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Yes, but wait 'til you taste one, dearie.
Like to try one? Go on.
Go on, have a bite.




Attempted Assassination
Intentional Suicide                         Intentional Homicide




                                              Accidental Overdose
Drug Identification and
      Toxicology
      Pick Your Poison!
Accidental Overdose
•   On February 9, 2007 it was determined that
    tabloid celebrity Anna Nicole Smith had died
    from an accidental overdose of prescription
    drugs, rather than as the result of foul play or
    illegal drug use.

•   How did the medical examiner know which
    drugs Smith had taken?

•   How was it determined that the overdose was
    accidental rather than intentional?

•   IT’S ALL ABOUT TOXICOLOGY!
What is Toxicology?

• Toxicology is the study of the affects that
  toxic chemicals have on the body.

• A toxicologist is originally presented with
  body fluids and/or organs and is normally
  requested to examine them for the
  presence of drugs and poisons.
Forensic Toxicology
• Forensic    toxicology is used to aid in
    medical and legal investigations of
    poisoning, death, and drug use.
•   Involved in Drug Identification
Common Chemicals,
Toxins, and Poisons!
• Illegal drugs
• Prescription drugs
• Alcohol
• Poisons
• Metals
Controlled Substances
• Drugs or chemical            • Include:
  compounds whose
  manufacture, distribution,
                                   • Hallucinogens
  possession, and use is           • Narcotics
  regulated by the legal
  system
                                   • Stimulants
                                   • Anabolic
                                     Steroids
                                  • Depressants
Signs and Symptoms
• For Homework: Count off by 5s
• Each of you will fill out ONE section of the
  Controlled substances signs and symptoms
  CHART
• Instead of Journal tomorrow you will get
  into your groups and present your findings
  to the rest of the class.
          • Resources to use: Textbook,
            Internet, other books, etc.
How are these
    substances identified?
• Without supportive evidence, such as the
  victim’s symptoms, a postmortem
  pathological examination, or an examination
  of the victim’s personal effects, the
  toxicologist is forced to use general screening
  procedures with the hope of narrowing
  thousands of possibilities to one.
Common Chemical
     Tests
• Gas-liquid chromatography
• Immunoassay
• Thin-layer chromatography
• Spot Tests

         Educational Requirements: Bachelor’s in Biology or
         Chemistry
         After 3 yrs. in the field American Board of Forensic
         Toxicology offers certification
Challenges of a Forensic
      Toxicologist
• A toxicologist is not dealing with drugs at
    the concentration levels found in powders
    and pills, having been dissipated and
    distributed throughout the body.
•   Furthermore, the body is an active
    chemistry laboratory as few substances
    enter and completely leave the body in the
    same chemical state.
Now YOU will Try it!



URINE OVER YOUR
     HEAD!
      LAB

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00 poisons

  • 1. Yes, but wait 'til you taste one, dearie. Like to try one? Go on. Go on, have a bite. Attempted Assassination Intentional Suicide Intentional Homicide Accidental Overdose
  • 2. Drug Identification and Toxicology Pick Your Poison!
  • 3. Accidental Overdose • On February 9, 2007 it was determined that tabloid celebrity Anna Nicole Smith had died from an accidental overdose of prescription drugs, rather than as the result of foul play or illegal drug use. • How did the medical examiner know which drugs Smith had taken? • How was it determined that the overdose was accidental rather than intentional? • IT’S ALL ABOUT TOXICOLOGY!
  • 4. What is Toxicology? • Toxicology is the study of the affects that toxic chemicals have on the body. • A toxicologist is originally presented with body fluids and/or organs and is normally requested to examine them for the presence of drugs and poisons.
  • 5. Forensic Toxicology • Forensic toxicology is used to aid in medical and legal investigations of poisoning, death, and drug use. • Involved in Drug Identification
  • 6. Common Chemicals, Toxins, and Poisons! • Illegal drugs • Prescription drugs • Alcohol • Poisons • Metals
  • 7. Controlled Substances • Drugs or chemical • Include: compounds whose manufacture, distribution, • Hallucinogens possession, and use is • Narcotics regulated by the legal system • Stimulants • Anabolic Steroids • Depressants
  • 8. Signs and Symptoms • For Homework: Count off by 5s • Each of you will fill out ONE section of the Controlled substances signs and symptoms CHART • Instead of Journal tomorrow you will get into your groups and present your findings to the rest of the class. • Resources to use: Textbook, Internet, other books, etc.
  • 9. How are these substances identified? • Without supportive evidence, such as the victim’s symptoms, a postmortem pathological examination, or an examination of the victim’s personal effects, the toxicologist is forced to use general screening procedures with the hope of narrowing thousands of possibilities to one.
  • 10. Common Chemical Tests • Gas-liquid chromatography • Immunoassay • Thin-layer chromatography • Spot Tests Educational Requirements: Bachelor’s in Biology or Chemistry After 3 yrs. in the field American Board of Forensic Toxicology offers certification
  • 11. Challenges of a Forensic Toxicologist • A toxicologist is not dealing with drugs at the concentration levels found in powders and pills, having been dissipated and distributed throughout the body. • Furthermore, the body is an active chemistry laboratory as few substances enter and completely leave the body in the same chemical state.
  • 12. Now YOU will Try it! URINE OVER YOUR HEAD! LAB