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New Surgical Modalities in the Management
of the Colon and Rectal Cancer
Ted Voloyiannis, M.D., F.A.C.S., F.A.S.C.R.STed Voloyiannis, M.D., F.A.C.S., F.A.S.C.R.S
Clinical Assistant Professor in SurgeryClinical Assistant Professor in Surgery
University of Texas Houston, Health Sciences CenterUniversity of Texas Houston, Health Sciences Center
Houston, TexasHouston, Texas
Colon and Rectal SurgeryColon and Rectal Surgery
Memorial Hermann Medical GroupMemorial Hermann Medical Group
Chairman of SurgeryChairman of Surgery
Memorial Hermann Hospital SEMemorial Hermann Hospital SE
What is a Colorectal Surgeon ?
• Specialist for the Diagnosis and Treatment of
diseases involving the Colon, Rectum, and Anus.
(surgeon and proctologist)
• Board certified in General Surgery and Colorectal
Surgery
• American Society of Colon and Rectal Surgery
• www.fascrs.org
• www.mhmedicalgroup.org
Common Colon and Rectal Surgery Diseases and
Conditions
• Colon Cancer
• Rectal Cancer
• Anal Cancer
• Diverticulitis
• Colitis
– Crohn’s disease
– Ulcerative colitis
• Constipation
• Colonoscopy
Hemorrhoids
Fissures
Fistulas
Anal Warts
Rectal Bleeding
Incontinence
Every March in the USA is the
Colon and Rectal Cancer Awareness Month
Colon and Rectal Cancer:
Why Surgery?
• Early Colon and Rectal Cancer can be cured with surgery only. If
localized, 80-90% survival.
• Surgery as part of the multi treatment modality for advanced Colon and
Rectal Cancer.
• Palliative Surgery for Colon and Rectal Cancer.
When Do I Need Surgery?
• Colon or Rectal cancer
• A polyp with cancer within it
• A large polyp (greater than 2 cm)
• A polyp that cannot be removed safely with a
colonoscopy
Anatomy
Colon and Rectal Surgical Options
• Open Abdominal Surgery
• Combined approach (abdominal and perineal)
• Laparoscopic Abdominal via a Hand port or via a Single Port
• (Robotic) DaVinci Laparoscopic Assisted
• Anorectal -local surgery or via a Single Laparoscopic Port
Open or Laparoscopic Abdominal
Procedures
ž Right Colectomy
ž Extended Right Colectomy (Right
and Transverse)
ž Transverse Colectomy
ž Left Colectomy
ž Extended Left Colectomy
(Transverse and Descending)
ž Sigmoid Colectomy
Open or Laparoscopic Procedures
on the Rectum
• LAR – Low Anterior Resection
– With or without ileostomy
• APR- Abdomino-Perineal Resection
– Permanent colostomy
LAR APR
Type of anastomosis
• Anastomosis:
(Connecting two ends of bowel together)
– Hand sewn
– Stapled
– end to end
– side to side
– others
End to End Anastomosis
Side to side anastomosis
Side to side anastomosis
Side to side
anastomosis
Ostomies
• End Colostomy
• End Ileostomy
• Loop Ileostomy
Loop ileostomy
Innovative Techniques
• Laparoscopic Surgery via a Single Port
• Robotic – DaVinci Assisted Surgery
• Transanal Surgery via a Single Port
Laparoscopic Surgery
• Innovative method of operating and performing
surgery through very small incisions
• Also called “minimally invasive surgery”
• “Laparoscope” is a lens and video camera
• Laparoscope placed through “port” (small incision),
surgical instruments through 2 or 3 other “ports” to
allow surgeon to work inside the abdomen
21 slide 21
Laparoscopy v. “open” surgery
Laparoscopic SurgeryOpen Surgery
Laparoscopic Surgery
ž Smaller incisions
ž Less postop pain
ž Less hospital stay
ž Faster return of GI function
ž Faster return to full activity
ž May take longer
ž More expensive
ž Often more challenging technique
Robotic – “DaVinci” Assisted
Laparoscopic Surgery
• The same advantages as in laparoscopic surgery plus:
• Promises unsurpassed visualization, precision, dexterity and control for rectal /
pelvic surgery
• Equivalent outcomes to the Laparoscopic Surgery
Robotic Colon and Rectal Surgery
