Positron Emission Tomography In Oncology

POSITRON EMISSION TOMOGRAPHY IN ONCOLOGY F De Winter, C Van de Wiele, RA Dierckx Ghent University and University Hospital, Belgium

POSITRON EMISSION TOMOGRAHY ,[object Object],[object Object],[object Object]

NUCLEAR MEDICINE : DIAGNOSIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Radiopharmaceutical (eg FDG) electron 511 keV gamma ray 511 keV gamma ray positron positron + electron = 2 * 511 Kev (180°)

POSITRON EMISSION TOMOGRAHY SYSTEM

REIMBURSEMENT FOR FDG PET IN BELGIUM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

REIMBURSEMENT FOR FDG PET ,[object Object],[object Object],[object Object],When other imaging modalities are not conclusive...

REIMBURSEMENT FOR FDG PET ,[object Object],[object Object],[object Object],[object Object],When other imaging modalities are not conclusive...

REIMBURSEMENT FOR FDG PET ,[object Object],[object Object],[object Object],[object Object]

LOCOREGIONAL RESTAGING : BRAIN TUMOR RECURRENCE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

LOCOREGIONAL RESTAGING : HEAD AND NECK CANCER

POSSIBLE PET INDICATIONS FOR HEAD AND NECK CANCER ,[object Object],[object Object],[object Object],[object Object]

HEAD AND NECK CANCER ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HEAD AND NECK CANCER : II LOCAL RECURRENCE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HEAD AND NECK CANCER : LOCAL RECURRENCE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HEAD AND NECK CANCER CLINICAL STUDY ,[object Object],[object Object]

HEAD AND NECK CANCER CLINICAL STUDY ,[object Object],[object Object],[object Object],[object Object]

RESTAGING OF LYMPHOMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

RESTAGING OF LYMPHOMA ,[object Object],[object Object],[object Object],[object Object]

LYMPHOMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

RESTAGING OF OVARIUM CARCINOMA ,[object Object],[object Object],[object Object],[object Object],[object Object]

COLORECTAL CARCINOMA : RESTAGING ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

COLORECTAL CARCINOMA : RESTAGING ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

COLORECTAL CARCINOMA : RESTAGING ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

STAGING OF LUNG CARCINOMA ,[object Object],[object Object],[object Object]

LUNG CARCINOMA : I SOLITARY PULMONARY NODULE DIFFERENTIAL DIAGNOSIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

SOLITARY PULMONARY NODULE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

SOLITARY PULMONARY NODULE gold standard histology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

DIFFERENTIAL DIAGNOSIS OF SOLITARY PULMONARY NODULES

SOLITARY PULMONARY NODULES: CONCLUSIONS (Rigo et al) ,[object Object],[object Object],[object Object],[object Object],[object Object]

LUNG CANCER ,[object Object],[object Object],[object Object],[object Object],[object Object],Therapy/prognosis depends on TNM stage

LUNG CANCER : II&III STAGING OF NSCLC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

STAGING OF NSCLC ,[object Object],[object Object],[object Object],[object Object]

NSCLC MEDIASTINAL STAGING ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

STAGING OF NSCLC : N STAGING Van Steenkiste et al, Chest, 1997

STAGING OF NSCLC : N STAGING ,[object Object],[object Object],FDG-PET : high uptake in primary tumour but no focal abnormality in the mediastinum

STAGING OF NSCLC : M STAGING ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

STAGING OF NSCLC : CONCLUSIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

STAGING MALIGNANT MELANOMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

STAGING PANCREAS TUMOR ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

FDG PET: PRACTICALITIES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

FDG PET: PRACTICALITIES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

TOWARDS … ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

BREAST CARCINOMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

BREAST CARCINOMA, T ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

BREAST CARCINOMA ,[object Object],[object Object],[object Object],[object Object],[object Object]

BREAST CARCINOMA, N axillary ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

BREAST CARCINOMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

BREAST CARCINOMA : NODAL STAGING

BREAST CARCINOMA : METASTASIS ? Bone scan suspicious; MRI doubtful; PET neg (TN)

HEAD AND NECK CANCER : I STAGING ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

N STAGING: COMPARISON OF FDG PET WITH CONVENTIONAL STAGING ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HEAD AND NECK CANCER ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

HEAD AND NECK CANCER CLINICAL STUDY ,[object Object],[object Object],[object Object]

IMPORTANCE OF METABOLIC PREPARATION

Positron Emission Tomography In Oncology

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