract)
 thrombin (abnormalities of coagulation).
The most common cause of primary PPH is uterine atony. However, clinical
examination must be undertaken to exclude other or additional causes:
 retained products (placenta, membranes, clots)
 vaginal/cervical lacerations or haematoma
 ruptured uterus
 broad ligament haematoma
 extragenital bleeding (for example, subcapsular liver rupture)
 uterine inversion.
Source: RCOG, Prevention and management of post partum haemorrhage 1st
edition, 2009)
Specific Management
Uterine Atony
If fail……..
Aortic compresionAortic compresion
Bimanual
compression
Surgical Mx
B-Lynch Suture
Hemostatic
suturing technique
Tamponade Test
Genital Tract Trauma
Retained Placenta
Manual Removal of Placenta
Manual replacement
MRP
Algorithm of management
Management of uterine atony
IV Ergometrine (0.5mg x 2 doses
IM Syntometrine 1mL (0.5 Ergometrine & 5 IU oxytocin
Oxytocin (40 units in 500 mL NS at 40dpm
IM Carboprost 250mcg (repeat after 15 min up to max 5 doses)
Empty bladder
Uterine massage/ compression
IV access, fluids
Placenta delivered &
complete
Observe/ monitor
Continue oxytocin 6-12 hours
Then off and observe
Bleeding stops
Uterine Atony
Persistent bleeding
1) PGE-intrauterine, intramuscular, intravenous,
intrarectal
2) PGF-2α-IM Carboprost
(repeat after 15min up to max 5 doses)
Uterine/ ovarian/ internal iliac artery ligation
Uterine tamponade (b-lynch suture/ brace suture
Hysterectomy
Summary of management:

Weitere ähnliche Inhalte

Was ist angesagt? (20)

Preterm labour
Preterm labourPreterm labour
Preterm labour
 
post partum haemorrhage
post partum haemorrhagepost partum haemorrhage
post partum haemorrhage
 
Bleeding in early & late pregnancy
Bleeding in early  & late pregnancyBleeding in early  & late pregnancy
Bleeding in early & late pregnancy
 
Hyperemesis gravidarum
Hyperemesis gravidarumHyperemesis gravidarum
Hyperemesis gravidarum
 
Cardiac disease in pregnancy
Cardiac disease in pregnancyCardiac disease in pregnancy
Cardiac disease in pregnancy
 
Post term pregnancy
Post term pregnancyPost term pregnancy
Post term pregnancy
 
Oligohydramnios
OligohydramniosOligohydramnios
Oligohydramnios
 
Aph
AphAph
Aph
 
Abruptio placentae
Abruptio placentae Abruptio placentae
Abruptio placentae
 
Post term pregnancy
Post term pregnancyPost term pregnancy
Post term pregnancy
 
Prom
PromProm
Prom
 
Placenta praevia
Placenta praeviaPlacenta praevia
Placenta praevia
 
Rupture uterus
Rupture uterusRupture uterus
Rupture uterus
 
Abortion and post abortion care
Abortion and post abortion careAbortion and post abortion care
Abortion and post abortion care
 
Obstructed labour
Obstructed labourObstructed labour
Obstructed labour
 
Pph drill
Pph drillPph drill
Pph drill
 
Oligohydramnios
OligohydramniosOligohydramnios
Oligohydramnios
 
Pre-Eclampsia & Eclampsia
Pre-Eclampsia & EclampsiaPre-Eclampsia & Eclampsia
Pre-Eclampsia & Eclampsia
 
Prolonged labour
Prolonged labourProlonged labour
Prolonged labour
 
Uterine rupture
Uterine ruptureUterine rupture
Uterine rupture
 

Ähnlich wie Primary post partum haemorrhage

Medical management of Post Partum Haemorrhage
Medical management of Post Partum HaemorrhageMedical management of Post Partum Haemorrhage
Medical management of Post Partum HaemorrhageNandini Jahagirdar Joshi
 
Overview management of postpartum haemorrhage
Overview management of postpartum haemorrhageOverview management of postpartum haemorrhage
Overview management of postpartum haemorrhageAhmed Almumtin
 
Hemorragia post parto.pdf
Hemorragia post parto.pdfHemorragia post parto.pdf
Hemorragia post parto.pdffatimabarria
 
Hemorragia post parto.pdf
Hemorragia post parto.pdfHemorragia post parto.pdf
Hemorragia post parto.pdffatimabarria
 