Robotic Surgical Platform
Robotic Surgery
Transanal Surgery for Mid or Low Early Rectal
Cancer
Anorectal Surgery
• Mostly outpatient or 23 hour
admission for observation
Role of genetic testing in Colon and Rectal Cancer
• 5-6% of colorectal cancers have a known genetic
mutation
• Hereditary Non Ponpolyposis Coli Syndrome,
Familial Adenomatous Polyposis and other
syndromes
• Young-age-of-onset colorectal cancer and other
organs
• Genetic counseling and testing useful when
prophylactic surgery is considered
Single Incision-Single Port Laparoscopic
Colon Surgery
Single Incision Surgery
• New tools and platforms
• Keep the procedure simple and safe
• Cost effective
SILS strategy
• Easily reproducible by surgeons with advanced laparoscopic
skills
• Eliminate use of single use items
• Use equipment that hospital already has available
• Eliminate additional training for OR personnel, surgical
assistant
Colon Resection
• Still <25% of colon surgery is performed laparoscopically across
the nation
• Majority of laparoscopic colon surgery is performed via the HALS
technique
• Most laparoscopic colon surgery is performed for right colectomy
• Multiport laparoscopy for colon surgery is performed still by the
minority of laparoscopists.
• Single incision port laparoscopy is “raising the bar” in colon and
rectal surgery
Less is More
• Technologic advances have allowed more surgical diseases to be
treated laparoscopically and have prompted us to refine our
techniques
• Smaller and fewer incisions and less trauma to benefit our
patients
• Natural orifice surgery has given birth to many areas of surgical
research
• New Surgical instruments
• Single incision surgery: a refinement of laparoscopic surgery,
introducing a multichannel port site with a 25-50mm total incision
New surgical instruments
• Wristed instruments
• Deflectable tip laparoscopes
• New endoscopic instruments for cutting, retrieving, and closing
devices
• New platforms for single incision surgery
SIL Devices
• SILS port (Covidien, Norwalk, CT, USA)
• GELPOINT access platform (Applied Medical, Rancho Santa
Margarita, CA, USA)
• GELPORT access platform (Applied Medical)
• TriPort system (Advanced Surgical Concepts, Wicklow, Ireland)
• Single Site Laparoscopy (SSL) Access Systems (Ethicon Endo-
Surgery Inc., Cincinnati, OH, USA)
• Quadport access system (Olympus AMerica, Center Valley, PA,
USA)
• Spider Surgical system (Transenterix, Durham, NC)
• R-Port System (Advanced Surgical Concepts)
• Uni-X Single Port Access Laparoscopic System (Pnavel Systems,
Morganville, New Jersey, USA)
Single incision ~ 2.5-3.5cm
Single incision for
laparoscopic colectomy!
SILS incision
Prostatectomy
Scar
Single incision scar 4 weeks
postop sigmoid colectomy
Single incision scar 4 weeks
postop sigmoid colectomy
Stretching the incision
Extraction of the specimen
Laparoscopic Single
Port “INCISION-
LESS”
Low Anterior
Resection/Loop
Ileostomy
SIL Colon and rectal surgery:
Applications
• Ileocecal resection
• Right colectomy
• Extended right colectomy
• Transverse colectomy
• Left colectomy
• Sigmoidectomy
• Low anterior resection w/wo ileostomy
• Restorative proctocolectomy with IPAA
• Colostomy
• Ileostomy
• Benign: polyp, diverticulitis, colo-vesical/vaginal fistula, IBD
• Colorectal malignancy
SILS is applicable to colorectal surgery
Advantages
• Improved cosmesis-shorter skin incision
• Less pain compared to multiport and hand assisted
laparoscopy
• Option for convertion to multiport or hand assisted laparoscopy
• No difference in conversion to open laparotomy
• Similar morbidity
• Similar operation time
• Similar oncologic outcomes for colorectal cancer surgery
• Safe compared to conventional laparoscopy
• Shorter hospital stay compared to conventional laparoscopy?
