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International Journal of Trend in Scientific Research and Development (IJTSRD)
Volume 4 Issue 4, June 2020 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470
@ IJTSRD | Unique Paper ID – IJTSRD31007 | Volume – 4 | Issue – 4 | May-June 2020 Page 665
Understanding the Need of Data Integration in E- Healthcare
Mrs. Shashi Rekha. H.1, Dr. Chethana Prakash. M2, Dr. K. Thippeswamy3
1,3Visvesvaraya Technological University, Mysuru, Karnataka, India
2B.I.E.T, Davangere, Karnataka, India
ABSTRACT
This paper discusses the current scenario of e- healthcare and different
dimensions of Big data in healthcare and the importance of data integrationin
e- health care and the challenges associated with data integration and
associated uses of data integration with respect to different use cases which
might be helpful to physician’s decision making because the data driven
decision making involves combination of heterogeneous data which includes
Electronic Health Record containing different types of data and connected
healthcare organization in order to provide value based connectedhealthcare
which would be useful to primary healthcare center located at different
location because patients suddenly expect their healthcare experiences to be
as exceptional and as transparent as those of retail orbanking,andphysician’s
have to scramble to adjust to these new expectations due to lack of data
integrity.
KEYWORDS: E- Healthcare, Big Data, Heterogeneous data, Data Driven Decision
Making, Connected Health Care Organization
How to cite this paper: Mrs. Shashi
Rekha. H. | Dr. Chethana Prakash. M | Dr.
K. Thippeswamy "Understanding the
Need of Data Integration inE- Healthcare"
Published in
International Journal
of Trend in Scientific
Research and
Development
(ijtsrd), ISSN: 2456-
6470, Volume-4 |
Issue-4, June 2020,
pp.665-667, URL:
www.ijtsrd.com/papers/ijtsrd31007.pdf
Copyright © 2020 by author(s) and
International Journal ofTrendinScientific
Research and Development Journal. This
is an Open Access article distributed
under the terms of
the Creative
Commons Attribution
License (CC BY 4.0)
(http://creativecommons.org/licenses/by
/4.0)
1. INTRODUCTION
Currently, computers dominate the world, and thereforethe
different data types are stored in computer warehouses.The
biggest challenge in the big data era lies in collecting and
storing data, the real challenge is the integration of all kinds
of data sources to find successful big data value creation.
This occurs, because many of these data sources have to be
integrated with other data sources, becausethedata sources
integrated or not often contain data variables thathaveto be
further processed to create useful information. Data sources
vary in terms of content, sources, and have to be present
within the commercial data environment. There is a strong
belief that instead of focusing on the “V” i.e volume of big
data, the real challenge lies in addressing the “V” i.e variety
of data sources, especially because every source adds a
specific dimension to thehealthcaredata environment.Right
now ,there is an existence of large number of autonomous
and heterogeneous datastoragerepositories availableonthe
worldwide information storage structure makes it
impossible for users to be aware of the locations,
structure/organization, and languages used in queries and
semantics of the data stored in various repositories in
different formats. So, there is a critical need to enhance
current browsing, navigation and information retrieval
techniques which focuses on information content sharing
and semantics. In any strategy,which focusesoninformation
content, the most difficult problem is usage of different
vocabularies used to describe similar information across
different domains. Big data dominates in various disciplines
of real time applications such as E- governance, Smart Tran
sportation, E- healthcare where the concept of data
integration plays an importantrole becausethedata consists
of heterogeneous data formats and online sharing of this
data plays an important role in rapid decision making
process [1]
2. E- healthcare:
In coming years, the healthcare field generates large
amounts of data in different data formats. The value based
treatment in hospitals and connected organization and
digitization of data prefers to have the computerized view of
data rather than hard copy format. The health care data
includes Electronic Medical Record (EMR) of patient’s data,
clinical reports, doctor’s prescription, diagnostic reports,
medical images,pharmacyinformation,and healthinsurance
related data. [2]. All these information collectively forms Big
Data in Health care. By employing the analytics of big data in
healthcare would produce the predicted results by
understanding the data given to improve thehealthcareand
life time expectancy, proper treatment at early stages at low
cost to the unreachable people in the mean time. The
healthcare data is rich in informationbutpoorinknowledge.
