1. Banned Medicines Still Selling In India
Here are some of the Drugs that have been globally discarded but are available in Indian
markets:
Analgin
It is a painkiller
Reason for ban: Bone marrow depression.
Brand name: Novalgin
Cisapride
For acidity, constipation
Reason for ban: Irregular heartbeat
Brand name: Ciza, Syspride
Droperidol
Anti-depressant. Reason for ban : Irregular heartbeat.
Brand name: Droperol
Furazolidone
Anti-diarrhoeal
Reason for ban: Cancer
Brand name: Furoxone, Lomofen
Nimesulide
Painkiller, fever
Reason for ban: Liver failure
Brand name: Nise, Nimulid
Nitrofurazone
Anti-bacterial cream
Reason for ban: Cancer
Brand name: Furacin
Phenolphthalein
Laxative
Reason for ban: Cancer
Brand name: Agarol
Phenylpropanolamine
Cold and cough
Reason for ban: stroke
Brand name: D’cold, Vicks Action – 500

2. Oxyphenbutazone
Non-steroidal anti-inflammatory drug
Reason for ban: Bone marrow depression
Brand name : Sioril
Piperazine
Anti-worms
Reason for ban: Nerve damage
Brand name: Piperazine
Quiniodochlor
Anti-diarrhoeal
Reason for ban: Damage to sight
Brand name: Enteroquinol
Tegaserod
Tegaserod is a drug that is used to treat patients with irritable bowel syndrome with
predominantly constipation. It was withdrawn from the market since patients taking this drug
showed increased incidence of heart attack and stroke.
Human Placental extract
Human placental extract is used in the cosmetic industry in the form of lotion, gel and
injection. It is not permitted in some countries since it can transmit diseases to the user. It is
under the scanner and may be banned in the future.
Thioridazine
Thioridazine is an antipsychotic drug. It causes adverse effects like arrhythmia (abnormal
heart rhythm), eye damage, and a condition called neuroleptic malignant syndrome.
Read more: http://www.funonthenet.in/forums/index.php?topic=208345.0#ixzz2KDlMoVhE
Vicks Action 500 is the brand name of a combination medicine that contains:
paracetamol 500 mg + phenylpropanolamine (PPA) 25 mg + caffeine 32 mg per tablet.
Paracetamol is a pain-killer while PPA is a decongestant. Caffeine is added to
counteract the sedative side effect of PPA. Vicks Action 500 is not a very safe medicine
because one of its ingredients (PPA) is banned in nearly all European and North
American countries. PPA has been implicated in causation of stroke - a potentially
dangerous and life-threatening side effect. Unfortunately the Indian drug control
systemdue to a variety of non-scientific reasons has not banned the use of PPA in
India.
(Source: doctor.ndtv.com)

3. Read more: http://www.funonthenet.in/forums/index.php?topic=208345.0#ixzz2KDmCNfa0
Drugs Prohibited from the date of Notification
1. Amidopyrine.
2. Fixed dose combinations of vitamins with anti–inflammatory agents and tranquilizers.
3. Fixed dose combinations of Atropine in Analgesics and Antipyretics.
4. Fixed dose combinations of Strychnine and Caffeine in tonics.
5. Fixed dose combinations of Yohimbine and Strychnine with Testosterone and Vitamins.
6. Fixed dose combinations of Iron with Strychnine, Arsenic and Yohimbine.
7. Fixed dose combinations of Sodium Bromide/chloral hydrate with other drugs.
8. Phenacetin.
9. Fixed dose combinations of antihistaminic with anti-diarrhoeals.
10. Fixed dose combinations of Penicillin with Sulphonamides.
11. Fixed dose combinations of Vitamins with Analgesics.
12. Fixed dose combinations of any other Tetracycline with Vitamin C.
13. Fixed dose combinations of Hydroxyquinoline group of drugs with any other drug except
for preparations meant for external use.
14. Fixed dose combinations of Corticosteroids with any other drug for internal use.
15. Fixed dose combinations of Chloramphenicol with any other drug for internal use.
16. Fixed dose combinations of crude Ergot preparations except those containing Ergotamine,
Caffeine, analgesics, antihistamines for the treatment of migraine, headaches.
17. Fixed dose combinations of Vitamins with Anti TB drugs except combination of Isoniazid
with Pyridoxine Hydrochloride (Vitamin B6).
18. Penicillin skin/eye Ointment.
19. Tetracycline Liquid Oral preparations.
20. Nialamide.
21. Practolol.
22. Methapyrilene, its salts.
23. Methaqualone.
24. Oxytetracycline Liquid Oral preparations.
25. Demeclocycline Liquid Oral preparations.
26. Combination of anabolic Steroids with other drugs.
27. Fixed dose combination of Oestrogen and Progestin (other than oral contraceptive)
containing per tablet estrogen content of more than 50 mcg (equivalent to Ethinyl
Estradiol) and progestin content of more than 3 mg (equivalent to Norethisterone Acetate)
and all fixed dose combination injectable preparations containing synthetic Oestrogen and
Progesterone. (Subs. By Noti. No. 743 (E) dt 10-08-1989)
28. Fixed dose combination of Sedatives/ hypnotics/anxiolytics with analgesics-antipyretics.