• Less total hospital cost compared to multiport laparoscopy and
laparotomy
SILS is applicable to colorectal surgery
Disadvantages
• Instrument conflict: Reduced excursion-cluster effect around
hands and camera
• Difficulty with exposure, ergonomics
• Cost for technology
• New and high learning curve that can complicate an already
challenging operation
• SILS is inherently a one-operating surgeon technique-potential
impact on resident education
Conclusion
• Single incision laparoscopic colectomy
is a safe and viable improvement on
conventional multiport laparoscopic
colectomy.
• Shorter hospital stay, less pain,
improved cosmesis, faster recovery,
similar oncologic safety.
• Future Randomized prospective trial
between MLPS and SILS.
• SILS ASCRS databank
India Ink Injection
The setupThe setup
The roomThe room
The ideal roomThe ideal room
Life in the real worldLife in the real world
The setupThe setup
The bedThe bed
Ports, Camera, Cables
Bariatric camera,
additional ports
Right angle for light source,
extra grasper
The InstrumentsThe Instruments
Vascular Ligation Bowel divisionVascular Ligation Bowel division
• Stapler
– Cost $250/$90 per
reload
– Safe for large
vessels
– Can divide bowel
– Easy and efficient
The InstrumentsThe Instruments
Vascular LigationVascular Ligation
• Energy devices
– High energy
coagulators,
– Vessels up to
7mm in size
– Infinite
applications
– 5mm and 10mm
units
– Easy to use
– Has difficulty with
calcified vessels
Single Port Laparoscopic
Colon Surgery in action!
Other applications of single port
in advanced laparoscopic colorectal surgery
• Splenic flexure mobilization, then LAR via Pfannenstiel incision.
• Ileostomy/colostomy reversal with ileorectal/colorectal anastomosis
• LAR with loop ileostomy for rectal CA/other (incision-less single
port!)
• Lap APR
• Lap LAR with Coloanal anastomosis
• Lap TPC with IPAA, loop ileostomy
• Lap Total colectomy
• Lap Right colectomy, extended Right.
• Transverse colectomy: laparoscopic resection with hand sewn
anastomosis?
• Takedown of colo-vesical/vaginal fistula
da Vinci Single Site
 Using da Vinci Si system with
8.5mm 3D HD endoscope
 Curved Instrument Cannulae
 5mm, non-wristed, semi-rigid
instruments
Instruments and accessories shown have not been cleared by the
FDA
(da Vinci Single Site prototype)
scope
Advanced Single Port or
NOTES
Flexible
Systems
Single Port  ~20mm diameter
 da Vinci-like capability
 Large range-of-motion
(multi-quadrant capability)
Robotic Systems – Single
Port Surgery
Instruments and Accessories shown are currently under product development
and have not been cleared by the Food and Drug Administration (FDA).
Summary
• Surgery in early Colon and Rectal Cancer can cure!
• Numerous surgical options and minimally invasive
techniques.
• Your surgeon will advocate the most suitable option.
• Genetic testing may be recommended.
29 slide 29
Which surgery is best for me?
• There are many factors involved in determining the best operative approach
• This question needs to be answered on an individual basis between the
patient and surgeon

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Rotary voloyiannis

  • 1. New Surgical Modalities in the Management of the Colon and Rectal Cancer Ted Voloyiannis, M.D., F.A.C.S., F.A.S.C.R.STed Voloyiannis, M.D., F.A.C.S., F.A.S.C.R.S Clinical Assistant Professor in SurgeryClinical Assistant Professor in Surgery University of Texas Houston, Health Sciences CenterUniversity of Texas Houston, Health Sciences Center Houston, TexasHouston, Texas Colon and Rectal SurgeryColon and Rectal Surgery Memorial Hermann Medical GroupMemorial Hermann Medical Group Chairman of SurgeryChairman of Surgery Memorial Hermann Hospital SEMemorial Hermann Hospital SE
  • 2. What is a Colorectal Surgeon ? • Specialist for the Diagnosis and Treatment of diseases involving the Colon, Rectum, and Anus. (surgeon and proctologist) • Board certified in General Surgery and Colorectal Surgery • American Society of Colon and Rectal Surgery • www.fascrs.org • www.mhmedicalgroup.org
  • 3. Common Colon and Rectal Surgery Diseases and Conditions • Colon Cancer • Rectal Cancer • Anal Cancer • Diverticulitis • Colitis – Crohn’s disease – Ulcerative colitis • Constipation • Colonoscopy Hemorrhoids Fissures Fistulas Anal Warts Rectal Bleeding Incontinence
  • 4. Every March in the USA is the Colon and Rectal Cancer Awareness Month
  • 5. Colon and Rectal Cancer: Why Surgery? • Early Colon and Rectal Cancer can be cured with surgery only. If localized, 80-90% survival. • Surgery as part of the multi treatment modality for advanced Colon and Rectal Cancer. • Palliative Surgery for Colon and Rectal Cancer.
