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OpioidAnalgesics2008
1.
Opioid Analgesics Opioid
Analgesics
2.
3.
4.
5.
6.
7.
8.
Structure of Morphine
9.
‘Tinkering’ with the
structure of morphine produced heroin
10.
11.
Heroin is addictive
because it crosses the BBB more quickly than morphine.
12.
13.
14.
15.
16.
17.
The C3 hydroxyl
group is necessary for activity. (The methyl ether is only 0.1% as active)
18.
19.
‘Tinkering’ with the
morphine structure can produce useful painkillers
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