En los pacientes de bajo riesgo se evalua ambulatorio vs internado, oral vs endovenoso. Se tratan de poblaciones heterogeneas con pocas complicaciones
Inpatient versus outpatient—Forest plot of treatment failure. Squares to the left of the vertical line indicate a decreased risk of developing treatment failure in patients receiving inpatient management. Horizontal lines through the squares represent 95% confidence intervals (CIs). The diamonds represent the overall risk ratio (RR) from the meta-analyses and the corresponding 95% CIs.
Intravenous versus oral treatment in ambulatory care—Forest plot of treatment failure. Squares to the left of the vertical line indicate a decreased risk in developing treatment failure in patients receiving intravenous antibiotics. Horizontal lines through the squares represent 95% CIs. The diamonds represent the overall risk ratio (RR) from the meta-analyses and the corresponding 95% confidence intervals. p.o. = oral.
Scoring index for identification of low-risk febrile neutropenic patients at time of presentation with fever.
Zinner SH . Changing epidemiology of infections in patients with neutropenia and cancer: emphasis on gram-positive and resistant bacteria. Clin Infect Dis 1999;29:490-4. Abstract/FREE Full Text ↵ Wisplinghoff H, Seifert H,Wenzel RP, et al . Current trends in the epidemiology of nosocomial bloodstream infections in patients with hematological malignancies and solid neoplasms in hospitals in the United States. Clin Infect Dis 2003;36:1103-10. Abstract/FREE Full Text
Initial management of fever and neutropenia. *Limited data to support recommendation. ANC, absolute neutrophil count; CT, computed tomography; MRI, magnetic resonance imaging.
Reassess after 2-4 days of empirical antibiotic therapy. ANC, absolute neutrophil count; CT, computed tomography; IV, intravenous; MRI, magnetic resonance imaging.
High-risk patient with fever after 4 days of empirical antibiotics. C. difficile, Clostridium difficile; IV, intravenous.
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