  • 6. When Do I Need Surgery? • Colon or Rectal cancer • A polyp with cancer within it • A large polyp (greater than 2 cm) • A polyp that cannot be removed safely with a colonoscopy
  • 8. Colon and Rectal Surgical Options • Open Abdominal Surgery • Combined approach (abdominal and perineal) • Laparoscopic Abdominal via a Hand port or via a Single Port • (Robotic) DaVinci Laparoscopic Assisted • Anorectal -local surgery or via a Single Laparoscopic Port
  • 9. Open or Laparoscopic Abdominal Procedures ž Right Colectomy ž Extended Right Colectomy (Right and Transverse) ž Transverse Colectomy ž Left Colectomy ž Extended Left Colectomy (Transverse and Descending) ž Sigmoid Colectomy
  • 10. Open or Laparoscopic Procedures on the Rectum • LAR – Low Anterior Resection – With or without ileostomy • APR- Abdomino-Perineal Resection – Permanent colostomy
  • 12. Type of anastomosis • Anastomosis: (Connecting two ends of bowel together) – Hand sewn – Stapled – end to end – side to side – others
  • 13. End to End Anastomosis
  • 14. Side to side anastomosis
  • 15. Side to side anastomosis
  • 17. Ostomies • End Colostomy • End Ileostomy • Loop Ileostomy
  • 19. Innovative Techniques • Laparoscopic Surgery via a Single Port • Robotic – DaVinci Assisted Surgery • Transanal Surgery via a Single Port
  • 20. Laparoscopic Surgery • Innovative method of operating and performing surgery through very small incisions • Also called “minimally invasive surgery” • “Laparoscope” is a lens and video camera • Laparoscope placed through “port” (small incision), surgical instruments through 2 or 3 other “ports” to allow surgeon to work inside the abdomen
  • 21. 21 slide 21 Laparoscopy v. “open” surgery Laparoscopic SurgeryOpen Surgery
  • 22. Laparoscopic Surgery ž Smaller incisions ž Less postop pain ž Less hospital stay ž Faster return of GI function ž Faster return to full activity ž May take longer ž More expensive ž Often more challenging technique
  • 23. Robotic – “DaVinci” Assisted Laparoscopic Surgery • The same advantages as in laparoscopic surgery plus: • Promises unsurpassed visualization, precision, dexterity and control for rectal / pelvic surgery • Equivalent outcomes to the Laparoscopic Surgery
  • 24. Robotic Colon and Rectal Surgery
  • 27. Transanal Surgery for Mid or Low Early Rectal Cancer
  • 28. Anorectal Surgery • Mostly outpatient or 23 hour admission for observation
  • 29. Role of genetic testing in Colon and Rectal Cancer • 5-6% of colorectal cancers have a known genetic mutation • Hereditary Non Ponpolyposis Coli Syndrome, Familial Adenomatous Polyposis and other syndromes • Young-age-of-onset colorectal cancer and other organs • Genetic counseling and testing useful when prophylactic surgery is considered
  • 30. Single Incision-Single Port Laparoscopic Colon Surgery
  • 31. Single Incision Surgery • New tools and platforms • Keep the procedure simple and safe • Cost effective
  • 32. SILS strategy • Easily reproducible by surgeons with advanced laparoscopic skills • Eliminate use of single use items • Use equipment that hospital already has available • Eliminate additional training for OR personnel, surgical assistant
  • 33. Colon Resection • Still <25% of colon surgery is performed laparoscopically across the nation • Majority of laparoscopic colon surgery is performed via the HALS technique • Most laparoscopic colon surgery is performed for right colectomy • Multiport laparoscopy for colon surgery is performed still by the minority of laparoscopists. • Single incision port laparoscopy is “raising the bar” in colon and rectal surgery
