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Training Programme
              on
Fluorosis Control Programme
           Presented By
        Dibyendu Dutta
           Consultant
  Fluorosis Control Programme
            BANKURA
    Mob. No- 8900336639
Fluorosis Control Programme : Importance
Importance of this Programme in this District
i)    Fluorosis is a crippled disease. It makes immobilized the patient
      day by day. Where as no exact mortality is found but its makes the
      people crippled and some cases painful. With out mobility
     people can not earn and life going unhealthy ,
     stopped.
ii) Fluorosis is a chronic disease. Its affect the people slowly and makes
preliminary symptoms -> dental fluorosis -> skeletal fluorosis -> spinal
compression ->Crippled disorder. As it is due to make by slowly ingestion
of fluoride(more then 1.5 PPM) in drinking water , its severity is very
much higher.
iii) Affected people :
      Bankura : 90,702.
      Affected Village: 205
      Affected Habitaion: 1005
      Affected Tube well: 778
      Fluoride range: up to 12.69 ppm water.
Fluorosis Control Programme : Status of West
Bengal
Fluorosis Control Programme : Status of
Bankura
 Persons suffers from Fluorosis in India : 6 Million
                                 (Dr. Raja Reddy , NIN ,
  Hyderabad)
 Persons suffers from Fluorosis in West Bengal: 2.20 Lakh
 Persons Suffers from Fluorosis in Bankura: 90,742
 Current Status of Fluorosis In Bankura District
GIS Mapping of fluorosis endemic Block
Fluorosis Control Programme : Magnitude
of the problem
 West Bengal are worst affected from fluorosis. In Bankura
  District Fluorosis Unit had already been find that :
 Water –fluoride level various from: 1.00 PPM – 12.69 PPM
  (Machatora,Simlapal)
 Patient Blood-fluoride level: Sujit Gulimajhi 22/M
  (Jamda,Simlapal)0.89 ppm Jenu Valgaum. Severe Dental
  Fluorosis. Joint Pain and Back Pain.
   Highest Urine fluoride level: Bulu Bedia ,Kamladanga
    11.25 PPM .
           In all these States, the drinking water has high fluoride content but the information
about the various food items and industrial emission having high fluoride level is not available.
        Permissible limit for fluoride, as per BIS, is 1 ppm in
    drinking water.
Fluorosis Control Programme : Magnitude
of the problem
Dental fluorosis at Bankura District
Skeletal Fluorosis at Bankura District
Fluorosis Control Programme :


Surveillance Methodology and
Promotion of the Fluorosis
Control Programme
Assessment of the Problem


  Under the National Programme for Prevention and Control
  of Fluorosis, the district laboratory is established/
  strengthened for confirmation of fluorosis cases, the
  district cell under district nodal officer is created, staffed
  with consultant and field investigators and funds are
  provided for mobility support for undertaking community
  based surveillance. The surveillance would also provide the
  database for impact assessment of the programme. The
  case definitions, sampling procedure and survey
  methodology are as under:
(Dr. Pasha,National Consultant)
A : Case Definition
  Suspect Case:
  Dental Fluorosis:




 Any case with a history of residing in an endemic area
 along with one or both of the followings:
      Chalky white teeth
      yellow brown/dark brown bands
A : Case Definition
Skeletal Fluorosis

Any case with a history of residing in an
 endemic area along with one or more of the
 following:
 Severe pain and stiffness in neck and back bone.
    (Patient has to turn the whole body towards that side
    to see)
   Severe pain and stiffness in joints.
   Severe pain and rigidity in the hip region ( pelvic
    girdle)
   Knock knee/ Bow leg
   Inability to squat
   Ugly gait and posture
A : Case Definition
Non skeletal Fluorosis


Any case with a history of residing in an
endemic area along with one or more of
the followings
      Gastro - intestinal problems: Consistent abdominal pain,
       intermittent diarrhea/Constipation, blood in stool
      Neurological manifestations: Nervousness & depression,
       tingling sensation in fingers and toes, excessive thirst and
       tendency to urinate frequently (Polydipsia and polyuria)
      Muscular manifestations: Muscle weakness & stiffness, pain in
       the muscle and loss of muscle power.
A : Case Definition
   Confirmed Case:
 Any suspect case with one or more of the
 followings:

 Any suspect case with high level of fluoride in urine
  (>1ppm).
 Any suspect case with interossius membrane
  calcification in the fore arm confirmed by X-ray.
B - Sampling procedure
    The information on fluorosis endemic areas along with
    fluoride level in the drinking water sources is to be
    obtained from Public Health Engineering Department
    (PHED) of respective endemic states.
         Fluoride level in all the drinking water sources is to be
          estimated by PHED.
         Based on the level of fluoride content, the villages will be
          stratified in the following 3 strata as under:
                 Strata                        Fluoride Level

