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Scientific Highlights: The Reflect and NetPhorest web resources

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Lars Juhl Jensen
Lars Juhl Jensen

Novo Nordisk Foundation Center for Protein Research Scientific Advisory Board Meeting, Hvidøre, Klampenborg, Denmark, May 15, 2009

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Scientific Highlights The Reflect and NetPhorest web resources www.cpr.ku.dk Lars Juhl Jensen [email_address]
Reflect
real-time text mining
enhance text with data
 
augmented browsing
 
 
collaborate publishers
user editing
more dictionaries
taxonomy
diseases
mutations
protein modifications
NetPhorest
sequence motifs
 
automated pipeline
Miller, Jensen et al., Science Signaling , 2008
data organization
Miller, Jensen et al., Science Signaling , 2008
compilation of datasets
redundancy reduction
training and evaluation
classifier selection
motif collection
179 kinases
93 SH2 domains
8 PTB domains
BRCT domains
WW domains
14-3-3 proteins
23 phosphatases
F-box proteins
other modifications
model organisms
S. cerevisiae
D. melanogaster
C. elegans
use cases
disease-related kinases
Miller, Jensen et al., Science Signaling , 2008
cell-cycle kinases
 
human variation
signaling networks
NetworKIN
Linding, Jensen, Ostheimer et al., Cell , 2007
experiment design
Fedorov et al., PNAS , 2007
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