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Getting Closer to Customers:
Mobility Revolution in Pharmaceuticals
   Executive Summary                                       focus on patients over the years. The situation
                                                           is accentuated by the specific nature of the
   The mobile revolution has irrevocably changed the
                                                           pharmaceutical industry. Consider the following:
   way the world communicates. The initial contours
   of this change were felt in the social dimension,
   where communication barriers between individu-
                                                           •   A huge amount of money is spent on inventing
                                                               very few products, with perhaps one major
   als were eased. Over time, fueled by fertile minds,         drug launched every couple of years or so.
   the contours extended to the business dimension,
   where greater effectiveness was achieved                •   Consumers are not the decision-makers, and
   by establishing a personal connection with                  it’s very hard to directly reach them.
   customers, which hitherto was almost impossible         •   Reaching the influencers is increasingly
   in some industry segments, such as pharmaceu-               difficult, with more oversight by regulators.
   ticals.                                                     Payers are increasingly exerting decisive
                                                               influence over the success of the product.
   This paper looks at how the mobile revolution
   is transforming the pharmaceutical industry by          •   Ethical concerns surround how drugs are
   enabling a consumer-to-industry connection. It              tested in clinical and pre-clinical stages.
   proceeds to give a glimpse of the transforma-           •   Over-the-shoulder regulatory supervision
   tion by discussing three real-life examples and             exists in almost all activities.
   concludes with a discussion on future trends and
   challenges.                                             Pharmaceutical products reach consumers
                                                           mostly through their prescribing physician. The
   Industry Challenges                                     commercial focus has been predominantly on
   Pharmaceuticals companies are in the business           figuring out how to encourage physicians to
   of offering products that save lives and enhance        prescribe more of their products. It is estimated
   quality of life. Undeniably, the innovations of phar-   that $19 billion is spent by pharmaceuticals
   maceuticals have helped millions of people lead         companies on drug promotion in the U.S., alone.1
   dignified lives. Our healthy future is predicated on
                                                           Several key applications have been built by all
   our ability to access required medicinal products.
                                                           pharmaceuticals companies to try to understand
   With increasing preference for generics over
                                                           physician prescribing patterns, ways to ethi-
   branded drugs, the pharmaceutical industry is
                                                           cally influence prescribers, types of marketing
   facing severe revenue pressure. This, coupled
                                                           campaigns targeting select prescribers in select
   with other industry forces like managing payers
                                                           territories, etc. Similarly, applications that
   and regulatory authorities, has diluted the
                                                           monitor drug safety, help with drug discovery




   cognizant 20-20 insights | november 2011
and track interactions with regulators have also         engage with physicians. Manhattan Research
been built. However, it would be surprising to find      estimates that about 81% of physicians will
any application that directly talks about consum-        own smartphone devices by 2012.6 This mobile
ers and their opinion of the product, partly due         revolution has come as a silver lining, offering
to the peculiar nature of the industry. Building         new ways to engage with physicians. New mobility
a better understanding of customer sentiments            applications target not only the traditional sales
and consumer experiences with any pharmaceu-             force but also the patient community by offering
tical product has been made very difficult by the        wellness-based, informative applications.
lack of direct customer access. The onset of social
media, coupled with emerging channels, has               Emerging channels such as Web portals and
introduced a welcome change in this direction.           mobile devices enable consumers with the latest
                                                         information about pharmaceutical products.
Social media and emerging channels for interac-          Social networks empower consumers by forming
tion have opened pathways for better connec-             a community. Offering opinions and hearing
tions to both patients and physicians. According         advice from more experienced consumers is now
to recent estimates, Facebook has more than              a reality. This can improve or mar the chances of
500 million subscribers, and Twitter recently sur-       success for pharmaceutical products. With every
passed 190 million users (who tweet 65 million           passing day, the increasing consumer influence
times per day).2 Mining from social networking           on pharmaceuticals is felt.
sites, one can get a wealth of information, from
recruiting for clinical trials, to figuring out active   In his classic work on Web 2.0,7 Tim O’Reilly
physicians and their preferences. Pharmaceuti-           observes with great foresight that harnessing
cal companies are conscious of the emergence             collective intelligence is about “users themselves
of new power centers and the gravity shifts. For         deciding what is important for them rather than
more effective connections with their consumer           a few people in a back room deciding what is
community, these companies are supporting                important for users.” Of course, the context of
brand Web sites, which provide a host of informa-        this remark was that of Web page rankings, but
tion about the product. One of the most success-         we can see the extension of this thought mani-
ful instances is Novartis’s Glivec Web sites,3 which     festing itself in the form of “harnessing collecting
provide a lot of useful consumer information.            intelligence” elsewhere. In the context of the
                                                         pharmaceutical industry, we see the following
The Mobile Revolution:                                   uses for collective intelligence:
The Pharma Impact
Tectonic shifts in technology innovations open up
                                                         •   Payer community: Direct evidence from
                                                             consumers on their perception of the efficacy
innovative avenues to capitalize on these changes            of pharmaceutical products.
and improve human life. Ubiquitous, affordable,
easy-to-use mobile devices are probably the most         •   Pharmaceutical: The ability to hear the
significant technology innovation to occur in the            customer voice directly and gain valuable
past few years. “Hyper-connection” is the order of           insights from it.
the day, and the trend is irreversible. Unimagined       •   Consumers: The ability to influence the future
possibilities are now on the verge of realization,           of pharmaceutical products.
due to the wide prevalence of mobile devices and
formation of virtual communities. With interest-         The mobile revolution has given power to the
ing research happening in the areas of location-         average Joe to generate opinions and increase
aware 4 and context-aware5 mobile applications,          his social networking possibilities. This increase in
pharmaceuticals companies will be able to touch          social networking traffic requires elastic storage
the lives of their consumers in novel and fruitful       and processing capabilities. Cloud solutions
ways.                                                    provide the right kind of infrastructure for intel-
                                                         ligence generation. One can see the link between
Access to physicians for pharmaceuticals sales           mobile applications, social networks and cloud
executives is increasingly becoming a challenge.         solutions. There are interesting applications
Physicians are shifting to more convenient               that pharmaceuticals can create for monitoring
channels for interaction such as the Web, which          health conditions via an implanted device and a
offers the flexibility of being available anytime        physician’s mobile device, which can change the
with the most recently updated information.              contour of care beyond the known boundaries of
Pharmaceuticals are forced to find new ways to           today.