                 I                                     1 - 3 ppm
                  II                                    3.1 – 5 ppm
                 III                                    > 5 ppm
Sampling procedure

   For prevalence of fluorosis cases, 10% villages of each
    strata will be selected randomly. If number of villages
    is up to 20, then all the villages will be surveyed. If
    number of villages is more than 20, then 10% of
    villages from each strata (at least 20 villages in total)
    will be surveyed.
   All the children in the age group of 6 to 11 years from
    the primary school (3rd to 5th standard) in the
    selected villages of the district will be surveyed for
    prevalence of dental fluorosis.
   Survey for skeletal and non-skeletal fluorosis cases
    would also be carried out in 20 households of
    randomly selected villages of the district where dental
    fluorosis is prevalent in school children.
C - Survey Methodology
 Details of survey for dental fluorosis in school children
  will be collected on predesigned proforma and for skeletal
  and non-skeletal fluorosis cases in villages would be
  conducted by trained investigators.
 The information on demographic profile, dietary intake,
  drinking water source and clinical manifestations of
  fluorosis in the suspected member (s) of the family will be
  collected in the predesigned format.
 Urine samples from fluorosis suspected cases will be
  collected for confirmation.
 The suspected cases would be confirmed for interossius
  membrane calcification in the fore arm by X-ray and
  fluoride level in urine (>1ppm).
Survey Methodology



Analysis of urine sample


  Sample Collection:
      15 ml of spot urine sample of the suspected cases
       will be collected in 25ml of plastic screw capped
       bottles.

      Put 1 - 2 drops of toluene on urine samples to make
       a complete layer as preservative.

      Each sample should be properly labeled with
       number and relevant details.
Survey Methodology

 Transportation of samples:

      Urine samples should be sent to district laboratory
       within a weeks time.

      Samples can be kept at room temperature at district
       laboratory if not being analyzed immediately.

   *Report should be sent to State Nodal officer
   on the predesigned Performa with a copy to
   Adviser (Nutrition), DGHS, New Delhi
    (Dr. Pasha,National Consultant)
Guidelines for Training
Training in a programme is a key step for its successful
implementation.
A pool of trainers will be generated at state/ district level
to provide training of different category of health care
providers at different level.
1. Training of Trainers
2.   Medical Officer
3.   Laboratory Technicians
4.   Paramedical
5.   Training of Health Workers, ASHA and AWWs
6.   Policy makers &
7.   Advocacy PRIs & VHSC& Teachers
Guidelines for Comprehensive
        Management of Fluorosis Cases

     Guidelines for Comprehensive Management
     of Flurosis Cases are:


              Early Detection &
              Prompt Intervention
Comprehensive Management
Early Detection:-
 It includes physical and radiological examination. During physical
    examination the cases are to be identified as suspected cases and
    confirmed cases. The symptoms of the suspected cases are as
    follows:-
   Dental changes – chalky white tooth with mottled appearance
   Pain & stiffness of peripheral joints
   Deformities of lower limb
   The confirmation of the cases shall be undertaken by following
    methods:
      Physical examination
      Radiological examination
              X-ray of forearm (AP view)
              X-ray of most affected part (AP & lateral views)

 Laboratory tests
          Urine analysis for fluoride level
          Blood analysis for fluoride level
          Analysis of drinking water for fluoride level
Comprehensive Management

 Prompt Intervention
  The Prompt Intervention is to be planned in the
  following manner:
    Health education
    Preventive measures
    Treatment
    Rehabilitation
Media Plan for Prevention and Control of
                Fluorosis
  The IEC Plan covering awareness generation and to bring
  behavioural communication changes at the community level in
  affected districts are very important in order to prevent and
  control fluorosis in the community. For this there is a need:
 to educate community about adverse health effects of drinking water
  with high level of fluoride,
 to educate the community about the safe drinking water sources in
  their habitation and rain water harvesting measures to be adopted.
 to educate about the benefits of Nutritional interventions.
 The district level media team would be entrusted with the job of
  advocating with the various functionaries of the district including
  community level workers namely, ASHA, AWW, school teachers,
  Panchayats, etc.
IEC Plan for Preventionand Control of
               Fluorosis
Do’s and Don’ts in relation to Nutrition
intervention in fluorosis


     Do’s                         Don’ts
     Calcium rich food            Black tea
    Milk, Milk products           Black/Rock salt
     Green leafy vegetable        Tobacco
                                         Supari
                                  Fluoridated tooth paste
     Vitamin C rich food
       Citrus fruits
     Green leafy vegetables

      Iron rich food
             Green leafy vegetables
      Guava, Banana, Brinjal
Programme Stacture and its Overview (NPPCF, Bnakura)

        The Adviser (Nutrition)                    The District Consultant
        MH&FW.New Delhi.India                        (NPPCF.Bankura)


     The National Consultant(NPPCF)                The District Lab Tech
                                                        (NPPCF)
                  The DHS
                SH&FW. W.B.
                                                      Field Workers
          The Add. DHS(PH&CD)                            (NPPCF)
      SH&FW. Swasthya Bhaban. Kol-91.
                   W.B.


