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M.Zayady
Management principles ofManagement principles of
odontogenic facial infectionsodontogenic facial infections
Dr. Mohammed El Sayed
OMF Consultant
2017
07/22/17 M.Zayady
07/22/17 M.Zayady
Clincal features
 Diffuse swelling
 Pain
 Fever
 Malaise
 Swelling is tense and tender
 Overlying skin is taut and shiny
 Trismus
 Regional lymph nodes are swollen and
tender
07/22/17 M.Zayady
The eight steps in the management of odontogenic
infections:
1.Determine the severity of infection.
2.Evaluate host defenses.
3.Decide on the setting of care.
4.Treat surgically.
5.Support medically.
6.Choose and prescribe antibiotic therapy.
7.Administer the antibiotic properly.
8.Evaluate the patient frequently.
07/22/17 M.Zayady
Step 1:
Determine the Severity of Infection
Three major factors must
be considered in
determining the severity
of an infection of the
head and neck:
Anatomic location,
Rate of progression,
Airway compromise.
07/22/17 M.Zayady
Anatomic Location
The anatomic spaces of the
head and neck can be
graded in severity by the
level to which they threaten
the airway or vital
structures, such as the
heart and mediastinum or
the cranial contents.
07/22/17 M.Zayady
Low severity
Buccal
Infraorbital
Vestibular
Subperiosteal
07/22/17 M.Zayady
Moderate severity
anatomic spaces that can hinder access to the
airway due to swelling or trismus
Masticatory space Submasseteric.
Pterygomandibular.
Superficial and Deep
temporal spaces.
Perimandibular spaces
)Submandibular, Submental, and Sublingual(.
07/22/17 M.Zayady
07/22/17 M.Zayady
07/22/17 M.Zayady
Ludwig’s angina??
07/22/17 M.Zayady
High severity
swelling can directly obstruct or
deviate the airway or
threaten vital structures.
Lateral pharyngeal
Retropharyngeal.
The danger space.
Mediastinum.
Cavernous sinus thrombosis
and other intracranial
infection also have high
severity.
07/22/17 M.Zayady
 Walls of the pharynx and
related structures:
 superior pharyngeal
constrictor (spc)
 middle pharyngeal
pharyngeal constrictor (mpc)
 inferior pharyngeal
constrictor (ipc)
 bodies of cervical vertebrae
(bcv)
 arrows point to the
retropharyngeal space
07/22/17 M.Zayady
Rate of Progression
07/22/17 M.Zayady
Necrotizing Fasciitis
rapidly progressive infection frequently due to
odontogenic sources, that follows the platysma muscle
down the neck and onto the anterior chest wall. Diabetes
and alcoholism have been shown to be significant
predisposing factors, whereas medical compromise,
delay in surgery, and mediastinitis are associated with
increased mortality. It can rapidly result in necrosis of
large amounts of muscle, subcutaneous tissue, and skin,
resulting in severe reconstructive defects. The earliest
signs of necrotizing fasciitis are small vesicles and a
dusky purple discoloration of the involved skin
07/22/17 M.Zayady
Airway Compromise
Complete airway obstruction
- Endotracheal intubation
- Cricothyroidotomy or Tracheotomy
partial airway obstruction
breath sounds special posture
07/22/17 M.Zayady
Trismus???
A maximum interincisal
opening that has
decreased to 20 mm or
less in a patient with acute
pain should be considered
an infection of the
masticator space until
proved otherwise.
07/22/17 M.Zayady
07/22/17 M.Zayady
Assessing the effectiveness
of respiratory efforts
Pulse oximeter: An oxygen saturation of below 94% in an
otherwise healthy patient is indeed an ominous sign
because it indicates insufficient oxygenation of the
tissues due to hypoperfusion or hypooxygenation.
Soft tissue radiographs: of the cervical airway and chest can
be quite valuable in identifying deviation of the airway
laterally on a posteroanterior film or anterior
displacement of the airway on a lateral view.
07/22/17 M.Zayady
Cont.
