This presentation was given as part of a keynote address at the 2019 GlobusWorld Conference in Chicago, IL by Rafael Vescovi, Postdoctoral Scholar at Argonne National Laboratory and Bobby Kasthuri, Neuroscience Researcher, Argonne National Laboratory, Assistant Professor in Neurobiology, University of Chicago.

1. May 1st, 2019
GlobusWorld
RAFAEL VESCOVI, PHD
BRAINS AND GLOBUS
Past, Present and Future..

2. 3 YEARS AGO
A student came from Brazil to do tomography…
• 1-5 minutes acquisition
• 10-20 minutes of computation
• 10 minutes for analysis
• 10gb of raw+final data

3. XRAY RECONSTRUCTION OF THALAMO-
CORTICAL SAMPLE
3

4. XRAY RECONSTRUCTION OF CORTEX SAMPLE

5. SEGMENTATION OF CORTEX SAMPLE

6. THE NECESSITY
▪Multiple samples
▪Multiple users
▪Multiple experiments
– X-ray Tomography
– Electron Microscopy
– MRI
▪Different User levels
– Beamline physicists
– Biologists
– HPC power users
▪Distribution of large amounts of data
▪Managing all of the above

7. THE SOLUTION
• Each user/group has
its own folder and
group.
• Permissions are given
by the user itself
• No need for power
users

8. Storage
Visualizing!!
THE BASIC PIPELINE
Camera PC1 PC2
Processing!!
Decision
The average time
per sample was
around 1 hour.

9. GLOBUS AUTOMATE

10. THE BASIC PIPELINE
Camera PC1 PC2
Storage
HPC
Visualization
Decision
Without having to transfer,
process and decide. The
time per sample is only
limited by the time it takes to
acquire the data!!

11. GLOBUS DATA PORTAL

12. FUTURE IMPLEMENTATIONS
▪Real time data processing
–1Pb/month
–Minimal user interaction
–Integration of web apps for
visualization and tracing
▪Portal for different types of data
–With trigger capabilities

13. FUTURE EM PIPELINE
13

14. AUTOMATIC VESSEL SEGMENTATION
Demovessels.kasthurilab.com

15. AUTOMATIC CELL SEGMENTATION
Democells.kasthurilab.com

16. ELECTRON MICROSCOPE SEGMENTATION
16

17. WHOLE MOUSE BRAIN X-RAY
Wholebrain.kasthurilab.com
17

18. WHOLE MOUSE BRAIN X-RAY
Cells and dentrites
18

19. www.anl.gov
THANK YOU ALL!