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McKinsey Greater China Healthcare


China’s Healthcare Reform:
Moving beyond
reading of the tea leaves
McKinsey Greater China Healthcare




July 2009




China’s Healthcare
Reform: Moving beyond
reading of the tea leaves

Ari Silverman
Amie Chu
Yehong Zhang
Franck Le Deu
Yinuo Li
Rajesh Parekh
4




    Introduction
McKinsey Healthcare
China’s Healthcare Reform: Moving beyond reading of the tea leaves                                                    5




               China’s eagerly anticipated healthcare reform has finally been
               introduced, and it comes with the promise of a hefty investment
               into the healthcare system. As the reform implementation gets
               underway, executives at pharmaceutical companies (pharmacos)
               are trying to understand the specific implications for their own
               business and how they should think about changing their strategy/
               plans for China. While there are open questions about the reform
               implementation at the local level, we believe the direction is now
               relatively clear, and pharmacos should move beyond the ‘reading of
               the tea leaves’ that has occupied China healthcare observers for the
               past few years.

               The reform points to some interesting new opportunities for
               pharmacos, as well as some real challenges to their core business.
               At the same time, reform will not change many of the fundamental
               drivers of the Chinese pharmaceutical market — and as such, it is
               important that executives at pharmacos do not get ‘distracted’ by the
               reform. As executives position their companies to succeed in the
               changing environment, they need to ensure that their organization
               stays focused on day-to-day execution and continue to build the core
               capabilities required for a winning pharma business in China1.

               In this paper, we lay out the key elements of the Chinese healthcare
               reform, identify four areas of opportunities and related threats for
               pharmacos, and outline how pharmacos can best plan to win in the
               new environment.




               1   For more details please refer to the earlier publication from McKinsey & Company titled “Driving
                   Growth in Turbulent Chinese Pharmaceutical Market – Part 2”.
6




    Key elements
    of the reform
McKinsey Healthcare
China’s Healthcare Reform: Moving beyond reading of the tea leaves                                                                                                   7




               In early 2009, China’s State Council announced the long-awaited and much-
               debated healthcare reform. The initial announcements have been followed by
               a serious of policy documents that describe in greater detail how the various
               agencies plan to carry out the implementation. Most recently in late July, the
               General Office of the State Council has issued the specific 2009 implementation
               plan along with specific metrics. The plan promises RMB 850 billion
               (approximately USD 125 billion) of incremental government spending by 2011 to
               support the healthcare reform. There are still unresolved questions around the
               truly incremental part of the announced investment, especially as less than half
               of the planned funding will come directly from the central government. However,
               even under a conservative scenario, we believe government healthcare funding
               will grow at 20%+ a year over the next few years, providing a solid foundation for
               sustained growth in healthcare consumption in China (Exhibit 1).

               Two-thirds of this amount will go towards funding rural and urban insurance
               schemes (often described as “demand side funding”), while the government
               will allocate the remaining amount primarily to infrastructure, public hospital
               subsidy and public health (“supply side funding”). Such sizeable investments in
               infrastructure will also create opportunities in areas beyond pharmaceuticals,
               including medical devices/equipment, and hospital IT.




                  Exhibit Even under a conservative scenario, government healthcare
                Exhibit 1:1: Even under a conservative scenario, government healthcare
                funding will grow atat 20+% a year
                  funding will grow 20+% a year
                  Government healthcare spend
                  RMB billions


                                                                                                           33%
                                                                                                                       683
                                                                                                           533                         2/3 of the financing
                                                                   17%                                                                 will go to the demand
                   Moderate case1                                                               384
                                                                                    250                                                side
                                                             178         229
                                                  156                                                                                  Local government
                                                                                                                                       will shoulder 60% of
                                                                                                                                       the burden, while
                                                                                                                                       central will shoulder
                                                                                                                                       40%
                                                                                                           21%                         Focus is on rural and
                                                                                                                       500             “grassroots”
                   Conservative                                    +17%                                    420                         infrastructural
                   case2                                                                        341
                                                                         229        250                                                investment
                                                  156        178


                                                 2005         06         073         08         09          10      2011 E

                  1 Assuming RMB 850 bn budget is incremental to 2008 healthcare expenditure level
                  2 Assuming RMB 850 bn reform budget is incremental to the 2008 government appropriation to healthcare institutions (estimated as 137 bn in 2008)
                  3 Boost in spending in 2007 driven by significantly higher central government investment in insurance and hospital subsidies

                  SOURCE: MoH; analyst reports
8




    What the reform aims to change
    The Chinese government has prioritized five initiatives for the healthcare reform
    plan in the next three years:

    Expand basic medical insurance programs: The reform will provide wide
    medical insurance coverage to more than 90 per cent of Chinese people through
    Urban Employee Basic Medical Insurance (UEBMI) for urban workers and retirees,
    Urban Resident Basic Medical Insurance (URBMI) for urban residents and New
    Rural Cooperative Medical Scheme (NRCMS) for rural residents. Towards this goal,
    the government has set a specific target of 390 million people covered under the
    two urban insurance schemes by the end of 2009, as well as set a coverage goal for
    NRCMS at 90% or higher. In addition, the reform will raise premiums, as well as
    scope and percentage of reimbursable expenses; though in the near-term, patient
    out-of-pocket will continue to be a major source of healthcare expenditure (currently
    at approximately 45% of healthcare expenditure.

    Establish national essential drug system: The government will establish
    a national Essential Drug System (EDS) to meet basic needs for treatment and
    prevention of diseases and to ensure drug safety, quality and supply. Soon to
    be released, the Essential Drug List (EDL) will contain drugs covering all major
    therapeutic areas (from infectious disease to cancer), as well as Traditional
    Chinese Medicine (TCM). All government-owned primary healthcare institutions
    will be required to stock and prescribe EDS drugs. These drugs will also enjoy
    a higher reimbursement rate. Specifically, the government has set a goal of
    implementing EDS in 30% of urban communities and counties by December 2009,
    including the implementation of provincial-level centralized online public bidding
    and purchasing, and zero mark-up for EDS drugs.

    Develop primary healthcare services system: The reform aims to improve
    medical care at the grassroots level. In rural areas, it calls for the construction of
    2,000 county hospitals by 2011 to ensure that each county has at least one hospital
    that meets the county-level standards. In addition, plans call for constructing/
    refurbishing approximately 30,000 township hospitals. In urban areas, the
    government will construct about 3,700 urban Community Health Centers (CHCs)
    and 11,000 Community Healthcare Stations.
    While the government has not mandated compulsory primary care as a gatekeeper
    to more specialized services in hospitals, many local agencies are piloting
    incentives that encourage patients to visit primary care institutions. These include
    selling drugs to patients at low or no mark-up and higher reimbursement rates for
    drugs. To further promote use of its primary care facilities, the government will
    make significant investment to upgrade the quality of skills and infrastructure in
    the new primary care system, such as generalist training programs, and training
    linkages between Class III hospitals and county hospitals.

    Provide equal access to public health services for urban and rural
    residents: Part of the budget allocated to the healthcare reform will be used
    for funding basic public health services, including establishment of standardized
    health records, routine health screening, chronic disease management, infectious
    disease control, and an expanded national immunization program. Further, the
McKinsey Healthcare
China’s Healthcare Reform: Moving beyond reading of the tea leaves                                      9




               government will improve infrastructure for specialized healthcare institutions
               such as mental institutions, along with both pediatric and women’s centers.

               Accelerate public hospital reform: The Chinese government will launch
               pilot reforms in public hospitals that aim to reduce hospital reliance on margins
               from drug sales, eventually separating prescription of medicine from dispensing.
               Today, hospitals are dependent on revenues from drug margins to sustain their
               operations, but in the future, government will aim to offset this revenue loss
               through increased service fees and subsidies. Public hospital funding mechanism
               is arguably the core and central issue of China’s healthcare system today, however,
               given the various forces at work, we believe this will be the most difficult part of
               the overall reform and will take the longest to implement.



