SlideShare ist ein Scribd-Unternehmen logo

心血管药理

•Als PPS, PDF herunterladen•
•
L
laowantong

刘俊田编制

1 von 172
心 血 管 药 理 (cardiovascular pharmacology) 刘俊田 82655188 （ O ） [email_address] office ： No.916 ， 9 th floor ， Library Building
第 24 章 作用于心血管系统离子通道的药物 ( drugs acting on ion channels in cardiovascular system )
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
 
第二节 作用于心血管系统离子通道的药物 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
（二）钙拮抗药 （ calcium antagonist ） ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第 25 章 抗心律失常药  (antiarrhythmic agents) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第一节 心肌的电生理特性 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
第一节 心肌的电生理特性 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
第一节 心肌的电生理特性 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
第二节 心律失常发生机制 ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
折返激动（ reentry ）发生机制 正常心肌 单向传导阻滞 折返形成
 
[object Object],[object Object]
第三节 抗心律失常药的基本电生理作用 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第四节 抗心律失常药的分类 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
第五节 抗心律失常药 的主要不良反应 ,[object Object],[object Object]
第六节 常用抗心律失常药 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
0mV -85mV 0 1 2 3 4 ADP ERP
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
0mV -85mV 0 1 2 3 4 ADP ERP
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第 27 章 抗慢性充血性心力衰竭药 [Drugs used in treatment of chronic congestive heart failure(CHF)] ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
概 论 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
概 论 1. 概述：心功能不全又称心力衰竭，是指在各种病理因素作用下心脏循环功能受损，导致心输出量不能满足机体的需要而产生的综合征。 2. 心功能不全发生的病理生理过程。* 3. 影响心功能的因素 : 心肌收缩性 , 心率 , 心脏前后负荷。 4. 心功能不全的分型及抗心功能不全药物的分类 (1) 急性心功能不全：镇痛药；强心药；血管扩张药；强效利尿药。 (2) 慢性心功能不全：强心药，血管扩张药，利尿药， ACEI ， β 受体阻断剂等。
 
概 论 1. 概述：心功能不全又称心力衰竭，是指在各种病理因素作用下心脏循环功能受损，导致心输出量不能满足机体的需要而产生的综合征。 2. 心功能不全发生的病理生理过程。 3. 影响心功能的因素 : 心肌收缩性 , 心率 , 心脏前后负荷。 4. 药物治疗史： 洋地黄类->利尿药（ 50 年代）->血管扩张药（ 70 年代）->其他强心药（ 70 年代末）-> ACEI （ 80 年代）-> β 受体阻滞药（ 90 年代后期）-> AVP 受体拮抗药， ET 受体拮抗药等
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第一节 RAAI ( renin-angiotensin-aldosterone inhibitor ) ,[object Object],[object Object],[object Object],[object Object]
顺应性↑ 血管紧张素Ⅱ ↓ 缓激肽 分解↓ 心室、主动脉 肥厚↓ 醛固酮分泌↓ 血容量↓ 血管扩张 血压 ↑ 激肽释放酶 肾素 血管紧张素原 激肽原 血管紧张素Ⅰ 缓激肽↑ PGI 2 ↑ PGE 2 ↑ EDHF ↑ NO ↑ 血管紧张素转化酶 ACEI ( 抑制 ) 血管扩张
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第二节 利尿药 (diuretics) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第三节 β 受体阻断药 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第四节 强心药 (cardiotonic agents) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
评 价 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
二、 β 受体激动剂 (β receptor agonists) ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
三、磷酸二酯酶抑制剂 (PDEI) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
四、钙增敏剂（ calcium sensitizer ） ,[object Object],[object Object],[object Object],[object Object],[object Object]
第五节 血管扩张药 (vasodilators) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
第 28 章 抗心绞痛药 (antianginal drugs) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第一节 硝酸酯类 (nitrates) ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第二节 β 受体阻断剂 (βreceptor blockers) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第三节 钙通道阻滞药 (calcium antagonists) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第 29 章 抗动脉粥样硬化药 (anti-atherosclerotic drugs) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第一节 调血脂药 （ lipidemic-modulating drugs ） ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第 30 章 抗高血压药 (antihypertensive drugs ， hypotensive drugs) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object]
第一节 抗高血压药物的分类 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第三节 肾素 - 血管紧张素抑制药 （ renin-angiotensin inhibitors ） ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
顺应性↑ 血管紧张素Ⅱ ↓ 缓激肽 分解↓ 心室、主动脉 肥厚↓ 醛固酮分泌↓ 血容量↓ 血管扩张 血压 ↑ 激肽释放酶 肾素 血管紧张素原 激肽原 血管紧张素Ⅰ 缓激肽↑ PGI 2 ↑ PGE 2 ↑ EDHF ↑ NO ↑ 血管紧张素转化酶 ACEI ( 抑制 ) 血管扩张
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第四节 交感神经抑制药 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第五节钙拮抗药 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第六节 其他血管扩张药 ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
第十节 抗高血压药的合理应用 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Thanks for your cooperation ！

