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2021 Alfred Research Alliance Honours and postgraduate research information evening

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2021 Alfred Research Alliance Honours and postgraduate research information evening

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Find out more about Honours and graduate research at the Alfred Research Alliance, featuring the research powerhouses of Monash University Central Clinical (CCS) and Public Health and Preventive Medicine (SPHPM) schools, and the Baker and Burnet research institutes.

Find out more about Honours and graduate research at the Alfred Research Alliance, featuring the research powerhouses of Monash University Central Clinical (CCS) and Public Health and Preventive Medicine (SPHPM) schools, and the Baker and Burnet research institutes.

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2021 Alfred Research Alliance Honours and postgraduate research information evening

  1. 1. MONASH CENTRAL CLINICAL SCHOOL MONASH SCHOOL OF PUBLIC HEALTH & PREVENTIVE MEDICINE Honours and Graduate Research at Alfred Research Alliance Wednesday 11th August 2021 Information Evening CCS and SPHPM
  2. 2. Acknowledgment to Country
  3. 3. Dean, Sub-Faculty Public Health and Translational Medicine, Monash University Director of Research, The Alfred Professor Stephen Jane
  4. 4. Public Health & Translational Medicine – where your research matters biomarkers drug discovery devices clinical trials clinical registries population studies occupational & environmental health health economics basic science translational research
  5. 5. Central Clinical School School of Public Health and Preventive Medicine Who are we?
  6. 6. Honours coordinators: Prof Christoph Hagemeyer(CCS) A/Prof Margaret Hibbs (CCS) Dr Vilija Jokubaitis (CCS) Prof Danny Liew (SPHPM) A/Prof Joanne Ryan (SPHPM) Dr Darshini Ayton (SPHPM) Who should you talk to?
  7. 7. Alfred Surrounds
  8. 8. Clayton Surrounds
  9. 9. • An awesome experience! • Immersion in world-class research • Opportunity to make a difference • Training and mentoring by world-class researchers What will you gain?
  10. 10. What does ‘translational research’ mean? Why do it? Translational Research
  11. 11. • Alfred Research Alliance Scholarships x 2 ($6000) • www.monash.edu.au/study/scholarships/honours/ Scholarships
  12. 12. HOPE TO SEE YOU NEXT YEAR MONASH CENTRAL CLINICAL SCHOOL MONASH SCHOOL OF PUBLIC HEALTH & PREVENTIVE MEDICINE
  13. 13. Event Co-Host Ms. Georgia Symons
  14. 14.  Zoom Webinar 6:00PM – 7:30PM – Please note this will close at 7:30PM sharp  Use the Q&A Function on bottom of screen to ask general honours questions  Assigned moderators will answer your Qs – Dr. Vilija Jokubaitis (CCS Honours Coordinator) – Prof Robyn Slattery (Director of Education CCS) – Ms. Sharon Gurry (SPHPM student services)  For any future enquiries please email – ccs.honours@monash.edu – med-sphpm-honours@monash.edu Event Housekeeping - Webinar
  15. 15.  Departmental Q&A Zoom Meetings 7:30PM – 8:30PM – Individual zoom links sent via email, reposted in the chat – Ask verbal questions and also type your questions – Panel of enthusiastic academics in each of department  Attend as many Q&A sessions as you wish – Feel free to contact researchers directly if you are unable to catch a specific researcher of interest  Hope you enjoy the diverse research that will be shared tonight and it inspires you to come and join us as this great research precinct. Event Housekeeping: Departmental Q&A Zoom Meetings
  16. 16. Head, Central Clinical School Program Director, Alfred Brain Professor Terence O’Brien
  17. 17. biomarkers drug discovery devices clinical trials clinical registries outcomes research population studies occupational & environmental health health services research health economics Mechanisms of disease Imaging CCS SPHPM CCS: Translational Research
  18. 18. Neuroscience Musculoskeletal Diabetes Cardiology Haematology Infectious Diseases Trauma Mental Health Sexual Health Anaesthesia Immunology Respiratory Allergy Gastroenterology Women’s Health Ageing Critical Care Imaging Surgery CCS: What Diseases Do We Research?