                         cognizant 20-20 insights        2
Mobile App for Consumer-Physician-Payer Connection


                                                   Consumer



           This app enables a channel of                                 Higher customer satisfaction will positively
           interaction, aimed at customer care.                          influence the payer, resulting in more
                                                                         business for pharmaceuticals.



                                       Physician                    Payer




Figure 1



We studied the popular applications developed                 advances, pharmaceuticals are experimenting
by pharmaceuticals that are targeted toward                   with novel mobile applications that can notify the
consumers. In parallel, we also looked at the inter-          physician about the consumer’s health instanta-
esting mobile applications available in the public            neously. This application enables the physician
domain pertaining to healthcare. With these,                  to work even when he is not in the office. Such a
we identified the broad themes and picked out                 capability transcends the constraints of time and
mobility applications in which these themes were              space, demonstrating customer care practically
well-expressed. We will describe three such appli-            anytime, anywhere. Figure 1 illustrates how the
cations that are illustrative of the technology and           application fits in the pharmaceutical-consumer-
domain trends.                                                physician chain.

Three Real-Life Examples                                      The simplified flow of this application is depicted
Pharmaceuticals are motivated by the desire to                in Figure 2.
improve consumer health and well-being. The
mobile revolution has enabled computing power                 Automatic Transmission of Alerts
in mobile devices, and pharmaceuticals are taking
                                                              from Consumers to Care Providers
advantage of that to improve consumer health.
The examples below are linked by this common
theme: how to use the mobile revolution to
improve consumer satisfaction and enable higher
quality of life. We will see how each of these                           Implanted           Transmissions
manifests this theme in innovative ways.                                  Device               Database

Remote Patient Monitoring
The market for medical devices is growing briskly.                                                            Alerts
Market size for medical devices in the U.S. was                                                              Generator
about $94.9 billion in 2010.8 Medical devices are
capable of automatically transmitting the health
conditions of the consumer to the physician,                             Mobile                 Push
                                                                          Apps               Notification
who uses this information to assess the patient’s                                              Server
health. Currently, this is mostly being done by
logging on to a Web site and viewing the transmis-
sions or using hard copies, both of which generally
introduce a time lag. Exploiting the technological            Figure 2




                            cognizant 20-20 insights          3
The Salubris Ecosystem


                          REST
           End Users      Calls
           iPhone/iPad                    Web Services


                                                                       Rx (prescription details)                                   Care Provider
            Android
                                    Web Application
                                                                       Logs into wellness application
                                                                       and provisions device to patients
           Blackberry
                                  Multitenant Provisioning

                                    ETL     Analytic         Insight
                                           Warehouse

                                                                                      1. Correlation between exercise and mood level
                                                                                      2. Analytics between blood glucose vs.stress
                                                                                      3. .....
                                  EMR
                                             Google/MS HV
                                                                                                 Health Info
                                                                                                  Exchange



Figure 3


Salubris: A Wellness Framework                                     Such a correlation will help in establishing
Wellness — whose responsibility is it? The consum-                 evidence of whether the drug worked as expected.
ers? Pharmaceuticals? Physicians? Ultimately,                      It is of invaluable help for the payer community,
wellness is the consumer’s responsibility, and the
entire ecosystem can and should help the con-
                                                                   Correlation of Vitals to Symptoms
sumer achieve it. The seed idea of the Salubris
                                                                                                         Blood Glucose Tracker Graph
                                                                           Blood Glucose Value




platform is using mobility technology to empower
patients to take charge of their wellness and, in                                                 40
the process, generate real-world evidence to help                                                 30                                                        < 30
both pharmaceuticals and the payer community.                                                     20
                                                                                                  10
                                                                                                         JFM      AM J   JAS                     OND
Salubris provides the ability to set medication
schedules and alerts, capture food consump-                                                                     BMI Tracker Graph
tion and exercise patterns and record vitals and                                                 21.91
                                                                           BMI Value




                                                                                                  21.9
symptoms. It also offers hooks for connecting to                                                 21.89
                                                                                                 21.88                                                      < 30
social networks such as Twitter and Facebook.                                                    21.87
Salubris provides learning materials to motivate                                                 21.86
                                                                                                          JFM      AMJ   JAS               OND
customers to understand their conditions scien-
tifically. The architecture is depicted in Figure 3.                                                     Vision                                  Appetite
                                                                                                                          Increasing
                                                                        Increasing