There is a lot of data available within the healthcare systems
which are rich in knowledge. But, there is a shortage of
effective analysis tools to discover hidden relationships
among associated types of data. An effective analysis tool
helps to discover hidden relationships amongdifferenttypes
of data which are heterogeneous data. [3]. Healthcare
analytics is the systematic usage of healthcare data and
IJTSRD31007
International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD31007 | Volume – 4 | Issue – 4 | May-June 2020 Page 666
analysis tools to get associated and related insights by
applying analytical methods ,e.g. such as mathematical
statistical, contextual, quantitative,predictive,cognitive, and
other techniques, to drive data driven fact -based decision
making for Predicting ,Diagnosing ,Planning & Managing ,
and Learning in healthcare[4]. E-Health clouds are
increasing popularly by facilitating the storage and sharing
of big data in healthcare. But, adoption of such systems also
brings about a series of challenges, especially related to the
security and privacy of highly sensitive health data
associated with the complete information of patient related
data andintegration of heterogeneous data, data
visualization and interpretation etc [5]. As per Dr. Martin
Makary, professor of surgery and health policy at Johns
Hopkins School of Medicine “People don'tjust diefromheart
attacks and cancer, they die from system wide failings and
poorly coordinated care.[6]
3. Data Integration:
It combines the data obtained from many sources and
sensors into a coherent data store, as in data warehousing.
These sources may include multiple database, data cubes or
flat files etc., store under a unified schema and that usually
reside at a single site. Data integration is the problem of
combining data residing at different sources in different
formats and for providing the user with a unified view of
these data [8, 9, 10]. The problem of designing data
integration systems is important in current real time E-
healthcare applications in rural healthcare system and is
characterized by a numberof issues thatareinteresting from
a theoretical point of view. At higherlevel,data integrationis
defined as the combination of technical and business
processes used to combine data from disparate sources into
meaningful and valuable information. However, data
integration can mean a lot of differentthingsacross different
contexts [11]. Data integration involves gathering of data in
different formats from different source repositories which
can be on cloud or on-premises or both and putting it in
unified form to be used in reporting and analysis. In short,
data integration process centralizes data and makes it large
which looks difficult to analyze if not integrated properly as
shown below in the fig 1.
Figure 1: Healthcare Information Aggregation
4. Challenges of Data Integration:
Clinical data integration, however, has many challenges.
Following is a discussion of the top existing challenges:
4.1. Clinical data rarely adheres to a schema, data
dictionary, or data definition.
Discrete clinical data can beingestedandstoredindatabases
by a wide range of electronic medical record(EMR)stored in
hospitals .These hospitals store clinical data in proprietary
schema structures, and the schema structures ofa particular
hospital may not be interoperable with those of other
hospital .This creates a challenge, since understanding the
data in its elemental form takes a lot of time and effort.
4.2. Standard formats like HL7 v2 and HL7 v3 (CCD,
CCDA, etc.) exist, but vendors are not consistentin
their implementation.
Most EMR systems rely on HL7 v2 for messaging, which is a
very loose standard with a lot of variability in
implementation. To ensure interoperability between
different EMR systems, HL7 v3 was proposed as a semantic
data representation, messaging, and document standard for
patient medical information. However, apart from the
document standard (CDA, CCDA), HL7 v3 has not had the
adoption that was initially expected. Furthermore, even
when EMR systems use HL7 v3, like for the CCDA document
standard, loopholes can be exploited by vendors to produce
CCDA-compliant documents that are still extremely
inoperable between systems. These issues have rendered
interoperability between EMR systems extremely
challenging.
4.3. A huge amount of valuable clinical data exists as
unstructured free text.
Most of the data recorded by physicians and providers is
unstructured in nature, as physicians may not have the time
or inclination to record data in structured formats. On the
other hand, most health informationtechnologysystems use
structured data to manage a wide range of healthcare
processes that include care management, measuring
performances such as clinical quality, cost re-imbursement,
and reporting. If patient data elements for procedures,
diagnosis, and medications are not recorded in a structured
format, these healthcareprocesses fora patientareimpacted
since they cannot be tracked and measured properly.
A typical example is a patient’s foot exam, for which the
physician writes documentation, recording “pedal calluses”
in an unstructured note. Even though the patient underwent
a foot exam and was diagnosed with “pedal calluses,” the
quality measure does not record the fact that a foot examfor
this patient was completed. Furthermore, since health
information technology systems do not use unstructured
data widely, the required interventions for managing “pedal
calluses” are not triggered.
4.4. Reconciliation of clinical data with claims data is
onerous.
As described earlier, claims and clinical data are meant for
different purposes. Claims data is structured and is meantto
provide a record of all the medical services that incur cost.