Empfohlen

抗心律失常药物治疗进展
抗心律失常药物治疗进展抗心律失常药物治疗进展
抗心律失常药物治疗进展zhijun sun
 
Basic Cardiac Electrophysiology and ECG Concepts_20120916_南區
Basic Cardiac Electrophysiology and ECG Concepts_20120916_南區Basic Cardiac Electrophysiology and ECG Concepts_20120916_南區
Basic Cardiac Electrophysiology and ECG Concepts_20120916_南區Taiwan Heart Rhythm Society
 
陈文劲：生命支持和脑灌注--神经重症病例讨论
陈文劲：生命支持和脑灌注--神经重症病例讨论陈文劲：生命支持和脑灌注--神经重症病例讨论
陈文劲：生命支持和脑灌注--神经重症病例讨论neuroccm
 
回顧心臟電生理學 Review of cardiac electrophysiology
回顧心臟電生理學 Review of cardiac electrophysiology回顧心臟電生理學 Review of cardiac electrophysiology
回顧心臟電生理學 Review of cardiac electrophysiology元傑 張
 
藥物中毒之臨床藥事照顧經驗(完整版)
藥物中毒之臨床藥事照顧經驗(完整版)藥物中毒之臨床藥事照顧經驗(完整版)
藥物中毒之臨床藥事照顧經驗(完整版)Ming Chia Lee
 
第二篇 第十四章 呼吸衰竭
第二篇 第十四章 呼吸衰竭第二篇 第十四章 呼吸衰竭
第二篇 第十四章 呼吸衰竭yansongfan
 
肝硬化病人之用藥調整 實證文獻回顧
肝硬化病人之用藥調整 實證文獻回顧肝硬化病人之用藥調整 實證文獻回顧
肝硬化病人之用藥調整 實證文獻回顧Ming Chia Lee
 
chapter4 Blood Circle
chapter4 Blood Circlechapter4 Blood Circle
chapter4 Blood CircleLuohe Medical College
 

Empfohlen

抗心律失常药物治疗进展
抗心律失常药物治疗进展抗心律失常药物治疗进展
抗心律失常药物治疗进展zhijun sun
 
Basic Cardiac Electrophysiology and ECG Concepts_20120916_南區
Basic Cardiac Electrophysiology and ECG Concepts_20120916_南區Basic Cardiac Electrophysiology and ECG Concepts_20120916_南區
Basic Cardiac Electrophysiology and ECG Concepts_20120916_南區Taiwan Heart Rhythm Society
 
陈文劲：生命支持和脑灌注--神经重症病例讨论
陈文劲：生命支持和脑灌注--神经重症病例讨论陈文劲：生命支持和脑灌注--神经重症病例讨论
陈文劲：生命支持和脑灌注--神经重症病例讨论neuroccm
 
回顧心臟電生理學 Review of cardiac electrophysiology
回顧心臟電生理學 Review of cardiac electrophysiology回顧心臟電生理學 Review of cardiac electrophysiology
回顧心臟電生理學 Review of cardiac electrophysiology元傑 張
 
藥物中毒之臨床藥事照顧經驗(完整版)
藥物中毒之臨床藥事照顧經驗(完整版)藥物中毒之臨床藥事照顧經驗(完整版)
藥物中毒之臨床藥事照顧經驗(完整版)Ming Chia Lee
 