As the consumer records information about his
or her dietary patterns, exercise, symptoms and
                                                                                                 JFM AMJ JAS OND                         JFM AMJ JAS OND
medication compliance, the data is sent to the
                                                                                                  < 30                                    < 30
back-end server, from which the consumer can
opt to store it in an electronic health record
                                                                                                  Thirsty Feeling                  Urge for Urination
format. What is of interest is the ability to mine
                                                                          Increasing




                                                                                                                            Increasing




the data for aggregated trends from the server.
For example, a trend analysis can be drawn up
for a particular age group for body mass index                                                   JFM AMJ JAS OND                          JFM AMJ JAS OND
(BMI) and blood glucose values over a year’s                                                     < 30                                     < 30
time against reported symptoms of appetite,
feeling of thirst, urge for urination and vision
(see Figure 4).                                                    Figure 4



                         cognizant 20-20 insights                  4
as well; for instance, it will be possible to relate       for physicians, accounting for 41% of their mobile
a symptom — say, the worsening of eyesight for             usage.8 Web sites like WebMD provide very good
a diabetes patient — to lack of compliance with a          information; however, accessing this information
prescribed drug. This is an exciting possibility for       from mobile browsers is not always an enjoyable
all: consumers to manage their health, payers for          experience.
evidence and pharmaceuticals firms for whether
the drug benefits are realized.                            Pharmaceutical companies are creating summa-
                                                           ries from their educational information in easy-to-
Reincarnation of Information Dissemination                 use native mobile applications. The various types
Web Sites as Consumable Mobile Apps                        of information, such as 3-D diagrams, news, jour-
The need to access important, timely, concise              nals, calculators, etc., are subscription-controlled
and relevant medical information is extremely              and available in different languages for end users.
important for both physicians and consumers. A             Search is an essential feature in applications of
recent study by Manhattan Research shows that              this nature. The flow diagram in Figure 5 illus-
accessing clinical or medical information is one of        trates the contours of this application.
the top three most-used mobile medical functions


Realizing Information Portlets as Mobile Apps




                                                                                        Country Users
                                                                                          Various
                Structural       Content      Language         Subscription
                 Library          Hub        Translation         Control



Figure 5


Content Managed as Capsules


               Journals

                                                                                      iPad/iPhone/iPod
            Risk Calculators

                                                     Managed Content                  Windows Phone
                Forums
                                                       Backbone

             Health Videos                                                                  Android

             Care Contacts



Figure 6


Figure 6 provides an expanded view of the content          Crystal-Balling the Future
managed.
                                                           Today, pharmaceuticals companies monitor online
Native mobile features of touch, location and              sites for opinion and brand perception. In the
imaging functions are put to creative use in these         not-too-distant future, brand perception will be
applications. This will result in an innovative,           created and shared from mobile channels, as well.
immersive and more satisfying user experience              We expect new applications from pharmaceuticals
and will serve as an enticement to use mobile              companies offering an innovative and engaging
channels for accessing information.                        experience that facilitates the generation and



                          cognizant 20-20 insights         5
sharing of the customer voice. Applications of          Mobile channels offer the best passage for phar-
this nature will have wellness management func-         maceuticals companies to gain an understanding
tionality enabling consumers to take charge of          of the consumer. This trend will strengthen over
their health and well-being.                            the next few years. The consumer is the common
                                                        interest for the ecosystem of pharmaceuticals,
Managed care is on the verge of transformation.         care providers and payers; we are set to witness
Alerts that are indicative of serious conditions        the launch of well-amalgamated, innovative
emanating from implanted devices will be instan-        mobile applications covering all dimensions from
taneously routed to a mobile application, which         the consumer perspective.
will be specifically designed to handle this type of
situation. The physician who is using the mobile        By way of caution, we must add that there are
application will immediately arrange for the right      some genuine concerns that one needs to address
care for the consumer.                                  to make the mobile experience an irreversible
                                                        reality:
Mobile devices will emerge as the single system
of record for the consumer. The consumer will be        •   Security concerns related to the wireless trans-
able to walk into a physician office and just hand          mission of data. It is important to safeguard
over his device, which will contain information on          consumer interests and ensure that data
all the details of his or her eating habits, exercise       sharing happens with informed consent.
patterns, symptoms, medical history, etc. The
physician will simply pull out the required infor-
                                                        •   Portability of mobile applications across
                                                            mobile devices and the need for the evolution
mation and correlate it with the verbal observa-            of widely accepted standards.
tions of the consumers. This will enable better
targeted care and ultimately prove beneficial for       •   Regulatory concerns around the best level of
all parties.                                                engagement with consumers.