               What the reform will not change
               The reform will not play out as a large disruption that fundamentally alters the
               market overnight, but will change the nature of the market over time as policies
               are interpreted and piloted at provincial and local levels. In the mid term, patients
               will still have large out-of-pocket expenses, big hospitals and big cities will remain
               the core markets for MNC pharmacos, and companies will have to continue to
               address market access barriers at multiple levels.

               Significant out-of-pocket spending: While insurance subsidies will increase,
               coverage will be limited in the near term, in particular for outpatient treatment.
               For both URBMI and NRCMS, initial focus has been on covering inpatient
               treatment with co-pays that generally range from 30 to 65 per cent. Outpatient
               treatment coverage has often been excluded in the past, though recent government
               announcements suggest a push to fix this gap in coverage.

               Large urban cities will continue to be the core market: While much of the
               healthcare reform investment in insurance and infrastructure will focus on lower
               tier markets, there will also be significant investment to upgrade care provided in
               urban centers and expanded insurance for urban residents who are not covered by
               UEBMI. We believe lower tier markets will grow at a faster rate due to the influx
               of the new investment, but major urban centers will continue to experience strong
               growth in absolute value terms.

               Big hospitals will continue to be the key channel: Government has long
               targeted urban CHCs to lay the foundation for a primary care system and divert
               non-acute patient flow from over-stretched Class III hospitals. However, it also
               recognizes that it will take time for CHCs to play a big role as primary care centers.
               The withdrawal of an earlier policy enforcing mandatory CHC visits for initial
               diagnosis of common and chronic diseases to qualify for favorable reimbursement
               suggests recognition of the challenges involved, in particular on the upgrading/
               training of the medical staff working at CHCs. As a consequence, big hospitals will
               continue to be the key channel for pharmacos in the short term.

               Barriers at multiple levels will continue to constrain market access:
               Healthcare reform implementation is unlikely to change the complex, multi-tiered
               market access barriers that pharmacos need to navigate in China. Companies will
10




     have to continue to invest in ensuring hospital level listing, effective management
     of bidding/tenders at multiple levels, listing of recently launched drugs on
     reimbursement drug lists, and overall price management.

     As such, pharmacos need to ensure that they do not take their eyes off their
     strategy and priorities that have driven strong growth over the last few years.
     Companies will need to continue to expand and improve their sales force and
     marketing efforts (e.g., improved segmentation and targeting, lower turnover,
     better local marketing capabilities), enhance their capabilities and investments in
     market access (e.g., reimbursement listing, tendering and hospital listing), as well
     as upgrade their distribution and channel management practices.


     What are the uncertainties in the reform implementation?
     Despite the significant momentum in the last few months, there is still uncertainty
     in three areas: the “next level” of policy setting, pace of implementation, and how
     the implementation varies by geography. For example, in policy setting, while the
     final EDL list is expected soon, the government has yet to announce key details of
     the policy, including pricing, tendering mechanism, distribution, reimbursement
     levels, and compulsory usage proportions. In terms of implementation pace, while
     we may ascertain clues from the current implementation paths of provinces, it
     is not clear how aggressively government agencies will push at the central and
     local levels and how some reform levers will be prioritized over others. This will
     depend, to a large degree, on funding capacity at the local level as well as the
     availability and deployment of well-trained personnel to administer the various
     infrastructure roll-outs and reimbursement schemes. Finally, all this activity will
     vary tremendously by geography; both across city tiers as well as across provinces.

     These uncertainties often lead a company to defer actions until there is even
     greater clarity on implementation path. We believe this is a mistake. Given
     the complexity and heterogeneity of the healthcare reform implementation,
     uncertainties and confusion will continue to abound. Companies that wait for the
     proverbial dust to settle before acting will lag behind those who are comfortable in
     operating with a greater level of ambiguity and have already started to take actions
     to seize the new opportunities and mitigate new threats.
McKinsey Healthcare
China’s Healthcare Reform: Moving beyond reading of the tea leaves   11
12




     Implications of the reform:
     opportunities and threats
McKinsey Healthcare
China’s Healthcare Reform: Moving beyond reading of the tea leaves                                                                                       13




               Fundamentally, the various elements of reform should provide a positive stimulus
               to the growth of the pharmaceutical market in volume terms. Improvements
               in insurance as well as in care delivery will lead to higher diagnosis, treatment
               and compliance rates. Pricing picture, on the other hand, is less clear. While
               increased insurance will provide patients with the ability to afford higher-cost
               drugs, the implementation of EDS will shift the mix towards consumption of
               lower-cost drugs. In addition, there is high likelihood that the government
               will further tighten price control for a broader category of drugs as it gets more
               involved in providing insurance. Overall, the reform implementation is likely to
               further sharpen the division of the Chinese pharmaceutical market into two broad
               segments: “Innovative/Premium” segment drugs that are prescribed largely in
               urban hospitals, most on the Reimbursement Drug List (RDL) and thus partially
               reimbursed through UEBMI and URBMI; and “Volume” segment drugs that will
               be used largely in CHCs and rural primary care institutions, listed and supplied
               through the Essential Drug System (Exhibit 2).

               While specific opportunities and threats will be highly dependent on a given
               company’s product portfolio, competitive position, and risk appetite, there are
               four broad areas that we believe pharmacos should evaluate as they think about
               implications of the reform for their own business plans in China.

               EDS – a double-edged sword? Implementation of an effective EDS system
               has the potential to have major impact on the industry. While there are clearly
               uncertainties around the impact of EDS (in particular, on the size of the final
               molecule list and how quickly patient flow will increase outside big hospitals),
               companies would be wise to think through the potential risks to their business
               under several scenarios, as well as the opportunities to participate in the much
               broader “volume” segment of the market. Based on certain provisional lists that



                Exhibit 2: Reform will likely sharpen the division of the Chinese pharmaceu-
                 Exhibit 2: Reform will likely sharpen the division of the Chinese
                tical market into market into two broad segments
                 pharmaceutical two broad segments
                  Drug supply                        Medical insurance                  Medical provision
                                                                                                                              “Innovative/Premium”
                                                      Private insurance
                                                                                                                              segment drugs,
                                                                                                                              prescribed largely in
                   Non-reimbursable
                                                                                         Urban Hospitals                      urban hospitals,
                   products
                                                                                                                              partially reimbursed
                                                      BMI: Basic Medical                                                      through UEBMI and
                                                      Insurance for Urban                                                     URBMI
                                                      Employees and
                                                      Urban Residents


                   Products on RDL                                                       Urban CHCs
                                                                                                                              “Volume” segment
                                                                                                                              drugs, used largely in
                                                      RCMS: Rural Co-                                                         CHCs and rural
                                                      operative Medical                                                       primary care
                                                      Scheme                                                                  institutions, listed and
                                                                                                                              supplied through EDS
                                                                                         Rural healthcare
                   Products on EDS
                                                                                         institutions

                                                      Assistance


                 NOTE: RDL: Reimbursed Drug List, EDS: Essential Drug System, TCM: Traditional Chinese Medicine, BMI: Basic
                         Medical Insurance, RCMS: Rural Cooperative Medical Scheme, CHC: Community Health Center
14




     have been circulated, the exposure amongst leading pharmacos to drugs on EDS
     ranges from 20 per cent to 60 per cent of total sales (Exhibit 3). Pharmacos with
     a large portion of revenues from drugs that end up on EDS could see a significant
     loss of potential revenues if prescription volume shifts to CHCs, and they are not
     able to compete with low-priced products in the EDS tenders. Further, having a
     competing molecule on the EDS will impact competitive dynamics.
     Pharmacos with access to low cost manufacturing (ideally China-based) could
     consider competing in the volume segment, for their own but also for the broader
     list of EDS molecules. This would enable them to significantly expand access to
     the broader Chinese pharmaceutical market with a new business model that relies
     less on heavy investment in sales and marketing. However, pharmacos would
     need to manage the price risks as successive tenders may make the opportunity
     unsustainable, as well as ensure robust supply base, and scale-up Government
     Affairs (GA) and commercial capabilities to win provincial tenders.