第二篇 第十四章 呼吸衰竭
第二篇 第十四章 呼吸衰竭第二篇 第十四章 呼吸衰竭
第二篇 第十四章 呼吸衰竭yansongfan
 
肝硬化病人之用藥調整 實證文獻回顧
肝硬化病人之用藥調整 實證文獻回顧肝硬化病人之用藥調整 實證文獻回顧
肝硬化病人之用藥調整 實證文獻回顧Ming Chia Lee
 
chapter4 Blood Circle
chapter4 Blood Circlechapter4 Blood Circle
chapter4 Blood CircleLuohe Medical College
 
高亮：神经重症患者的血压处理
高亮：神经重症患者的血压处理高亮：神经重症患者的血压处理
高亮：神经重症患者的血压处理neuroccm
 
2011心力衰竭本科麻醉1
2011心力衰竭本科麻醉12011心力衰竭本科麻醉1
2011心力衰竭本科麻醉1yansongfan
 
心梗并发症
心梗并发症心梗并发症
心梗并发症hong3323
 
Renal pharmacotherapy 1
Renal pharmacotherapy 1Renal pharmacotherapy 1
Renal pharmacotherapy 1Ming Chia Lee
 
Ekg
EkgEkg
Ekgguestf4e7d41
 
心衰竭需注意藥物
心衰竭需注意藥物心衰竭需注意藥物
心衰竭需注意藥物孫鴻 周
 
Arrhythmia News 007
Arrhythmia News 007Arrhythmia News 007
Arrhythmia News 007Taiwan Heart Rhythm Society
 
(老人用藥)Clonidine
(老人用藥)Clonidine(老人用藥)Clonidine
(老人用藥)Clonidine孫鴻 周
 
EKG 海大.pptx
EKG 海大.pptxEKG 海大.pptx
EKG 海大.pptxMingFengLi6
 
Hypertension in chinese
Hypertension in chineseHypertension in chinese
Hypertension in chineseKochi Chia
 
Arrhythmia News 005
Arrhythmia News 005Arrhythmia News 005
Arrhythmia News 005Taiwan Heart Rhythm Society
 
心瓣膜病（内科学）
心瓣膜病（内科学）心瓣膜病（内科学）
心瓣膜病（内科学）sameul_li
 
Chronic Venous Disease 下肢静脉功能不全简介
Chronic Venous Disease 下肢静脉功能不全简介Chronic Venous Disease 下肢静脉功能不全简介
Chronic Venous Disease 下肢静脉功能不全简介Lei Zhu
 
Arrhythmia News 003
Arrhythmia News 003Arrhythmia News 003
Arrhythmia News 003Taiwan Heart Rhythm Society
 
显微外科学习班幻灯
显微外科学习班幻灯显微外科学习班幻灯
显微外科学习班幻灯ebonenow
 
抗憂鬱劑中毒的治療1
抗憂鬱劑中毒的治療1抗憂鬱劑中毒的治療1
抗憂鬱劑中毒的治療1Ming Chia Lee
 
P rqѽ貧`
P rqѽ貧`P rqѽ貧`
P rqѽ貧`guest30cb787
 
Windows Xp DeskTop Background（XP桌面壁纸）
Windows Xp DeskTop Background（XP桌面壁纸）Windows Xp DeskTop Background（XP桌面壁纸）
Windows Xp DeskTop Background（XP桌面壁纸）laowantong
 
阳关三叠（Yang_Guan_San_Die）
阳关三叠（Yang_Guan_San_Die）阳关三叠（Yang_Guan_San_Die）
阳关三叠（Yang_Guan_San_Die）laowantong
 
Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'
Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'
Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'laowantong
 
Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）
Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）
Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）laowantong
 
About Wu-GuanZhong's 吴冠中简介
About Wu-GuanZhong's 吴冠中简介About Wu-GuanZhong's 吴冠中简介
About Wu-GuanZhong's 吴冠中简介laowantong
 