Massive Postpartum haemorrhage
Massive Postpartum haemorrhageMassive Postpartum haemorrhage
Massive Postpartum haemorrhageAl Mamun
 
Massive Postpartum haemorrhage
Massive Postpartum haemorrhageMassive Postpartum haemorrhage
Massive Postpartum haemorrhageDrRokeyaBegum
 
Obstetric hemorrhage: anesthetic implications and management
Obstetric hemorrhage: anesthetic implications and managementObstetric hemorrhage: anesthetic implications and management
Obstetric hemorrhage: anesthetic implications and managementmarwa Mahrous
 
Hemorragia posparto acog oct 2017 (1)
Hemorragia posparto acog oct 2017 (1)Hemorragia posparto acog oct 2017 (1)
Hemorragia posparto acog oct 2017 (1)Mãrlon Galvis Cinho
 
Acog hemorragia posparto acog 2017
Acog hemorragia posparto acog 2017Acog hemorragia posparto acog 2017
Acog hemorragia posparto acog 2017Clinica Robles S.A.C
 
Postpartum haemorrhage
Postpartum haemorrhagePostpartum haemorrhage
Postpartum haemorrhageDr. Rubz
 
Postpartum haemorrhage
Postpartum haemorrhagePostpartum haemorrhage
Postpartum haemorrhageMohd Hanafi
 
Post Partum Hemorrhage in ED
Post Partum Hemorrhage in EDPost Partum Hemorrhage in ED
Post Partum Hemorrhage in EDRunal Shah
 
pph-150512151237-lva1-app6892.pptx
pph-150512151237-lva1-app6892.pptxpph-150512151237-lva1-app6892.pptx
pph-150512151237-lva1-app6892.pptxdimasfujiansyah1
 
Massive PPH
Massive PPH Massive PPH
Massive PPH shalu76
 

Ähnlich wie Primary post partum haemorrhage (20)

Medical management of Post Partum Haemorrhage
Medical management of Post Partum HaemorrhageMedical management of Post Partum Haemorrhage
Medical management of Post Partum Haemorrhage
 
PPH.pptx
PPH.pptxPPH.pptx
PPH.pptx
 
Post partum haemorrhage
Post partum haemorrhage Post partum haemorrhage
Post partum haemorrhage
 
Overview management of postpartum haemorrhage
Overview management of postpartum haemorrhageOverview management of postpartum haemorrhage
Overview management of postpartum haemorrhage
 
Hemorragia post parto.pdf
Hemorragia post parto.pdfHemorragia post parto.pdf
Hemorragia post parto.pdf
 
Hemorragia post parto.pdf
Hemorragia post parto.pdfHemorragia post parto.pdf
Hemorragia post parto.pdf
 
Pph workshop 1 (9 2013)
Pph workshop 1 (9 2013)Pph workshop 1 (9 2013)
Pph workshop 1 (9 2013)
 
Ob hemorrhage
Ob hemorrhageOb hemorrhage
Ob hemorrhage
 
Massive Postpartum haemorrhage
Massive Postpartum haemorrhageMassive Postpartum haemorrhage
Massive Postpartum haemorrhage
 
Massive Postpartum haemorrhage
Massive Postpartum haemorrhageMassive Postpartum haemorrhage
Massive Postpartum haemorrhage
 
Pph
PphPph
Pph
 
Obstetric hemorrhage: anesthetic implications and management
Obstetric hemorrhage: anesthetic implications and managementObstetric hemorrhage: anesthetic implications and management
Obstetric hemorrhage: anesthetic implications and management
 
Hemorragia posparto acog oct 2017 (1)
Hemorragia posparto acog oct 2017 (1)Hemorragia posparto acog oct 2017 (1)
Hemorragia posparto acog oct 2017 (1)
 
Acog hemorragia posparto acog 2017
Acog hemorragia posparto acog 2017Acog hemorragia posparto acog 2017
Acog hemorragia posparto acog 2017
 
Postpartum haemorrhage
Postpartum haemorrhagePostpartum haemorrhage
Postpartum haemorrhage
 
Postpartum haemorrhage
Postpartum haemorrhagePostpartum haemorrhage
Postpartum haemorrhage
 
Post Partum Hemorrhage in ED
Post Partum Hemorrhage in EDPost Partum Hemorrhage in ED
Post Partum Hemorrhage in ED
 