Clinical data is often unstructured, and it records
information about the medical care provided to the patient.
Furthermore, clinical and claims data use different codesets
to record diagnosis, procedure, and medicationcodes.These
International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD31007 | Volume – 4 | Issue – 4 | May-June 2020 Page 667
differences between claims and clinical data make a
straightforward reconciliation of information from the
claims and clinical records laborious and time-consuming.
Healthcare data is quite complex and any text analytics/NLP
solution needs to offer the following capabilities:
A. Recognizing synonyms of medical terms,andpresenting
the results accordingly. For example, “Hand pain” and
“Finger pain” mean the same thing.
B. Processing large volumes of data in terms of millions of
records.
C. Recognizing the context of healthcare terms, for
example the terms “Family history of myocardial
infarction,” “No MI,” and “MI ruled out” mean different
things, so they must be handled accordingly to predict
the disease. [11]
5. Benefits of Data Integration in E- healthcare:
The significance of data integration increases in hospitals &
connected organizations because they are in use of more
systems and applications. Organizations need the data
stored in different data format in different systems to be
brought together to achieve a comprehensive unified view.
Then, doctors can use this integrated data to enhance up
data driven computational intelligencetoprovideconnected
value based health care located at different locations [13].
The benefit of data integration includes the following:
 A single-view of the data available by keeping data
synchronized across organizations and systems.
 A Comprehensive, informative view of patients EMR.
 Availability of data to doctors and staff across an
organization in Unified view.
 Opportunities for analyzing and predicting data driven
and data-based decision making based on high quality
and complete data of the patient available.
6. Conclusion:
This paper discusses the significanceofdata integrationin E-
healthcare along with big data characteristics in E-
healthcare comprising of heterogeneous dataandchallenges
associated with data integration and the benefits of data
integration when the data is collected from diversified
sources to make data driven decision making in order to
provide value based healthcare useful for the doctors and
nurses while providing online services to E- healthcare
system which would accelerate Universal Health Coverage
and more and more organizations can realize the growing
importance of data mobility which can increase care team
productivity to deliver better patient outcomes located at
different locations. The need of the hour is to provide
Connected Value based healthcaretotheunreachablepeople
located in different places.
References
[1] Mohit Dayal∗ and Nanhay Singh Indian Health Care
Analysis using Big Data Programming Tool,” Twelfth
International Multi-Conference on Information
Processing-2016 (IMCIP-2016 “
[2] Muni kumar N, Manjula R,”Role of Big Data Analyticsin
Rural Health Care – A Step Towards Svasth Bharath”,
International Journal of Computer Science and
Information Technologies, vol 5(6), pp 7172-
7178,2014.
[3] Jyoti Soni Ujma Ansari Dipesh Sharma Predictive Data
Mining for Medical Diagnosis: An Overview of Heart
Disease Prediction, International Journal of Computer
Applications (0975 – 8887) Volume 17– No.8, March
2011
[4] Cortada, J.W., Gordon, D., & Lenihan, B. (2012). The
value of analytics in healthcare: from insights to
outcomes. IBM Global Business Services, Life Sciences
and Healthcare, Executive Report.
[5] A Qi Jiang· Muhammad Khurram Khan· Xiang Lu
Jianfeng Ma· Debiao “Privacy preserving three-factor
authentication protocol for e-Health clouds. J Super-
computing(2016) 72:3826–3849 DOI
10.1007/s11227-015-1610-x
[6] http:// www.EHRintelligence .com
[7] Ragavi, B Srinidhi, V S Anitha Sofia “Data Mining Issues
and Challenges: A Review International Journal of
Advanced Research in Computer and Communication
Engineering Vol. 7, Issue 11, November 2018.
[8] T. Kirk, A. Y. Levy, Y. Sagiv, and D. Srivastava. The
Information Manifold. In Proceedings of the AAAI 1995
Spring Symposium on Information Gathering from
Hetero- generous, Distributed Environments, pages 85–
91, 1995.
[9] R. Hull. Managing semanticheterogeneity indatabases:
A theoretical perspective. In Proc. of the 16th ACM
SIGACT SIGMOD SIGART Symp. onPrinciplesofDatabase
Systems (PODS’97), 1997.
[10] J. D. Ullman. Information integration using logical
views. In Proc. of the 6th Int. Conf. on Database Theory
(ICDT’97), volume 1186 of Lecture Notes in Computer
Science, pages 19–40. Springer, 1997.