                                  The Dy.DHS(PH&CD)
                                        and
           The ADHS(MPHWS) & SPO (NPPCF)Swasthya Bhaban. Kol-91. W.B.


                                 The CMOH
                  and District Programme Officer. (NPPCF)

                                      The Dy. CMOH-II
                              and District Nodal Officer(NPPCF)
Performance and duties done by District Fluorosis Control
Unit.Bankura.

                           • Successful implementation of this National
                             Programme
                           • Monitoring the programme by consulting all its
 The District Consultant     Stake-Holders/Concern Persons under direct
                             control of District Programme officers/District
                             Nodal Officers.


                           • Management and safe operating of Lab.
                             Instrument.
  The District Lab Tech    • Make ready report , Testing of Collected sample and as
                             necessary he should also visit the endemic village for blood
                             collection under supervision of his consultant and direct
                             control od district officers.


                           • Field Survey , sample collection and make ready
                             report.
                           • Make data-entry of patient line listing (As per state
   Field Investigators       needed)
                           • This National Programme will be successful if all district
                             programme holders wants.
Promotion of the Programme
1.   Involvement should be made of Block level
2.   BPHN/PHN supervise the screening of fluorosis cases and collection
     of sample made by ANM staffs and ASHA at grass-root level.
3.   Sample should be sent to District Lab. for testing.
4.   Block Data Entry Operator should Collect the data / report and make
     compile report to sent at District.
5.   District should compile the report from blocks and sent to state
     authority. And also arrange screening camp + Sample collection +
     Drug Distribution + IEC Camp etc.
6.   District fluorosis unit also maintain the overall programme under
     direct control of District Programme Officer and District Nodal
     Officer
7.   District Programme Officer and District Nodal Officer supervise the
     all programme.
THANK YOU
Table of Content:                                PART-A
1. Current Status of Fluorosis in World View
2. Current Status of fluorosis in India
3. Current Status of Fluorosis in West Bengal
4. Current Status of Fluorosis in Bankura.
       4.1 Data Sheet of fluorosis endemicity
       4.2 GIS Mapping of fluorosis endemic Block
5. Availability of fluoride-free water scheme by District
administration
6. Programme Overview (NPPCF, Bnakura)
7.Performance and duties done by District Fluorosis Control
Unit.Bankura.
1. Current Status of Fluorosis in World View
Fluorosis is public health problem in 25 countries around the world.(DARK
AREAS)
2. Current             Status of fluorosis in India
               Jammu &
               Kashmir
               7
                                                                                  No of affected
                  Himachal Pradesh                    Arunachal                    District 204 (21
            Punjab
                              Delhi                   Pradesh                      States /UT)
            82
             Haryana
                              31
               63
      Rajastha                           Sikkim
      n
                       Uttar Pradesh
                       22
                                                       Assam
                                                             Nagaland             people affected, 62
                                     Bihar             9
      100.0
 Gujarat                             15
                                                           Manipur
                                                Tripura Mizoram
                                                                                   million ( 6 million
                Madhya Pradesh                                                     children)
 95
                36                           West Bengal
                                  Orissa     22
         Maharashtra
         31
                                  56
                                                   70-100 % Districts affected
                                                                                  Causative factor,
                   Andhra Pradesh
                                                   40-70 % Districts affected
                                                                                   excess consumption
         Karnataka 70
         67                                       10-40 % Districts affected       of fluoride through
                                                   <10% Districts affected         drinking water
               Tamil Nadu                          Endemicity not known            (>1.0ppm) and diet.
               28
      Kerala                                                 Andaman
      21                                                     Nicobar



       Source:A Treatise on Fluorosis by Dr. A.K. Susheela
. Current Status of Fluorosis in West Bengal
4.0 Current Status of Fluorosis in Bankura.
endemicity
     Persons suffers from Fluorosis in India : 6 Million
                                 (Dr. Raja Reddy , NIN , Hyderabad)
     Persons suffers from Fluorosis in West Bengal: 2.20 Lakh
     Persons Suffers from Fluorosis in Bankura: 90,742
     Current Status of Fluorosis In Bankura District

                                                  Affected Pop.




                                                                                                                                                       Affected Pop.
                                                                                                Affected Vill.
Tot. Blocks




                                                                  Tot. Village
                                                                  in Bankura




                                                                                                                                          Habitation
                                                                                                                             Habitation



                                                                                                                                          (Approx)


                                                                                                                                                         (Approx)
                                                                                                                 Affected.
                                     Tot. Pop.




                                                                                    Tot. Pop.
                          Affected




                                                                                                                                           Affected
                           Block
              Pop.