Postpartum Haemorrhage O&G
Postpartum Haemorrhage O&GPostpartum Haemorrhage O&G
Postpartum Haemorrhage O&G
 
pph-150512151237-lva1-app6892.pptx
pph-150512151237-lva1-app6892.pptxpph-150512151237-lva1-app6892.pptx
pph-150512151237-lva1-app6892.pptx
 
Massive PPH
Massive PPH Massive PPH
Massive PPH
 

Mehr von Nandinii Ramasenderan (20)

Hand infections
Hand infectionsHand infections
Hand infections
 
Eye & ent emergencies
Eye & ent emergenciesEye & ent emergencies
Eye & ent emergencies
 
Acute pancreatitis
Acute pancreatitisAcute pancreatitis
Acute pancreatitis
 
Organophosphate poisoning
Organophosphate poisoningOrganophosphate poisoning
Organophosphate poisoning
 
Houseofficer teaching-paeds:shock
Houseofficer teaching-paeds:shockHouseofficer teaching-paeds:shock
Houseofficer teaching-paeds:shock
 
Breastfeeding journals
Breastfeeding journalsBreastfeeding journals
Breastfeeding journals
 
Evidence based medicine nandinii080100332
Evidence based medicine nandinii080100332Evidence based medicine nandinii080100332
Evidence based medicine nandinii080100332
 
Chronic obstructive airway disease (coad)
Chronic obstructive airway disease (coad)Chronic obstructive airway disease (coad)
Chronic obstructive airway disease (coad)
 
Uterine inversion & cord prolapse
Uterine inversion & cord prolapseUterine inversion & cord prolapse
Uterine inversion & cord prolapse
 
Immunological diseases in pregnancy
Immunological diseases in pregnancyImmunological diseases in pregnancy
Immunological diseases in pregnancy
 
Physiological changes in pregnancy
Physiological changes in pregnancyPhysiological changes in pregnancy
Physiological changes in pregnancy
 
Renal physiology in pregnancy
Renal physiology in pregnancyRenal physiology in pregnancy
Renal physiology in pregnancy
 
Updated trigeminal neuralgia
Updated trigeminal neuralgiaUpdated trigeminal neuralgia
Updated trigeminal neuralgia
 
trigeminal neuralgia
trigeminal neuralgiatrigeminal neuralgia
trigeminal neuralgia
 
Acute epiglottitis
Acute epiglottitisAcute epiglottitis
Acute epiglottitis
 
Intestinal obstruction
Intestinal obstructionIntestinal obstruction
Intestinal obstruction
 
Ulcers & skin infections
Ulcers & skin infectionsUlcers & skin infections
Ulcers & skin infections
 
Congenital cataract
Congenital cataractCongenital cataract
Congenital cataract
 
Appendicitis
AppendicitisAppendicitis
Appendicitis
 
Pancreatitis
PancreatitisPancreatitis
Pancreatitis
 

Kürzlich hochgeladen

Giftedness: Understanding Everyday Neurobiology for Self-Knowledge
Giftedness: Understanding Everyday Neurobiology for Self-KnowledgeGiftedness: Understanding Everyday Neurobiology for Self-Knowledge
Giftedness: Understanding Everyday Neurobiology for Self-Knowledgeassessoriafabianodea
 
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic Analysis
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic AnalysisVarSeq 2.6.0: Advancing Pharmacogenomics and Genomic Analysis
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic AnalysisGolden Helix
 
The next social challenge to public health: the information environment.pptx
The next social challenge to public health:  the information environment.pptxThe next social challenge to public health:  the information environment.pptx
The next social challenge to public health: the information environment.pptxTina Purnat
 
Clinical Pharmacotherapy of Scabies Disease
Clinical Pharmacotherapy of Scabies DiseaseClinical Pharmacotherapy of Scabies Disease
Clinical Pharmacotherapy of Scabies DiseaseSreenivasa Reddy Thalla
 
Presentation on General Anesthetics pdf.
Presentation on General Anesthetics pdf.Presentation on General Anesthetics pdf.
Presentation on General Anesthetics pdf.Prerana Jadhav
 
