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Case Presentation
Dr. Md. Seebat Masrur
D-card Student
Cardiology Department
SZMCH, Bogra
Demographic Details
• Name: Mamun
• Age: 16 years
• Sex: Male
• Religion: Islam
• Occupation: Student
• Marital status: Un-married
• Address: Vatakanda, Sirajgonj
• Date of admission: 18.07.2022
• Date of examination:
18.07.2022
Chief Complaints
1) Joint pain involving large joints left hip, right
knee and both ankles.
2) Swelling of joints for same duration
History of Present Illness
According to the statement of the patient, he
was reasonably well 12 days back. Then he
developed joint pain which was severe in
intensity involving Left hip, right knee and
both ankles. Initially involved left hip then
sequentially migrating to right knee and both
ankle joints. The joints were swollen, red , hot
and very painful even with slight movement.
The smaller joints were not involved. There
was no morning stiffness.
History of Present Illness (cont...)
There is no history of abnormal or involuntary
movement or skin changes. He denied any
fever, sore throat, breathlessness, palpitation,
chest pain, low back pain, malaise, fatigue,
weakness during this disease period. No
history of diarrhoea, mouth ulcer, uveitis or
any urinary complaints.
Past Medical History
No Significant past medical history.
Family History
His parents are alive. He has an elder sister. All
his family members are healthy.
Socioeconomic History
He belongs to a lower middle class family.He
lives in a tin shed house which has two rooms.
He shares his room with his sibling. Drinks
tube-well water.
Drug History
He took some painkiller during disease
period the name could not be mentioned
which partially relived his pain.
Immunization History
He was immunized according to EPI schedule.
Personal History
He is non smoker, non alcoholic. No H/O
intravenous drug abuse.
PHYSICAL EXAMINATION
General Examination
• Appearance: Ill-looking
• Co-operation: Co-operative
• Decubitus: On choice
• Build: Average
• Nutrition: Below average
• Intelligence: Normal
• Anemia: Absent
• Jaundice: Absent
• Cyanosis: Absent
General Examination (cont...)
• Oedema: Absent
• Dehydration: Absent
• Clubbing: Absent
• Koilonychia: Absent
• Leukonychia: Absent
• Neck vein: Not engorged
• Thyroid gland: Not enlarged
• Lymph nodes: Not palpable
• Skin condition: Normal
• Hair distribution: Normal
General Examination (cont...)
• Weight: 47 kg
• Pulse: 92/min
• Blood Pressure: 100/60mmHg
• Temperature: 98 F
• Respiratory rate: 16/min
SYSTEMIC EXAMINATION
Cardiovascular System
• Pulse: 92 B/mins
• BP: 100/60 mm hg
• JVP: Not Raised
• Precordium examination:
Inspection:
Shape: Normal
No visible cardiac impulse
No scar marks, no deformity.
Cardiovascular …
Palpation:
Apex beat: Left 5th ICS just lateral to mid
clavicular line.
Thrills: Absent
Left Parasternal heave: Absent
Epigastric Pulsation: Absent
Cardiovascular…
Ausculatation:
First and 2nd heart Sound: Normal
No murmur present
No Added sound
Locomotor examination
Inspection
Mildly swollen
Normal Skin condition
Palpation
Local temperature: Mildly
raised
Tenderness: Present
Fluctuation test: Negative
Movement: Restricted due to
pain
Other systemic examinations
revealed no abnormality.
Salient Feature
Mamun 16-year-old, student, normotensive,
nondiabetic, nonsmoker, hailing from
vatakanda, Sirajgonj he developed migrating,
inflammatory large joints severe pain which
sequentially involved the Left hip, right knee,
both ankles. He felt pain even with mild
movement. The small joints are not involved
and there was no morning stiffness.
Salient Feature…
There is no history of abnormal movement or
skin changes. The patient denied any prior fever,
sore throat, malaise fatigue. He denied any
history of diarrhea, sexual exposure, low back
pain, mouth ulcer, uveitis or any urinary
complaint. He used to take some painkillers
which partially relieved his symptoms. There is
no family history of such illness.
Salient Feature…
He belongs to a lower middle-class family,
Shares his room with his sibling. He was duly
immunized. No history of prior drug use.