Mobile devices are more ubiquitous in developing
                                                        •   Controlling the proliferation of apps, as well as
                                                            creating a mechanism to find and design the
markets than in developed markets. Users in                 most worthwhile ones and rate them as such.
emerging markets are more comfortable with and
enthusiastic about using mobile devices.9 Though        There are concerted efforts to address the above
this appears seemingly simple, it has profound          concerns. We are sure they will be addressed
implications for pharmaceuticals companies.             in the near future and that the full potency of
Where traditionally it has been difficult to gain       the mobile revolution will be within reach of
an understanding of consumers, it can now be            consumers. Some suggestions for future work in
much more easily achieved in emerging markets,          this direction are:
given the eagerness to use and penetration of
the mobile devices. Thus, using mobile channels,        •   Architect applications to evaluate the effec-
                                                            tiveness of the mobility channel.
emerging markets can be understood much better
than developed markets. Pharmaceutical innova-          •   Monitor regulatory guidelines on pharmaceuti-
tions in customer understanding are more likely             cal and consumer interactions, as they greatly
to emerge from developing countries, and we can             influence pharmaceutical sales.10 Regulators’
expect new mobile applications targeted to local            interests are closely aligned to that of the
markets.                                                    consumer, so it’s vital to create innovative
                                                            applications designed for greater transpar-
Conclusion and Future Work                                  ency with regulators.
The above are some examples where we are                •   Use powerful capabilities in mobile devices
closely involved. These hand-picked examples                such as photography and location awareness
illustrate the alignment efforts of pharmaceu-              for creating applications that will help those
ticals companies with their customers. There                who may be in urgent need for care.
are a lot of applications in Apple’s iStore that
offer health-related services, from tracking            •   Repurpose innovations in educational and
                                                            retail-oriented mobile applications for phar-
one’s dietary behavior, to registering symptoms,
                                                            maceutical customers.
to physician/consumer educational materials.




                        cognizant 20-20 insights        6
Footnotes
1
     Wikipedia pharmaceutical industry definition. http://en.wikipedia.org/wiki/Pharmaceutical_industry
2
     Cliff Mintz, “Social Media’s Impact on Clinical Trials Enrollment,” Life Science Leader, November 2010.
     http://www.lifescienceleader.com/index.php?option=com_jambozine&layout=article&view=page&aid=
     4136
3
     Novartis Glivec Web site. http://www.glivec.com/index.jsp
4
     Jonna Häkkilä and Jani Mäntyjärvi, “Developing Design Guidelines for Context-Aware Mobile Applica-
     tions,” Proceedings of the 3rd International Conference on Mobile Technology, Applications & Systems,
     2006.
5
     Stefan Saroiu and Alec Wolman, “Enabling New Mobile Applications with Location Proofs,” Proceedings of
     the 10th Workshop on Mobile Computing Systems and Applications, 2009.
6
     Manhattan Research. http://www.manhattanresearch.com/
7
     Tim O’Reilly, “What is Web 2.0?” O’Reilly, Sept. 30, 2005.
     http://oreilly.com/web2/archive/what-is-web-20.html
8
     MarketResearch Web site. http://www.marketresearch.com
9
     “Measuring the Information Society: The ICT Development Index,” International Telecommunication
     Union, 2009.
10
     Stefan Stremersch and Aurelie Lemmens, “Sales Growth of New Pharmaceuticals Across the Globe:
     The Role of Regulatory Regimes,” Marketing Science, Vol 28, No. 4, July 2009, pp 690-708.




About the Author
Raghuraman Krishnamurthy is a Chief Architect in Cognizant’s Life Sciences Business Unit’s Technology
Consulting Group. Raghu’s core skills include enterprise architecture, social media, SOA, mobility appli-
cations and convergence of technologies. He has worked with several major pharmaceuticals in envi-
sioning and leading transformational initiatives. He has presented papers at numerous conferences and
was recently named a senior member of the prestigious Association of Computing Machinery (ACM).
Raghu holds a master’s degree from the Indian Institute of Technology, Mumbai, and is a TOGAF-certified
enterprise architect. He can be reached at Raghuraman.krishnamurthy2@cognizant.com.

Saikumar Jagannathan is a Chief Architect and heads Cognizant’s Life Sciences Business Unit’s
Technology Consulting Group. Sai is very passionate about technology and the life sciences industry.
His views and advice are frequently sought after by major pharmaceuticals. Sai’s recent areas of focus
are cloud computing and mobility and its transformational potential in the pharmaceutical space.
Sai is a TOGAF certified enterprise architect and specializes in building enterprise views of applica-
tions, large-scale architectures and performance tuning. Sai actively works on strategizing the latest
technology advances for possible business benefits for clients and prospects. He can be reached at
Saikumar.jagannathan@cognizant.com.



Acknowledgments
The authors would like to express their thanks to Srivatsan Nagaraja, Senior Vice President in Cogni-
zant’s Life Sciences Practice, for his thoughtful comments and insights. We express our gratitude to
Sairamkumar Jayaraman, Vice President in Cognizant’s Life Sciences Practice, for constantly supporting
us and encouraging us to think ahead. Our thanks are due to Dr. Elby Nash, Director of Cognizant’s Life
Sciences Practice, for several stimulating discussions that influenced our perspective.

Content used in this white paper was originally presented at the IEEE’s Tenth International Conference
on Mobile Business and published on the IEEE’s portal, http://www.computer.org/portal/web/csdl/
doi/10.1109/ICMB.2011.28. It is reprinted with the permission of the IEEE.