                                                                                                                   Pop.


                                                                                                                               Tot.
      22      31,92,695     15        20,21,341   90,742            3832         31,92,695                271     90,742     7778          1005
                                                                                                                                                           90,742
4.2 GIS Mapping of fluorosis endemic Block
Bnakura)
           The Adviser (Nutrition)   The District Consultant
           MH&FW.New Delhi.India       (NPPCF.Bankura)
                      I
               The National
             Consultant(NPPCF)

                                           The District Lab
                                                Tech
                                              (NPPCF)
                    The DHS
                SH&FW. W.B.

                                            Field Workers
                   The Add.                    (NPPCF)
                 DHS(PH&CD)
                   SH&FW.
                   Swasthya
                Bhaban. Kol-91.
                     W.B.
                     The
                ADHS(MPHWS)
                    & SPO
               (NPPCF)Swasthy
               a Bhaban. Kol-91.
                     W.B.

                  The CMOH
                  and District
                  Programme
                Officer. (NPPCF)


                The Dy. CMOH-
                       II
                 and District
                     Nodal
                Officer(NPPCF)
7.Performance and duties done by District Fluorosis Control
Unit.Bankura.
                           • Successful implementation of this National
                             Programme
                           • Monitoring the programme by consulting all its
 The District Consultant     Stake-Holders/Concern Persons under direct
                             control of District Programme officers/District
                             Nodal Officers.


                           • Management and safe operating of Lab.
                             Instrument.
  The District Lab Tech    • Make ready report , Testing of Collected sample and as
                             necessary he should also visit the endemic village for blood
                             collection under supervision of his consultant and direct
                             control od district officers.


                           • Field Survey , sample collection and make ready
                             report.
                           • Make data-entry of patient line listing (As per state
   Field Investigators       needed)
                           • This National Programme will be successful if all district
                             programme holders wants.
Table of Content:                          PART - B
1.   Fluorosis and fluoride
        1.1 Fluoride
        1.2 Pathophysiology of Fluorosis
2.    Dental fluorosis
3.    Skeletal Fluorosis
4.    Non-Skeletal Manifestation
5.    Laboratory Support
6.    Prevention and Control Measure
7.    Roll of PHED & DH&FWS. Bankura
5.    Current Research on fluorosis
Fluorosis and fluoride
     1.1 Fluoride
1.2 Pathophysiology of Fluorosis
           Ingestion of fluoride causes decrease in ionised calcium.

          This hypocalcemia leads to changes in internal milieu of the body to maintain the
    calcium levels and leads to secondary hyperparathyroidism.


           The increased parathyroid hormone causes increased activity of Osteoclasts in bone
    by activating membrane bound 3'5' Cyclic AMP.

           This increased osteoclastic activity causes, increases in citric acid and lactic acid
    release from ruffled border of osteoclasts. This causes increase in hydrogen ion
    concentration, and hence lysis of lysosomes.


          Release of lysosomal enzymes viz. acid protease, collagenase, hyaluronic acid in
    bone and other tissues of the body which catalyzes the reactions favoring the
    depolymerization of the glycoprotein of bone and of cartilage. This causes breakdown of
    hydroxyproline, which is responsible for stabilization of collagen triple helix.

           As the protein polymer desegregates and dissolves, the mineral-binding capacity is
    also reduced and calcium is liberated, which helps in maintaining the serum calcium level.
    As a result the solubility of hydroxyappetite crystals also increases, causing its breakdown
    along with reduced laying down of collagen by reducing Hydroxylation of proline and
    lysine.


           This event simultaneously led to the elevation of the serum mucoprotein or
    polysaccharide levels. The net result of degradation of ground substance in, bones and
    other calcified tissues like teeth leads to symptoms of Fluorosis like, delayed eruption of
    teeth, dental Fluorosis, clinical Fluorosis, premature aging etc
Dental fluorosis
Normal:
The enamel surface is smooth, glossy
and usually a pale creamy white in
color.




Mild: The white opacity of the
enamel of the teeth is more
extensive, but covers less than
50% of the tooth surface .
Moderate:The enamel surface of the teeth
shows marked wear and tear with brown stain
and is frequently a disfiguring feature .




Severe: The enamel surface is badly
affected and hypoplasia is so marked that
the general form of the tooth may be
affected. There are pitted/worn out areas
and widespread brownish discoloration
with the teeth often having a corroded
appearance.
Types of skeletal fluorosis - I
Genu valgum (KNOCK KNEES)
Legs are bowed inwards in the standing
position. The bowing usually occurs at
or around the knee, and when standing
with knees together, the feet are far
apart.




