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Quarantine and the elderly
1. The Elderly in Quarantine
Marc Evans M. Abat, MD, FPCP, FPCGM
Internal Medicine-Geriatric Medicine
Head, Center for Health Aging, and Section of Geriatrics, The Medical City
Clinical Associate Professor, Division of Adult Medicine, Department of Medicine, PGH
2. Outline
Aging and Frailty
Some Realities of the Filipino Elderly
COVID-19 and the Elderly
Physical Effects of Quarantine
Mental Effects of Quarantine
Management Approach
4. âŚ. accumulation of changes responsible for the
sequential alterations that accompany advancing age
and the associated progressive increases in the chance
of disease and death. Harman D, Proc National Academy of Science USA, 1991
AgingâŚ
8. High Vulnerability
Low Vulnerability Less Noxious Insult
Very Noxious Insult
Predisposing Factors
or Vulnerabilities
Precipitating Factors
or Insults
9. Frailty
Refers to a loss of physiologic reserve that makes a
person susceptible to disability from minor
stresses.
An inherent vulnerability to challenge from the
environment.
12. older individuals comprise 7.5% of the total
population equivalent to 7.5 million
individuals
only 30% receive social pension of P500
monthly (USD$10) and 40% receive no
pension at all
Difficulties in healthcare access, rural higher
than in urban setting
Int Psychogeriatr. 2020 Apr 30 : 1â5.
13. Majority of older Filipinos are deeply
religious and have strong views of Godâs
role in health and well-being
Going to church regularly and attending
church activities and gatherings are part of
everyday life for older Filipinos
Concept of multigenerational households
Int Psychogeriatr. 2020 Apr 30 : 1â5.
16. High risk for hospitalization and DEATH
⢠Due to more severe COVID-19 illness
⢠Due to worsening of co-morbidities
⢠Due to possible frailty
https://www.cdc.gov/coronavirus/2019-ncov/covid-
data/investigations-discovery/hospitalization-death-by-age.html
As of June 24, 2021
20. Consequences of unguided exercises at home
Older people expressed the need to perform physical
activity at home
increase the risk of injury due to a lack of adapted
equipment or poor knowledge of the physical exercises
to perform
JMIR Aging. 2020 Jan-Jun; 3(1): e19007
21. Non-communicable diseases (NCDs)
increased morbidity from chronic disease
and with higher all-cause mortality
â˘Detrimental health behaviours, such as smoking
and reduced physical activity may mediate over
30% of this effect
https://blogs.bmj.com/bmj/2020/04/09/the-effects-of-
isolation-on-the-physical-and-mental-health-of-older-adults/
22. Increased NCD progression
â˘Reduced OPD access
â˘Problems with medication supply access
â˘Fears about going to a healthcare facility
â˘Shifted focus of healthcare resources to COVID-19
care
Aging Clin Exp Res. 2020; 32(7): 1189â1194.
https://unsdg.un.org/sites/default/files/2020-05/Policy-Brief-The-Impact-of-
COVID-19-on-Older-Persons.pdf
23. Quarantine and nutrition
Change in
nutritional habit
⢠Reduced
availability
⢠Limited access
⢠Unhealthy
food
⢠Psychological
factors
Weight gain and
nutrition loss
⢠Oxidative
stress
⢠Inflammation
Increased NCD
burden
⢠Cardiovascular
risk
European Journal of Clinical
Nutrition volume 74, pages852â855(2020)
28. Stress in the old vs. the young
older show less emotional distress than younger participants
⢠elderly had a greater resilience than the younger participants
without gender differences
economic losses and the increase in the use of anxiolytics are
related to distress
Am J Geriatr Psychiatry 28:10, October 2020
29. Loneliness and dementia
1,905 nondemented participants at baseline, drawn from the longitudinal
Betula study in Sweden, with a follow-up time of up to 20 years (mean 11.1
years)
âDo you often feel lonely?â
increased risk of all-cause dementia ( HR 1.46, 95% CI 1.14â1.89), and
Alzheimerâs disease (HR = 1.69, 95% CI 1.20â2.37)
The Journals of Gerontology: Series B, Volume 75, Issue 5, June
2020, Pages 919â926
31. Mental health and physical activity
1,046 older adults over the age of 50 in North America
97% adhered to social distancing guidelines
Participants who performed greater levels of physical activity experienced lower
levels of depression-like symptoms when age, sex, and education were accounted for
Greater light and strenuous activity predicted lower depression-like symptoms.
Am J Geriatr Psychiatry 28:10, October 2020
32. need to help older adults integrate simple,
safe ways to stay physically active in a
limited space
â˘Booklets
â˘Online videos and resources
â˘Volunteer groups
JMIR Aging. 2020 Jan-Jun; 3(1): e19007.
33. Start low, go slow but keep
on going (symptom-limited)
Safe equipment (even if
improvised)
Involved the family and
friends (even via
teleconferencing)
36. Medical concerns
Regular monitoring
Ensure medication adherence and reconciliation
Watch out for signs of deterioration
Eliminate/reduce noxious habits e.g. cigarettes or alcohol
37. Nutritional support
Availability of nutritious food
Education on appropriate portions
Financial support for procurement
Logistic support for preparation
40. Not just how, but how well to communicate
During phone
call
⢠Watch the
same show
together
⢠Have grandkids
tell stories or
vice versa
Using technology
⢠Share pictures
and videos
Be specific
⢠What are you
eating for
lunch?
⢠What are you
doing now?
http://ocm.auburn.edu/experts/2020/03/261525-covid19-elderly-
population.php
Aging is what happens when accumulation of changes (which can happen on multiple levels of complexity ď from the genome, epigenetic levels, biochemical processes, macromolecules and tissues, organ systems) responsible for sequential alterations with advancing age
Associated with increased chance of disease and death
Changes start at genomic and molecular levels. These eventually lead to decreases in physiologic capacity. This explains why as some people age, they start complaining of not being able to do the things they usually do despite being generally well.
A decline in homeostasis happens. We will discuss this further in the next slide. This leads to an increased susceptibility to disease (even with minor insults for some persons).
All of this eventually lead to increased mortality as one ages.
Now we obviously see that not all older people are the same.
We know of people in their 70s or 80s who are still very active and functional for their age. There are stories of what we call SUPER SENIORS who are master athletes in their respective fields (the Indian marathoner, bodybuilders like Schwarzenegger, etc.)
On the other hand there are other persons who are in their 50s or 60s yet are already functionally limited, or even disabled due to the accumulated effects and complications of diseases
This is the concept of chronological age vs biological age. The former is the numerical count of time of a personâs existence. The other is the actual manifestations of changes in the function of the entire body that may be phenotypically discordant with time
As one ages, and due to numerous factors like baseline health, presence of vices, or disease, the amount of physiologic reserve (the amount of bodily resources that are used to overcome stress) decreases. This is because the body starts to use more of these resources to maintain equilibrium. This is the concept of homeostenosis-the ability to maintain equilibrium becomes narrower.
At some point, if the physiologic reserve remaining is overcome, adverse outcomes happen like what we call geriatric syndromes, hospitalization and death
As was discussed earlier on biological age, the physiologic reserve may vary from person to person depending on inherent and modifiable factors like genetics, lifestyle, presence of comorbidities, vices, environment, education, etc.
Those who are vulnerable due to the multiplicity of their risk factors only needs a minor insult to manifest with problems.
On the other hand, those with minimal risk factors or with minimal vulnerability would take either one big insult or successive moderate insults to manifest with problems
In older patients, the slopes and baselines are variable, and may be challenging to document or measure. In real life, this can be estimated by a number of maneuvers.