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Excretion
• Homeostasis is the maintenance of a
stable internal environment
– in cells
– in the tissue fluid around the cells
– in the blood plasma
• For example:
– Temperature
– Water
– Glucose
negative feedback mechanisms
• Excretion is the removal, from the body, of
unwanted waste from metabolic reactions
• For example:
– CO2 from respiration in all body cells is
carried by the blood to the lungs and excreted
– Urea from the deamination of excess
Deamination
Excretory System
Kidney: external view
Adrenal gland
Cortex
Renal artery – brings blood in
Pelvis – continues into ureter
Renal vein – removes blood
Ureter – urine to bladder
Kidney: section
Capsule – tough outer layer
Renal sinus – continues to pelvis
Renal pelvis – continuous with
ureter
Renal pyramid – part of medulla
Medulla – mostly collecting ducts
Cortex – glomeruli are found here
Renal Cortex
This is where
the kidney
nephrons are
found
There is a rich
supply of
capillaries
Detail of nephron
Nephrons are long tubes
that start at a Bowman’s
capsule and finally flow into
the pelvis of the kidney
Nephron
Renal Artery
blood comes in rich in urea
Glomerulus
This is a knot of capillaries Water and
solutes are forced out
Bowman’s capsule
The filtrate flows into this
capsule
Proximal Convoluted Tubule
All the glucose, amino acids and
some water and salts move back
into the blood here
Peritubular capillaries
These surround the tubules
and pick up substances from
the filtrate
Loop of Henle
This is important in re-
absorption of water
Distal covoluted tubules
Na+ is reabsorbed here
Collecting duct
More water is
reabsorbed and
osmoregulation
happens here
Urine
Leaves
the
kidney,
Removing
urea and
excess
salt and
water
Renal Vein
blood leaving the kidney has very little urea and
some of the salts and water removed

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1. excretion introduction