Genu Varum
Legs are bowed outwards in the
standing position. The bowing
usually occurs at or around the
knee. When standing with the feet
together, the knees remains far
apart.
Types of skeletal fluorosis - II
Kyphosis: – Forward bending of spine.
Fixed and rigid thoracic cage as well as
spinal cord compression occur




                                           Anterioposterior
                                           bowing of tibia
Types of skeletal fluorosis - III



Paraplegia: Spinal cord
compression due to
osteosclerosis with
paraplegia as a result
of endemic skeletal
fluorosis
NON SKELETAL MANIFESTATIONS

 Tingling sensation in fingers and toes
 Excessive thirst
 Polydypsia and polyurea
 Nervousness & Depression
Laboratory Support
Table of Content:                                          PART - C
1. Diagramatic view of Programme holder. NPPCF
2.Work Structure of National Programme for Prevention and
Control of Fluorosis
       2.1 District level planning of programme outlet.
       2.2 Duties of Block Medical Officer of Health at District(BMOH)
       2.3 Duties of Block Public Health Nurse(BPHN)
       2.4 Duties of Supervisor at Gram Panchyaet Level.
       2.5 Importance of ASHA at next phase of the
programme.

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Presentation regarding Fluorosis

  • 1. Training Programme on Fluorosis Control Programme Presented By Dibyendu Dutta Consultant Fluorosis Control Programme BANKURA Mob. No- 8900336639
  • 2. Fluorosis Control Programme : Importance Importance of this Programme in this District i) Fluorosis is a crippled disease. It makes immobilized the patient day by day. Where as no exact mortality is found but its makes the people crippled and some cases painful. With out mobility people can not earn and life going unhealthy , stopped. ii) Fluorosis is a chronic disease. Its affect the people slowly and makes preliminary symptoms -> dental fluorosis -> skeletal fluorosis -> spinal compression ->Crippled disorder. As it is due to make by slowly ingestion of fluoride(more then 1.5 PPM) in drinking water , its severity is very much higher. iii) Affected people : Bankura : 90,702. Affected Village: 205 Affected Habitaion: 1005 Affected Tube well: 778 Fluoride range: up to 12.69 ppm water.
  • 3. Fluorosis Control Programme : Status of West Bengal
  • 4. Fluorosis Control Programme : Status of Bankura  Persons suffers from Fluorosis in India : 6 Million  (Dr. Raja Reddy , NIN , Hyderabad)  Persons suffers from Fluorosis in West Bengal: 2.20 Lakh  Persons Suffers from Fluorosis in Bankura: 90,742  Current Status of Fluorosis In Bankura District
  • 5. GIS Mapping of fluorosis endemic Block
  • 6. Fluorosis Control Programme : Magnitude of the problem  West Bengal are worst affected from fluorosis. In Bankura District Fluorosis Unit had already been find that :  Water –fluoride level various from: 1.00 PPM – 12.69 PPM (Machatora,Simlapal)  Patient Blood-fluoride level: Sujit Gulimajhi 22/M (Jamda,Simlapal)0.89 ppm Jenu Valgaum. Severe Dental Fluorosis. Joint Pain and Back Pain. Highest Urine fluoride level: Bulu Bedia ,Kamladanga 11.25 PPM . In all these States, the drinking water has high fluoride content but the information about the various food items and industrial emission having high fluoride level is not available.  Permissible limit for fluoride, as per BIS, is 1 ppm in drinking water.
  • 7.
  • 8. Fluorosis Control Programme : Magnitude of the problem
  • 9. Dental fluorosis at Bankura District
  • 10. Skeletal Fluorosis at Bankura District
  • 11. Fluorosis Control Programme : Surveillance Methodology and Promotion of the Fluorosis Control Programme
  • 12. Assessment of the Problem Under the National Programme for Prevention and Control of Fluorosis, the district laboratory is established/ strengthened for confirmation of fluorosis cases, the district cell under district nodal officer is created, staffed with consultant and field investigators and funds are provided for mobility support for undertaking community based surveillance. The surveillance would also provide the database for impact assessment of the programme. The case definitions, sampling procedure and survey methodology are as under: (Dr. Pasha,National Consultant)
  • 13. A : Case Definition  Suspect Case:  Dental Fluorosis: Any case with a history of residing in an endemic area along with one or both of the followings:  Chalky white teeth  yellow brown/dark brown bands
  • 14. A : Case Definition Skeletal Fluorosis Any case with a history of residing in an endemic area along with one or more of the following:  Severe pain and stiffness in neck and back bone. (Patient has to turn the whole body towards that side to see)  Severe pain and stiffness in joints.  Severe pain and rigidity in the hip region ( pelvic girdle)  Knock knee/ Bow leg  Inability to squat  Ugly gait and posture