     Focus on micro-markets to gain competitive differentiation in
     execution: Local reform implementation will further exaggerate local
     differences making “micro-market” execution a key competitive advantage.
     Many pharmacos have already implemented some form of regionalization model,
     often aggregating several provinces and placing critical capabilities in regional
     offices (e.g., local marketing, GA), and empowering them to tailor execution to
     local needs. Going forward, companies will need to further improve their ability
     to tailor their approach based on the local direction of reform implementation.
     Exhibit 4 shows an example of the different implementation paths taken by
     Zhejiang and Yunnan provinces in the last two years— Zhejiang has focused on
     drug pricing pilots and Yunnan on insurance coverage and hospital reform. We
     observe this variation across China as provinces have now collectively launched
     over 250 experimental healthcare reform pilots (Exhibit 5).
     Beyond province-level differences, we often see very different paths adopted by
     cities within a province. For example, in Guangdong province, the provincial
     capital Guangzhou is slow to develop new CHCs, while the other two major cities,


      Exhibit 3: EDS exposure amongst leading pharmacos ranges from 5-40%
     Exhibit 3: EDS exposure amongst leading pharmacos ranges from 5-40% of
     sales based on current provisional list list
      of sales based on current provisional

                                                                                                              DISGUISED MNCS
      MNCs with significant sales from EDS drugs, 2008


                    Proportion of total sales on EDS draft
                    Percent
                   45
                   40                                                                              G
                   35
                                                     J
                   30                                                                          I
                                                                                                   E
                   25
                                                 C
                   20                                              D
                   15                                    H
                                             F
                   10
                                   K   A
                    5
                    0
                        0     100      200   300     400     500   600   700   800   900 1,000 1,100 1,200
                                                                                     Sales of drugs on EDS
                                                                                               RMB millions

      SOURCE: MoH; Industry data
McKinsey Healthcare
China’s Healthcare Reform: Moving beyond reading of the tea leaves                                                                                             15




                Exhibit 4: Different implementation paths taken by Zhejiang and Yunnan
                 Exhibit 4: Different implementation paths taken by Zhejiang and Yunnan
                                      Zhejiang                                                         Yunnan
                                                                                                       Insurance coverage expanded to rural areas of
                                                                                                       Red River Hani and Yi ethnic group autono-
                    Insurance                                                                          mous region
                    coverage                                                                           Began to provide medical insurance and
                                                                                                       increase the basic living allowances standard to
                                                                                                       the disabled in urban areas
                                      Local prices adjusted for 21 different medicines
                                      sold
                                      Zhejiang Price Bureau disclosed maximum
                                      retail price for 1,002 Chinese traditional patent
                    Drug              medicines
                    pricing           Drug prices reduced at village and town clinics
                                      (including county clinics and community health
                                      service organizations)
                                      Maximum retail price disclosed for 161 drugs,
                                      with average price drop of 30%
                                      2 community hospitals in Ningbo began to                         Unified bidding and delivery of drugs
                                      pilot zero price markup                                          implemented in Xuanwei. New RCMS
                    Hospital                                                                           management office set up to approve prices
                    reform                                                                             Hospital pharmacy trusteeship
                                                                                                       implemented, including cancellation of 10%
                                                                                                       increase of drug price
                                      Strengthened promotion of maternal and
                    Public
                                      child healthcare, effectively prevented
                    health            giving birth at home

                 SOURCE: McKinsey reform pilot database; press search




                Exhibit 5: Reform implementation will be uneven due to differences in pace,
                Exhibit 5: Reform implementation will be uneven due to differences
                discipline and funding among provinces
                in pace, discipline and funding among provinces
                Large number of ongoing pilots (over 250) at varying levels of implementation; as of April 1, 2009                                  EXAMPLE

                  Summary of pilots                                 Location     Pilots                                 Location     Pilots

                               Number                               Shanxi       Online drug bidding                    Heilongjiang Hospital trusteeship
                  Category     of pilots Examples                   Gansu        DRG in selective                       Jilin        No deductibles for ER
                                                                                 diseases                               Liaoning     Special insurance
                  Coverage        6        Expand coverage
                                                                    Ningxia      Include TCM into                                    during unemployment
                                           of regional RDL
                                                                                 NRCMS
                                           Define drugs to be
                                           included in
                                           provincial RDL

                  Pricing        49        Price cutting                                                                Location     Pilots
                                           Hospital pharmacy
                                           trusteeship                                                                  Anhui        Cut average drug
                                                                                                                                     prices by 5%
                                           Online drug
                                           bidding                                                                      Jiangxi      Experiment DRG
                  Reimburse-     91        DRG system in                                                                             system
                  ment                     selective disease                                                            Zhejiang     Price-cut up to 30% for
                                           categories                                                                                161 drugs
                                           BMI expanded
                                           coverage
                                           BMI insurance
                                           upgrades
                                                                    Location     Pilots
                                                                                                                        Location     Pilots
                  Public         50        Expand vaccine           Sichuan      Online drug bidding
                  health                   portfolio for            Chongqing    DRG application in                     Hainan       Online drug bidding
                                           children                              selective hospitals                    Guangdong    NRCMS management
                  Public         47        Separation of                                                                             by Private insurance
                  hospital                                          Qinghai      Apply DRG in hos-
                                           prescribing and                                                              Shenzhen     Coverage of catas-
                  reform                                                         pitals covered by
                                           dispensing                                                                                trophic diseases
                                                                                 NRCMS



                SOURCE: McKinsey reform pilot database; press search
16




     Shenzhen and Dongguan, are much more advanced in this respect as well as
     implementing policies that help encourage patient flow to shift to CHCs (e.g., full
     funding support from government for zero mark-up on drugs in CHCs). Similarly,
     we see wide variation across cities in a given province on how they fund URBMI
     insurance programs, the way public hospital reform is being encouraged and how
     well prepared they are for implementation of EDS.
     Pharmacos can gain a competitive edge with a deep and granular understanding of
     local markets, and addressing the local market-specific dynamics by tailoring their
     activities (e.g., sales force targeting, GA priorities, tendering strategy) accordingly.
     We acknowledge there will always be a tension between keeping things simple
     and clear enough to ensure robust execution, and a tailored approach that,
     while appears good on paper, may be difficult to execute in China. Successful
     pharmacos in China will learn how to get this balance right as they adapt to the
     changing healthcare environment.

     Adapt your go-to-market model to follow the new patient f low: Efforts
     to encourage patients to seek primary care outside of big hospitals have accelerated
     over the past few years. While at an aggregate level the number of CHCs has
     grown quickly (Exhibit 6), the shift in patient flow has lagged behind. However,
     we have observed that in many cities (largely top tier cities with sufficient local
     funding), the additional investment in infrastructure, greater incentives for
     patients to visit CHCs and improvement in quality of medical staff is beginning
     to make a real impact on patient flow. In addition to the shift in top tier cities
     towards CHCs, the reform will also lead to faster growth of patient flow in lower-
     tier cities and rural areas compared to the top tier cities.
     For pharmacos with primary care/chronic therapy drugs, CHCs can be a
     complimentary channel to their existing hospital-focused sales efforts.