The newer high-speed
CT scanners: can
obtain a computerized
CT examination within
seconds to minutes,
07/22/17 M.Zayady
Step 2:
Evaluate Host Defenses
The medical conditions that can interfere with proper
function of the immune system:
 Diabetes
 Steroid therapy
 Organ transplants
 Malignancy
 Chemotherapy
 Chronic renal disease
 Malnutrition
 Alcoholism
 End-stage AIDS
07/22/17 M.Zayady
Systemic Reserve
The host response to severe infection can place a
severe physiologic load on the body. Fever can
increase sensible and insensible fluid losses and
caloric requirements. A prolonged fever may
cause dehydration, which can therefore
decrease cardiovascular reserves and deplete
glycogen stores, shifting the body metabolism to
a catabolic state.
07/22/17 M.Zayady
The physiologic stress of a serious
infection can disrupt previously well
established control of systemic diseases.
07/22/17 M.Zayady
Step 3:
Decide on the Setting of Care
Indications for hospital admission of the patient
with a severe odontogenic infection:
 Temperature > 101°F (38.3°C)
 Dehydration
 Threat to the airway or vital structures
 Infection in moderate or high severity anatomic spaces
 Need for general anesthesia
 Need for inpatient control of systemic disease
07/22/17 M.Zayady
Immediateestablishment of airway security and early
aggressivesurgical therapy arethemost
important intervention stepsin themanagement
of severeodontogenic infections.
Indications for an operating room procedure.
 To establish airway security
 Moderate to high anatomic severity
 Multiple space involvement
 Rapidly progressing infection
 Need for general anesthesia
Step 4:
Treat Surgically
07/22/17 M.Zayady
Needle decompression tech.?
 Decompress the surrounding tissues.
 Decrease the risk of abscess rupture through taut,
distended oropharyngeal tissues during
instrumentation of the airway.
 Redirection of pus drainage into the oral cavity or
onto the skin, where it can easily be removed,
 Obtaining an excellent specimen for culture and
sensitivity testing.
07/22/17 M.Zayady
Surgical Drainage
07/22/17 M.Zayady
07/22/17 M.Zayady
Culture and Sensitivity Testing
 When an infection involves anatomic spaces of
moderate or greater severity.
 When there is significant medical or immune
system compromise.
 When the surgeon is dealing with infections that
have been subjected to multiple prior courses of
antibiotic therapy.
 In chronic infections that are resistant to therapy.
07/22/17 M.Zayady
07/22/17 M.Zayady
Step 5:
Support Medically
 Hydration.
 Nutrition. in all patients
 Control of fever.
 Maintenance or reestablishment of electrolyte
balance . some patients
 Control of systemic diseases
07/22/17 M.Zayady
Daily sensiblefluid loss, consisting primarily of sweat, is
increased by 250 mL per degreeof fever. Insensiblefluid
loss, consisting mainly of evaporation from lungsand skin, is
increased by 50 to 75 mL per degreeof fever per day.
Fever also increasesmetabolic demand by 5 to 8% per degree
of fever per day.
07/22/17 M.Zayady
Step 6:
Choose and Prescribe antibiotic Therapy
Severity of Infection Antibiotic of Choice
Outpatient Penicillin
Clindamycin
Cephalexin (only if the penicillin allergy was not the
anaphylactoid type; use caution)
Penicillin allergy:
Clindamycin
Moxifloxacin
Metronidazole alone
Inpatient Clindamycin
Ampicillin + metronidazole
Ampicillin + sulbactam
Penicillin allergy:
Clindamycin
Third-generation cephalosporin IV
(only if the penicillin
allergy was not the anaphylactoid type; use caution)
Moxifloxacin (especially for Eikenella corrodens)
Metronidazole alone (if neither clindamycin nor
cephalosporins can be tolerated)
07/22/17 M.Zayady
Step 7:
Administer the antibiotic Properly
 Dose
 Route
 Duration
07/22/17 M.Zayady
Step 8:
Evaluate the Patient Frequently
 Daily clinical evaluation and wound care.
 By 2 to 3 postoperative days the clinical signs of
improvement should be apparent:
- Decreasing swelling.
- Defervescence.
- Cessation of wound drainage.
- Declining white blood cell count.
- Decreased malaise.