  • 15. A : Case Definition Non skeletal Fluorosis Any case with a history of residing in an endemic area along with one or more of the followings  Gastro - intestinal problems: Consistent abdominal pain, intermittent diarrhea/Constipation, blood in stool  Neurological manifestations: Nervousness & depression, tingling sensation in fingers and toes, excessive thirst and tendency to urinate frequently (Polydipsia and polyuria)  Muscular manifestations: Muscle weakness & stiffness, pain in the muscle and loss of muscle power.
  • 16. A : Case Definition  Confirmed Case: Any suspect case with one or more of the followings:  Any suspect case with high level of fluoride in urine (>1ppm).  Any suspect case with interossius membrane calcification in the fore arm confirmed by X-ray.
  • 17. B - Sampling procedure The information on fluorosis endemic areas along with fluoride level in the drinking water sources is to be obtained from Public Health Engineering Department (PHED) of respective endemic states.  Fluoride level in all the drinking water sources is to be estimated by PHED.  Based on the level of fluoride content, the villages will be stratified in the following 3 strata as under: Strata Fluoride Level  I 1 - 3 ppm II 3.1 – 5 ppm III > 5 ppm
  • 18. Sampling procedure  For prevalence of fluorosis cases, 10% villages of each strata will be selected randomly. If number of villages is up to 20, then all the villages will be surveyed. If number of villages is more than 20, then 10% of villages from each strata (at least 20 villages in total) will be surveyed.  All the children in the age group of 6 to 11 years from the primary school (3rd to 5th standard) in the selected villages of the district will be surveyed for prevalence of dental fluorosis.  Survey for skeletal and non-skeletal fluorosis cases would also be carried out in 20 households of randomly selected villages of the district where dental fluorosis is prevalent in school children.
  • 19. C - Survey Methodology  Details of survey for dental fluorosis in school children will be collected on predesigned proforma and for skeletal and non-skeletal fluorosis cases in villages would be conducted by trained investigators.  The information on demographic profile, dietary intake, drinking water source and clinical manifestations of fluorosis in the suspected member (s) of the family will be collected in the predesigned format.  Urine samples from fluorosis suspected cases will be collected for confirmation.  The suspected cases would be confirmed for interossius membrane calcification in the fore arm by X-ray and fluoride level in urine (>1ppm).
  • 20. Survey Methodology Analysis of urine sample Sample Collection:  15 ml of spot urine sample of the suspected cases will be collected in 25ml of plastic screw capped bottles.  Put 1 - 2 drops of toluene on urine samples to make a complete layer as preservative.  Each sample should be properly labeled with number and relevant details.
  • 21. Survey Methodology  Transportation of samples:  Urine samples should be sent to district laboratory within a weeks time.  Samples can be kept at room temperature at district laboratory if not being analyzed immediately. *Report should be sent to State Nodal officer on the predesigned Performa with a copy to Adviser (Nutrition), DGHS, New Delhi (Dr. Pasha,National Consultant)
  • 22. Guidelines for Training Training in a programme is a key step for its successful implementation. A pool of trainers will be generated at state/ district level to provide training of different category of health care providers at different level. 1. Training of Trainers 2. Medical Officer 3. Laboratory Technicians 4. Paramedical 5. Training of Health Workers, ASHA and AWWs 6. Policy makers & 7. Advocacy PRIs & VHSC& Teachers
  • 23. Guidelines for Comprehensive Management of Fluorosis Cases  Guidelines for Comprehensive Management of Flurosis Cases are:  Early Detection &  Prompt Intervention
  • 24. Comprehensive Management Early Detection:-  It includes physical and radiological examination. During physical examination the cases are to be identified as suspected cases and confirmed cases. The symptoms of the suspected cases are as follows:-  Dental changes – chalky white tooth with mottled appearance  Pain & stiffness of peripheral joints  Deformities of lower limb  The confirmation of the cases shall be undertaken by following methods:  Physical examination  Radiological examination  X-ray of forearm (AP view)  X-ray of most affected part (AP & lateral views)  Laboratory tests  Urine analysis for fluoride level  Blood analysis for fluoride level  Analysis of drinking water for fluoride level
  • 25. Comprehensive Management  Prompt Intervention The Prompt Intervention is to be planned in the following manner:  Health education  Preventive measures  Treatment  Rehabilitation