     Exhibit 6: Incentives to promote CHCs will further drive patients to seek
     Exhibit 6: Incentives to promote CHCs will further drive patients to seek
     primary care outside of big hospitals
     primary care outside of big hospitals

                                                                              Patient volume will be further driven by
       Number of CHCs has grown quickly                                       incentives to promote CHCs

       Number of CHCs                                                                             “Zero-markup” policy for
                                                                                Subsidize         drugs
                                                                                drug price
                                                                                                  CHCs sell to patients at
                                                                                                  hospital purchase price and
                                                               3,704                              get margin subsidy from local
                                    +32%
                                                      3,160                                       government
                                             2,077
                           1,128 1,382                                                            GP training at Class III
           692     753
                                                                                GP doctor         hospitals
                                                                                training
                                                                                                  Standardized GP training for
          2002      03       04       05       06       07     2008                               new medical school
                                                                                                  graduates


          Many CHCs in the past were a                                                            Upgrade CHC facility
                                                                                Facility
          ‘reclassification’ of Class I/II hospitals
                                                                                upgrade
          Latest reform announcement specified
          3,700 urban CHCs to be constructed
                                                                                                  Include CHCs into BMI
          between 2009 and 2011                                                 Insurance         treatment and reimbursement
                                                                                coverage



     SOURCE: MoH Hospital Database 2004-07, China Health Statistical Yearbook 2005-08
McKinsey Healthcare
China’s Healthcare Reform: Moving beyond reading of the tea leaves                                   17




               Recognizing the potential, some pharmacos have already started targeting CHCs
               for visits by their sales force. However, there is a real risk that CHCs will end
               up primarily prescribing low cost drugs. Under that scenario, for most MNC
               pharmacos, the CHC channel will, at best, be a distraction. Companies, therefore,
               need to objectively assess their portfolio and ability to compete in CHCs and lower
               tier cities before making a significant investment to target the ‘new channels’.

               Re-examine expanded set of acquisition options: Historically, MNC
               pharmacos have approached acquisitions of Chinese pharmaceutical companies
               with caution. Implementation of reform is leading many to reassess this position.
               From an industry structure perspective, the reform is likely to kick-start
               consolidation of the local pharmaceutical industry. If MNC pharmacos are truly
               interested in participating in the ‘volume’ segment of the market, a local company
               acquisition or partnership is likely essential. On top of providing access to an
               expanded set of molecules, it would provide a base for low cost manufacturing as
               well as potential advantages in the bidding process. In addition to the ‘volume’
               market, MNC pharmacos can substantially expand their presence in the broader
               branded generics segment through an acquisition that helps them overcome some
               of the access barriers (e.g., hospital listing of one local and one MNC brand per
               molecule).
               While the list of potential acquisition targets is long, the real challenge is in
               executing a deal that creates value for the pharmacos. Value destruction can
               happen through loss of sales revenue from aligning commercial practices,
               departure of critical talent in the acquired company, and quick erosion of inherent
               advantages of being a local company (e.g., low cost base, preference in local
               bidding). Companies need to go in with eyes wide open on the potential challenges
               and ensure they have the management team in place with sufficient experience in
               acquisitions in the Chinese context.
18




     Planning to win
McKinsey Healthcare
China’s Healthcare Reform: Moving beyond reading of the tea leaves                                    19




               As companies think through potential strategies to win in the evolving
               environment, they also need to pay close attention to capabilities. We would like
               to highlight four priorities that pharmacos should consider.

               Revisit portfolio/brand planning with a scenario based mindset:
               Given the uncertainties in the reform implementation, companies need to develop
               a handful of scenarios that frame their brand and portfolio planning, and test the
               robustness of their brand strategies under these scenarios. Let us illustrate this
               using an example for Hypertension therapies in China. Exhibit 7 shows three
               possible scenarios for the Hypertension market evolution driven by the major
               elements of reform. Companies can then quantify the likely changes in the market
               under each scenario and test the robustness of their existing strategy. Exhibit 8
               shows a possible output of this model indicating the core channels and geographies
               of the Hypertension market under each scenario. The important part is not the
               precise quantification of any particular scenario, but rather to make sure the
               brand team has thought through possible scenarios and has in place a systematic
               way to track how reform implementation is playing out, and has contingency plans
               prepared for alternate scenarios.

               Explore modified sales & distribution model to penetrate new
               channels: Profitably targeting the primary care channels (e.g., CHCs), and
               the fast-growing lower tier cities/rural areas will require companies to explore
               changes to their current sales and distribution model. Companies need to explore
               a less frequency-intensive model with greater focus on medical education events
               that target a larger number of physicians. The role of reps targeting the primary
               care channel may need to evolve to handle a larger number of products compared
               to the effectively single-product reps one sees today in large Chinese hospitals. In
               addition, pharmacos need to evolve their relationship with distributors to pursue
               the new channel opportunities. Success will require creating broader strategy
               partnerships with a small number of distributors who can effectively reach the
               lower tier cities/rural areas and provide strategic help in managing the tenders
               that are likely to be prevalent in the primary care channels.

               Revamp Government Affairs to manage increasingly complex market
               access challenges: Pharmacos should reevaluate the scale of resources they
               have in GA, the deployment across regions/cities, and the mandate they give to
               their GA organization. Historically, most GA organizations have been sub-scale
               compared to the size and complexity of the Chinese pharmaceutical market. To win
               in the evolving environment, companies will need a proactive GA organization that
               is able to systematically track and monitor the various elements of the reform, and
               is capable of helping the commercial organization draw the right insights about
               implications for the business. In addition, we believe there is a big opportunity
               for pharmacos to help shape how local authorities interpret and implement the
               various elements of the reform. However, to do this effectively will require an
               upgrade in both the size and the capabilities of the GA organization.

               Get internally organized to pursue business development/acquisition
               opportunities: All major pharmacos have a business development (BD)
               department in China and have spent significant energy in the past few years
               looking for deals. However, there has been very little to show for this effort. As
               companies take a fresh look at potential BD opportunities, a critical element before
20




     Exhibit 7: Example scenarios for market evolution of hypertension
     Exhibit 7: Example scenarios for market evolution of hypertension

                                                                                                                               ILLUSTRATIVE
                                                                                      Scenario
                                                           1                           2                                 3
                                                                             “EDS drives hyper-                “Lower tier drives
                                               “Limited impact”              tension treatment”                significant growth”

                      Accelerate shift                                        CHCs will account for             CHCs will account for
                                                                              increasing share of               increasing share of
                      of patient flow                                         patient volume                    patient volume
                      toward CHCs                 Healthcare reform
                                                  evolves at a slow
                                                  pace with limited           Major product listed on           Major product listed on
                                                  impact                      EDS and drives                    EDS and drives
                      Impact of EDS                                           increased hyper-                  increased hyper-tension
                                                  No elements of
                                                  reform become               tension treatment rates           treatment rates
         Key forces




                                                  mandatory in near-
                      Impact of lower             term                        Insurance coverage                Lower tier infra-
                                                                              and rural                         structure and cover-
                      tier coverage and                                       infrastructure evolve             age investment drive
                      infrastructure                                          slowly and have                   increase in lower tier
                                                                              limited impact                    market access and
                                                                                                                treatment affordability

                                                  Limited price cuts for      Price pressure for                Price pressure on
                      Increase price              anti-hypertension           EDS-listed product                EDS-listed products,
                      pressure                    products                                                      and gradual elimi-
                                                                                                                nation of innovative
                                                                                                                category




      Exhibit 8: Speed and emphasis of reform implementation will lead to
      Exhibit 8: Speed and emphasis of reform implementation will lead to
      different hypertension market development scenarios
      different hypertension market development scenarios
                                                                                                                                ILLUSTRATIVE