Weitere ähnliche Inhalte

Ähnlich wie 心血管药理

高亮：神经重症患者的血压处理
高亮：神经重症患者的血压处理高亮：神经重症患者的血压处理
高亮：神经重症患者的血压处理neuroccm
 
2011心力衰竭本科麻醉1
2011心力衰竭本科麻醉12011心力衰竭本科麻醉1
2011心力衰竭本科麻醉1yansongfan
 
心梗并发症
心梗并发症心梗并发症
心梗并发症hong3323
 
Renal pharmacotherapy 1
Renal pharmacotherapy 1Renal pharmacotherapy 1
Renal pharmacotherapy 1Ming Chia Lee
 
心衰竭需注意藥物
心衰竭需注意藥物心衰竭需注意藥物
心衰竭需注意藥物孫鴻 周
 
(老人用藥)Clonidine
(老人用藥)Clonidine(老人用藥)Clonidine
(老人用藥)Clonidine孫鴻 周
 
Hypertension in chinese
Hypertension in chineseHypertension in chinese
Hypertension in chineseKochi Chia
 
心瓣膜病（内科学）
心瓣膜病（内科学）心瓣膜病（内科学）
心瓣膜病（内科学）sameul_li
 
Chronic Venous Disease 下肢静脉功能不全简介
Chronic Venous Disease 下肢静脉功能不全简介Chronic Venous Disease 下肢静脉功能不全简介
Chronic Venous Disease 下肢静脉功能不全简介Lei Zhu
 
显微外科学习班幻灯
显微外科学习班幻灯显微外科学习班幻灯
显微外科学习班幻灯ebonenow
 
抗憂鬱劑中毒的治療1
抗憂鬱劑中毒的治療1抗憂鬱劑中毒的治療1
抗憂鬱劑中毒的治療1Ming Chia Lee
 

Ähnlich wie 心血管药理 (17)

高亮：神经重症患者的血压处理
高亮：神经重症患者的血压处理高亮：神经重症患者的血压处理
高亮：神经重症患者的血压处理
 
2011心力衰竭本科麻醉1
2011心力衰竭本科麻醉12011心力衰竭本科麻醉1
2011心力衰竭本科麻醉1
 
心梗并发症
心梗并发症心梗并发症
心梗并发症
 
Renal pharmacotherapy 1
Renal pharmacotherapy 1Renal pharmacotherapy 1
Renal pharmacotherapy 1
 
Ekg
EkgEkg
Ekg
 
心衰竭需注意藥物
心衰竭需注意藥物心衰竭需注意藥物
心衰竭需注意藥物
 
Arrhythmia News 007
Arrhythmia News 007Arrhythmia News 007
Arrhythmia News 007
 
(老人用藥)Clonidine
(老人用藥)Clonidine(老人用藥)Clonidine
(老人用藥)Clonidine
 
EKG 海大.pptx
EKG 海大.pptxEKG 海大.pptx
EKG 海大.pptx
 
Hypertension in chinese
Hypertension in chineseHypertension in chinese
Hypertension in chinese
 
Arrhythmia News 005
Arrhythmia News 005Arrhythmia News 005
Arrhythmia News 005
 
心瓣膜病（内科学）
心瓣膜病（内科学）心瓣膜病（内科学）
心瓣膜病（内科学）
 
Chronic Venous Disease 下肢静脉功能不全简介
Chronic Venous Disease 下肢静脉功能不全简介Chronic Venous Disease 下肢静脉功能不全简介
Chronic Venous Disease 下肢静脉功能不全简介
 
Arrhythmia News 003
Arrhythmia News 003Arrhythmia News 003
Arrhythmia News 003
 
显微外科学习班幻灯
显微外科学习班幻灯显微外科学习班幻灯
显微外科学习班幻灯
 
抗憂鬱劑中毒的治療1
抗憂鬱劑中毒的治療1抗憂鬱劑中毒的治療1
抗憂鬱劑中毒的治療1
 
P rqѽ貧`
P rqѽ貧`P rqѽ貧`
P rqѽ貧`
 

Mehr von laowantong

Windows Xp DeskTop Background（XP桌面壁纸）
Windows Xp DeskTop Background（XP桌面壁纸）Windows Xp DeskTop Background（XP桌面壁纸）
Windows Xp DeskTop Background（XP桌面壁纸）laowantong
 