  19. 19. Department/Centre & HOD Head of School Terry O’Brien ACBD/Haematology Harshal Nandurkar Anaesthesiology & PM Paul Myles Diabetes Mark Cooper Gastroenterology Alex Boussioutas Immunology & Path. David Tarlinton Infectious Diseases Anton Peleg Psychiatry Jayashri Kulkarni Renal Paul Lawton Respiratory Anne Holland MSHC Kit Fairley Medicine - Alfred Terry O’Brien Medicine - Peninsula Velandai Srikanth Oncology Mark Shackleton Neuroscience Helmut Butzkueven NTRI Mark Fitzgerald RACI Robyn O’Hehir Surgery & CORE Wendy Brown Med Education Anne Powell Education (non Med) Robyn Slattery Psychiatry Anaesthesiology & Perioperative Medicine CCS: School structure
  20. 20. •An awesome experience! •Immersion in world-class medical research environment •Embedded in specialist clinical hospital •Training and mentoring by world-class clinical & translational researchers – >30 NHMRC Investigator Grant Holders What will you get?
  21. 21. •Formal training in research methods •Publications What will you get?
  22. 22. Honours coordinators: Who should you talk to? Speak to potential supervisors: Webpage: https://www.monash.edu/medicine/ccs/education/future- students/honours Link to CCS project booklet: https://www.monash.edu/__data/assets/pdf_file/0004/2286634/2022- Hons-and-postgrad-project-booklet.pdf CCS Honours Student Services: E: ccs.honours@monash.edu Prof Christoph Hagemeyer(CCS) A/Prof Margaret Hibbs (CCS) Dr Vilija Jokubaitis (CCS)
  23. 23. MONASH MEDICINE, NURSING & HEALTH SCIENCES Director, Teaching and Learning Head, Medical Education Research and Quality (MERQ) unit School of Public Health and Preventive Medicine Professor Dragan Ilic
  24. 24.  BMedSci  BBiomed  BHealthSciences – 553 St Kilda Rd – MCHRI – VIFM  1,200 staff employed  $38 million average research income  783 average number of publications  #46 globally in preclinical and health sciences Honours at SPHPM
  25. 25.  ASPREE – Aspirin in the elderly, 14+ sub-studies (depression, cancer, genomics…)  Cancer – Registries, melanoma imaging and diagnosis  Clinical epidemiology – Infectious diseases, cardiovascular, musculoskeletal  Research methodology – Data sciences, analytics, Cochrane Opportunities across disciplines
  26. 26.  Health services – Registry science, transfusion/prostate/bariatric surgery…  Occupational and environmental health – Hazelwood health study  Critical care research – ANZIC-RC, pre-hospital/emergency/trauma research  Social sciences – Global and women’s health Opportunities across disciplines
  27. 27.  Metabolism, genomics and ageing – STAREE, diabetes and vascular medicine, ageing, public health genomics  Health professions education – Cost and value, pedagogical research  Monash Centre for Health Research and Implementation (MCHRI)  Department of Forensic Medicine Opportunities across disciplines
  28. 28. Careers in Public Health
  29. 29. The Honours Experience (CCS) Former Honours student Current PhD student Department of Immunology and Pathology Central Clinical School Ms. Alexandra Dvorscek
  30. 30. • Bachelor of Biomedical Science and Bachelor of Science – Majors: Immunology and Genetics and Molecular Biology – IMM3990- Jacobson laboratory (B cell and antibody memory) • 2019- Bachelor of Biomedical Science (Honours) – Tarlinton Laboratory (Immune Memory Laboratory) – Prof David Tarlinton & Dr Isaak Quast • 2020- PhD (translational research) – Immunology- Tarlinton Laboratory A little about me… Past Honours Experience
  31. 31. • Research project and coursework – Original research • Lab based, you will perform experiments and then present your data in a seminar and as a thesis • Whole new university experience • A lot of independence • Hard work but rewarding What is Honours? Past Honours Experience
  32. 32. • Meet with potential supervisors based on your interests/the projects offered • Ask about the lab work- make sure it’s something you could spend the year doing • Make sure you and your supervisor are on the same page – Hours, workload, communication, etc. • Speak to past/present students from that lab Choosing your project Past Honours Experience