                                                                                  Core market       Secondary market        Limited/no presence



                                                                                     Scenario 2                   Scenario 3
                            Current anti-              Scenario 1                    “EDS drives hyper-           “Lower tier drives
                            hypertension market        “Limited impact”              tension treatment”           significant growth”


                 Rural
     Geography




                 Tier III


                 Tier II


                 Tier I


                            Class Class CHC/ Retail      Healthcare reform            EDS drives treatment          Lower tier infrastructure
                            III   II    Class I          evolves at a slow pace       affordability                 and coverage invest-
                                                         with limited impact          CHCs become the               ment drive increases in
                                   Channel                                                                          lower tier market access
                                                         No elements of reform        place for hypertension
                                                         become mandatory in          diagnosis, treatment          and treatment
                                                         near-term                    and refills                   affordability
                                                                                                                    EDS further drives
                                                                                                                    treatment affordability
McKinsey Healthcare
China’s Healthcare Reform: Moving beyond reading of the tea leaves                                      21




               getting started is to ensure solid internal alignment on the strategic rationale
               for pursuing a BD deal in China, as well as agreement on the parameters under
               which a deal is acceptable to the company (e.g., minority stake deals, level of effort
               required to bring commercial practices in line with global standards). In our
               experience, it is the lack of alignment between the local, regional and headquarters
               that leads to the premature end of many business development opportunities in
               China.

                                                            ***

               Healthcare reform will play a central role in the evolution of the pharmaceutical
               market. While there are open questions about exactly how implementation will
               happen at the local levels, no pharmaco with leading ambitions in China can
               ignore the potential opportunities and the threats that the reform presents for
               their business. Successful companies will find the right balance between a razor-
               sharp focus on near-term execution, and pursuing few strategic initiatives that
               help them capitalize on the reform.




               The authors would like to thank our colleagues in the McKinsey Greater China
               Healthcare practice for their contributions to this paper.

               For additional information contact:
               Ari Silverman (ari_silverman@mckinsey.com)
               Amie Chu (amie_chu@mckinsey.com)
               Yehong Zhang (yehong_zhang@mckinsey.com)
               Franck Le Deu (franck_le_deu@mckinsey.com)
               Yinuo Li (yinuo_li@mckinsey.com)
               Rajesh Parekh (rajesh_parekh@mckinsey.com)
22
McKinsey Greater China Healthcare
July 2009
Designed by Greater China Newmedia
Copyright © McKinsey & Company
www.mckinsey.com

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2009 China Healthcare Reform Moving Beyond Reading Of The Tea Leaves