- Decrease in airway swelling
07/22/17 M.Zayady
Causes of Treatment Failure
 Inadequate surgery
 Depressed host defenses
 Foreign body
 Antibiotic problems
Patient noncompliance
Drug not reaching site
Drug dosage too low
Wrong bacterial diagnosis
Wrong antibiotic
07/22/17 M.Zayady

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Principles of management of odontogenic infections

  • 1. M.Zayady Management principles ofManagement principles of odontogenic facial infectionsodontogenic facial infections Dr. Mohammed El Sayed OMF Consultant 2017
  • 3. 07/22/17 M.Zayady Clincal features  Diffuse swelling  Pain  Fever  Malaise  Swelling is tense and tender  Overlying skin is taut and shiny  Trismus  Regional lymph nodes are swollen and tender
  • 4. 07/22/17 M.Zayady The eight steps in the management of odontogenic infections: 1.Determine the severity of infection. 2.Evaluate host defenses. 3.Decide on the setting of care. 4.Treat surgically. 5.Support medically. 6.Choose and prescribe antibiotic therapy. 7.Administer the antibiotic properly. 8.Evaluate the patient frequently.
  • 5. 07/22/17 M.Zayady Step 1: Determine the Severity of Infection Three major factors must be considered in determining the severity of an infection of the head and neck: Anatomic location, Rate of progression, Airway compromise.
  • 6. 07/22/17 M.Zayady Anatomic Location The anatomic spaces of the head and neck can be graded in severity by the level to which they threaten the airway or vital structures, such as the heart and mediastinum or the cranial contents.
  • 8. 07/22/17 M.Zayady Moderate severity anatomic spaces that can hinder access to the airway due to swelling or trismus Masticatory space Submasseteric. Pterygomandibular. Superficial and Deep temporal spaces. Perimandibular spaces )Submandibular, Submental, and Sublingual(.
  • 12. 07/22/17 M.Zayady High severity swelling can directly obstruct or deviate the airway or threaten vital structures. Lateral pharyngeal Retropharyngeal. The danger space. Mediastinum. Cavernous sinus thrombosis and other intracranial infection also have high severity.
  • 13. 07/22/17 M.Zayady  Walls of the pharynx and related structures:  superior pharyngeal constrictor (spc)  middle pharyngeal pharyngeal constrictor (mpc)  inferior pharyngeal constrictor (ipc)  bodies of cervical vertebrae (bcv)  arrows point to the retropharyngeal space
  • 15. 07/22/17 M.Zayady Necrotizing Fasciitis rapidly progressive infection frequently due to odontogenic sources, that follows the platysma muscle down the neck and onto the anterior chest wall. Diabetes and alcoholism have been shown to be significant predisposing factors, whereas medical compromise, delay in surgery, and mediastinitis are associated with increased mortality. It can rapidly result in necrosis of large amounts of muscle, subcutaneous tissue, and skin, resulting in severe reconstructive defects. The earliest signs of necrotizing fasciitis are small vesicles and a dusky purple discoloration of the involved skin
  • 16. 07/22/17 M.Zayady Airway Compromise Complete airway obstruction - Endotracheal intubation - Cricothyroidotomy or Tracheotomy partial airway obstruction breath sounds special posture
  • 17. 07/22/17 M.Zayady Trismus??? A maximum interincisal opening that has decreased to 20 mm or less in a patient with acute pain should be considered an infection of the masticator space until proved otherwise.
  • 19. 07/22/17 M.Zayady Assessing the effectiveness of respiratory efforts Pulse oximeter: An oxygen saturation of below 94% in an otherwise healthy patient is indeed an ominous sign because it indicates insufficient oxygenation of the tissues due to hypoperfusion or hypooxygenation. Soft tissue radiographs: of the cervical airway and chest can be quite valuable in identifying deviation of the airway laterally on a posteroanterior film or anterior displacement of the airway on a lateral view.