4. 29. Fixed dose combination of Rifanpicin, isoniazid and Pyrazinamide, except those which
provide daily adult dose given below:
Drugs Minimum Maximum
Rifampicin 450 mg 600 mg
Isoniazid 300 mg 400 mg
Pyrazinamide 1000mg 1500 mg
30. Fixed dose combination of Histamine H-2 receptor antagonists with antacids except for
those combinations approved by Drugs Controller, India.
31. The patent and proprietary medicines of fixed dose combinations of essential oils with
alcohol having percentage higher than 20% proof except preparations given in the Indian
Pharmacopoeia.
32. All Pharmaceutical preparations containing Chloroform exceeding 0.5% w/w or v/v
whichever is appropriate.
33. Fixed dose combination of Ethambutol with INH other than the following: INH
Ethambutol 200 mg. 600 mg. 300 mg. 800 mg.
34. Fixed dose combination containing more than one antihistamine.
35. Fixed dose combination of any anthelmintic with cathartic/purgative except for
piperazine/Santonim.
36. Fixed dose combination of Salbutamol or any other bronchodilator with centrally acting
anti-tussive and/or antihistamine.
37. Fixed dose combination of laxatives and/or anti-spasmodic drugs in enzyme preparations.
38. Fixed dose combination of Metoclopramide with systemically absorbed drugs except
fixed dose combination of metoclopramide with aspirin/paracetamol
39. Fixed dose combination of centrally acting, antitussive with antihistamine, having high
atropine like activity in expectorants.
40. Preparations claiming to combat cough associated with asthma containing centrally acting
antitussive and/ or an antihistamine.
41. Liquid oral tonic preparations containing glycerophosphates and/or other phosphates and /
or central nervous system stimulant and such preparations containing alcohol more than
20% proof.
42. Fixed dose combination containing Pectin and/or Kaolin with any drug which is
systemically absorbed from GI tract except for combinations of Pectin and/or Kaolin with
drugs not systemically absorbed.
43. Chloral Hydrate as a drug.
44. Dovers Powder I.P.
45. Dover’s Powder Tablets I.P.
46. Antidiarrhoeal formulations containing Kaolin or Pectin or Attapulgite or Activated
Charcoal.

5. 47. Antidiarrhoeal formulations containing Phthalyl Sulphathiazole or Sulphaguanidine or
Succinyl Sulphathiazole.
48. Antidiarrhoeal formulations containing Neomycin or Streptomycin or
Dihydrostreptomycin including their respective salts or esters.
49. Liquid Oral antidiarrhoeals or any other dosage form for pediatric use containing
Diphenoxylate Lorloperamide or Atropine or Belladona including their salts or esters or
metabolites Hyoscyamine or their extracts or their alkaloids.
50. Liquid Oral antidiarrhoeals or any other dosage form for pediatric use containing
halogenated hydroxyquinolines.
51. Fixed dose combination of antidiarrhoeals with electrolytes.
52. Patent and Proprietary Oral Rehydration Salts other than those conforming to the
53. Fixed dose combination of Oxyphenbutazone or Phenylbutazone with any other drug.
54. Fixed dose combination of Analgin with any other drug.
55. Fixed dose combination of dextropropoxyphene with any other drug other than anti-
spasmodics and/or non-steriodal anti-inflammatory drugs (NSAIDS).
56. Fixed dose combination of a drug, standards of which are prescribed in the Second
Schedule to the said Act with an Ayurvedic, Siddha or Unani drug.
57. Mepacrine Hydrochloride (Quinacrine and its salts) in any dosage form for use for female
sterilization or contraception.
58. Fenfluramine and Dexfenfluramine.
59. Fixed dose combination of Diazepam and Diphenhydramine Hydrochloride.
60. Rimonabant.
61. Rosiglitazone
62. Nimesulide formulations for human use in children below 12 years of age.
63. Cisapride and its formulations for human use.
64. Phenylpropanolamine and its formulation for human use.
65. Human Placental Extract and its formulations for human use.
66. Sibutramine and its formulations for human use, and
67. R-Sibutramine and its formulations for human use.
68. Gatifloxacin formulation for systemic use in human by any route including oral and
injectable
69. Tegaserod and its formulation for human use.
Why they are banned?
Drug No. 61
Rosiglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. It works as an
insulinsensitizer, by binding to the PPAR receptors in fat cells and making the cells more
responsivetoinsulin.