  • 1. McKinsey Greater China Healthcare China’s Healthcare Reform: Moving beyond reading of the tea leaves
  • 2.
  • 3. McKinsey Greater China Healthcare July 2009 China’s Healthcare Reform: Moving beyond reading of the tea leaves Ari Silverman Amie Chu Yehong Zhang Franck Le Deu Yinuo Li Rajesh Parekh
  • 4. 4 Introduction
  • 5. McKinsey Healthcare China’s Healthcare Reform: Moving beyond reading of the tea leaves 5 China’s eagerly anticipated healthcare reform has finally been introduced, and it comes with the promise of a hefty investment into the healthcare system. As the reform implementation gets underway, executives at pharmaceutical companies (pharmacos) are trying to understand the specific implications for their own business and how they should think about changing their strategy/ plans for China. While there are open questions about the reform implementation at the local level, we believe the direction is now relatively clear, and pharmacos should move beyond the ‘reading of the tea leaves’ that has occupied China healthcare observers for the past few years. The reform points to some interesting new opportunities for pharmacos, as well as some real challenges to their core business. At the same time, reform will not change many of the fundamental drivers of the Chinese pharmaceutical market — and as such, it is important that executives at pharmacos do not get ‘distracted’ by the reform. As executives position their companies to succeed in the changing environment, they need to ensure that their organization stays focused on day-to-day execution and continue to build the core capabilities required for a winning pharma business in China1. In this paper, we lay out the key elements of the Chinese healthcare reform, identify four areas of opportunities and related threats for pharmacos, and outline how pharmacos can best plan to win in the new environment. 1 For more details please refer to the earlier publication from McKinsey & Company titled “Driving Growth in Turbulent Chinese Pharmaceutical Market – Part 2”.
  • 6. 6 Key elements of the reform
  • 7. McKinsey Healthcare China’s Healthcare Reform: Moving beyond reading of the tea leaves 7 In early 2009, China’s State Council announced the long-awaited and much- debated healthcare reform. The initial announcements have been followed by a serious of policy documents that describe in greater detail how the various agencies plan to carry out the implementation. Most recently in late July, the General Office of the State Council has issued the specific 2009 implementation plan along with specific metrics. The plan promises RMB 850 billion (approximately USD 125 billion) of incremental government spending by 2011 to support the healthcare reform. There are still unresolved questions around the truly incremental part of the announced investment, especially as less than half of the planned funding will come directly from the central government. However, even under a conservative scenario, we believe government healthcare funding will grow at 20%+ a year over the next few years, providing a solid foundation for sustained growth in healthcare consumption in China (Exhibit 1). Two-thirds of this amount will go towards funding rural and urban insurance schemes (often described as “demand side funding”), while the government will allocate the remaining amount primarily to infrastructure, public hospital subsidy and public health (“supply side funding”). Such sizeable investments in infrastructure will also create opportunities in areas beyond pharmaceuticals, including medical devices/equipment, and hospital IT. Exhibit Even under a conservative scenario, government healthcare Exhibit 1:1: Even under a conservative scenario, government healthcare funding will grow atat 20+% a year funding will grow 20+% a year Government healthcare spend RMB billions 33% 683 533 2/3 of the financing 17% will go to the demand Moderate case1 384 250 side 178 229 156 Local government will shoulder 60% of the burden, while central will shoulder 40% 21% Focus is on rural and 500 “grassroots” Conservative +17% 420 infrastructural case2 341 229 250 investment 156 178 2005 06 073 08 09 10 2011 E 1 Assuming RMB 850 bn budget is incremental to 2008 healthcare expenditure level 2 Assuming RMB 850 bn reform budget is incremental to the 2008 government appropriation to healthcare institutions (estimated as 137 bn in 2008) 3 Boost in spending in 2007 driven by significantly higher central government investment in insurance and hospital subsidies SOURCE: MoH; analyst reports
  • 8. 8 What the reform aims to change The Chinese government has prioritized five initiatives for the healthcare reform plan in the next three years: Expand basic medical insurance programs: The reform will provide wide medical insurance coverage to more than 90 per cent of Chinese people through Urban Employee Basic Medical Insurance (UEBMI) for urban workers and retirees, Urban Resident Basic Medical Insurance (URBMI) for urban residents and New Rural Cooperative Medical Scheme (NRCMS) for rural residents. Towards this goal, the government has set a specific target of 390 million people covered under the two urban insurance schemes by the end of 2009, as well as set a coverage goal for NRCMS at 90% or higher. In addition, the reform will raise premiums, as well as scope and percentage of reimbursable expenses; though in the near-term, patient out-of-pocket will continue to be a major source of healthcare expenditure (currently at approximately 45% of healthcare expenditure. Establish national essential drug system: The government will establish a national Essential Drug System (EDS) to meet basic needs for treatment and prevention of diseases and to ensure drug safety, quality and supply. Soon to be released, the Essential Drug List (EDL) will contain drugs covering all major therapeutic areas (from infectious disease to cancer), as well as Traditional Chinese Medicine (TCM). All government-owned primary healthcare institutions will be required to stock and prescribe EDS drugs. These drugs will also enjoy a higher reimbursement rate. Specifically, the government has set a goal of implementing EDS in 30% of urban communities and counties by December 2009, including the implementation of provincial-level centralized online public bidding and purchasing, and zero mark-up for EDS drugs. Develop primary healthcare services system: The reform aims to improve medical care at the grassroots level. In rural areas, it calls for the construction of 2,000 county hospitals by 2011 to ensure that each county has at least one hospital that meets the county-level standards. In addition, plans call for constructing/ refurbishing approximately 30,000 township hospitals. In urban areas, the government will construct about 3,700 urban Community Health Centers (CHCs) and 11,000 Community Healthcare Stations. While the government has not mandated compulsory primary care as a gatekeeper to more specialized services in hospitals, many local agencies are piloting incentives that encourage patients to visit primary care institutions. These include selling drugs to patients at low or no mark-up and higher reimbursement rates for drugs. To further promote use of its primary care facilities, the government will make significant investment to upgrade the quality of skills and infrastructure in the new primary care system, such as generalist training programs, and training linkages between Class III hospitals and county hospitals. Provide equal access to public health services for urban and rural residents: Part of the budget allocated to the healthcare reform will be used for funding basic public health services, including establishment of standardized health records, routine health screening, chronic disease management, infectious disease control, and an expanded national immunization program. Further, the
  • 9. McKinsey Healthcare China’s Healthcare Reform: Moving beyond reading of the tea leaves 9 government will improve infrastructure for specialized healthcare institutions such as mental institutions, along with both pediatric and women’s centers. Accelerate public hospital reform: The Chinese government will launch pilot reforms in public hospitals that aim to reduce hospital reliance on margins from drug sales, eventually separating prescription of medicine from dispensing. Today, hospitals are dependent on revenues from drug margins to sustain their operations, but in the future, government will aim to offset this revenue loss through increased service fees and subsidies. Public hospital funding mechanism is arguably the core and central issue of China’s healthcare system today, however, given the various forces at work, we believe this will be the most difficult part of the overall reform and will take the longest to implement. What the reform will not change The reform will not play out as a large disruption that fundamentally alters the market overnight, but will change the nature of the market over time as policies are interpreted and piloted at provincial and local levels. In the mid term, patients will still have large out-of-pocket expenses, big hospitals and big cities will remain the core markets for MNC pharmacos, and companies will have to continue to address market access barriers at multiple levels. Significant out-of-pocket spending: While insurance subsidies will increase, coverage will be limited in the near term, in particular for outpatient treatment. For both URBMI and NRCMS, initial focus has been on covering inpatient treatment with co-pays that generally range from 30 to 65 per cent. Outpatient treatment coverage has often been excluded in the past, though recent government announcements suggest a push to fix this gap in coverage. Large urban cities will continue to be the core market: While much of the healthcare reform investment in insurance and infrastructure will focus on lower tier markets, there will also be significant investment to upgrade care provided in urban centers and expanded insurance for urban residents who are not covered by UEBMI. We believe lower tier markets will grow at a faster rate due to the influx of the new investment, but major urban centers will continue to experience strong growth in absolute value terms. Big hospitals will continue to be the key channel: Government has long targeted urban CHCs to lay the foundation for a primary care system and divert non-acute patient flow from over-stretched Class III hospitals. However, it also recognizes that it will take time for CHCs to play a big role as primary care centers. The withdrawal of an earlier policy enforcing mandatory CHC visits for initial diagnosis of common and chronic diseases to qualify for favorable reimbursement suggests recognition of the challenges involved, in particular on the upgrading/ training of the medical staff working at CHCs. As a consequence, big hospitals will continue to be the key channel for pharmacos in the short term. Barriers at multiple levels will continue to constrain market access: Healthcare reform implementation is unlikely to change the complex, multi-tiered market access barriers that pharmacos need to navigate in China. Companies will