  • 26. Media Plan for Prevention and Control of Fluorosis The IEC Plan covering awareness generation and to bring behavioural communication changes at the community level in affected districts are very important in order to prevent and control fluorosis in the community. For this there is a need:  to educate community about adverse health effects of drinking water with high level of fluoride,  to educate the community about the safe drinking water sources in their habitation and rain water harvesting measures to be adopted.  to educate about the benefits of Nutritional interventions.  The district level media team would be entrusted with the job of advocating with the various functionaries of the district including community level workers namely, ASHA, AWW, school teachers, Panchayats, etc.
  • 27. IEC Plan for Preventionand Control of Fluorosis
  • 28.
  • 29. Do’s and Don’ts in relation to Nutrition intervention in fluorosis  Do’s Don’ts Calcium rich food Black tea Milk, Milk products Black/Rock salt Green leafy vegetable Tobacco Supari Fluoridated tooth paste Vitamin C rich food Citrus fruits Green leafy vegetables Iron rich food Green leafy vegetables Guava, Banana, Brinjal
  • 30.
  • 31. Programme Stacture and its Overview (NPPCF, Bnakura) The Adviser (Nutrition) The District Consultant MH&FW.New Delhi.India (NPPCF.Bankura) The National Consultant(NPPCF) The District Lab Tech (NPPCF) The DHS SH&FW. W.B. Field Workers The Add. DHS(PH&CD) (NPPCF) SH&FW. Swasthya Bhaban. Kol-91. W.B. The Dy.DHS(PH&CD) and The ADHS(MPHWS) & SPO (NPPCF)Swasthya Bhaban. Kol-91. W.B. The CMOH and District Programme Officer. (NPPCF) The Dy. CMOH-II and District Nodal Officer(NPPCF)
  • 32. Performance and duties done by District Fluorosis Control Unit.Bankura. • Successful implementation of this National Programme • Monitoring the programme by consulting all its The District Consultant Stake-Holders/Concern Persons under direct control of District Programme officers/District Nodal Officers. • Management and safe operating of Lab. Instrument. The District Lab Tech • Make ready report , Testing of Collected sample and as necessary he should also visit the endemic village for blood collection under supervision of his consultant and direct control od district officers. • Field Survey , sample collection and make ready report. • Make data-entry of patient line listing (As per state Field Investigators needed) • This National Programme will be successful if all district programme holders wants.
  • 33. Promotion of the Programme 1. Involvement should be made of Block level 2. BPHN/PHN supervise the screening of fluorosis cases and collection of sample made by ANM staffs and ASHA at grass-root level. 3. Sample should be sent to District Lab. for testing. 4. Block Data Entry Operator should Collect the data / report and make compile report to sent at District. 5. District should compile the report from blocks and sent to state authority. And also arrange screening camp + Sample collection + Drug Distribution + IEC Camp etc. 6. District fluorosis unit also maintain the overall programme under direct control of District Programme Officer and District Nodal Officer 7. District Programme Officer and District Nodal Officer supervise the all programme.
  • 35. Table of Content: PART-A 1. Current Status of Fluorosis in World View 2. Current Status of fluorosis in India 3. Current Status of Fluorosis in West Bengal 4. Current Status of Fluorosis in Bankura. 4.1 Data Sheet of fluorosis endemicity 4.2 GIS Mapping of fluorosis endemic Block 5. Availability of fluoride-free water scheme by District administration 6. Programme Overview (NPPCF, Bnakura) 7.Performance and duties done by District Fluorosis Control Unit.Bankura.
  • 36. 1. Current Status of Fluorosis in World View Fluorosis is public health problem in 25 countries around the world.(DARK AREAS)
  • 37. 2. Current Status of fluorosis in India Jammu & Kashmir 7  No of affected Himachal Pradesh Arunachal District 204 (21 Punjab Delhi Pradesh States /UT) 82 Haryana 31 63 Rajastha Sikkim n Uttar Pradesh 22 Assam Nagaland  people affected, 62 Bihar 9 100.0 Gujarat 15 Manipur Tripura Mizoram million ( 6 million Madhya Pradesh children) 95 36 West Bengal Orissa 22 Maharashtra 31 56 70-100 % Districts affected  Causative factor, Andhra Pradesh 40-70 % Districts affected excess consumption Karnataka 70 67 10-40 % Districts affected of fluoride through <10% Districts affected drinking water Tamil Nadu Endemicity not known (>1.0ppm) and diet. 28 Kerala Andaman 21 Nicobar Source:A Treatise on Fluorosis by Dr. A.K. Susheela
  • 38. . Current Status of Fluorosis in West Bengal
  • 39. 4.0 Current Status of Fluorosis in Bankura.
  • 40. endemicity  Persons suffers from Fluorosis in India : 6 Million  (Dr. Raja Reddy , NIN , Hyderabad)  Persons suffers from Fluorosis in West Bengal: 2.20 Lakh  Persons Suffers from Fluorosis in Bankura: 90,742  Current Status of Fluorosis In Bankura District Affected Pop. Affected Pop. Affected Vill. Tot. Blocks Tot. Village in Bankura Habitation Habitation (Approx) (Approx) Affected. Tot. Pop. Tot. Pop. Affected Affected Block Pop. Pop. Tot. 22 31,92,695 15 20,21,341 90,742 3832 31,92,695 271 90,742 7778 1005 90,742
  • 41. 4.2 GIS Mapping of fluorosis endemic Block
  • 42.