CLINICAL DIAGNOSIS
?
Acute Rheumatic
fever
Differential Diagnosis
Infective arthritis (viral or bacterial).
Juvenile Idiopathic arthritis.
Seronegative arthritis.
Acute Gouty Arthritis
Rheumatoid Arthritis
INVESTIGATION PROFILE
Name of investigations Findings
CBC with ESR • Hb%: 11.30 gm/dl
• WBC: 14670/cumm
• Neutrophil: 76%
• Platelet: 598000/cumm
• ESR: 121 mm in 1st hour
CRP •139mg/L
ASO Titre • 400 IU/ml
12 Lead ECG
• This is a 12-lead ECG with Rhythm strip showing rate 96
beats/min, rhythm is regular, PR interval is normal, T wave
inversion from v1-v4.
Investigation Profile (cont...)
Name of investigations Findings
CXR P/A View Normal findings
Throat Swap Culture Pending
Ra factor Negative
Uric Acid 4.30 mg/dl
Echocardiography
• Normal 2D & M-mode
echocardiography with Good LV
systolic function with EF 75%.
FINAL DIAGNOSIS
Acute Rheumatic Fever
Points In Favour
• Migrating, inflammatory arthritis involving the
large joints without any deformity.
• Leukocytosis
• Raised ASO titre.
• High ESR & CRP
Management
• Bed Rest until symptoms subsides.
• Oral Phenoxymethylpenicillin 250 mg 6 hrly
for 10 days
• Analgesic- Aspirin 60 to 100 mg/kg per day in
divided dosages.(not more than 8 gm/day)
• Prednisolone 1-2 mg/kg body weight for 2
weeks then gradually tapered over 2 weeks,
Monitoring of patient
• ESR
• CRP
• Serial ECHO
• ASO Titre is not required
Treatment on Discharge
• Tab Phenoxymethyl penicillin 250
mg…..1+0+1…….5 years
• Tab Aspirin 75 mg
• Tab Omeprazole 20mg….1+0+1(B/M)…….2
months
• Tab Prednisone 20 mg….2+0+0………7 days
then tab prednisolone 1+0+0……….7 days then
tab prednisone 20mg….1/2+0+0…….7 days
THANK YOU

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Rheumatic fever1.pptx

  • 1. Case Presentation Dr. Md. Seebat Masrur D-card Student Cardiology Department SZMCH, Bogra
  • 2. Demographic Details • Name: Mamun • Age: 16 years • Sex: Male • Religion: Islam • Occupation: Student • Marital status: Un-married • Address: Vatakanda, Sirajgonj • Date of admission: 18.07.2022 • Date of examination: 18.07.2022
  • 3. Chief Complaints 1) Joint pain involving large joints left hip, right knee and both ankles. 2) Swelling of joints for same duration
  • 4. History of Present Illness According to the statement of the patient, he was reasonably well 12 days back. Then he developed joint pain which was severe in intensity involving Left hip, right knee and both ankles. Initially involved left hip then sequentially migrating to right knee and both ankle joints. The joints were swollen, red , hot and very painful even with slight movement. The smaller joints were not involved. There was no morning stiffness.
  • 5. History of Present Illness (cont...) There is no history of abnormal or involuntary movement or skin changes. He denied any fever, sore throat, breathlessness, palpitation, chest pain, low back pain, malaise, fatigue, weakness during this disease period. No history of diarrhoea, mouth ulcer, uveitis or any urinary complaints.
  • 6. Past Medical History No Significant past medical history.
  • 7. Family History His parents are alive. He has an elder sister. All his family members are healthy.
  • 8. Socioeconomic History He belongs to a lower middle class family.He lives in a tin shed house which has two rooms. He shares his room with his sibling. Drinks tube-well water.
  • 9. Drug History He took some painkiller during disease period the name could not be mentioned which partially relived his pain.
  • 10. Immunization History He was immunized according to EPI schedule.
  • 11. Personal History He is non smoker, non alcoholic. No H/O intravenous drug abuse.