Study on the Impact of FOCUS-PDCA Management Model on the Disinfection Qualit...
Study on the Impact of FOCUS-PDCA Management Model on the Disinfection Qualit...Study on the Impact of FOCUS-PDCA Management Model on the Disinfection Qualit...
Study on the Impact of FOCUS-PDCA Management Model on the Disinfection Qualit...MehranMouzam
 
CEHPALOSPORINS.pptx By Harshvardhan Dev Bhoomi Uttarakhand University
CEHPALOSPORINS.pptx By Harshvardhan Dev Bhoomi Uttarakhand UniversityCEHPALOSPORINS.pptx By Harshvardhan Dev Bhoomi Uttarakhand University
CEHPALOSPORINS.pptx By Harshvardhan Dev Bhoomi Uttarakhand UniversityHarshChauhan475104
 
Informed Consent Empowering Healthcare Decision-Making.pptx
Informed Consent Empowering Healthcare Decision-Making.pptxInformed Consent Empowering Healthcare Decision-Making.pptx
Informed Consent Empowering Healthcare Decision-Making.pptxSasikiranMarri
 
ANTI-DIABETICS DRUGS - PTEROCARPUS AND GYMNEMA
ANTI-DIABETICS DRUGS - PTEROCARPUS AND GYMNEMAANTI-DIABETICS DRUGS - PTEROCARPUS AND GYMNEMA
ANTI-DIABETICS DRUGS - PTEROCARPUS AND GYMNEMADivya Kanojiya
 
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...
Big Data Analysis Suggests COVID  Vaccination Increases Excess Mortality Of  ...Big Data Analysis Suggests COVID  Vaccination Increases Excess Mortality Of  ...
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...sdateam0
 
METHODS OF ACQUIRING KNOWLEDGE IN NURSING.pptx by navdeep kaur
METHODS OF ACQUIRING KNOWLEDGE IN NURSING.pptx by navdeep kaurMETHODS OF ACQUIRING KNOWLEDGE IN NURSING.pptx by navdeep kaur
METHODS OF ACQUIRING KNOWLEDGE IN NURSING.pptx by navdeep kaurNavdeep Kaur
 
SGK HÓA SINH NĂNG LƯỢNG SINH HỌC 2006.pdf
SGK HÓA SINH NĂNG LƯỢNG SINH HỌC 2006.pdfSGK HÓA SINH NĂNG LƯỢNG SINH HỌC 2006.pdf
SGK HÓA SINH NĂNG LƯỢNG SINH HỌC 2006.pdfHongBiThi1
 
Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdf
Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdfLippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdf
Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdfSreeja Cherukuru
 
World-Health-Day-2024-My-Health-My-Right.pptx
World-Health-Day-2024-My-Health-My-Right.pptxWorld-Health-Day-2024-My-Health-My-Right.pptx
World-Health-Day-2024-My-Health-My-Right.pptxEx WHO/USAID
 
MedDRA-A-Comprehensive-Guide-to-Standardized-Medical-Terminology.pdf
MedDRA-A-Comprehensive-Guide-to-Standardized-Medical-Terminology.pdfMedDRA-A-Comprehensive-Guide-to-Standardized-Medical-Terminology.pdf
MedDRA-A-Comprehensive-Guide-to-Standardized-Medical-Terminology.pdfSasikiranMarri
 
Nutrition of OCD for my Nutritional Neuroscience Class
Nutrition of OCD for my Nutritional Neuroscience ClassNutrition of OCD for my Nutritional Neuroscience Class
Nutrition of OCD for my Nutritional Neuroscience Classmanuelazg2001
 
medico legal aspects of wound - forensic medicine
medico legal aspects of wound - forensic medicinemedico legal aspects of wound - forensic medicine
medico legal aspects of wound - forensic medicinethanaram patel
 
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptx
COVID-19  (NOVEL CORONA  VIRUS DISEASE PANDEMIC ).pptxCOVID-19  (NOVEL CORONA  VIRUS DISEASE PANDEMIC ).pptx
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptxBibekananda shah
 
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptx
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptxSYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptx
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptxdrashraf369
 
Culture and Health Disorders Social change.pptx
Culture and Health Disorders Social change.pptxCulture and Health Disorders Social change.pptx
Culture and Health Disorders Social change.pptxDr. Dheeraj Kumar
 

Kürzlich hochgeladen (20)

