The document discusses how it was previously thought that nervous tissue growth only occurred in youth, but recent evidence suggests it also occurs in adults. Brain-derived neurotrophic factor (BDNF) was first isolated from pig brains in 1982 and is similar to nerve growth factor. Studies in mice and humans have found that aerobic exercise increases BDNF levels and hippocampal volume, suggesting exercise may promote neurogenesis in adults.

2. “The growth and development of
Nervous tissue”
 Used to be thought that it only occurred
in youth
 Recent evidence strongly suggests it
does occur in adults as well


3. „I please‟
 Simulated/medically ineffectual
treatment for a disease or other medical
condition intended to deceive the
recipient


4. Brain-Derived
Neurotrophic Factor
 First isolated – Pig
brains, 1982 (Barde et
al.)
 Similar to Nerve
growth factor


5. 1998 – running increases BDNF levels in
the hippocampus of mice
 1999 – mice running increases cell
proliferation in part of hippocampus


6. In Humans:
 2010 (Kramer et al.)– Aerobic exercise
increases hippocampal volume by
about 2% in 1-2 years


7. 


Help memory formation of how food was hunted or
predators were escaped
And/or
Cell proliferation – uses lots of energy; Promise of
energy replacement from food

11. Associated with Long-term
Potentiation (a mechanism for
memory formation)

12. Offset
 Neurodegenerative
 diseases!


13. 
NEUROGENESIS COUNTERS
NEURODEGENERATION!