  • 20. 07/22/17 M.Zayady Cont. The newer high-speed CT scanners: can obtain a computerized CT examination within seconds to minutes,
  • 21. 07/22/17 M.Zayady Step 2: Evaluate Host Defenses The medical conditions that can interfere with proper function of the immune system:  Diabetes  Steroid therapy  Organ transplants  Malignancy  Chemotherapy  Chronic renal disease  Malnutrition  Alcoholism  End-stage AIDS
  • 22. 07/22/17 M.Zayady Systemic Reserve The host response to severe infection can place a severe physiologic load on the body. Fever can increase sensible and insensible fluid losses and caloric requirements. A prolonged fever may cause dehydration, which can therefore decrease cardiovascular reserves and deplete glycogen stores, shifting the body metabolism to a catabolic state.
  • 23. 07/22/17 M.Zayady The physiologic stress of a serious infection can disrupt previously well established control of systemic diseases.
  • 24. 07/22/17 M.Zayady Step 3: Decide on the Setting of Care Indications for hospital admission of the patient with a severe odontogenic infection:  Temperature > 101°F (38.3°C)  Dehydration  Threat to the airway or vital structures  Infection in moderate or high severity anatomic spaces  Need for general anesthesia  Need for inpatient control of systemic disease
  • 25. 07/22/17 M.Zayady Immediateestablishment of airway security and early aggressivesurgical therapy arethemost important intervention stepsin themanagement of severeodontogenic infections. Indications for an operating room procedure.  To establish airway security  Moderate to high anatomic severity  Multiple space involvement  Rapidly progressing infection  Need for general anesthesia Step 4: Treat Surgically
  • 26. 07/22/17 M.Zayady Needle decompression tech.?  Decompress the surrounding tissues.  Decrease the risk of abscess rupture through taut, distended oropharyngeal tissues during instrumentation of the airway.  Redirection of pus drainage into the oral cavity or onto the skin, where it can easily be removed,  Obtaining an excellent specimen for culture and sensitivity testing.
  • 29. 07/22/17 M.Zayady Culture and Sensitivity Testing  When an infection involves anatomic spaces of moderate or greater severity.  When there is significant medical or immune system compromise.  When the surgeon is dealing with infections that have been subjected to multiple prior courses of antibiotic therapy.  In chronic infections that are resistant to therapy.
  • 31. 07/22/17 M.Zayady Step 5: Support Medically  Hydration.  Nutrition. in all patients  Control of fever.  Maintenance or reestablishment of electrolyte balance . some patients  Control of systemic diseases
  • 32. 07/22/17 M.Zayady Daily sensiblefluid loss, consisting primarily of sweat, is increased by 250 mL per degreeof fever. Insensiblefluid loss, consisting mainly of evaporation from lungsand skin, is increased by 50 to 75 mL per degreeof fever per day. Fever also increasesmetabolic demand by 5 to 8% per degree of fever per day.
  • 33. 07/22/17 M.Zayady Step 6: Choose and Prescribe antibiotic Therapy Severity of Infection Antibiotic of Choice Outpatient Penicillin Clindamycin Cephalexin (only if the penicillin allergy was not the anaphylactoid type; use caution) Penicillin allergy: Clindamycin Moxifloxacin Metronidazole alone Inpatient Clindamycin Ampicillin + metronidazole Ampicillin + sulbactam Penicillin allergy: Clindamycin Third-generation cephalosporin IV (only if the penicillin allergy was not the anaphylactoid type; use caution) Moxifloxacin (especially for Eikenella corrodens) Metronidazole alone (if neither clindamycin nor cephalosporins can be tolerated)
  • 34. 07/22/17 M.Zayady Step 7: Administer the antibiotic Properly  Dose  Route  Duration
  • 35. 07/22/17 M.Zayady Step 8: Evaluate the Patient Frequently  Daily clinical evaluation and wound care.  By 2 to 3 postoperative days the clinical signs of improvement should be apparent: - Decreasing swelling. - Defervescence. - Cessation of wound drainage. - Declining white blood cell count. - Decreased malaise. - Decrease in airway swelling
  • 36. 07/22/17 M.Zayady Causes of Treatment Failure  Inadequate surgery  Depressed host defenses  Foreign body  Antibiotic problems Patient noncompliance Drug not reaching site Drug dosage too low Wrong bacterial diagnosis Wrong antibiotic