Giftedness: Understanding Everyday Neurobiology for Self-Knowledge
Giftedness: Understanding Everyday Neurobiology for Self-KnowledgeGiftedness: Understanding Everyday Neurobiology for Self-Knowledge
Giftedness: Understanding Everyday Neurobiology for Self-Knowledge
 
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic Analysis
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic AnalysisVarSeq 2.6.0: Advancing Pharmacogenomics and Genomic Analysis
VarSeq 2.6.0: Advancing Pharmacogenomics and Genomic Analysis
 
The next social challenge to public health: the information environment.pptx
The next social challenge to public health:  the information environment.pptxThe next social challenge to public health:  the information environment.pptx
The next social challenge to public health: the information environment.pptx
 
Clinical Pharmacotherapy of Scabies Disease
Clinical Pharmacotherapy of Scabies DiseaseClinical Pharmacotherapy of Scabies Disease
Clinical Pharmacotherapy of Scabies Disease
 
Presentation on General Anesthetics pdf.
Presentation on General Anesthetics pdf.Presentation on General Anesthetics pdf.
Presentation on General Anesthetics pdf.
 
Study on the Impact of FOCUS-PDCA Management Model on the Disinfection Qualit...
Study on the Impact of FOCUS-PDCA Management Model on the Disinfection Qualit...Study on the Impact of FOCUS-PDCA Management Model on the Disinfection Qualit...
Study on the Impact of FOCUS-PDCA Management Model on the Disinfection Qualit...
 
CEHPALOSPORINS.pptx By Harshvardhan Dev Bhoomi Uttarakhand University
CEHPALOSPORINS.pptx By Harshvardhan Dev Bhoomi Uttarakhand UniversityCEHPALOSPORINS.pptx By Harshvardhan Dev Bhoomi Uttarakhand University
CEHPALOSPORINS.pptx By Harshvardhan Dev Bhoomi Uttarakhand University
 
Informed Consent Empowering Healthcare Decision-Making.pptx
Informed Consent Empowering Healthcare Decision-Making.pptxInformed Consent Empowering Healthcare Decision-Making.pptx
Informed Consent Empowering Healthcare Decision-Making.pptx
 
ANTI-DIABETICS DRUGS - PTEROCARPUS AND GYMNEMA
ANTI-DIABETICS DRUGS - PTEROCARPUS AND GYMNEMAANTI-DIABETICS DRUGS - PTEROCARPUS AND GYMNEMA
ANTI-DIABETICS DRUGS - PTEROCARPUS AND GYMNEMA
 
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...
Big Data Analysis Suggests COVID  Vaccination Increases Excess Mortality Of  ...Big Data Analysis Suggests COVID  Vaccination Increases Excess Mortality Of  ...
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...
 
METHODS OF ACQUIRING KNOWLEDGE IN NURSING.pptx by navdeep kaur
METHODS OF ACQUIRING KNOWLEDGE IN NURSING.pptx by navdeep kaurMETHODS OF ACQUIRING KNOWLEDGE IN NURSING.pptx by navdeep kaur
METHODS OF ACQUIRING KNOWLEDGE IN NURSING.pptx by navdeep kaur
 
SGK HÓA SINH NĂNG LƯỢNG SINH HỌC 2006.pdf
SGK HÓA SINH NĂNG LƯỢNG SINH HỌC 2006.pdfSGK HÓA SINH NĂNG LƯỢNG SINH HỌC 2006.pdf
SGK HÓA SINH NĂNG LƯỢNG SINH HỌC 2006.pdf
 
Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdf
Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdfLippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdf
Lippincott Microcards_ Microbiology Flash Cards-LWW (2015).pdf
 
World-Health-Day-2024-My-Health-My-Right.pptx
World-Health-Day-2024-My-Health-My-Right.pptxWorld-Health-Day-2024-My-Health-My-Right.pptx
World-Health-Day-2024-My-Health-My-Right.pptx
 
MedDRA-A-Comprehensive-Guide-to-Standardized-Medical-Terminology.pdf
MedDRA-A-Comprehensive-Guide-to-Standardized-Medical-Terminology.pdfMedDRA-A-Comprehensive-Guide-to-Standardized-Medical-Terminology.pdf
MedDRA-A-Comprehensive-Guide-to-Standardized-Medical-Terminology.pdf
 