  • 10. 10 have to continue to invest in ensuring hospital level listing, effective management of bidding/tenders at multiple levels, listing of recently launched drugs on reimbursement drug lists, and overall price management. As such, pharmacos need to ensure that they do not take their eyes off their strategy and priorities that have driven strong growth over the last few years. Companies will need to continue to expand and improve their sales force and marketing efforts (e.g., improved segmentation and targeting, lower turnover, better local marketing capabilities), enhance their capabilities and investments in market access (e.g., reimbursement listing, tendering and hospital listing), as well as upgrade their distribution and channel management practices. What are the uncertainties in the reform implementation? Despite the significant momentum in the last few months, there is still uncertainty in three areas: the “next level” of policy setting, pace of implementation, and how the implementation varies by geography. For example, in policy setting, while the final EDL list is expected soon, the government has yet to announce key details of the policy, including pricing, tendering mechanism, distribution, reimbursement levels, and compulsory usage proportions. In terms of implementation pace, while we may ascertain clues from the current implementation paths of provinces, it is not clear how aggressively government agencies will push at the central and local levels and how some reform levers will be prioritized over others. This will depend, to a large degree, on funding capacity at the local level as well as the availability and deployment of well-trained personnel to administer the various infrastructure roll-outs and reimbursement schemes. Finally, all this activity will vary tremendously by geography; both across city tiers as well as across provinces. These uncertainties often lead a company to defer actions until there is even greater clarity on implementation path. We believe this is a mistake. Given the complexity and heterogeneity of the healthcare reform implementation, uncertainties and confusion will continue to abound. Companies that wait for the proverbial dust to settle before acting will lag behind those who are comfortable in operating with a greater level of ambiguity and have already started to take actions to seize the new opportunities and mitigate new threats.
  • 11. McKinsey Healthcare China’s Healthcare Reform: Moving beyond reading of the tea leaves 11
  • 12. 12 Implications of the reform: opportunities and threats
  • 13. McKinsey Healthcare China’s Healthcare Reform: Moving beyond reading of the tea leaves 13 Fundamentally, the various elements of reform should provide a positive stimulus to the growth of the pharmaceutical market in volume terms. Improvements in insurance as well as in care delivery will lead to higher diagnosis, treatment and compliance rates. Pricing picture, on the other hand, is less clear. While increased insurance will provide patients with the ability to afford higher-cost drugs, the implementation of EDS will shift the mix towards consumption of lower-cost drugs. In addition, there is high likelihood that the government will further tighten price control for a broader category of drugs as it gets more involved in providing insurance. Overall, the reform implementation is likely to further sharpen the division of the Chinese pharmaceutical market into two broad segments: “Innovative/Premium” segment drugs that are prescribed largely in urban hospitals, most on the Reimbursement Drug List (RDL) and thus partially reimbursed through UEBMI and URBMI; and “Volume” segment drugs that will be used largely in CHCs and rural primary care institutions, listed and supplied through the Essential Drug System (Exhibit 2). While specific opportunities and threats will be highly dependent on a given company’s product portfolio, competitive position, and risk appetite, there are four broad areas that we believe pharmacos should evaluate as they think about implications of the reform for their own business plans in China. EDS – a double-edged sword? Implementation of an effective EDS system has the potential to have major impact on the industry. While there are clearly uncertainties around the impact of EDS (in particular, on the size of the final molecule list and how quickly patient flow will increase outside big hospitals), companies would be wise to think through the potential risks to their business under several scenarios, as well as the opportunities to participate in the much broader “volume” segment of the market. Based on certain provisional lists that Exhibit 2: Reform will likely sharpen the division of the Chinese pharmaceu- Exhibit 2: Reform will likely sharpen the division of the Chinese tical market into market into two broad segments pharmaceutical two broad segments Drug supply Medical insurance Medical provision “Innovative/Premium” Private insurance segment drugs, prescribed largely in Non-reimbursable Urban Hospitals urban hospitals, products partially reimbursed BMI: Basic Medical through UEBMI and Insurance for Urban URBMI Employees and Urban Residents Products on RDL Urban CHCs “Volume” segment drugs, used largely in RCMS: Rural Co- CHCs and rural operative Medical primary care Scheme institutions, listed and supplied through EDS Rural healthcare Products on EDS institutions Assistance NOTE: RDL: Reimbursed Drug List, EDS: Essential Drug System, TCM: Traditional Chinese Medicine, BMI: Basic Medical Insurance, RCMS: Rural Cooperative Medical Scheme, CHC: Community Health Center
  • 14. 14 have been circulated, the exposure amongst leading pharmacos to drugs on EDS ranges from 20 per cent to 60 per cent of total sales (Exhibit 3). Pharmacos with a large portion of revenues from drugs that end up on EDS could see a significant loss of potential revenues if prescription volume shifts to CHCs, and they are not able to compete with low-priced products in the EDS tenders. Further, having a competing molecule on the EDS will impact competitive dynamics. Pharmacos with access to low cost manufacturing (ideally China-based) could consider competing in the volume segment, for their own but also for the broader list of EDS molecules. This would enable them to significantly expand access to the broader Chinese pharmaceutical market with a new business model that relies less on heavy investment in sales and marketing. However, pharmacos would need to manage the price risks as successive tenders may make the opportunity unsustainable, as well as ensure robust supply base, and scale-up Government Affairs (GA) and commercial capabilities to win provincial tenders. Focus on micro-markets to gain competitive differentiation in execution: Local reform implementation will further exaggerate local differences making “micro-market” execution a key competitive advantage. Many pharmacos have already implemented some form of regionalization model, often aggregating several provinces and placing critical capabilities in regional offices (e.g., local marketing, GA), and empowering them to tailor execution to local needs. Going forward, companies will need to further improve their ability to tailor their approach based on the local direction of reform implementation. Exhibit 4 shows an example of the different implementation paths taken by Zhejiang and Yunnan provinces in the last two years— Zhejiang has focused on drug pricing pilots and Yunnan on insurance coverage and hospital reform. We observe this variation across China as provinces have now collectively launched over 250 experimental healthcare reform pilots (Exhibit 5). Beyond province-level differences, we often see very different paths adopted by cities within a province. For example, in Guangdong province, the provincial capital Guangzhou is slow to develop new CHCs, while the other two major cities, Exhibit 3: EDS exposure amongst leading pharmacos ranges from 5-40% Exhibit 3: EDS exposure amongst leading pharmacos ranges from 5-40% of sales based on current provisional list list of sales based on current provisional DISGUISED MNCS MNCs with significant sales from EDS drugs, 2008 Proportion of total sales on EDS draft Percent 45 40 G 35 J 30 I E 25 C 20 D 15 H F 10 K A 5 0 0 100 200 300 400 500 600 700 800 900 1,000 1,100 1,200 Sales of drugs on EDS RMB millions SOURCE: MoH; Industry data
  • 15. McKinsey Healthcare China’s Healthcare Reform: Moving beyond reading of the tea leaves 15 Exhibit 4: Different implementation paths taken by Zhejiang and Yunnan Exhibit 4: Different implementation paths taken by Zhejiang and Yunnan Zhejiang Yunnan Insurance coverage expanded to rural areas of Red River Hani and Yi ethnic group autono- Insurance mous region coverage Began to provide medical insurance and increase the basic living allowances standard to the disabled in urban areas Local prices adjusted for 21 different medicines sold Zhejiang Price Bureau disclosed maximum retail price for 1,002 Chinese traditional patent Drug medicines pricing Drug prices reduced at village and town clinics (including county clinics and community health service organizations) Maximum retail price disclosed for 161 drugs, with average price drop of 30% 2 community hospitals in Ningbo began to Unified bidding and delivery of drugs pilot zero price markup implemented in Xuanwei. New RCMS Hospital management office set up to approve prices reform Hospital pharmacy trusteeship implemented, including cancellation of 10% increase of drug price Strengthened promotion of maternal and Public child healthcare, effectively prevented health giving birth at home SOURCE: McKinsey reform pilot database; press search Exhibit 5: Reform implementation will be uneven due to differences in pace, Exhibit 5: Reform implementation will be uneven due to differences discipline and funding among provinces in pace, discipline and funding among provinces Large number of ongoing pilots (over 250) at varying levels of implementation; as of April 1, 2009 EXAMPLE Summary of pilots Location Pilots Location Pilots Number Shanxi Online drug bidding Heilongjiang Hospital trusteeship Category of pilots Examples Gansu DRG in selective Jilin No deductibles for ER diseases Liaoning Special insurance Coverage 6 Expand coverage Ningxia Include TCM into during unemployment of regional RDL NRCMS Define drugs to be included in provincial RDL Pricing 49 Price cutting Location Pilots Hospital pharmacy trusteeship Anhui Cut average drug prices by 5% Online drug bidding Jiangxi Experiment DRG Reimburse- 91 DRG system in system ment selective disease Zhejiang Price-cut up to 30% for categories 161 drugs BMI expanded coverage BMI insurance upgrades Location Pilots Location Pilots Public 50 Expand vaccine Sichuan Online drug bidding health portfolio for Chongqing DRG application in Hainan Online drug bidding children selective hospitals Guangdong NRCMS management Public 47 Separation of by Private insurance hospital Qinghai Apply DRG in hos- prescribing and Shenzhen Coverage of catas- reform pitals covered by dispensing trophic diseases NRCMS SOURCE: McKinsey reform pilot database; press search
