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Diabetic Microvascular Complications
- 1. Diabetic Microvascular Complications Mathew John MD, DM, DNB Consultant Endocrinologist
- 2. Microvascular complication MICROVASCULAR COMPLICATIONS Retinopathy Neuropathy Nephropathy Cardiomyopathy Cheiroarhropathy Dermopathy
- 6. UKPDS results of Intensive therapy Risk reduction vs. conventional therapy
- 13. Mild non proliferative retinopathy Flame shaped hemorrhages Microaneursms Dot & Blot hemorrhages
- 14. Severe non proliferative retinopathy
- 16. Clinically Significant Macular edema www.retinalphysician.com/archive%5C2009%5CJan
- 28. Progression of nephropathy Normal Microalbuminuria 2% per annum Clinical Nephropathy > 300 mg/gm 2% per annum < 30 mg/gm 30-300 mg/gm
- 44. Road to ulcer Bunions Clawed toes Abnormal toe nails
- 47. The Extent of Diabetic Neuropathy
Hinweis der Redaktion
- 50 % of all patients with type 1 DM and PDR and > 10 years duration have concomitant proteinuria
- Measurement of the albumin-to-creatinine ratio in a random spot collection OR 2) 24-h collection with creatinine, allowing the simultaneous measurement of creatinine clearance; and OR 3) timed (e.g., 4-h or overnight) collection .
- In the Kumamoto Study, a reduction in the conversion from micro- to macroalbuminuria was observed with intensive treatment
- It often is considered that the clinical expression of diabetic neuropathy is the tip of the iceberg. Patients presenting with symptoms, particularly numbness and pain, represent only a small percentage of patients with neuropathy. Clinical examination may detect asymptomatic neuropathy in another 30% of patients. Further sophisticated testing, including quantitative sensory testing and electrophysiologic testing, such as nerve conduction velocity, might pick up abnormalities in another 30% to 40% of patients who cannot be detected on clinical examination, but such testing is rarely, if ever, done in clinical practice on asymptomatic patients. The clinician usually can differentiate the symptoms of neuropathy from other symptoms based on the pattern of complaints and physical findings. Occasionally, electrophysiologic testing may be required.