[11] http://dynamic.globalscape.com/files/whitepaper_5Ri
ngsDataIntegrationHell.pdf
[12] Clinical Data Integration for Health Plans: Top 5
Challenges and Solutions”ZEOMEGAPopulationHealth
Management Solution [White Paper].
[13] http://dynamic.globalscape.com/files/whitepaper_Wh
at is Data Integration.pdf.

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Understanding the Need of Data Integration in E Healthcare

  • 1. International Journal of Trend in Scientific Research and Development (IJTSRD) Volume 4 Issue 4, June 2020 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470 @ IJTSRD | Unique Paper ID – IJTSRD31007 | Volume – 4 | Issue – 4 | May-June 2020 Page 665 Understanding the Need of Data Integration in E- Healthcare Mrs. Shashi Rekha. H.1, Dr. Chethana Prakash. M2, Dr. K. Thippeswamy3 1,3Visvesvaraya Technological University, Mysuru, Karnataka, India 2B.I.E.T, Davangere, Karnataka, India ABSTRACT This paper discusses the current scenario of e- healthcare and different dimensions of Big data in healthcare and the importance of data integrationin e- health care and the challenges associated with data integration and associated uses of data integration with respect to different use cases which might be helpful to physician’s decision making because the data driven decision making involves combination of heterogeneous data which includes Electronic Health Record containing different types of data and connected healthcare organization in order to provide value based connectedhealthcare which would be useful to primary healthcare center located at different location because patients suddenly expect their healthcare experiences to be as exceptional and as transparent as those of retail orbanking,andphysician’s have to scramble to adjust to these new expectations due to lack of data integrity. KEYWORDS: E- Healthcare, Big Data, Heterogeneous data, Data Driven Decision Making, Connected Health Care Organization How to cite this paper: Mrs. Shashi Rekha. H. | Dr. Chethana Prakash. M | Dr. K. Thippeswamy "Understanding the Need of Data Integration inE- Healthcare" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456- 6470, Volume-4 | Issue-4, June 2020, pp.665-667, URL: www.ijtsrd.com/papers/ijtsrd31007.pdf Copyright © 2020 by author(s) and International Journal ofTrendinScientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by /4.0) 1. INTRODUCTION Currently, computers dominate the world, and thereforethe different data types are stored in computer warehouses.The biggest challenge in the big data era lies in collecting and storing data, the real challenge is the integration of all kinds of data sources to find successful big data value creation. This occurs, because many of these data sources have to be integrated with other data sources, becausethedata sources integrated or not often contain data variables thathaveto be further processed to create useful information. Data sources vary in terms of content, sources, and have to be present within the commercial data environment. There is a strong belief that instead of focusing on the “V” i.e volume of big data, the real challenge lies in addressing the “V” i.e variety of data sources, especially because every source adds a specific dimension to thehealthcaredata environment.Right now ,there is an existence of large number of autonomous and heterogeneous datastoragerepositories availableonthe worldwide information storage structure makes it impossible for users to be aware of the locations, structure/organization, and languages used in queries and semantics of the data stored in various repositories in different formats. So, there is a critical need to enhance current browsing, navigation and information retrieval techniques which focuses on information content sharing and semantics. In any strategy,which focusesoninformation content, the most difficult problem is usage of different vocabularies used to describe similar information across different domains. Big data dominates in various disciplines of real time applications such as E- governance, Smart Tran sportation, E- healthcare where the concept of data integration plays an importantrole becausethedata consists of heterogeneous data formats and online sharing of this data plays an important role in rapid decision making process [1] 2. E- healthcare: In coming years, the healthcare field generates large amounts of data in different data formats. The value based treatment in hospitals and connected organization and digitization of data prefers to have the computerized view of data rather than hard copy format. The health care data includes Electronic Medical Record (EMR) of patient’s data, clinical reports, doctor’s prescription, diagnostic reports, medical images,pharmacyinformation,and healthinsurance related data. [2]. All these information collectively forms Big Data in Health care. By employing the analytics of big data in healthcare would produce the predicted results by understanding the data given to improve thehealthcareand life time expectancy, proper treatment at early stages at low cost to the unreachable people in the mean time. The healthcare data is rich in informationbutpoorinknowledge. There is a lot of data available within the healthcare systems which are rich in knowledge. But, there is a shortage of effective analysis tools to discover hidden relationships among associated types of data. An effective analysis tool helps to discover hidden relationships amongdifferenttypes of data which are heterogeneous data. [3]. Healthcare analytics is the systematic usage of healthcare data and IJTSRD31007