  • 16. 16 Shenzhen and Dongguan, are much more advanced in this respect as well as implementing policies that help encourage patient flow to shift to CHCs (e.g., full funding support from government for zero mark-up on drugs in CHCs). Similarly, we see wide variation across cities in a given province on how they fund URBMI insurance programs, the way public hospital reform is being encouraged and how well prepared they are for implementation of EDS. Pharmacos can gain a competitive edge with a deep and granular understanding of local markets, and addressing the local market-specific dynamics by tailoring their activities (e.g., sales force targeting, GA priorities, tendering strategy) accordingly. We acknowledge there will always be a tension between keeping things simple and clear enough to ensure robust execution, and a tailored approach that, while appears good on paper, may be difficult to execute in China. Successful pharmacos in China will learn how to get this balance right as they adapt to the changing healthcare environment. Adapt your go-to-market model to follow the new patient f low: Efforts to encourage patients to seek primary care outside of big hospitals have accelerated over the past few years. While at an aggregate level the number of CHCs has grown quickly (Exhibit 6), the shift in patient flow has lagged behind. However, we have observed that in many cities (largely top tier cities with sufficient local funding), the additional investment in infrastructure, greater incentives for patients to visit CHCs and improvement in quality of medical staff is beginning to make a real impact on patient flow. In addition to the shift in top tier cities towards CHCs, the reform will also lead to faster growth of patient flow in lower- tier cities and rural areas compared to the top tier cities. For pharmacos with primary care/chronic therapy drugs, CHCs can be a complimentary channel to their existing hospital-focused sales efforts. Exhibit 6: Incentives to promote CHCs will further drive patients to seek Exhibit 6: Incentives to promote CHCs will further drive patients to seek primary care outside of big hospitals primary care outside of big hospitals Patient volume will be further driven by Number of CHCs has grown quickly incentives to promote CHCs Number of CHCs “Zero-markup” policy for Subsidize drugs drug price CHCs sell to patients at hospital purchase price and 3,704 get margin subsidy from local +32% 3,160 government 2,077 1,128 1,382 GP training at Class III 692 753 GP doctor hospitals training Standardized GP training for 2002 03 04 05 06 07 2008 new medical school graduates Many CHCs in the past were a Upgrade CHC facility Facility ‘reclassification’ of Class I/II hospitals upgrade Latest reform announcement specified 3,700 urban CHCs to be constructed Include CHCs into BMI between 2009 and 2011 Insurance treatment and reimbursement coverage SOURCE: MoH Hospital Database 2004-07, China Health Statistical Yearbook 2005-08
  • 17. McKinsey Healthcare China’s Healthcare Reform: Moving beyond reading of the tea leaves 17 Recognizing the potential, some pharmacos have already started targeting CHCs for visits by their sales force. However, there is a real risk that CHCs will end up primarily prescribing low cost drugs. Under that scenario, for most MNC pharmacos, the CHC channel will, at best, be a distraction. Companies, therefore, need to objectively assess their portfolio and ability to compete in CHCs and lower tier cities before making a significant investment to target the ‘new channels’. Re-examine expanded set of acquisition options: Historically, MNC pharmacos have approached acquisitions of Chinese pharmaceutical companies with caution. Implementation of reform is leading many to reassess this position. From an industry structure perspective, the reform is likely to kick-start consolidation of the local pharmaceutical industry. If MNC pharmacos are truly interested in participating in the ‘volume’ segment of the market, a local company acquisition or partnership is likely essential. On top of providing access to an expanded set of molecules, it would provide a base for low cost manufacturing as well as potential advantages in the bidding process. In addition to the ‘volume’ market, MNC pharmacos can substantially expand their presence in the broader branded generics segment through an acquisition that helps them overcome some of the access barriers (e.g., hospital listing of one local and one MNC brand per molecule). While the list of potential acquisition targets is long, the real challenge is in executing a deal that creates value for the pharmacos. Value destruction can happen through loss of sales revenue from aligning commercial practices, departure of critical talent in the acquired company, and quick erosion of inherent advantages of being a local company (e.g., low cost base, preference in local bidding). Companies need to go in with eyes wide open on the potential challenges and ensure they have the management team in place with sufficient experience in acquisitions in the Chinese context.
  • 18. 18 Planning to win
  • 19. McKinsey Healthcare China’s Healthcare Reform: Moving beyond reading of the tea leaves 19 As companies think through potential strategies to win in the evolving environment, they also need to pay close attention to capabilities. We would like to highlight four priorities that pharmacos should consider. Revisit portfolio/brand planning with a scenario based mindset: Given the uncertainties in the reform implementation, companies need to develop a handful of scenarios that frame their brand and portfolio planning, and test the robustness of their brand strategies under these scenarios. Let us illustrate this using an example for Hypertension therapies in China. Exhibit 7 shows three possible scenarios for the Hypertension market evolution driven by the major elements of reform. Companies can then quantify the likely changes in the market under each scenario and test the robustness of their existing strategy. Exhibit 8 shows a possible output of this model indicating the core channels and geographies of the Hypertension market under each scenario. The important part is not the precise quantification of any particular scenario, but rather to make sure the brand team has thought through possible scenarios and has in place a systematic way to track how reform implementation is playing out, and has contingency plans prepared for alternate scenarios. Explore modified sales & distribution model to penetrate new channels: Profitably targeting the primary care channels (e.g., CHCs), and the fast-growing lower tier cities/rural areas will require companies to explore changes to their current sales and distribution model. Companies need to explore a less frequency-intensive model with greater focus on medical education events that target a larger number of physicians. The role of reps targeting the primary care channel may need to evolve to handle a larger number of products compared to the effectively single-product reps one sees today in large Chinese hospitals. In addition, pharmacos need to evolve their relationship with distributors to pursue the new channel opportunities. Success will require creating broader strategy partnerships with a small number of distributors who can effectively reach the lower tier cities/rural areas and provide strategic help in managing the tenders that are likely to be prevalent in the primary care channels. Revamp Government Affairs to manage increasingly complex market access challenges: Pharmacos should reevaluate the scale of resources they have in GA, the deployment across regions/cities, and the mandate they give to their GA organization. Historically, most GA organizations have been sub-scale compared to the size and complexity of the Chinese pharmaceutical market. To win in the evolving environment, companies will need a proactive GA organization that is able to systematically track and monitor the various elements of the reform, and is capable of helping the commercial organization draw the right insights about implications for the business. In addition, we believe there is a big opportunity for pharmacos to help shape how local authorities interpret and implement the various elements of the reform. However, to do this effectively will require an upgrade in both the size and the capabilities of the GA organization. Get internally organized to pursue business development/acquisition opportunities: All major pharmacos have a business development (BD) department in China and have spent significant energy in the past few years looking for deals. However, there has been very little to show for this effort. As companies take a fresh look at potential BD opportunities, a critical element before
  • 20. 20 Exhibit 7: Example scenarios for market evolution of hypertension Exhibit 7: Example scenarios for market evolution of hypertension ILLUSTRATIVE Scenario 1 2 3 “EDS drives hyper- “Lower tier drives “Limited impact” tension treatment” significant growth” Accelerate shift CHCs will account for CHCs will account for increasing share of increasing share of of patient flow patient volume patient volume toward CHCs Healthcare reform evolves at a slow pace with limited Major product listed on Major product listed on impact EDS and drives EDS and drives Impact of EDS increased hyper- increased hyper-tension No elements of reform become tension treatment rates treatment rates Key forces mandatory in near- Impact of lower term Insurance coverage Lower tier infra- and rural structure and cover- tier coverage and infrastructure evolve age investment drive infrastructure slowly and have increase in lower tier limited impact market access and treatment affordability Limited price cuts for Price pressure for Price pressure on Increase price anti-hypertension EDS-listed product EDS-listed products, pressure products and gradual elimi- nation of innovative category Exhibit 8: Speed and emphasis of reform implementation will lead to Exhibit 8: Speed and emphasis of reform implementation will lead to different hypertension market development scenarios different hypertension market development scenarios ILLUSTRATIVE Core market Secondary market Limited/no presence Scenario 2 Scenario 3 Current anti- Scenario 1 “EDS drives hyper- “Lower tier drives hypertension market “Limited impact” tension treatment” significant growth” Rural Geography Tier III Tier II Tier I Class Class CHC/ Retail Healthcare reform EDS drives treatment Lower tier infrastructure III II Class I evolves at a slow pace affordability and coverage invest- with limited impact CHCs become the ment drive increases in Channel lower tier market access No elements of reform place for hypertension become mandatory in diagnosis, treatment and treatment near-term and refills affordability EDS further drives treatment affordability
  • 21. McKinsey Healthcare China’s Healthcare Reform: Moving beyond reading of the tea leaves 21 getting started is to ensure solid internal alignment on the strategic rationale for pursuing a BD deal in China, as well as agreement on the parameters under which a deal is acceptable to the company (e.g., minority stake deals, level of effort required to bring commercial practices in line with global standards). In our experience, it is the lack of alignment between the local, regional and headquarters that leads to the premature end of many business development opportunities in China. *** Healthcare reform will play a central role in the evolution of the pharmaceutical market. While there are open questions about exactly how implementation will happen at the local levels, no pharmaco with leading ambitions in China can ignore the potential opportunities and the threats that the reform presents for their business. Successful companies will find the right balance between a razor- sharp focus on near-term execution, and pursuing few strategic initiatives that help them capitalize on the reform. The authors would like to thank our colleagues in the McKinsey Greater China Healthcare practice for their contributions to this paper. For additional information contact: Ari Silverman (ari_silverman@mckinsey.com) Amie Chu (amie_chu@mckinsey.com) Yehong Zhang (yehong_zhang@mckinsey.com) Franck Le Deu (franck_le_deu@mckinsey.com) Yinuo Li (yinuo_li@mckinsey.com) Rajesh Parekh (rajesh_parekh@mckinsey.com)
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  • 24. McKinsey Greater China Healthcare July 2009 Designed by Greater China Newmedia Copyright © McKinsey & Company www.mckinsey.com