2. Interphase; At this time, the cells may look inactive, but they are quite the opposite. This is the longest stage of the cell cycle when DNA is copied, the centriolesdivide, and the proteins are produced.
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8. Prophase; At this stage, the nucleolus disappears, and the copied DNA and proteins (chromatin) are condensed into chromosomes. Each copied chromosome is made of 2 chromatids, both with the same genetic information.
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12. Prometaphase; In this stage, you can no longer recognize the nucleus. Some of the mitotic spindle fibres become longer from the centrosomes and attach to the knetochores, the protein bundles at the centromere region on the chromosomes where the sister chromatidsare joined. While the other spindle fibres become longer but instead of attaching to the chromosomes, they overlap each other at the cell center.
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14. Metaphase; The tension applied by the spindle fibres puts all the chromosomes aligned in the center of the cell.
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17. Anaphase; Spindle fibres shorten, the kinetochores separate, and the daughter chromosomes (chromatids) are then pulled apart and begin moving to the cell poles.
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20. Telophase; The chromatids (daughter chromosomes) arrive at the pole and the spindle fibres that pulled them apart disappear.
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24. Cytokinesis; The spindle fibres that aren’t attached to the chromosomes start to break down until only a part of overlap is left. It is in this region that a contractile ring leaves the cell into the 2 daughter cells (chromatids). Microtubes then reorganize into a new cytoskeleton, and then return to interphase.
