This patient is a 34-year-old Filipino man who presented with dizziness, loss of appetite, vomiting, and generalized weakness. His history and lab results are consistent with a diagnosis of aplastic anemia. Aplastic anemia is a bone marrow failure where the production of red blood cells, white blood cells, and platelets is suppressed, leading to pancytopenia. Treatment options include supportive care like transfusions, immunosuppressive drugs, and bone marrow transplant, with outcomes varying based on a patient's age and availability of a histocompatible donor.

1. CASE MANAGEMENT Group 1

12. Laboratory test

14. Blood chem Result Normal value Urea nitrogen 4.8 mmol/L 2.2-8.2mmol/L Creatinin 1.9 5-17 Phos Alk 32.8 10-35 SGPT 50.9 5-47

16. What are you impression?

17. APLASTIC ANEMIA

19. APLASTIC ANEMIA What happens when the bone marrow shuts down?

20. What is Aplastic Anemia ? - Aplastic Anemia is a bone marrow failure disease .

22. Peripheral blood Smear Peripheral blood Smear

23. HYPOCELLULAR BONE MARROW IN APLASTIC ANEMIA

28. Pathophysiology of aplastic anemia

38. Presentation of Anemia, Neutropenia and Thrombocytopenia Hemorrhagic lesion of the gums in a patient with aplastic anemia caused by infection with Capnocytophaga ochraceus; such lesions are easily confused with those of herpes simplex.

39. 26-year-old woman with acute aplastic anemia and 1 day of facial pain/swelling. Mouth open involuntarily due to perioral edema. Needle aspirate of small purplish area near right alar revealed P. aeruginosa.

40. Aplastic anemia. Oral leukoplakia in dyskeratosis congenita.

41. Treatment Options Bone Marrow Transplant Growth Hormones Immune Suppressive Therapy Supportive Care

49. Thank you ?