XVI. Drug Study
NAME OF
MACHANISM OF
DOSAGE
INDICATIONS
CONTRA-
ADVERSE
NURSING ALERT
THE DRUG
Generic
ACTION
Thought to
Dosage:
Mild pain or
INDICATIONS
-Contra-
REACTION
-Hematologic:
-Use liquid form for children
Name:
produce
250/5ml
fever
indicated in
Hemolytic
and patients who difficulty
Paracetamol
analgesia by
patient
Anemia,
of swallowing.
blocking pain
Frequency:
hypersensitivity Leukopenia,
-In children don’t exceed
Brand
impulses by
q4h
to drug.
five (5) doses in 24h.
Name:
inhibiting
Tempra
synthesis of
Classification:
in patients with
-Hepatic:
only for short-term use;
prostaglandin in
Non opioids
long-term
Jaundice
urge them to consult
the CNS or of
analgesics and
alcohol use of
other substances
antipyretics
alcohol
-Metabolic:
children for longer than 5
that sensitize pain
because
hypoglycemia
days or adults for longer
receptors to
therapeutic
stimulation. The
doses cause
-Skin: rash,
-Tell parents/patient not to
drug may relieve
hepatotoxicity
urticaria
use for marked fever (temp
fever through
in these
higher than 103.1F or
central action in
patients.
39.5C), fever persisting
Neutropenia,
-Use cautiously
-Advise parents that drug is
prescriber if giving to
than 10 days.
the hypothalamic
longer than 3 days, or
heat-regulating
recurrent fever unless
center.
directed by prescriber.
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NAME OF
MECHANISM
DOSAGE
INDICATIONS
CONTRA-
ADVERSE
NURSING ALERT

THE DRUG
OF ACTION
INDICATIONS
REACTION
Generic
Second-
Dosage:
-Serious lower
-Contraindicated
-GI: diarrhea,
-Before giving drug,
Name:
generation
500mg
respiratory tract
in patient with
nausea,
ask patient/parents if
Cefuroxime
cephalosporin
infection, UTI,
hypersensitivity to
anorexia,
he is allergic to
Sodium
that inhibits
Frequency:
skin structure
drug or other
vomiting
penicillins or
cell- wall
q8h
infections
cephalosporin.
-Hematologic:
cephalosporin.
-Use cautiously in
hemolytic
-Obtain specimen for
Brand
synthesis,
Name:
promoting
Classification:
patient
anemia,
C/S test before giving
Zinacef
osmotic
Second
hypersensitivity to
thrombocytopeni
first dose.
instability,
generation
penicillin because
a, eosinophilia
-Tablets may be
usually
Cephalosporin
of possibility of
-Skin:
crushed, if absolutely
cross sensitivity
maculopapular
necessary, for patient
with other beta-
and
who can’t swallow
lactam antibiotics.
erythematous
tablets. Tablets can be
.
rashes, urticarial,
dissolved in juices,
pain,
chocolate or milk,
temperature
however, the drug has
elevation,
a bitter taste that is
anaphylaxis,
difficult to mask, even
hypersensitivity
with food.
reaction
-Don’t confuse drug
bactericidal.
25
with other
cephalosporins that

sound alike.
-Tell patient to take
drug as prescribed,
even after he feels
better.
-Instruct patient to take
oral form with food.
-Instruct patient to
notify prescriber about
rash, loose stool,
diarrhea or evidence of
superinfection.

Contraindicated in patient with hypersensitivity to drug or other cephalosporin.
-Use cautiously in patient hypersensitivity to penicillin because of possibility of cross sensitivity with other beta- lactam
antibiotics.
.
-CV: phlebitis, thrombophlebitis
-GI: diarrhea, nausea, anorexia, vomiting
-Hematologic: hemolytic anemia, thrombocytopenia, eosinophilia
-Skin: maculopapular and erythematous rashes, urticarial, pain, sterile abcesses, temperature elevation, anaphylaxis,
hypersensitivity reaction
-Before giving drug, ask patient/parents if he is allergic to penicillins or cephalosporin.
-Obtain specimen for C/S test before giving first dose.
-For IM use, inject deep into a large muscle, such as gluteus maximus or the side of the thigh.
-Absorption of oral drug is enhanced by food.
-Tablets may be crushed, if absolutely necessary, for patient who can’t swallow tablets. Tablets can be dissolved in juices,
chocolate or milk, however, the drug has a bitter taste that is difficult to mask, even with food.
-Don’t confuse drug with other cephalosporins that sound alike.
-Tell patient to take drug as prescribed, even after he feels better.
-Instruct patient to take oral form with food.
-Instruct patient to notify prescriber about rash, loose stool, diarrhea or evidence of superinfection.
26

Contraindicated in patient with hypersensitivity to drug or other cephalosporin.
-Use cautiously in patient hypersensitivity to penicillin because of possibility of cross sensitivity with other beta- lactam
antibiotics.
.
-CV: phlebitis, thrombophlebitis
-GI: diarrhea, nausea, anorexia, vomiting
-Hematologic: hemolytic anemia, thrombocytopenia, eosinophilia
-Skin: maculopapular and erythematous rashes, urticarial, pain, sterile abcesses, temperature elevation, anaphylaxis,
hypersensitivity reaction
-Before giving drug, ask patient/parents if he is allergic to penicillins or cephalosporin.
-Obtain specimen for C/S test before giving first dose.
-For IM use, inject deep into a large muscle, such as gluteus maximus or the side of the thigh.
-Absorption of oral drug is enhanced by food.
-Tablets may be crushed, if absolutely necessary, for patient who can’t swallow tablets. Tablets can be dissolved in juices,
chocolate or milk, however, the drug has a bitter taste that is difficult to mask, even with food.
-Don’t confuse drug with other cephalosporins that sound alike.
-Tell patient to take drug as prescribed, even after he feels better.
-Instruct patient to take oral form with food.
-Instruct patient to notify prescriber about rash, loose stool, diarrhea or evidence of superinfection.
26