  • 43. Bnakura) The Adviser (Nutrition) The District Consultant MH&FW.New Delhi.India (NPPCF.Bankura) I The National Consultant(NPPCF) The District Lab Tech (NPPCF) The DHS SH&FW. W.B. Field Workers The Add. (NPPCF) DHS(PH&CD) SH&FW. Swasthya Bhaban. Kol-91. W.B. The ADHS(MPHWS) & SPO (NPPCF)Swasthy a Bhaban. Kol-91. W.B. The CMOH and District Programme Officer. (NPPCF) The Dy. CMOH- II and District Nodal Officer(NPPCF)
  • 44. 7.Performance and duties done by District Fluorosis Control Unit.Bankura. • Successful implementation of this National Programme • Monitoring the programme by consulting all its The District Consultant Stake-Holders/Concern Persons under direct control of District Programme officers/District Nodal Officers. • Management and safe operating of Lab. Instrument. The District Lab Tech • Make ready report , Testing of Collected sample and as necessary he should also visit the endemic village for blood collection under supervision of his consultant and direct control od district officers. • Field Survey , sample collection and make ready report. • Make data-entry of patient line listing (As per state Field Investigators needed) • This National Programme will be successful if all district programme holders wants.
  • 45. Table of Content: PART - B 1. Fluorosis and fluoride 1.1 Fluoride 1.2 Pathophysiology of Fluorosis 2. Dental fluorosis 3. Skeletal Fluorosis 4. Non-Skeletal Manifestation 5. Laboratory Support 6. Prevention and Control Measure 7. Roll of PHED & DH&FWS. Bankura 5. Current Research on fluorosis
  • 46. Fluorosis and fluoride 1.1 Fluoride
  • 48. Ingestion of fluoride causes decrease in ionised calcium.  This hypocalcemia leads to changes in internal milieu of the body to maintain the calcium levels and leads to secondary hyperparathyroidism.  The increased parathyroid hormone causes increased activity of Osteoclasts in bone by activating membrane bound 3'5' Cyclic AMP.  This increased osteoclastic activity causes, increases in citric acid and lactic acid release from ruffled border of osteoclasts. This causes increase in hydrogen ion concentration, and hence lysis of lysosomes.  Release of lysosomal enzymes viz. acid protease, collagenase, hyaluronic acid in bone and other tissues of the body which catalyzes the reactions favoring the depolymerization of the glycoprotein of bone and of cartilage. This causes breakdown of hydroxyproline, which is responsible for stabilization of collagen triple helix.  As the protein polymer desegregates and dissolves, the mineral-binding capacity is also reduced and calcium is liberated, which helps in maintaining the serum calcium level. As a result the solubility of hydroxyappetite crystals also increases, causing its breakdown along with reduced laying down of collagen by reducing Hydroxylation of proline and lysine.  This event simultaneously led to the elevation of the serum mucoprotein or polysaccharide levels. The net result of degradation of ground substance in, bones and other calcified tissues like teeth leads to symptoms of Fluorosis like, delayed eruption of teeth, dental Fluorosis, clinical Fluorosis, premature aging etc
  • 49. Dental fluorosis Normal: The enamel surface is smooth, glossy and usually a pale creamy white in color. Mild: The white opacity of the enamel of the teeth is more extensive, but covers less than 50% of the tooth surface .
  • 50. Moderate:The enamel surface of the teeth shows marked wear and tear with brown stain and is frequently a disfiguring feature . Severe: The enamel surface is badly affected and hypoplasia is so marked that the general form of the tooth may be affected. There are pitted/worn out areas and widespread brownish discoloration with the teeth often having a corroded appearance.
  • 51. Types of skeletal fluorosis - I Genu valgum (KNOCK KNEES) Legs are bowed inwards in the standing position. The bowing usually occurs at or around the knee, and when standing with knees together, the feet are far apart. Genu Varum Legs are bowed outwards in the standing position. The bowing usually occurs at or around the knee. When standing with the feet together, the knees remains far apart.
  • 52. Types of skeletal fluorosis - II Kyphosis: – Forward bending of spine. Fixed and rigid thoracic cage as well as spinal cord compression occur Anterioposterior bowing of tibia
  • 53. Types of skeletal fluorosis - III Paraplegia: Spinal cord compression due to osteosclerosis with paraplegia as a result of endemic skeletal fluorosis
  • 54. NON SKELETAL MANIFESTATIONS  Tingling sensation in fingers and toes  Excessive thirst  Polydypsia and polyurea  Nervousness & Depression
  • 56. Table of Content: PART - C 1. Diagramatic view of Programme holder. NPPCF 2.Work Structure of National Programme for Prevention and Control of Fluorosis 2.1 District level planning of programme outlet. 2.2 Duties of Block Medical Officer of Health at District(BMOH) 2.3 Duties of Block Public Health Nurse(BPHN) 2.4 Duties of Supervisor at Gram Panchyaet Level. 2.5 Importance of ASHA at next phase of the programme.