                          cognizant 20-20 insights          7
About Cognizant
Cognizant (NASDAQ: CTSH) is a leading provider of information technology, consulting, and business process out-
sourcing services, dedicated to helping the world’s leading companies build stronger businesses. Headquartered in
Teaneck, New Jersey (U.S.), Cognizant combines a passion for client satisfaction, technology innovation, deep industry
and business process expertise, and a global, collaborative workforce that embodies the future of work. With over 50
delivery centers worldwide and approximately 130,000 employees as of September 30, 2011, Cognizant is a member of
the NASDAQ-100, the S&P 500, the Forbes Global 2000, and the Fortune 500 and is ranked among the top performing
and fastest growing companies in the world. Visit us online at www.cognizant.com or follow us on Twitter: Cognizant.



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© Copyright 2011, Cognizant. All rights reserved. No part of this document may be reproduced, stored in a retrieval system, transmitted in any form or by any
means, electronic, mechanical, photocopying, recording, or otherwise, without the express written permission from Cognizant. The information contained herein is
subject to change without notice. All other trademarks mentioned herein are the property of their respective owners.

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Getting Closer to Customers: Mobility Revolution in Pharmaceuticals

  • 1. • Cognizant 20-20 Insights Getting Closer to Customers: Mobility Revolution in Pharmaceuticals Executive Summary focus on patients over the years. The situation is accentuated by the specific nature of the The mobile revolution has irrevocably changed the pharmaceutical industry. Consider the following: way the world communicates. The initial contours of this change were felt in the social dimension, where communication barriers between individu- • A huge amount of money is spent on inventing very few products, with perhaps one major als were eased. Over time, fueled by fertile minds, drug launched every couple of years or so. the contours extended to the business dimension, where greater effectiveness was achieved • Consumers are not the decision-makers, and by establishing a personal connection with it’s very hard to directly reach them. customers, which hitherto was almost impossible • Reaching the influencers is increasingly in some industry segments, such as pharmaceu- difficult, with more oversight by regulators. ticals. Payers are increasingly exerting decisive influence over the success of the product. This paper looks at how the mobile revolution is transforming the pharmaceutical industry by • Ethical concerns surround how drugs are enabling a consumer-to-industry connection. It tested in clinical and pre-clinical stages. proceeds to give a glimpse of the transforma- • Over-the-shoulder regulatory supervision tion by discussing three real-life examples and exists in almost all activities. concludes with a discussion on future trends and challenges. Pharmaceutical products reach consumers mostly through their prescribing physician. The Industry Challenges commercial focus has been predominantly on Pharmaceuticals companies are in the business figuring out how to encourage physicians to of offering products that save lives and enhance prescribe more of their products. It is estimated quality of life. Undeniably, the innovations of phar- that $19 billion is spent by pharmaceuticals maceuticals have helped millions of people lead companies on drug promotion in the U.S., alone.1 dignified lives. Our healthy future is predicated on Several key applications have been built by all our ability to access required medicinal products. pharmaceuticals companies to try to understand With increasing preference for generics over physician prescribing patterns, ways to ethi- branded drugs, the pharmaceutical industry is cally influence prescribers, types of marketing facing severe revenue pressure. This, coupled campaigns targeting select prescribers in select with other industry forces like managing payers territories, etc. Similarly, applications that and regulatory authorities, has diluted the monitor drug safety, help with drug discovery cognizant 20-20 insights | november 2011
  • 2. and track interactions with regulators have also engage with physicians. Manhattan Research been built. However, it would be surprising to find estimates that about 81% of physicians will any application that directly talks about consum- own smartphone devices by 2012.6 This mobile ers and their opinion of the product, partly due revolution has come as a silver lining, offering to the peculiar nature of the industry. Building new ways to engage with physicians. New mobility a better understanding of customer sentiments applications target not only the traditional sales and consumer experiences with any pharmaceu- force but also the patient community by offering tical product has been made very difficult by the wellness-based, informative applications. lack of direct customer access. The onset of social media, coupled with emerging channels, has Emerging channels such as Web portals and introduced a welcome change in this direction. mobile devices enable consumers with the latest information about pharmaceutical products. Social media and emerging channels for interac- Social networks empower consumers by forming tion have opened pathways for better connec- a community. Offering opinions and hearing tions to both patients and physicians. According advice from more experienced consumers is now to recent estimates, Facebook has more than a reality. This can improve or mar the chances of 500 million subscribers, and Twitter recently sur- success for pharmaceutical products. With every passed 190 million users (who tweet 65 million passing day, the increasing consumer influence times per day).2 Mining from social networking on pharmaceuticals is felt. sites, one can get a wealth of information, from recruiting for clinical trials, to figuring out active In his classic work on Web 2.0,7 Tim O’Reilly physicians and their preferences. Pharmaceuti- observes with great foresight that harnessing cal companies are conscious of the emergence collective intelligence is about “users themselves of new power centers and the gravity shifts. For deciding what is important for them rather than more effective