Nutrition of OCD for my Nutritional Neuroscience Class
Nutrition of OCD for my Nutritional Neuroscience ClassNutrition of OCD for my Nutritional Neuroscience Class
Nutrition of OCD for my Nutritional Neuroscience Class
 
medico legal aspects of wound - forensic medicine
medico legal aspects of wound - forensic medicinemedico legal aspects of wound - forensic medicine
medico legal aspects of wound - forensic medicine
 
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptx
COVID-19  (NOVEL CORONA  VIRUS DISEASE PANDEMIC ).pptxCOVID-19  (NOVEL CORONA  VIRUS DISEASE PANDEMIC ).pptx
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptx
 
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptx
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptxSYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptx
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptx
 
Culture and Health Disorders Social change.pptx
Culture and Health Disorders Social change.pptxCulture and Health Disorders Social change.pptx
Culture and Health Disorders Social change.pptx
 

Primary post partum haemorrhage

  • 2. Overview…  Definition  Causes :  Uterine atony  Retained placenta  Genital tract trauma  Coagulation disorders  Risk Factors  Investigations  Emergency management  Specific management
  • 3. Introduction:  Obstetric haemorrhage remains one of the major causes of maternal death in both developed and developing countries.  In the 2003–2005 report of the UK Confidential Enquiries into Maternal Deaths, haemorrhage was the third highest direct cause of maternal death (6.6 deaths/million maternities).  Haemorrhage emerges as the major cause of severe maternal morbidity in almost all ‘near miss’ audits in both developed and developing countries Source: RCOG, Prevention and management of post partum haemorrhage 1st edition, 2009
  • 4. Definition of PPH:  Loss of 500 ml or more of blood from the genital tract within 24hours of the birth of a baby.  PPH can be minor (500–1000 ml) or major (more than 1000 ml)  Major could be divided to moderate (1000–2000 ml) or severe (more than 2000 ml). Source: RCOG, Prevention and management of post partum haemorrhage 1st edition, 2009
  • 5. Causes of primary PPH ( 4Ts)
  • 6. What are the risks of PPH? Source: RCOG, Prevention and management of post partum haemorrhage 1st edition, 2009)
  • 7. Source: RCOG, Prevention and management of post partum haemorrhage 1st edition, 2009)
  • 11. 3. Genital Tract Trauma  Bleeding from or into genital tract due to trauma to uterus, cervix, vagina & introitus.  bleeding can be profuse
  • 12.  Predisposing factors :  perineal tear,  episiotomies and ruptured vulval varicosities  Macrosomic babies,  Instrumental deliveries  Uterine rupture  Vaginal wall hematomas
  • 13. 4. Coagulation disorders  Predisposing factors  Amniotic fluid embolism  Abruptio placenta  Sepsis  Massive blood loss and transfusion  Severe PE  Chorioamnionitis  Idiopathic thrombocytopenia
  • 15.  Practical management of PPH may be considered as having at least four components:  communication with all relevant professionals;  resuscitation;  monitoring and investigation;  measures to arrest the bleeding Source: RCOG, Prevention and management of post partum haemorrhage 1st edition, 2009)
  • 16. 1. Who should be informed when the woman presents with PPH?  Basic measures for MINOR PPH (blood loss 500–1000 ml, no clinical shock):  Alert the midwife-in-charge.  Alert first-line obstetric and anaesthetic staff trained in the management of PPH.  Full protocol for MAJOR PPH (blood loss more than 1000 ml and continuing to bleed OR clinical shock):  Call experienced midwife (in addition to midwife in charge).  Call obstetric middle grade and alert consultant.  Call anaesthetic middle grade and alert consultant.  Alert consultant clinical haematologist on call.  Alert blood transfusion laboratory.  Call porters for delivery of specimens/blood.  Alert one member of the team to record events, fluids, drugs and vital signs. Source: RCOG, Prevention and management of post partum haemorrhage 1st edition, 2009)
  • 18. Clinical Presentation & Physiological Response to blood loss
