Lect 6-inf bowel dis
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inflammatory bowel disease
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Lect 6-inf bowel dis
- 1. INFLAMMATORY BOWEL DISEASE SMS 2044
- 2. INFLAMMATORY BOWEL DISEASE IBD is a group of inflammatory conditions of large intestine ,in some cases small intestine.
- 6. Different Clinical, Endoscopic, and Radiographic Features of Crohn’s & Ulcerative Colitis Ulcerative Colitis Crohn's Disease CLINICAL Gross blood in stool Yes Occasionally Mucus Yes Occasionally Systemic symptoms Occasionally Frequently Pain Occasionally Frequently Abdominal mass Rarely Yes Significant perineal disease No Frequently Fistulas No Yes Small intestinal obstruction No Frequently Colonic obstruction Rarely Frequently Response to antibiotics No Yes Recurrence after surgery No Yes ANCA-positive Frequently Rarely
- 7. Ulcerative Colitis Crohn's Disease ENDOSCOPIC Rectal sparing Rarely Frequently Continuous disease Yes Occasionally "Cobblestoning" No Yes Granuloma on biopsy No Occasionally RADIOGRAPHIC Small bowel significantly abnormal No Yes Abnormal terminal ileum Occasionally Yes Segmental colitis No Yes Asymmetrical colitis No Yes Stricture Occasionally Frequently
- 8. Intestines - Pathology Idiopathic Inflammatory Bowel Diseases (CD) (UC) Fissuring Ulcer noncaseating granulomas
- 18. Patients with ulcerative colitis can occasionally have aphthous ulcers involving the tongue, lips , palate and pharynx Endoscopic image of ulcerative colitis showing loss of vascular pattern of the sigmoid colon, granularity and some friability of the mucosa.
- 25. H&E stain of a colonic biopsy showing a crypt abscess:a classic finding in ulcerative colitis [ edit ] General
- 26. Crohn's Disease
- 40. f) chronic course may lead to: i) fibrosing strictures - terminal ileum - fistulas other areas ii) protein loss iii) Vit B 12 loss iv) bile salt loss - steatorrhea v) linear serpentine ulcers www.freelivedoctor.com
- 48. Comparison of UC and CD ULCERATIVE COLITIS CROHN’S Age Any Any Sex m=f M=f Anatomical distribution Colon only Any part of G.I Presentation Bloody diarrhoea Variable; pain diarrhoea, Weight loss Risk factors more common in non smokers More common in smokers
- 49. Treatment of Inflammatory Bowel Disease
Hinweis der Redaktion
- Crohn's disease shows a transmural pattern of inflammation , meaning that the inflammation may span the entire depth of the intestinal wall. [1]
- Slide 5 Ideally, treatment for active Crohn's disease should rapidly improve symptoms. Non-specific anti-inflammatory drugs are the mainstay of treatment for Crohn's disease. Examples are: glucocorticoids 5-aminosalicylates (5-ASA) immunosuppressants antimetabolites methotrexate.