6. The main reason behind banning this drug was associated with a significantly increased risk
ofheartattack.
A meta-analysis of observational studies released in March, 2011 provides more evidence
that rosiglitazone is associated with a higher risk of heart failure, myocardial infarction (MI)
and death.
Datta Nirmal
Pune
Top

Fri, 2011-10-07 15:12
#2
Anonymous
Nimesulide formulations for human use in children below 12 years
Some common side effects linked with Nimesulide use are nausea, vomiting, diarrhea,
pruritis, skin rashes, headaches and dizziness. Some serious side effects when used in
newborns are renal failure and hepatic failure.
According to International Society of Drug Bulletins (ISDB), this non-steroidal anti-
inflammatory drug (NSAID) offers no therapeutic advantage or better gastrointestinal safety
compared with other NSAIDs, whereas it exposes patients to a higher risk of fatal hepatic
disorders.
Nimesulide has been drawn aside from the pharmaceitical market because of its hepatic
effects (risk of hepatatoxicity) on patients.
Mahendra singh
from Panjab University, Chandigarh
Top

Thu, 2011-10-06 23:46
#3
Anonymous
no. 32/
In high amount chloroform can be carcinogenic and also have severe harmful effect on CNS
Top

Thu, 2011-10-06 23:27
#4

7. Anonymous
Drug Number 60 / Rimonabant
Rimonabant is anorectic antiobesity drug. It is -1 agonist for the cannabinoid receptor CB1.
Shortly after market introduction, press reports and independent studies suggested side effects
occurred more intensely and more commonly than shown by the manufacturer in their
clinical studies. Resulting from drug actions at CB1 receptors in the brain, reports of severe
depression and suicidal thoughts are frequent.
AND IT IS WITHDRWN FROM THE MARKET.
Top

Thu, 2011-10-06 23:19
#5
Anonymous
No. 66 / Sibutramine and its formulations for human
Hello,
Good evening
Sibutramine is a centrally-acting serotonin-norepinephrine reuptake inhibitor structurally
related to amphetamines.
Sibutramine can substantially increase blood pressure and pulse in some patients. In 2010 the
FDA noted the concerns that sibutramine increases the risk of heart attacks and strokes in
patients with a history of cardiovascular disease.
Sibutramine has been associated with increased cardiovascular events and strokes and has
been withdrawn from the market in countries and regions including Australia, Canada, China,
the European Union, Hong Kong, India, Mexico, Thailand, the UK and the United States.
---
Kamal Patel
Manipal
Top

Thu, 2011-10-06 23:10
#6
Anonymous
No. 68 / GATIFLOXACIN
Hi, I am Karan Mistry

8. A Canadian study published in the New England Journal of Medicine in March 2006 claims
Tequin {brand name of gatifloxacin} can have "life threatening" side effects including
serious diabetes.
Other serious side effects reported with gatifloxacin include hallucinations, liver damage and
purpura. Union Health and Family Welfare Ministry of India on 18 march 2011 banned the
manufacture, sale and distribution of Gatifloxacin as it caused certain adverse side effects
Top