  • 2. International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD31007 | Volume – 4 | Issue – 4 | May-June 2020 Page 666 analysis tools to get associated and related insights by applying analytical methods ,e.g. such as mathematical statistical, contextual, quantitative,predictive,cognitive, and other techniques, to drive data driven fact -based decision making for Predicting ,Diagnosing ,Planning & Managing , and Learning in healthcare[4]. E-Health clouds are increasing popularly by facilitating the storage and sharing of big data in healthcare. But, adoption of such systems also brings about a series of challenges, especially related to the security and privacy of highly sensitive health data associated with the complete information of patient related data andintegration of heterogeneous data, data visualization and interpretation etc [5]. As per Dr. Martin Makary, professor of surgery and health policy at Johns Hopkins School of Medicine “People don'tjust diefromheart attacks and cancer, they die from system wide failings and poorly coordinated care.[6] 3. Data Integration: It combines the data obtained from many sources and sensors into a coherent data store, as in data warehousing. These sources may include multiple database, data cubes or flat files etc., store under a unified schema and that usually reside at a single site. Data integration is the problem of combining data residing at different sources in different formats and for providing the user with a unified view of these data [8, 9, 10]. The problem of designing data integration systems is important in current real time E- healthcare applications in rural healthcare system and is characterized by a numberof issues thatareinteresting from a theoretical point of view. At higherlevel,data integrationis defined as the combination of technical and business processes used to combine data from disparate sources into meaningful and valuable information. However, data integration can mean a lot of differentthingsacross different contexts [11]. Data integration involves gathering of data in different formats from different source repositories which can be on cloud or on-premises or both and putting it in unified form to be used in reporting and analysis. In short, data integration process centralizes data and makes it large which looks difficult to analyze if not integrated properly as shown below in the fig 1. Figure 1: Healthcare Information Aggregation 4. Challenges of Data Integration: Clinical data integration, however, has many challenges. Following is a discussion of the top existing challenges: 4.1. Clinical data rarely adheres to a schema, data dictionary, or data definition. Discrete clinical data can beingestedandstoredindatabases by a wide range of electronic medical record(EMR)stored in hospitals .These hospitals store clinical data in proprietary schema structures, and the schema structures ofa particular hospital may not be interoperable with those of other hospital .This creates a challenge, since understanding the data in its elemental form takes a lot of time and effort. 4.2. Standard formats like HL7 v2 and HL7 v3 (CCD, CCDA, etc.) exist, but vendors are not consistentin their implementation. Most EMR systems rely on HL7 v2 for messaging, which is a very loose standard with a lot of variability in implementation. To ensure interoperability between different EMR systems, HL7 v3 was proposed as a semantic data representation, messaging, and document standard for patient medical information. However, apart from the document standard (CDA, CCDA), HL7 v3 has not had the adoption that was initially expected. Furthermore, even when EMR systems use HL7 v3, like for the CCDA document standard, loopholes can be exploited by vendors to produce CCDA-compliant documents that are still extremely inoperable between systems. These issues have rendered interoperability between EMR systems extremely challenging. 4.3. A huge amount of valuable clinical data exists as unstructured free text. Most of the data recorded by physicians and providers is unstructured in nature, as physicians may not have the time or inclination to record data in structured formats. On the other hand, most health informationtechnologysystems use structured data to manage a wide range of healthcare processes that include care management, measuring performances such as clinical quality, cost re-imbursement, and reporting. If patient data elements for procedures, diagnosis, and medications are not recorded in a structured format, these healthcareprocesses fora patientareimpacted since they cannot be tracked and measured properly. A typical example is a patient’s foot exam, for which the physician writes documentation, recording “pedal calluses” in an unstructured note. Even though the patient underwent a foot exam and was diagnosed with “pedal calluses,” the quality measure does not record the fact that a foot examfor this patient was completed. Furthermore, since health information technology systems do not use unstructured data widely, the required interventions for managing “pedal calluses” are not triggered. 4.4. Reconciliation of clinical data with claims data is onerous. As described earlier, claims and clinical data are meant for different purposes. Claims data is structured and is meantto provide a record of all the medical services that incur cost. Clinical data is often unstructured, and it records information about the medical care provided to the patient. Furthermore, clinical and claims data use different codesets to record diagnosis, procedure, and medicationcodes.These
