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Co-infection of Chronic Lyme Disease Ehrlichiosis May Bring About Cancers
1. Co-infection of Chronic Lyme Disease
Ehrlichiosis May Bring About Cancers
Co-infection of Chronic Lyme Disease
Ehrlichiosis May Bring About Cancers
Patients who actually suffer from chronic Ehrlichiosis are often misdiagnosed as having
autoimmune disorders or other chronic disease with similar symptomologies, as
Ehrlichiosis is generally not tested for. Symptoms typically associated with this infection
are a high fever, headache, chills, as well as muscular aches and pains. These closely
mimic those often linked to other tick-borne diseases.
Ehrlichiosis Essentials
Ehrlichiosis comes in two specific forms including Human Monocytic Ehrlichiosis (HME)
and Human Granulocytic Ehrlichiosis (HGE) and commonly originate from the bite of
different ticks. The Lone Star tick (Amblyomma Americanum) bite is a likely carrier of
HME, while HGE has been linked to the bites of both the Deer tick (Ixodes Scapularis)
and the Western blacklegged tick (Ixodes Pacificus.) The dog tick (Dermacentor
Variabilis) is known to transmit both HME and HGE.
Ticks that carry Ehrlichiosis are also known to carry and transmit Lyme disease as well.
For this reason, patients with Ehrlichiosis should also be tested for Lyme as well.
Can Ehrlichiosis be Passed in Blood Transfusion? Yes!
2. With the unending demand for blood in the medical community, it is not surprising that
the time to test donations/ supplies for Ehrlichiosis or other tick borne infections is
passed over. Rather the supplies are tested for hepatitis and HIV but beyond that, no
much else. In parts of the Northeast, it is suspected that Lyme and many of its co-
infections are found in great numbers in blood donors and as a result, transfusion
supplies.
Ehrlichiosis – The Central Nervous System Invader
In routine central nervous system (CNS) radiological studies, analyses of cerebrospinal
fluid (CSF) samples are seldom pursued. Typically, such tests are prompted only when
primary care physicians detect specific symptoms or signs that tip the need for more
information. In such circumstance when CSF samples were examined (in 15 of 57
patients,) 8 of the 15 were found abnormal. The most common abnormalities found
among the abnormal 15 percent were lymphocytic pleocytosis and elevated protein
levels.
Ehrlichiosis - undetected Infection with ties to Cancer
There are four bacteria known to survive and propagate within human neutrophils and
their bone marrow origins - Ehrlichiosis is one of them.This tick-transmitted rickettsial
pathogen, anaplasma phagocytophilum, is a causative agent of human granulocytic
anaplasmosis and is found in the direct family line of Ehrlichiosis.
About 70 percent of all white blood cells are neutrophils – cells considered to be
unsuitable hosts by intracellular bacteria as they are short-lived and serve as primary
defense cells, armed with significant antimicrobial apparatus.
A. phagocytophilum infection can alter neutrophil functions and result in clinical disease.
Moreover, this infection can inhibit or retard apoptosis, oxidative burst, and
phagocytosis, while activating degranulation and cytokine/chemokine production – often
leading to cancer. At this time it is impossible to say how many infections are cancer
causatives, but this one certainly seems to have a link suggesting that leukemia and
other lymphatic cancers are catalyzed by epigenetic shifts resultant of Ehrlichiosis.
Choi KS, Grab DJ, Dumler JS (2004) Anaplasma phagocytophilum infection induces protracted neutrophil
degranulation. Infect Immun 72: 3680–3683.
Ehrlichiosis and Immuno-compromised Patients: Recipe
for Disaster
The zoonotic illness Ehrlichiosis is caused by Ehrlichia species - bacteria that are
decidedly pleomorphic, intracellular, rickettsia-like organisms.[2-4] Ehrlichia present a
clinical spectrum, or symptomology that can vary from a mild, influenza-like illness, to a
fulminant sepsis syndrome. Typically, we find that Ehrlichiosis is self-limiting and not
fatal with death rates in large, unselected series ranging from 1 to 8 percent [3,6-8] -