connections with their consumer a few people in a back room deciding what is community, these companies are supporting important for users.” Of course, the context of brand Web sites, which provide a host of informa- this remark was that of Web page rankings, but tion about the product. One of the most success- we can see the extension of this thought mani- ful instances is Novartis’s Glivec Web sites,3 which festing itself in the form of “harnessing collecting provide a lot of useful consumer information. intelligence” elsewhere. In the context of the pharmaceutical industry, we see the following The Mobile Revolution: uses for collective intelligence: The Pharma Impact Tectonic shifts in technology innovations open up • Payer community: Direct evidence from consumers on their perception of the efficacy innovative avenues to capitalize on these changes of pharmaceutical products. and improve human life. Ubiquitous, affordable, easy-to-use mobile devices are probably the most • Pharmaceutical: The ability to hear the significant technology innovation to occur in the customer voice directly and gain valuable past few years. “Hyper-connection” is the order of insights from it. the day, and the trend is irreversible. Unimagined • Consumers: The ability to influence the future possibilities are now on the verge of realization, of pharmaceutical products. due to the wide prevalence of mobile devices and formation of virtual communities. With interest- The mobile revolution has given power to the ing research happening in the areas of location- average Joe to generate opinions and increase aware 4 and context-aware5 mobile applications, his social networking possibilities. This increase in pharmaceuticals companies will be able to touch social networking traffic requires elastic storage the lives of their consumers in novel and fruitful and processing capabilities. Cloud solutions ways. provide the right kind of infrastructure for intel- ligence generation. One can see the link between Access to physicians for pharmaceuticals sales mobile applications, social networks and cloud executives is increasingly becoming a challenge. solutions. There are interesting applications Physicians are shifting to more convenient that pharmaceuticals can create for monitoring channels for interaction such as the Web, which health conditions via an implanted device and a offers the flexibility of being available anytime physician’s mobile device, which can change the with the most recently updated information. contour of care beyond the known boundaries of Pharmaceuticals are forced to find new ways to today. cognizant 20-20 insights 2
  • 3. Mobile App for Consumer-Physician-Payer Connection Consumer This app enables a channel of Higher customer satisfaction will positively interaction, aimed at customer care. influence the payer, resulting in more business for pharmaceuticals. Physician Payer Figure 1 We studied the popular applications developed advances, pharmaceuticals are experimenting by pharmaceuticals that are targeted toward with novel mobile applications that can notify the consumers. In parallel, we also looked at the inter- physician about the consumer’s health instanta- esting mobile applications available in the public neously. This application enables the physician domain pertaining to healthcare. With these, to work even when he is not in the office. Such a we identified the broad themes and picked out capability transcends the constraints of time and mobility applications in which these themes were space, demonstrating customer care practically well-expressed. We will describe three such appli- anytime, anywhere. Figure 1 illustrates how the cations that are illustrative of the technology and application fits in the pharmaceutical-consumer- domain trends. physician chain. Three Real-Life Examples The simplified flow of this application is depicted Pharmaceuticals are motivated by the desire to in Figure 2. improve consumer health and well-being. The mobile revolution has enabled computing power Automatic Transmission of Alerts in mobile devices, and pharmaceuticals are taking from Consumers to Care Providers advantage of that to improve consumer health. The examples below are linked by this common theme: how to use the mobile revolution to improve consumer satisfaction and enable higher quality of life. We will see how each of these Implanted Transmissions manifests this theme in innovative ways. Device Database Remote Patient Monitoring The market for medical devices is growing briskly. Alerts Market size for medical devices in the U.S. was Generator about $94.9 billion in 2010.8 Medical devices are capable of automatically transmitting the health conditions of the consumer to the physician, Mobile Push Apps Notification who uses this information to assess the patient’s Server health. Currently, this is mostly being done by logging on to a Web site and viewing the transmis- sions or using hard copies, both of which generally introduce a time lag. Exploiting the technological Figure 2 cognizant 20-20 insights 3
  • 4. The Salubris Ecosystem REST End Users Calls iPhone/iPad Web Services Rx (prescription details) Care Provider Android Web Application Logs into wellness application and provisions device to patients Blackberry Multitenant Provisioning ETL Analytic Insight Warehouse 1. Correlation between exercise and mood level 2. Analytics between blood glucose vs.stress 3. ..... EMR Google/MS HV Health Info Exchange Figure 3 Salubris: A Wellness Framework Such a correlation will help in establishing Wellness — whose responsibility is it? The consum- evidence of whether the drug worked as expected. ers? Pharmaceuticals? Physicians? Ultimately, It is of invaluable help for the payer community, wellness is the consumer’s responsibility, and the entire ecosystem can and should help the con- Correlation of Vitals to Symptoms sumer achieve it. The seed idea of the Salubris Blood Glucose Tracker Graph Blood Glucose Value platform is using mobility technology to empower patients to take charge of their wellness and, in 40 the process, generate real-world evidence to help 30 < 30 both pharmaceuticals and the payer community. 20 10 JFM AM J JAS OND Salubris provides the ability to set medication schedules and alerts, capture food consump- BMI Tracker Graph tion and exercise patterns and record vitals and 21.91 BMI Value 21.9 symptoms. It also offers hooks for connecting to 21.89 21.88 < 30 social networks such as Twitter and Facebook. 