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Product
Discussion
MD. MUNIRUL SALEHIN
EXECUTIVE, PMD
LABAID LTD. (DIAGNOSTIC)
+88 01676394488
Infertility?
Not conceiving after 12 months of regular sexual
intercourse without the use of birth control.
However, for women aged 35 and older, inability to conceive after 6 months
is generally considered infertility.
Types of Infertility
 Primary Infertility/Subfertility
who have not become pregnant after at
least 1 year having sex without using birth
control methods.
 Secondary Infertility
couples who have been able to get pregnant
at least once, but now are unable.
Infertility Rate
 8% to 12% of couples worldwide are infertile
The actual rate of infertility in Bangladesh is still unknown.
Causes of Infertility
30%
30%
20%
20%
Male
Female
Both
Unexplained
Male Infertility
A medical condition:
• This could be a testicular infection, cancer or surgery.
Semen and sperm:
Low sperm count
Abnormal sperm
Low sperm mobility (motility)
 Overheated testicles: Use hot tubs,
wearing tight clothes, and working in hot.
 Ejaculation disorders: If the ejaculatory
ducts are blocked, semen may be
ejaculated into the bladder.
 Hormonal imbalance: Hypogonadism
(testosterone deficiency).
Other causes
• Genetic factors
• Radiation therapy
• Chemotherapy
• Some diseases: Anemia, Cushing’s
syndrome, diabetes and thyroid disease
Risk Factor of Male Infertility
 Semen analysis (WHO Guideline)
 Biochemical test (CBC, P. Sugar)
 Hormone test (Testosterone, FSH, LH)
 Molecular diagnosis (Karyotyping, y-chromosomal microdilution)
 Cytopathology (FNAC, Biopsy)
 Serological test
 Imaging test etc.
Test we can promote
Female Infertility
 Ovulation disorders: The ovaries stop working before the age of 40 years
 Problems in the uterus or fallopian tubes can prevent the
egg from traveling from the ovary to the uterus
 Chronic conditions: These include AIDS or cancer
PCOS Prolactin
Poor egg
quality
Thyroid
problem
Endometr
iosis
Risk Factor of Female Infertility.
NSAIDs
Non-steroidal
anti-
inflammatory
drug long-term
use of aspirin or
ibuprofen may
make it harder
to conceive
.
Chemo-
Therapy
.
Radiation
- therapy
Illegal drugs
Cholesterol
Some women who use
marijuana or cocaine may have
fertility problems
One study has found that high
cholesterol levels may have an
impact on fertility in women
Test we can promote
Biochemical test (CBC, P. Sugar, Creatinine, SGPT)
Hormone test (Prolactin, FSH, LH, E2 etc.)
AMH, Vitamin-D, Prothrombin time, APTT, Lupus Anticoagulant
PGx (MTHFR), Torch Panel, HPV DNA
Hysterosalphingogram (HSG)
Molecular diagnosis (Karyotyping)
Cytopathology (Pap’s Smear)
Imaging test
Cryopreservation etc.
Treatment
Frequency of intercourse
• Sperm can survive inside the female for up
to 5 days, while an egg can be fertilized for
up to 1 day after ovulation.
Fertility treatments for men
• Premature ejaculation, Blockage of the
ejaculatory duct
• Retrograde ejaculation, Surgery for
epididymal blockage
 Fertility treatments for women
• Clomifene, Metformin, Human
menopausal gonadotropin, Follicle-
stimulating hormone, Human
chorionic gonadotropin,
Gonadotropin-releasing hormone
(Gn-RH)
• Reducing the risk of multiple
pregnancies
• Surgical procedures
Treatment
Assisted conception (ART)
• In-vitro fertilization (IVF)
• Intracytoplasmic sperm injection (ICSI)
• Intrauterine insemination (IUI)
• Sperm or egg donation
• Surgical sperm aspiration
• Cryopreservation
Normal Pregnancy
Intrauterine Insemination (IUI)
In-Vitro Fertilization (IVF)/Test-tube Baby
In-Vitro: In glass
Fertilization: Ova + Sperm
In-Vitro Fertilization (IVF)
In-vitro fertilization (IVF) TEST TUBE*
Intracytoplasmic Sperm Injection (ICSI)
Cryopreservation (Embryo, Egg & Sperm Bank)
Embryo Freezing
Cryopreservation of Ova, Sperm and Embryo
Cancer PatientSperm and ovum collection, preservation
from Husband-wife, unmarried, childless
couple or willing to have more children
before their cancer treatment.
Sperm collected from husband working
abroad and subsequently, the test tube
baby (IVF) method use the sperm for the
pregnancy of the wife.
Extra embryo reserves collected through
the Test Tube Baby (IVF) method.
Success Rate
Currently, success rate of Assisted
Reproductive Technologies (ART) is
AGE
Success
Rate
< 34 40 %
35-37 31 %
38-40 21 %
41-42 11 %
> 43 5%
40 %
World First Test Tube Baby
Robert Edwards & Patrick Steptoe
25 July 1978
Oldham General Hospital, Greater Manchester, UK.
