1. Plymouth, MI 48170
Phone (734) 737-0532
Karen Sanders
Objective Chemist
Education Win. 2009-June 2010 Eastern Michigan University Ypsilanti, MI
Master of Science
• Master’s level chemistry coursework and research experience.
Fall 2002-Fall 2008 Eastern Michigan University Ypsilanti, MI
Bachelor of Science (Dual Major)
• Professional Chemistry with American Chemical Society
Certification
• History Major/Biology Minor
• Honors College Graduate
• Winter 2008: “Outstanding Accomplishment in Chemistry Award”
1999-2001 Oakland Community College Farmington Hills, MI
• Applied Science
Experience June 2008-Dec. 2009 Eastern Michigan University Ypsilanti, MI
Research Chemist
• Primary research focuses on the synthesis of a Plasminogen
Activator Inhibitor-1 (PAI-1) inhibitory molecule.
• Earned 16 research credit hours consisting of 30-40 hours of
laboratory work per week over the course of two years.
Aug. 2002- Aug. 2005 Stanton and Associates Belleville, MI
Assistant Manager
• Serve Safe Certified
• Implemented scheduling for 40 plus staff.
• Trained new employees including shift managers.
• Implemented profit and loss statements and ordered store supplies.
Software Beilstein, Cambridge’s Chem-draw, Sci-finder, Wavefunction’s Spartan, Excel,
Word, Access, PowerPoint, Graphical Analysis, and Refworks.
Publications and Coauthor on an in-progress research article that will be submitted to a high-
Presentations impact peer reviewed chemistry journal within 4 months. The article concerns
the design, synthesis, and assessment of PAI-1 inhibitors.
Characterization of a Novel Class of Polyphenolic Inhibitors of
Plasminogen Activator Inhibitor-1 Jacqueline M. Cale1‡, Shih-Hon Li1‡, Mark
Warnock1, Enming J. Su1, Paul R. North2, Karen L. Sanders2, Maria M.
Puscau2, Cory D. Emal2, and Daniel A. Lawrence1 2010 J. Bio. Chem. 285 (11)

2. 7892-7902.
1
Department of Internal Medicine, Division of Cardiovascular Medicine,
University of Michigan Medical School, 7301 MSRB III, 1150 W. Medical
Center Drive, Ann Arbor MI, 48109-0644, and 2Department of Chemistry, 225
Mark Jefferson, Eastern Michigan University, Ypsilanti, MI 48197.
2010 National Meeting and Exposition of the American Chemical Society
San Francisco, CA – 03/24/10
Structure-Activity Relationships of Sulfonamide and Ester-Based
Inhibitors of Plasminogen Activator Inhibitor-1.
Karen L. Sanders, Nadine C. El-Ayache, Gregory A. Abernathy1, Melinda S.
Meyers1, Paul R. North1, Shih-Hon Li2, Mark Warnock2, Daniel A. Lawrence2,
Cory D. Emal1. 1 Chemistry Department, Eastern Michigan University,
Ypsilanti, MI 48197. 2 Department of Internal Medicine, University of
Michigan Medical School, Ann Arbor, MI 48109-0644.
2010 Eastern Michigan University Graduate Symposium
Ypsilanti, MI – 03/24/10
Examination of the Structure-Activity Relationships of Inhibitors of
Plasminogen Activator Inhibitor-1.
Karen L. Sanders1, Hasina Saraha1, Mark Warnock2, Daniel A. Lawrence2,
Cory D. Emal1. 1 Chemistry Department, Eastern Michigan University,
Ypsilanti, MI 48197. 2 Department of Internal Medicine, University of
Michigan Medical School, Ann Arbor, MI 48109-0644.
2009 Eastern Michigan University Symposium
Ypsilanti, MI – 03/27/09
Design, Synthesis, and Evaluation of Polyphenolic Inhibitors of
Plasminogen Activator Inhibitor-1.
Karen L. Sanders1, Kristi L. Henricks1, Melinda Meyers1, Mark Warnock2,
Daniel A. Lawrence2, Cory D. Emal1. 1 Chemistry Department, Eastern
Michigan University, Ypsilanti, MI 48197. 2 Department of Internal Medicine,
University of Michigan Medical School, Ann Arbor, MI 48109-0644.
Sanders, Karen. “Sustainable Trade in Pre-Colonial Asante” (Senior Thesis).
Eastern Michigan University Honors College. 2008.
Interests Skydiving, culinary arts, astronomy, and traveling.
Working Knowledge of the following Instruments and Organic Synthesis Techniques
`Jeol 400 MHz 1H/13C NMR spectrometer, Shimadzu FTIR 84005, Varian Saturn 3800-2000
GC/MS, Buck HPLC, Buck 210 AAS, Schimadzu GC-14 with FID, Rotavapor R-3000, recrystallization,
column chromatography, flash chromatography, and thin-layer chromatography. I also have a limited
working knowledge of the following: Jasco FP-6300 Spectroflurometer, SMDE model 303A differential
pulse polarography, Perkin-Elmer Lambda UV-VIS, Cary 83 laser-Raman spectrophotometer, calorimetry,
gravimetry, and coulometry.
My research has utilized several organic reaction techniques including the following: Suzuki
coupling, hydrogenation, hydrolysis, esterification, and the placement and removal of various protective
groups including benzyl, methyl, and Boc groups. On a more mechanical note I have also had experience
building a Schlenk line and setting up distillation, vacuum distillation, condensation, and reflux apparatus
and would look forward to assisting in the development of a research laboratory from scratch.