21.87 Salubris provides learning materials to motivate 21.86 JFM AMJ JAS OND customers to understand their conditions scien- tifically. The architecture is depicted in Figure 3. Vision Appetite Increasing Increasing As the consumer records information about his or her dietary patterns, exercise, symptoms and JFM AMJ JAS OND JFM AMJ JAS OND medication compliance, the data is sent to the < 30 < 30 back-end server, from which the consumer can opt to store it in an electronic health record Thirsty Feeling Urge for Urination format. What is of interest is the ability to mine Increasing Increasing the data for aggregated trends from the server. For example, a trend analysis can be drawn up for a particular age group for body mass index JFM AMJ JAS OND JFM AMJ JAS OND (BMI) and blood glucose values over a year’s < 30 < 30 time against reported symptoms of appetite, feeling of thirst, urge for urination and vision (see Figure 4). Figure 4 cognizant 20-20 insights 4
  • 5. as well; for instance, it will be possible to relate for physicians, accounting for 41% of their mobile a symptom — say, the worsening of eyesight for usage.8 Web sites like WebMD provide very good a diabetes patient — to lack of compliance with a information; however, accessing this information prescribed drug. This is an exciting possibility for from mobile browsers is not always an enjoyable all: consumers to manage their health, payers for experience. evidence and pharmaceuticals firms for whether the drug benefits are realized. Pharmaceutical companies are creating summa- ries from their educational information in easy-to- Reincarnation of Information Dissemination use native mobile applications. The various types Web Sites as Consumable Mobile Apps of information, such as 3-D diagrams, news, jour- The need to access important, timely, concise nals, calculators, etc., are subscription-controlled and relevant medical information is extremely and available in different languages for end users. important for both physicians and consumers. A Search is an essential feature in applications of recent study by Manhattan Research shows that this nature. The flow diagram in Figure 5 illus- accessing clinical or medical information is one of trates the contours of this application. the top three most-used mobile medical functions Realizing Information Portlets as Mobile Apps Country Users Various Structural Content Language Subscription Library Hub Translation Control Figure 5 Content Managed as Capsules Journals iPad/iPhone/iPod Risk Calculators Managed Content Windows Phone Forums Backbone Health Videos Android Care Contacts Figure 6 Figure 6 provides an expanded view of the content Crystal-Balling the Future managed. Today, pharmaceuticals companies monitor online Native mobile features of touch, location and sites for opinion and brand perception. In the imaging functions are put to creative use in these not-too-distant future, brand perception will be applications. This will result in an innovative, created and shared from mobile channels, as well. immersive and more satisfying user experience We expect new applications from pharmaceuticals and will serve as an enticement to use mobile companies offering an innovative and engaging channels for accessing information. experience that facilitates the generation and cognizant 20-20 insights 5
  • 6. sharing of the customer voice. Applications of Mobile channels offer the best passage for phar- this nature will have wellness management func- maceuticals companies to gain an understanding tionality enabling consumers to take charge of of the consumer. This trend will strengthen over their health and well-being. the next few years. The consumer is the common interest for the ecosystem of pharmaceuticals, Managed care is on the verge of transformation. care providers and payers; we are set to witness Alerts that are indicative of serious conditions the launch of well-amalgamated, innovative emanating from implanted devices will be instan- mobile applications covering all dimensions from taneously routed to a mobile application, which the consumer perspective. will be specifically designed to handle this type of situation. The physician who is using the mobile By way of caution, we must add that there are application will immediately arrange for the right some genuine concerns that one needs to address care for the consumer. to make the mobile experience an irreversible reality: Mobile devices will emerge as the single system of record for the consumer. The consumer will be • Security concerns related to the wireless trans- able to walk into a physician office and just hand mission of data. It is important to safeguard over his device, which will contain information on consumer interests and ensure that data all the details of his or her eating habits, exercise sharing happens with informed consent. patterns, symptoms, medical history, etc. The physician will simply pull out the required infor- • Portability of mobile applications across mobile devices and the need for the evolution mation and correlate it with the verbal observa- of widely accepted standards. tions of the consumers. This will enable better targeted care and ultimately prove beneficial for • Regulatory concerns around the best level of all parties. engagement with consumers. Mobile devices are more ubiquitous in developing • Controlling the proliferation of apps, as well as creating a mechanism to find and design the markets than in developed markets. Users in most worthwhile ones and rate them as such. emerging markets are more comfortable with and enthusiastic about using mobile devices.9 Though There are concerted efforts to address the above this appears seemingly simple, it has profound concerns. We are sure they will be addressed implications for pharmaceuticals companies. in the near future and that the full potency of Where traditionally it has been difficult to gain the mobile revolution will be within reach of an understanding of consumers, it can now be consumers. Some suggestions for future work in much more easily achieved in emerging markets, this direction are: given the eagerness to use and penetration of the mobile devices. Thus, using mobile channels, • Architect applications to evaluate the effec- tiveness of the mobility channel. emerging markets can be understood much better than developed