Mon, 2011-10-10 00:18
#7
Anonymous
its at serial no. 68
68
Top

Thu, 2011-10-06 16:31
#8
Anonymous
no. 20 / Nialamide
Nialamide is an irreversible and non-selective monoamine oxidase inhibitor
Banned May be due to extreme side effects: euphoria, psychomotor agitation, insomnia,
anxiety, headache, vertigo, tremor, hyperreflexia, manic state, or turnig a depression into
mania in bipolar disorder. Other side effects are arterial hypotension, orthostatic hypotension,
arterial hypertension, palpitations, hyperhidrosis, dry mouth, nausea, vomiting, epigastric
pain, constipation, vision problems, retrobulbar optic neuritis, polyneuritis, weight gain, acute
cardiac insufficiency, tachycardia, peripheral neuropathy, jaundice, hepatomegaly,
hyperbilirubinemia, urinary retention, elevated transaminases, cutaneous eruptions,
impotence, and delayed ejaculation.
Dangerous side effects are drug-induced hepatitis and hepatocellular insufficiency.
Top

Thu, 2011-10-06 16:24
#9
Anonymous
no.3 / Fixed dose combinations of Atropine in Analgesics..

9. Anticholinergic agents may delay and/or decrease the gastrointestinal absorption of
acetaminophen by reducing gastric motility and delaying gastric emptying. However, the
clinical relevance is probably minimal.
Top

Thu, 2011-10-06 15:52
#10
Anonymous
No . 54 / Analgin
Analgin known to cause agranulocytosis , widely used in Indian mmarket....
Top

Thu, 2011-10-06 15:32
#11
Anonymous
no-10 / Fixed dose combinations of Penicillin with Sulphonamide
Bacterial resistance is the main reason behind banning penicillin and sulphonamide
combination.
Top

Thu, 2011-10-06 15:25
#12
Anonymous
DRUG No. 21 / PRACTOLOL
Practolol is selective beta blocker and structurally similar as propanolol but it is banned
because of toxic effect.
* practolol disaster is considered the worst medical blunders since thalidomide.
It may cause oculomucocutaneous syndrome which is a severe syndrome whose signs include
conjunctivitis sicca and psoriasiform rashes, otitis and sclerosing serositis.
- Rohit Pagare
GLOBALLY BANNED MEDICINES STILL USING IN INDIA WHY ?
Banned drugs are flourishing through Indian markets lets look some of
the banned drugs which is highly used by most of Indians. Some medicines are even
prescribed by doctors. Self medication is the other threat among peoples

10. as just a simple cold or some pain comes most of the affected ones goes to medical
stores or nearby pharmacy and purchase some
drugs not knowing these simple symptoms are the part of big picture.
Lets stop self medication and put a habit of visiting hospital so to make a
better healthy habits .let look some of the mostly used drugs in Indian markets and
their side effects which after reading should shock most of us. These drugs are banne
d globally then why it is selling in India it’s a
big irony as authorities should do very stern action against as these medicines usually
cause death of the users.
Analgin
Mostly commonly used as a Pain killer
Reason of ban is bone marrow depression
Famous brand name novalgin.
Cisapride
Mostly used for acidity, constipation.
Reason for ban is irregular heart beat
Some brands like ciza, syspride is commonly used.
Phenolphthalein
Mainly used as laxative reason for ban is this medicine cause’s cancer
Some famous brand name agarol
DROPERIDOL:
Used mainly as Anti-depressant. Reason for ban: Irregular heartbeat.
Brand name: Droperol
FURAZOLIDONE:
Used as antidiarrhoeal. Reason for ban: Cancer.
Brand name: Furoxone, Lomofen
NIMESULIDE:
Used as Painkiller, fever. Reason for ban: Liver failure.
Brand name: Nise, Nimulid
NITROFURAZONE:
Used mainly as Antibacterial cream. Reason for ban: Cancer.
Brand name: Furacin
PHENYLPROPANOLAMINE:

11. Used as Cold and cough. Reason for ban: stroke.
Brand name: D'cold, Vicks Action-500
OXYPHENBUTAZONE:
Used as Non-steroidal anti-inflammatory drug. Reason for ban: Bone marrow depression.
Brand name: Sioril
PIPERAZINE:
Used as Anti-worms. Reason for ban: Nerve damage.
Brand name: Piperazine
QUINIODOCHLOR:
Used as Anti-diarrhoeal. Reason for ban: Damage to sight.
Brand name: Enteroquinol
DANGEROUS DRUGS:
THESE DRUGS HAVE BEEN GLOBALLY DISCARDED BUT ARE AVAILABLE IN
INDIA.
The most common ones are D cold, action 500 & Nimulid so if you have any
symptoms do not take these medicines and also to do not give your dear and near
ones as it may cause serious issues like stroke and even death visit your nearest GP.