阳关三叠（Yang_Guan_San_Die）
阳关三叠（Yang_Guan_San_Die）阳关三叠（Yang_Guan_San_Die）
阳关三叠（Yang_Guan_San_Die）laowantong
 
Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'
Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'
Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'laowantong
 
Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）
Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）
Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）laowantong
 
About Wu-GuanZhong's 吴冠中简介
About Wu-GuanZhong's 吴冠中简介About Wu-GuanZhong's 吴冠中简介
About Wu-GuanZhong's 吴冠中简介laowantong
 
Wu-GuanZhong's Paintings(3)《《耕耘与奉献》吴冠中捐赠作品选（之三）
Wu-GuanZhong's Paintings(3)《《耕耘与奉献》吴冠中捐赠作品选（之三）Wu-GuanZhong's Paintings(3)《《耕耘与奉献》吴冠中捐赠作品选（之三）
Wu-GuanZhong's Paintings(3)《《耕耘与奉献》吴冠中捐赠作品选（之三）laowantong
 
Wu-GuanZhong's Paintings(1)《耕耘与奉献》吴冠中捐赠作品选（之一）
Wu-GuanZhong's Paintings(1)《耕耘与奉献》吴冠中捐赠作品选（之一）Wu-GuanZhong's Paintings(1)《耕耘与奉献》吴冠中捐赠作品选（之一）
Wu-GuanZhong's Paintings(1)《耕耘与奉献》吴冠中捐赠作品选（之一）laowantong
 
Dubai（迪拜）
Dubai（迪拜）Dubai（迪拜）
Dubai（迪拜）laowantong
 
Leisurely and Comfortable（闲快活－国画·古词）
Leisurely and Comfortable（闲快活－国画·古词）Leisurely and Comfortable（闲快活－国画·古词）
Leisurely and Comfortable（闲快活－国画·古词）laowantong
 
Records in chungking,China,in 1940s（“陪都”重庆）
Records in chungking,China,in 1940s（“陪都”重庆）Records in chungking,China,in 1940s（“陪都”重庆）
Records in chungking,China,in 1940s（“陪都”重庆）laowantong
 
Beautiful Awarigul （阿瓦日古丽）G270
Beautiful Awarigul （阿瓦日古丽）G270Beautiful Awarigul （阿瓦日古丽）G270
Beautiful Awarigul （阿瓦日古丽）G270laowantong
 
Miss_World_2008 （2008 世界小姐）G228
Miss_World_2008 （2008 世界小姐）G228Miss_World_2008 （2008 世界小姐）G228
Miss_World_2008 （2008 世界小姐）G228laowantong
 
Body Painting （人体彩画）
Body Painting （人体彩画）Body Painting （人体彩画）
Body Painting （人体彩画）laowantong
 
Classical aesthetic painting （古典唯美的画作）
Classical aesthetic painting （古典唯美的画作）Classical aesthetic painting （古典唯美的画作）
Classical aesthetic painting （古典唯美的画作）laowantong
 
A beautiful town in china,after the snow ( 雪后周庒)
A beautiful town in china,after the snow ( 雪后周庒)A beautiful town in china,after the snow ( 雪后周庒)
A beautiful town in china,after the snow ( 雪后周庒)laowantong
 
中秋节快乐
中秋节快乐中秋节快乐
中秋节快乐laowantong
 
G203 精美绝伦的玻璃艺术
G203 精美绝伦的玻璃艺术G203 精美绝伦的玻璃艺术
G203 精美绝伦的玻璃艺术laowantong
 

Mehr von laowantong (17)

Windows Xp DeskTop Background（XP桌面壁纸）
Windows Xp DeskTop Background（XP桌面壁纸）Windows Xp DeskTop Background（XP桌面壁纸）
Windows Xp DeskTop Background（XP桌面壁纸）
 
阳关三叠（Yang_Guan_San_Die）
阳关三叠（Yang_Guan_San_Die）阳关三叠（Yang_Guan_San_Die）
阳关三叠（Yang_Guan_San_Die）
 
Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'
Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'
Our Old English Songs 'One day when we were young（南开中学教唱英文歌曲集）.pps'
 
Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）
Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）
Wu-GuanZhong's paintings《耕耘与奉献》吴冠中捐赠作品选（之二）
 
About Wu-GuanZhong's 吴冠中简介
About Wu-GuanZhong's 吴冠中简介About Wu-GuanZhong's 吴冠中简介
About Wu-GuanZhong's 吴冠中简介
 
Wu-GuanZhong's Paintings(3)《《耕耘与奉献》吴冠中捐赠作品选（之三）
Wu-GuanZhong's Paintings(3)《《耕耘与奉献》吴冠中捐赠作品选（之三）Wu-GuanZhong's Paintings(3)《《耕耘与奉献》吴冠中捐赠作品选（之三）
Wu-GuanZhong's Paintings(3)《《耕耘与奉献》吴冠中捐赠作品选（之三）
 
Wu-GuanZhong's Paintings(1)《耕耘与奉献》吴冠中捐赠作品选（之一）
Wu-GuanZhong's Paintings(1)《耕耘与奉献》吴冠中捐赠作品选（之一）Wu-GuanZhong's Paintings(1)《耕耘与奉献》吴冠中捐赠作品选（之一）
Wu-GuanZhong's Paintings(1)《耕耘与奉献》吴冠中捐赠作品选（之一）
 
Dubai（迪拜）
Dubai（迪拜）Dubai（迪拜）
Dubai（迪拜）
 
Leisurely and Comfortable（闲快活－国画·古词）
Leisurely and Comfortable（闲快活－国画·古词）Leisurely and Comfortable（闲快活－国画·古词）
Leisurely and Comfortable（闲快活－国画·古词）
 
Records in chungking,China,in 1940s（“陪都”重庆）
Records in chungking,China,in 1940s（“陪都”重庆）Records in chungking,China,in 1940s（“陪都”重庆）
Records in chungking,China,in 1940s（“陪都”重庆）
 
Beautiful Awarigul （阿瓦日古丽）G270
Beautiful Awarigul （阿瓦日古丽）G270Beautiful Awarigul （阿瓦日古丽）G270
Beautiful Awarigul （阿瓦日古丽）G270
 
Miss_World_2008 （2008 世界小姐）G228
Miss_World_2008 （2008 世界小姐）G228Miss_World_2008 （2008 世界小姐）G228
Miss_World_2008 （2008 世界小姐）G228
 
Body Painting （人体彩画）
Body Painting （人体彩画）Body Painting （人体彩画）
Body Painting （人体彩画）
 
Classical aesthetic painting （古典唯美的画作）
Classical aesthetic painting （古典唯美的画作）Classical aesthetic painting （古典唯美的画作）
Classical aesthetic painting （古典唯美的画作）
 
A beautiful town in china,after the snow ( 雪后周庒)
A beautiful town in china,after the snow ( 雪后周庒)A beautiful town in china,after the snow ( 雪后周庒)
A beautiful town in china,after the snow ( 雪后周庒)
 
