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Correlative light and electron microscopy (CLEM) is the combination of fluorescence microscopy (FM) and high-resolution electron microscopy (EM). Diabetes Type 1, one of the two widely spread forms, is an autoimmune decease, which is caused by the destruction of insulin-producing beta cells in the pancreas. A better understanding of this form of Diabetes could be obtained from a rigorous study of the islets of Langerhans. This can be done by imaging them with an electron microscope (EM) and fluorescence microscope combined in one. This technique called correlative microscopy is commonly applied in life sciences.
The SECOM platform is an integrated CLEM that is produced and designed by Delmic. Delmic offers a unique solution for simultaneous correlative light and electron microscopy.
In this presentation, you can learn how integrated CLEM can be performed to study and better understand type 1 diabetes.
For questions about correlative microscopy and the SECOM, please leave a comment below or visit www.delmic.com and send us a message. We will respond to your questions as soon as possible!