  • 34. Less is More • Technologic advances have allowed more surgical diseases to be treated laparoscopically and have prompted us to refine our techniques • Smaller and fewer incisions and less trauma to benefit our patients • Natural orifice surgery has given birth to many areas of surgical research • New Surgical instruments • Single incision surgery: a refinement of laparoscopic surgery, introducing a multichannel port site with a 25-50mm total incision
  • 35. New surgical instruments • Wristed instruments • Deflectable tip laparoscopes • New endoscopic instruments for cutting, retrieving, and closing devices • New platforms for single incision surgery
  • 36. SIL Devices • SILS port (Covidien, Norwalk, CT, USA) • GELPOINT access platform (Applied Medical, Rancho Santa Margarita, CA, USA) • GELPORT access platform (Applied Medical) • TriPort system (Advanced Surgical Concepts, Wicklow, Ireland) • Single Site Laparoscopy (SSL) Access Systems (Ethicon Endo- Surgery Inc., Cincinnati, OH, USA) • Quadport access system (Olympus AMerica, Center Valley, PA, USA) • Spider Surgical system (Transenterix, Durham, NC) • R-Port System (Advanced Surgical Concepts) • Uni-X Single Port Access Laparoscopic System (Pnavel Systems, Morganville, New Jersey, USA)
  • 37. Single incision ~ 2.5-3.5cm
  • 38. Single incision for laparoscopic colectomy! SILS incision Prostatectomy Scar
  • 39. Single incision scar 4 weeks postop sigmoid colectomy
  • 40. Single incision scar 4 weeks postop sigmoid colectomy
  • 42. Extraction of the specimen
  • 43. Laparoscopic Single Port “INCISION- LESS” Low Anterior Resection/Loop Ileostomy
  • 44. SIL Colon and rectal surgery: Applications • Ileocecal resection • Right colectomy • Extended right colectomy • Transverse colectomy • Left colectomy • Sigmoidectomy • Low anterior resection w/wo ileostomy • Restorative proctocolectomy with IPAA • Colostomy • Ileostomy • Benign: polyp, diverticulitis, colo-vesical/vaginal fistula, IBD • Colorectal malignancy
  • 45. SILS is applicable to colorectal surgery Advantages • Improved cosmesis-shorter skin incision • Less pain compared to multiport and hand assisted laparoscopy • Option for convertion to multiport or hand assisted laparoscopy • No difference in conversion to open laparotomy • Similar morbidity • Similar operation time • Similar oncologic outcomes for colorectal cancer surgery • Safe compared to conventional laparoscopy • Shorter hospital stay compared to conventional laparoscopy? • Less total hospital cost compared to multiport laparoscopy and laparotomy
  • 46. SILS is applicable to colorectal surgery Disadvantages • Instrument conflict: Reduced excursion-cluster effect around hands and camera • Difficulty with exposure, ergonomics • Cost for technology • New and high learning curve that can complicate an already challenging operation • SILS is inherently a one-operating surgeon technique-potential impact on resident education
  • 47. Conclusion • Single incision laparoscopic colectomy is a safe and viable improvement on conventional multiport laparoscopic colectomy. • Shorter hospital stay, less pain, improved cosmesis, faster recovery, similar oncologic safety. • Future Randomized prospective trial between MLPS and SILS. • SILS ASCRS databank
  • 49. The setupThe setup The roomThe room The ideal roomThe ideal room Life in the real worldLife in the real world
  • 53. Right angle for light source, extra grasper
  • 54. The InstrumentsThe Instruments Vascular Ligation Bowel divisionVascular Ligation Bowel division • Stapler – Cost $250/$90 per reload – Safe for large vessels – Can divide bowel – Easy and efficient
  • 55. The InstrumentsThe Instruments Vascular LigationVascular Ligation • Energy devices – High energy coagulators, – Vessels up to 7mm in size – Infinite applications – 5mm and 10mm units – Easy to use – Has difficulty with calcified vessels
  • 56. Single Port Laparoscopic Colon Surgery in action!