  • 3. International Journal of Trend in Scientific Research and Development (IJTSRD) @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD31007 | Volume – 4 | Issue – 4 | May-June 2020 Page 667 differences between claims and clinical data make a straightforward reconciliation of information from the claims and clinical records laborious and time-consuming. Healthcare data is quite complex and any text analytics/NLP solution needs to offer the following capabilities: A. Recognizing synonyms of medical terms,andpresenting the results accordingly. For example, “Hand pain” and “Finger pain” mean the same thing. B. Processing large volumes of data in terms of millions of records. C. Recognizing the context of healthcare terms, for example the terms “Family history of myocardial infarction,” “No MI,” and “MI ruled out” mean different things, so they must be handled accordingly to predict the disease. [11] 5. Benefits of Data Integration in E- healthcare: The significance of data integration increases in hospitals & connected organizations because they are in use of more systems and applications. Organizations need the data stored in different data format in different systems to be brought together to achieve a comprehensive unified view. Then, doctors can use this integrated data to enhance up data driven computational intelligencetoprovideconnected value based health care located at different locations [13]. The benefit of data integration includes the following:  A single-view of the data available by keeping data synchronized across organizations and systems.  A Comprehensive, informative view of patients EMR.  Availability of data to doctors and staff across an organization in Unified view.  Opportunities for analyzing and predicting data driven and data-based decision making based on high quality and complete data of the patient available. 6. Conclusion: This paper discusses the significanceofdata integrationin E- healthcare along with big data characteristics in E- healthcare comprising of heterogeneous dataandchallenges associated with data integration and the benefits of data integration when the data is collected from diversified sources to make data driven decision making in order to provide value based healthcare useful for the doctors and nurses while providing online services to E- healthcare system which would accelerate Universal Health Coverage and more and more organizations can realize the growing importance of data mobility which can increase care team productivity to deliver better patient outcomes located at different locations. The need of the hour is to provide Connected Value based healthcaretotheunreachablepeople located in different places. References [1] Mohit Dayal∗ and Nanhay Singh Indian Health Care Analysis using Big Data Programming Tool,” Twelfth International Multi-Conference on Information Processing-2016 (IMCIP-2016 “ [2] Muni kumar N, Manjula R,”Role of Big Data Analyticsin Rural Health Care – A Step Towards Svasth Bharath”, International Journal of Computer Science and Information Technologies, vol 5(6), pp 7172- 7178,2014. [3] Jyoti Soni Ujma Ansari Dipesh Sharma Predictive Data Mining for Medical Diagnosis: An Overview of Heart Disease Prediction, International Journal of Computer Applications (0975 – 8887) Volume 17– No.8, March 2011 [4] Cortada, J.W., Gordon, D., & Lenihan, B. (2012). The value of analytics in healthcare: from insights to outcomes. IBM Global Business Services, Life Sciences and Healthcare, Executive Report. [5] A Qi Jiang· Muhammad Khurram Khan· Xiang Lu Jianfeng Ma· Debiao “Privacy preserving three-factor authentication protocol for e-Health clouds. J Super- computing(2016) 72:3826–3849 DOI 10.1007/s11227-015-1610-x [6] http:// www.EHRintelligence .com [7] Ragavi, B Srinidhi, V S Anitha Sofia “Data Mining Issues and Challenges: A Review International Journal of Advanced Research in Computer and Communication Engineering Vol. 7, Issue 11, November 2018. [8] T. Kirk, A. Y. Levy, Y. Sagiv, and D. Srivastava. The Information Manifold. In Proceedings of the AAAI 1995 Spring Symposium on Information Gathering from Hetero- generous, Distributed Environments, pages 85– 91, 1995. [9] R. Hull. Managing semanticheterogeneity indatabases: A theoretical perspective. In Proc. of the 16th ACM SIGACT SIGMOD SIGART Symp. onPrinciplesofDatabase Systems (PODS’97), 1997. [10] J. D. Ullman. Information integration using logical views. In Proc. of the 6th Int. Conf. on Database Theory (ICDT’97), volume 1186 of Lecture Notes in Computer Science, pages 19–40. Springer, 1997. [11] http://dynamic.globalscape.com/files/whitepaper_5Ri ngsDataIntegrationHell.pdf [12] Clinical Data Integration for Health Plans: Top 5 Challenges and Solutions”ZEOMEGAPopulationHealth Management Solution [White Paper]. [13] http://dynamic.globalscape.com/files/whitepaper_Wh at is Data Integration.pdf.