  • 12. PHYSICAL EXAMINATION General Examination • Appearance: Ill-looking • Co-operation: Co-operative • Decubitus: On choice • Build: Average • Nutrition: Below average • Intelligence: Normal • Anemia: Absent • Jaundice: Absent • Cyanosis: Absent
  • 13. General Examination (cont...) • Oedema: Absent • Dehydration: Absent • Clubbing: Absent • Koilonychia: Absent • Leukonychia: Absent • Neck vein: Not engorged • Thyroid gland: Not enlarged • Lymph nodes: Not palpable • Skin condition: Normal • Hair distribution: Normal
  • 14. General Examination (cont...) • Weight: 47 kg • Pulse: 92/min • Blood Pressure: 100/60mmHg • Temperature: 98 F • Respiratory rate: 16/min
  • 16. Cardiovascular System • Pulse: 92 B/mins • BP: 100/60 mm hg • JVP: Not Raised • Precordium examination: Inspection: Shape: Normal No visible cardiac impulse No scar marks, no deformity.
  • 17. Cardiovascular … Palpation: Apex beat: Left 5th ICS just lateral to mid clavicular line. Thrills: Absent Left Parasternal heave: Absent Epigastric Pulsation: Absent
  • 18. Cardiovascular… Ausculatation: First and 2nd heart Sound: Normal No murmur present No Added sound
  • 19. Locomotor examination Inspection Mildly swollen Normal Skin condition Palpation Local temperature: Mildly raised Tenderness: Present Fluctuation test: Negative Movement: Restricted due to pain
  • 21. Salient Feature Mamun 16-year-old, student, normotensive, nondiabetic, nonsmoker, hailing from vatakanda, Sirajgonj he developed migrating, inflammatory large joints severe pain which sequentially involved the Left hip, right knee, both ankles. He felt pain even with mild movement. The small joints are not involved and there was no morning stiffness.
  • 22. Salient Feature… There is no history of abnormal movement or skin changes. The patient denied any prior fever, sore throat, malaise fatigue. He denied any history of diarrhea, sexual exposure, low back pain, mouth ulcer, uveitis or any urinary complaint. He used to take some painkillers which partially relieved his symptoms. There is no family history of such illness.
  • 23. Salient Feature… He belongs to a lower middle-class family, Shares his room with his sibling. He was duly immunized. No history of prior drug use.
  • 26. Differential Diagnosis Infective arthritis (viral or bacterial). Juvenile Idiopathic arthritis. Seronegative arthritis. Acute Gouty Arthritis Rheumatoid Arthritis
  • 27. INVESTIGATION PROFILE Name of investigations Findings CBC with ESR • Hb%: 11.30 gm/dl • WBC: 14670/cumm • Neutrophil: 76% • Platelet: 598000/cumm • ESR: 121 mm in 1st hour CRP •139mg/L ASO Titre • 400 IU/ml
  • 28. 12 Lead ECG • This is a 12-lead ECG with Rhythm strip showing rate 96 beats/min, rhythm is regular, PR interval is normal, T wave inversion from v1-v4.
  • 29. Investigation Profile (cont...) Name of investigations Findings CXR P/A View Normal findings Throat Swap Culture Pending Ra factor Negative Uric Acid 4.30 mg/dl
  • 30. Echocardiography • Normal 2D & M-mode echocardiography with Good LV systolic function with EF 75%.
  • 32. Points In Favour • Migrating, inflammatory arthritis involving the large joints without any deformity. • Leukocytosis • Raised ASO titre. • High ESR & CRP
  • 33. Management • Bed Rest until symptoms subsides. • Oral Phenoxymethylpenicillin 250 mg 6 hrly for 10 days • Analgesic- Aspirin 60 to 100 mg/kg per day in divided dosages.(not more than 8 gm/day) • Prednisolone 1-2 mg/kg body weight for 2 weeks then gradually tapered over 2 weeks,
  • 34. Monitoring of patient • ESR • CRP • Serial ECHO • ASO Titre is not required
  • 35. Treatment on Discharge • Tab Phenoxymethyl penicillin 250 mg…..1+0+1…….5 years • Tab Aspirin 75 mg • Tab Omeprazole 20mg….1+0+1(B/M)…….2 months • Tab Prednisone 20 mg….2+0+0………7 days then tab prednisolone 1+0+0……….7 days then tab prednisone 20mg….1/2+0+0…….7 days