  • 57. Other applications of single port in advanced laparoscopic colorectal surgery • Splenic flexure mobilization, then LAR via Pfannenstiel incision. • Ileostomy/colostomy reversal with ileorectal/colorectal anastomosis • LAR with loop ileostomy for rectal CA/other (incision-less single port!) • Lap APR • Lap LAR with Coloanal anastomosis • Lap TPC with IPAA, loop ileostomy • Lap Total colectomy • Lap Right colectomy, extended Right. • Transverse colectomy: laparoscopic resection with hand sewn anastomosis? • Takedown of colo-vesical/vaginal fistula
  • 58. da Vinci Single Site  Using da Vinci Si system with 8.5mm 3D HD endoscope  Curved Instrument Cannulae  5mm, non-wristed, semi-rigid instruments Instruments and accessories shown have not been cleared by the FDA (da Vinci Single Site prototype) scope
  • 59. Advanced Single Port or NOTES Flexible Systems Single Port  ~20mm diameter  da Vinci-like capability  Large range-of-motion (multi-quadrant capability)
  • 60. Robotic Systems – Single Port Surgery Instruments and Accessories shown are currently under product development and have not been cleared by the Food and Drug Administration (FDA).
  • 61. Summary • Surgery in early Colon and Rectal Cancer can cure! • Numerous surgical options and minimally invasive techniques. • Your surgeon will advocate the most suitable option. • Genetic testing may be recommended.
  • 62. 29 slide 29 Which surgery is best for me? • There are many factors involved in determining the best operative approach • This question needs to be answered on an individual basis between the patient and surgeon

Editor's Notes

  1. Intuitive Surgical is currently working on a single port solution that works on the da Vinci Si platform. These instruments are currently in development and have not been cleared by the FDA. As you can see, there are two curved cannulae and an endoscope that all cross at the same remote center enable access through a single incision (remote center signified by red circle). This allows for triangulation at the target anatomy while allowing the instrument arms sufficient range of motion without collisions (range of motion signified by yellow arrows). The instruments being developed have semi-rigid shafts that allow them to be inserted through the curved cannulae to reach the surgical site and are controlled by the surgeon via the surgeon console. The da Vinci Si system allows the masters to be swapped to accommodate the crossing of the cannulae. In other words, in the surgeon console viewer right appears right and left appears left, even though the instruments are crossed. This brings intuitiveness as well as the many benefits of da Vinci Surgery to single site surgery.
  2. Single Port: The premise of advanced single port surgery is to take single port surgery to the next level from the da Vinci Single Site platform. This is a single port trocar with a “chip on a stick” vision system….in other words, the camera and light source is flexible instead of rigid and the head can be manipulated and controlled…essentially an endoscope with a snake like head. In order to maneuver these single port instruments, you need a whole new patient cart that can manipulate and control them, this is the picture in the lower left corner of the slide. With this advanced architecture, single port surgery could be done transumbilical, transvaginal, transoral, or even transanal. Flexible Systems: With a completely flexible system, such as the snake like rendering you see in the upper right depiction, a surgeon could run this system through the intestines to target specific anatomy. This is the premise of NOTES surgery (Natural Orifice Transluminal Endoscopic Surgery) that we may see in the future. Because the da Vinci system is intelligent and knows where it’s instrument tips are in 3D space, if we can determine where the entire snake body is in 3D space, then we can accurately direct this snake like structure through the digestive system with no need to enter a patient through an exterior incision.
  3. Here is an initial prototype of a single port surgial system with completely wristed instrumentation. As you can see, there are wrists and even elbows in this architecture. Likewise, in the upper right of the screen you can see the endoscope that also came through that single port. As we continue to advance MIS robotic surgery, the opportunities and advancements like we see in this video offer new challenges….but most importantly, new opportunities to increase the effectiveness of surgery while reducing the invasiveness.