Cardiovascular disease is the leading cause of death in the US, affecting over 81 million Americans. Some key facts presented are that smoking, high blood pressure, high cholesterol, physical inactivity, obesity, and diabetes are major controllable risk factors for cardiovascular disease. The document also outlines the anatomy and function of the heart and blood vessels, signs and symptoms of common cardiovascular conditions like heart attack and stroke, diagnostic tests and treatments used, and lifestyle modifications that can reduce risk of cardiovascular disease.