The document discusses challenges with moving mission critical applications to the cloud. It describes how traditional "lift and shift" migrations can result in issues meeting SLAs, long recovery times, gaps in monitoring, and other problems due to a lack of optimization for the cloud. The panelists from GE Capital and McGraw-Hill Education discuss their experiences with key business challenges like organizational change and technical challenges including replacing load balancers and issues with proprietary software in the cloud. The document advocates adopting cloud-native architectures and DevOps practices to better align applications with cloud capabilities and automate deployments.