  • 20.  Basic measures for MINOR PPH (blood loss 500–1000 ml, no clinical shock):  Intravenous access (14-gauge cannula x 1).  Commence crystalloid infusion.  Full protocol for MAJOR PPH (blood loss > 1000 ml and continuing to bleed OR clinical shock):  Assess airway. Assess breathing. Evaluate circulation  Oxygen by mask at 10–15 litres/minute. Intravenous access (14-gauge cannula x 2, orange cannulae).  Position flat. Keep the woman warm using appropriate available measures.  Transfuse blood as soon as possible.  Until blood is available, infuse up to 3.5 litres of warmed crystalloid Hartmann’s solution (2 litres) and/or colloid (1–2 litres) as rapidly as required.  The best equipment available should be used to achieve RAPID WARMED infusion of fluids.  Special blood filters should NOT be used, as they slow infusions.  Recombinant factor VIIa therapy should be based on the results of coagulation. Source: RCOG, Prevention and management of post partum haemorrhage 1st edition, 2009)
  • 21. Fluid therapy and blood product Crystalloid : Up to 2 litres Hartmann’s solution Colloid : Up to 1–2 litres colloid until blood arrives Blood : Cross matched. If crossmatched blood is still unavailable, give uncrossmatched group-specific blood OR give ‘O RhD negative’ blood Fresh frozen plasma : 4 units for every 6 units of red cells or prothrombin time/activated partial thromboplastin time > 1.5 x normal (12–15 ml/kg or total 1 litres) Platelets concentrates : if PLT count < 50 x 109 Cryoprecipitate : If fibrinogen < 1 g/l Source: RCOG, Prevention and management of post partum haemorrhage 1st edition, 2009)
  • 22. 2006 guideline from the British Committee for Standards in Haematology:  Main therapeutic goals of management of massive blood loss is to maintain:  haemoglobin > 8g/dl  platelet count > 75 x 109/l  prothrombin < 1.5 x mean control  activated prothrombin times < 1.5 x mean control  fibrinogen > 1.0 g/l Source: RCOG, Prevention and management of post partum haemorrhage 1st edition, 2009)
  • 23. 3. What investigations should be performed and how should the woman be monitored? Basic measures for MINOR PPH (blood loss 500–1000 ml, no clinical shock and bleeding ceasing):  Consider venepuncture (20 ml) for:  group and screen  full blood count  coagulation screen including fibrinogen  pulse and blood pressure recording every 15 minutes. Full Protocol for MAJOR PPH (blood loss greater than 1000ml and continuing to bleed OR clinical shock):  Consider venepuncture (20 ml) for: crossmatch (4 units minimum)  full blood count  coagulation screen including fibrinogen  renal and liver function for baseline. Source: RCOG, Prevention and management of post partum haemorrhage 1st edition, 2009)
  • 24. 4. Arrest the bleeding  Causes for PPH may be considered to relate to one or more of ‘the four Ts’:  tone (abnormalities of uterine contraction)  tissue (retained products of conception)  trauma (of the genital tract)  thrombin (abnormalities of coagulation). The most common cause of primary PPH is uterine atony. However, clinical examination must be undertaken to exclude other or additional causes:  retained products (placenta, membranes, clots)  vaginal/cervical lacerations or haematoma  ruptured uterus  broad ligament haematoma  extragenital bleeding (for example, subcapsular liver rupture)  uterine inversion. Source: RCOG, Prevention and management of post partum haemorrhage 1st edition, 2009)
  • 33. Manual Removal of Placenta
  • 35.
  • 37. Management of uterine atony IV Ergometrine (0.5mg x 2 doses IM Syntometrine 1mL (0.5 Ergometrine & 5 IU oxytocin Oxytocin (40 units in 500 mL NS at 40dpm IM Carboprost 250mcg (repeat after 15 min up to max 5 doses) Empty bladder Uterine massage/ compression IV access, fluids Placenta delivered & complete Observe/ monitor Continue oxytocin 6-12 hours Then off and observe Bleeding stops Uterine Atony Persistent bleeding 1) PGE-intrauterine, intramuscular, intravenous, intrarectal 2) PGF-2α-IM Carboprost (repeat after 15min up to max 5 doses) Uterine/ ovarian/ internal iliac artery ligation Uterine tamponade (b-lynch suture/ brace suture Hysterectomy

Hinweis der Redaktion

  1. Myomectomy  is the surgical removal of fibroids from the uterus placenta succenturia´ta  ,  succenturiate placenta  an accessory portion attached to the main placenta by an artery or vein placenta accre´ta   one abnormally adherent to the myometrium, with partial or complete absence of the decidua basalis. placenta pre´via   one located in the lower uterine segment, so that it partially or completely covers or adjoins the internal os.
  2. An  introitus  is an entrance that goes into a canal or hollow organ. The vaginal orifice is an  introitus