markets. Pharmaceutical innova- • Monitor regulatory guidelines on pharmaceuti- tions in customer understanding are more likely cal and consumer interactions, as they greatly to emerge from developing countries, and we can influence pharmaceutical sales.10 Regulators’ expect new mobile applications targeted to local interests are closely aligned to that of the markets. consumer, so it’s vital to create innovative applications designed for greater transpar- Conclusion and Future Work ency with regulators. The above are some examples where we are • Use powerful capabilities in mobile devices closely involved. These hand-picked examples such as photography and location awareness illustrate the alignment efforts of pharmaceu- for creating applications that will help those ticals companies with their customers. There who may be in urgent need for care. are a lot of applications in Apple’s iStore that offer health-related services, from tracking • Repurpose innovations in educational and retail-oriented mobile applications for phar- one’s dietary behavior, to registering symptoms, maceutical customers. to physician/consumer educational materials. cognizant 20-20 insights 6
  • 7. Footnotes 1 Wikipedia pharmaceutical industry definition. http://en.wikipedia.org/wiki/Pharmaceutical_industry 2 Cliff Mintz, “Social Media’s Impact on Clinical Trials Enrollment,” Life Science Leader, November 2010. http://www.lifescienceleader.com/index.php?option=com_jambozine&layout=article&view=page&aid= 4136 3 Novartis Glivec Web site. http://www.glivec.com/index.jsp 4 Jonna Häkkilä and Jani Mäntyjärvi, “Developing Design Guidelines for Context-Aware Mobile Applica- tions,” Proceedings of the 3rd International Conference on Mobile Technology, Applications & Systems, 2006. 5 Stefan Saroiu and Alec Wolman, “Enabling New Mobile Applications with Location Proofs,” Proceedings of the 10th Workshop on Mobile Computing Systems and Applications, 2009. 6 Manhattan Research. http://www.manhattanresearch.com/ 7 Tim O’Reilly, “What is Web 2.0?” O’Reilly, Sept. 30, 2005. http://oreilly.com/web2/archive/what-is-web-20.html 8 MarketResearch Web site. http://www.marketresearch.com 9 “Measuring the Information Society: The ICT Development Index,” International Telecommunication Union, 2009. 10 Stefan Stremersch and Aurelie Lemmens, “Sales Growth of New Pharmaceuticals Across the Globe: The Role of Regulatory Regimes,” Marketing Science, Vol 28, No. 4, July 2009, pp 690-708. About the Author Raghuraman Krishnamurthy is a Chief Architect in Cognizant’s Life Sciences Business Unit’s Technology Consulting Group. Raghu’s core skills include enterprise architecture, social media, SOA, mobility appli- cations and convergence of technologies. He has worked with several major pharmaceuticals in envi- sioning and leading transformational initiatives. He has presented papers at numerous conferences and was recently named a senior member of the prestigious Association of Computing Machinery (ACM). Raghu holds a master’s degree from the Indian Institute of Technology, Mumbai, and is a TOGAF-certified enterprise architect. He can be reached at Raghuraman.krishnamurthy2@cognizant.com. Saikumar Jagannathan is a Chief Architect and heads Cognizant’s Life Sciences Business Unit’s Technology Consulting Group. Sai is very passionate about technology and the life sciences industry. His views and advice are frequently sought after by major pharmaceuticals. Sai’s recent areas of focus are cloud computing and mobility and its transformational potential in the pharmaceutical space. Sai is a TOGAF certified enterprise architect and specializes in building enterprise views of applica- tions, large-scale architectures and performance tuning. Sai actively works on strategizing the latest technology advances for possible business benefits for clients and prospects. He can be reached at Saikumar.jagannathan@cognizant.com. Acknowledgments The authors would like to express their thanks to Srivatsan Nagaraja, Senior Vice President in Cogni- zant’s Life Sciences Practice, for his thoughtful comments and insights. We express our gratitude to Sairamkumar Jayaraman, Vice President in Cognizant’s Life Sciences Practice, for constantly supporting us and encouraging us to think ahead. Our thanks are due to Dr. Elby Nash, Director of Cognizant’s Life Sciences Practice, for several stimulating discussions that influenced our perspective. Content used in this white paper was originally presented at the IEEE’s Tenth International Conference on Mobile Business and published on the IEEE’s portal, http://www.computer.org/portal/web/csdl/ doi/10.1109/ICMB.2011.28. It is reprinted with the permission of the IEEE. cognizant 20-20 insights 7
  • 8. About Cognizant Cognizant (NASDAQ: CTSH) is a leading provider of information technology, consulting, and business process out- sourcing services, dedicated to helping the world’s leading companies build stronger businesses. Headquartered in Teaneck, New Jersey (U.S.), Cognizant combines a passion for client satisfaction, technology innovation, deep industry and business process expertise, and a global, collaborative workforce that embodies the future of work. With over 50 delivery centers worldwide and approximately 130,000 employees as of September 30, 2011, Cognizant is a member of the NASDAQ-100, the S&P 500, the Forbes Global 2000, and the Fortune 500 and is ranked among the top performing and fastest growing companies in the world. Visit us online at www.cognizant.com or follow us on Twitter: Cognizant. World Headquarters European Headquarters India Operations Headquarters 500 Frank W. Burr Blvd. 1 Kingdom Street #5/535, Old Mahabalipuram Road Teaneck, NJ 07666 USA Paddington Central Okkiyam Pettai, Thoraipakkam Phone: +1 201 801 0233 London W2 6BD Chennai, 600 096 India Fax: +1 201 801 0243 Phone: +44 (0) 20 7297 7600 Phone: +91 (0) 44 4209 6000 Toll Free: +1 888 937 3277 Fax: +44 (0) 20 7121 0102 Fax: +91 (0) 44 4209 6060 Email: inquiry@cognizant.com Email: infouk@cognizant.com Email: inquiryindia@cognizant.com © Copyright 2011, Cognizant. All rights reserved. No part of this document may be reproduced, stored in a retrieval system, transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the express written permission from Cognizant. The information contained herein is subject to change without notice. All other trademarks mentioned herein are the property of their respective owners.