LOUISE JOY BROWN
Target Doctor
Infertility Specialist
Gynecologist & Obstetrician
Endocrinologist
Urologist & Andrologist
Oncologist
General Practitioners (GP)
AWARENESS
Cost (Labaid)
SL PROCEDURE PRICE (BDT)
01 In Vitro Fertilization-IVF/ICSI
02 Intra-Uterine Insemination (IUI)
Intra-Uterine Insemination (IUI) Double***
03 Semen Analysis
04 Folicullometry
05 TESA/PESA
06 Cryopreservation /Embryo, Ovam & Sparm Bank***
Product presentation (labaid fertility center).li

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Product presentation (labaid fertility center).li

  • 1. Product Discussion MD. MUNIRUL SALEHIN EXECUTIVE, PMD LABAID LTD. (DIAGNOSTIC) +88 01676394488
  • 3. Not conceiving after 12 months of regular sexual intercourse without the use of birth control. However, for women aged 35 and older, inability to conceive after 6 months is generally considered infertility.
  • 4. Types of Infertility  Primary Infertility/Subfertility who have not become pregnant after at least 1 year having sex without using birth control methods.  Secondary Infertility couples who have been able to get pregnant at least once, but now are unable.
  • 5. Infertility Rate  8% to 12% of couples worldwide are infertile The actual rate of infertility in Bangladesh is still unknown.
  • 7. Male Infertility A medical condition: • This could be a testicular infection, cancer or surgery. Semen and sperm: Low sperm count Abnormal sperm Low sperm mobility (motility)
  • 8.  Overheated testicles: Use hot tubs, wearing tight clothes, and working in hot.  Ejaculation disorders: If the ejaculatory ducts are blocked, semen may be ejaculated into the bladder.  Hormonal imbalance: Hypogonadism (testosterone deficiency). Other causes • Genetic factors • Radiation therapy • Chemotherapy • Some diseases: Anemia, Cushing’s syndrome, diabetes and thyroid disease
  • 9. Risk Factor of Male Infertility
  • 10.  Semen analysis (WHO Guideline)  Biochemical test (CBC, P. Sugar)  Hormone test (Testosterone, FSH, LH)  Molecular diagnosis (Karyotyping, y-chromosomal microdilution)  Cytopathology (FNAC, Biopsy)  Serological test  Imaging test etc. Test we can promote
  • 11. Female Infertility  Ovulation disorders: The ovaries stop working before the age of 40 years  Problems in the uterus or fallopian tubes can prevent the egg from traveling from the ovary to the uterus  Chronic conditions: These include AIDS or cancer PCOS Prolactin Poor egg quality Thyroid problem Endometr iosis
  • 12. Risk Factor of Female Infertility. NSAIDs Non-steroidal anti- inflammatory drug long-term use of aspirin or ibuprofen may make it harder to conceive . Chemo- Therapy . Radiation - therapy Illegal drugs Cholesterol Some women who use marijuana or cocaine may have fertility problems One study has found that high cholesterol levels may have an impact on fertility in women
  • 13. Test we can promote Biochemical test (CBC, P. Sugar, Creatinine, SGPT) Hormone test (Prolactin, FSH, LH, E2 etc.) AMH, Vitamin-D, Prothrombin time, APTT, Lupus Anticoagulant PGx (MTHFR), Torch Panel, HPV DNA Hysterosalphingogram (HSG) Molecular diagnosis (Karyotyping) Cytopathology (Pap’s Smear) Imaging test Cryopreservation etc.
  • 14. Treatment Frequency of intercourse • Sperm can survive inside the female for up to 5 days, while an egg can be fertilized for up to 1 day after ovulation. Fertility treatments for men • Premature ejaculation, Blockage of the ejaculatory duct • Retrograde ejaculation, Surgery for epididymal blockage  Fertility treatments for women • Clomifene, Metformin, Human menopausal gonadotropin, Follicle- stimulating hormone, Human chorionic gonadotropin, Gonadotropin-releasing hormone (Gn-RH) • Reducing the risk of multiple pregnancies • Surgical procedures
  • 15. Treatment Assisted conception (ART) • In-vitro fertilization (IVF) • Intracytoplasmic sperm injection (ICSI) • Intrauterine insemination (IUI) • Sperm or egg donation • Surgical sperm aspiration • Cryopreservation
  • 19. In-Vitro: In glass Fertilization: Ova + Sperm In-Vitro Fertilization (IVF)
  • 22. Cryopreservation (Embryo, Egg & Sperm Bank) Embryo Freezing Cryopreservation of Ova, Sperm and Embryo
  • 23. Cancer PatientSperm and ovum collection, preservation from Husband-wife, unmarried, childless couple or willing to have more children before their cancer treatment. Sperm collected from husband working abroad and subsequently, the test tube baby (IVF) method use the sperm for the pregnancy of the wife. Extra embryo reserves collected through the Test Tube Baby (IVF) method.
  • 24. Success Rate Currently, success rate of Assisted Reproductive Technologies (ART) is AGE Success Rate < 34 40 % 35-37 31 % 38-40 21 % 41-42 11 % > 43 5% 40 %
  • 25. World First Test Tube Baby Robert Edwards & Patrick Steptoe 25 July 1978 Oldham General Hospital, Greater Manchester, UK. LOUISE JOY BROWN
  • 26. Target Doctor Infertility Specialist Gynecologist & Obstetrician Endocrinologist Urologist & Andrologist Oncologist General Practitioners (GP) AWARENESS
  • 27. Cost (Labaid) SL PROCEDURE PRICE (BDT) 01 In Vitro Fertilization-IVF/ICSI 02 Intra-Uterine Insemination (IUI) Intra-Uterine Insemination (IUI) Double*** 03 Semen Analysis 04 Folicullometry 05 TESA/PESA 06 Cryopreservation /Embryo, Ovam & Sparm Bank***