Complete report is available @ http://www.reportsnreports.com/reports/239426-outsourced-ion-channel-testing-trends-2013.html . • The main objectives were to comprehensively document current use of and potential interest in outsourcing ion channel primary screening, selectivity profiling and safety liability testing. The survey also investigated access to and future purchasing of stably transfected ion channel cell lines. • Equal emphasis was given to soliciting opinion from Pharma, Biotech and Academic Research segments, mainly in North America and Europe. • The survey looked at the following aspects of outsourced ion channel testing, as practiced to date (2013) and in some cases as predicted for the future (2015): current targeting of ion channels as therapeutic targets using primary screening; number of on-going screening programs with ion channels as a therapeutic target

1. Outsourced Ion Channel Testing Trends 2013
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2. Outsourced Ion Channel Testing Trends 2013
Executive Summary
This market report summarizes the results of HTStec’s industry-wide global web-based
benchmarking survey on outsourced ion channel testing carried out in April 2013.
The study was initiated by HTStec as part of its ongoing tracking of emerging life science
marketplaces. The questionnaire was compiled to meet the needs and interests of the
outsourced ion channel testing provider community.
The main objectives were to comprehensively document current use of and potential
interest in outsourcing ion channel primary screening, selectivity profiling and safety
liability testing. The survey also investigated access to and future purchasing of stably
transfected ion channel cell lines.
Equal emphasis was given to soliciting opinion from Pharma, Biotech and Academic
Research segments, mainly in North America and Europe.
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sales@reportsandreports.com with your contact details and questions if any.
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3. Outsourced Ion Channel Testing Trends 2013
The survey questionnaire consisted of 32 mainly multi-choice questions. In addition,
there were 6 questions related solely to survey demographics.
The survey collected 88 validated responses, of these 74% provided comprehensive input.
Survey responses were geographically split: 50% North America; 38% Europe; 9% Asia
(excluding Japan); and 3% Japan.
Survey respondents were drawn from persons or groups actively using or interested in
using outsourced ion channel primary screening, selectivity profiling and safety liability
testing.
Respondents came from: 19 Universities; 18 Large Pharma; 12 Biotech Companies; 12
Hospitals/Clinics/ Medical Schools; 11 Medium-Small Pharma; 6 Government Labs; 4
Research Institutes; 4 Other; and 2 Not-For-Profit Research Centers.
Most survey respondents had a senior job role or position which was in descending order:
27 research scientists; 11 senior scientists/researchers; 10 professors/assistant professors;
10 section/group leaders; 8 directors; 5 principal investigators; 5 department heads; 4
others; 3 outsourcing managers; 3 vice presidents; and 2 lab managers.
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4. Outsourced Ion Channel Testing Trends 2013
Survey results were expressed as an average of all survey respondents. In addition, where
appropriate the data was reanalyzed after sub-division into the following 5 survey groups:
1) Large Pharma; 2) Other Screening Labs; 3) Academic Research; 4) Europe; and 5) North
America.
Only 25% of respondents have outsourced the primary screening of ion channels to date
and most of this was done at ChanTest. Some feedback on why some respondents have
not yet outsourced ion channel primary screening was documented.
The current (2013) level of interest in outsourcing ion channel primary screening was low
and most of this was small-scale (10-100 compounds screened). The median pricepoint
for accessing this outsourced primary screening was $1-$2 maximum price per data point.
Of those respondents interested/involved in outsourcing primary screening a median of 2
programs per year were outsourced today (2013). The preferred platform accessed was
automated patch-clamp (APC).
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outsourced-ion-channel-testing-trends-2013.html .
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5. Outsourced Ion Channel Testing Trends 2013
A pain-inflammation channel panel was most wanted panel for selectivity profiling.
The preferred platform technology for selectivity profiling to be accessed at a service
provider was APC.
After manual patch clamp the preferred vendor’s platform for patch clamping data was
Sophion QPatch HT.
The median use of outsourced selectivity profiling today (2013) was 100-250 data points
per year.
Only 35% of respondents have outsourced selectivity profiling of ion channels to date and
most of that was done at ChanTest.
Data quality (e.g. GΩ versus MΩ seal data) was rated of greatest influence in selecting an
ion channel selectivity profiling provider.
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