The document discusses the respiratory system's response to exercise. It notes that respiration is critical for maximal aerobic exercise performance. Ventilation increases abruptly at the start of exercise and more gradually thereafter. Arterial blood gases show increased oxygen demand is met by higher ventilation. Ventilation and heart rate both increase with exercise. The limits of ventilation are discussed as are changes in lung volumes and oxygen consumption during exercise.

1. RESPIRATORY RESPONSE TO EXERCISE by DIPAYAN SEN 3 RD YEAR MEDICAL COLLEGE, KOLKATA

6. Oxygen Consumption in Exercise (VO 2 max) CONDITIONS MAXIMAL OXYGEN CONSUMPTION (ml/min) Untrained average male 3600 Athletically trained average male 4000 Male marathon runner 5100

7. Limits Of Ventilation Abnormalities in the respiratory system Special conditions Exercise at high altitudes Exercise under very hot conditions Pulmonary Ventilation at maximal exercise 100-110 L/min Maximal Breathing Capacity 150-170 L/min

8. Changes In Ventilation During Exercise The pO 2 of arterial blood drops from 40mm to <25mm Hg Blood flow per min rises from 5.5 L/min to 20-35 L/min Recruitment of new capillaries at tissue level Increased O 2 delivery to tissues

11. Arterial blood gases during exercise

12. Increase in ventilation Increased oxygen demand Increased body temperature Increased plasma potassium levels Increased neural sensitivity to partial pressure of CO 2 Increased plasma H + ion concentration Role of O 2 ???

13. Mainly shows increase in both rate and depth of respiration Mainly shows increase in depth of respiration Exercise Moderate exercise Severe exercise

14. Ventilation and heart rate with exercise

15. Oxygen Debt Replenishment of ATP Removal of lactic acid Replenishment of myoglobin with O 2 Replenishment of glycogen

16. VENTILATION RATE

17. Excess Post-exercise Oxygen Consumption

19. Maximal O 2 diffusing capacity of different persons Nonathlete at rest 23 mL/min Nonathlete during maximal exercise 48 mL/min Speed skaters during maximal exercise 64 mL/min Swimmers during maximal exercise 71 mL/min Oarsman during maximal exercise 80 mL/min

21. Oxygen-Haemoglobin Dissociation Curve in Exercise ........... CURVE IN EXERCISE ……… . NORMAL CURVE

23. Effect of Smoking on Pulmonary Ventilation in Exercise SMOKING (Nicotine and other irritants) Constriction of the terminal bronchioles Increases the resistance of airflow Increased fluid secretion and mucosal oedema Paralyses the mucociliary escalator system

24. Increased Airway Resistance Decreased expiratory flow Chronic smoking Chronic Obstructive Pulmonary Disease (COPD)

25. COPD Chronic bronchitis (Excessive mucous blocks airways) Emphysema (Dilatation of alveolar sacs, airway collapse and increased resistance)

26. Smoking is equivalent to suicide… Please try to quit smoking…

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