中秋节快乐
中秋节快乐中秋节快乐
中秋节快乐
 
G203 精美绝伦的玻璃艺术
G203 精美绝伦的玻璃艺术G203 精美绝伦的玻璃艺术
G203 精美绝伦的玻璃艺术
 

心血管药理

  • 1. 心 血 管 药 理 (cardiovascular pharmacology) 刘俊田 82655188 （ O ） [email_address] office ： No.916 ， 9 th floor ， Library Building
  • 2. 第 24 章 作用于心血管系统离子通道的药物 ( drugs acting on ion channels in cardiovascular system )
  • 3.
  • 4.
  • 5.  
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.  
  • 20.
  • 21.  
  • 22.  
  • 23.
  • 24.  
  • 25.
  • 26.
  • 27.  
  • 28.
  • 29.  
  • 30.
  • 31.
  • 32. 折返激动（ reentry ）发生机制 正常心肌 单向传导阻滞 折返形成
  • 33.  
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.  
  • 39.
  • 40.
  • 41. 0mV -85mV 0 1 2 3 4 ADP ERP
  • 42.
  • 43.
  • 44.
  • 45. 0mV -85mV 0 1 2 3 4 ADP ERP
  • 46.
  • 47.
  • 48.
  • 49.
  • 50.
  • 51.
  • 52.
  • 53.
  • 54.
  • 55.
  • 56.
  • 57.
  • 58.
  • 59.
  • 60.  
  • 61. 概 论 1. 概述：心功能不全又称心力衰竭，是指在各种病理因素作用下心脏循环功能受损，导致心输出量不能满足机体的需要而产生的综合征。 2. 心功能不全发生的病理生理过程。* 3. 影响心功能的因素 : 心肌收缩性 , 心率 , 心脏前后负荷。 4. 心功能不全的分型及抗心功能不全药物的分类 (1) 急性心功能不全：镇痛药；强心药；血管扩张药；强效利尿药。 (2) 慢性心功能不全：强心药，血管扩张药，利尿药， ACEI ， β 受体阻断剂等。
  • 62.  
  • 63. 概 论 1. 概述：心功能不全又称心力衰竭，是指在各种病理因素作用下心脏循环功能受损，导致心输出量不能满足机体的需要而产生的综合征。 2. 心功能不全发生的病理生理过程。 3. 影响心功能的因素 : 心肌收缩性 , 心率 , 心脏前后负荷。 4. 药物治疗史： 洋地黄类->利尿药（ 50 年代）->血管扩张药（ 70 年代）->其他强心药（ 70 年代末）-> ACEI （ 80 年代）-> β 受体阻滞药（ 90 年代后期）-> AVP 受体拮抗药， ET 受体拮抗药等
  • 64.
  • 65.
  • 66. 顺应性↑ 血管紧张素Ⅱ ↓ 缓激肽 分解↓ 心室、主动脉 肥厚↓ 醛固酮分泌↓ 血容量↓ 血管扩张 血压 ↑ 激肽释放酶 肾素 血管紧张素原 激肽原 血管紧张素Ⅰ 缓激肽↑ PGI 2 ↑ PGE 2 ↑ EDHF ↑ NO ↑ 血管紧张素转化酶 ACEI ( 抑制 ) 血管扩张
  • 67.
  • 68.
  • 69.
  • 70.
  • 71.
  • 72.
  • 73.
  • 74.
  • 75.
  • 76.
  • 77.
  • 78.
  • 79.
  • 80.  
  • 81.
  • 82.
  • 83.  
  • 84.
  • 85.
  • 86.
  • 87.
  • 88.
  • 89.
  • 90.
  • 91.
  • 92.
  • 93.
  • 94.
  • 95.
  • 96.
  • 97.
  • 98.
  • 99.
  • 100.
  • 101.
  • 102.
  • 103.
  • 104.
  • 105.
  • 106.
  • 107.
  • 108.
  • 109.  
  • 110.  
  • 111.
  • 112.
  • 113.
  • 114.
  • 115.  
  • 116.
  • 117.
  • 118.
  • 119.
  • 120.
  • 121.
  • 122.
  • 123.
  • 124.
  • 125.
  • 126.
  • 127.
  • 128.
  • 129.
  • 130.
  • 131.
  • 132.
  • 133.
  • 134.
  • 135.
  • 136.
  • 137.
  • 138.
  • 139.  
  • 140.
  • 141.
  • 142.  
  • 143.
  • 144.
  • 145.
  • 146.
  • 147. 顺应性↑ 血管紧张素Ⅱ ↓ 缓激肽 分解↓ 心室、主动脉 肥厚↓ 醛固酮分泌↓ 血容量↓ 血管扩张 血压 ↑ 激肽释放酶 肾素 血管紧张素原 激肽原 血管紧张素Ⅰ 缓激肽↑ PGI 2 ↑ PGE 2 ↑ EDHF ↑ NO ↑ 血管紧张素转化酶 ACEI ( 抑制 ) 血管扩张
  • 148.  
  • 149.
  • 150.
  • 151.
  • 152.
  • 153.
  • 154.
  • 155.
  • 156.
  • 157.
  • 158.
  • 159.
  • 160.
  • 161.
  • 162.
  • 163.
  • 164.
  • 165.
  • 166.
  • 167.
  • 168.
  • 169.  
  • 170.
  • 171.
  • 172. Thanks for your cooperation ！

Hinweis der Redaktion

  1. 11111