  33. 33. • You will be left on your own – Your supervisor will help you learn all techniques you will use – Everyone around is really helpful and supportive • You’ll be expected to know everything – Not the case, you’ll be taught everything from square one – You’ll learn as you go (lab work/theory) • Honours takes over your life – If you’re organised, you can have a great work/life balance Misconceptions Past Honours Experience
  34. 34. Honours at ARA • Collaborative • Plenty of opportunities to learn about other topics (seminars, journal clubs) • Real lab experience • Great mix of staff and students • Opens up opportunities for the future • Great culture Past Honours Experience
  35. 35. Any further questions I’m happy for you to email me! Alexandra.Dvorscek@monash.edu Thank you! Past Honours Experience
  36. 36. The Honours Experience (SPHPM) Former Honours student Current PhD student Pre-hospital, Emergency and Trauma Research School of Public Health and Preventive Medicine Ms. Georgina Lau
  37. 37. • Bachelor of Biomedical Science • Honours -Patterns of personal responsibility for injury events • PhD -Alcohol and drug use in major trauma injury events Past Honours Experience A little about me…
  38. 38. • Year of research after your degree • An opportunity to give research a go • Transition year from university to the workplace Past Honours Experience What is Honours?
  39. 39. • Explore your options • Take the time to meet potential supervisors • Pick a topic that interests you Past Honours Experience Choosing your project
  40. 40. georgina.lau@monash.edu Past Honours Experience Contact
  41. 41. Deputy Head of Unit, Health and Social Care Unit School of Public Health and Preventive Medicine Dr Darshini Ayton
  42. 42. Acute and Critical Care - Prof Jamie Cooper & Prof Erica Wood Chronic Disease and Ageing – Prof Susan Davis & Prof Sophia Zoungas Forensic Medicine - A/Prof Richard Bassed & Prof Noel Woodford General Practice - Prof Danielle Maza Health Systems, Services and Policy - Prof Alex Collie & Prof Helena Teede Planetary Health - Prof Jane Fisher & Prof Karin Leder
  43. 43. Biostatistics, Data Analytics/Modelling & Health Economics - Prof Andrew Forbes & Prof Danny Liew Clinical & Health Data Outcomes Innovation and Research - Prof Susannah Ahern & Prof Belinda Gabbe Clinical Trials and Cohort Studies - Prof Michael Abramson & Prof Carol Hodgson Evidence Synthesis, Qualitative & Implementation Methods - Prof Sally Green & Prof Helen Skouteris Teaching & Learning - Prof Dragan Ilic & A/Prof Basia Diug
  44. 44. ✔ Randomised controlled trial ✔ Community-based trials ✔ Prospective studies ✔ Observational methods ✔ Patient experiences ✔ Epidemiology ✔ Biostatistics ✔ Big Data ✔ Qualitative research ✔ Mixed-methods research ✔ Systematic reviews ✔ Health economics ✔ Implementation research ✔ Clinical Practice Guidelines ✔ Health Policy SPHPM: Methods Applied
  45. 45. STAREE Clinical Trial  Ground breaking community-based trial of the effects of statins on health outcomes in older individuals.  Recruiting >10,000 participants aged 70+ years across Australia  Collecting information on numerous health outcomes, lifestyle and quality of life.  Contribute to this exciting study and join our team of clinicians, study managers, field officers, data officers, post doctoral researchers and PhD students. For further details: andrea.curtis@monash.edu Prof. Sophia Zoungas A/Prof. Ingrid Hopper Dr. Andrea Curtis
  46. 46. ASPREE Clinical Trials: Promoting healthy ageing in older individuals The impact of social isolation and loneliness Dr. Rosanne Freak-Poli Dementia risk prediction and epigenetic biomarkers A/Prof. Joanne Ryan How physical activity can modify health outcomes Dr. Danijela Gasevic
  47. 47. Critical Care Research: Pre-hospital, emergency and trauma  Perioperative performance variation in cardiac surgery  Recover from traumatic injury  Imaging for pyelonephritis in the Emergency Department  Emergency hospital admission critical bleeding  Drug & alcohol use in non-traffic trauma deaths  Evaluating interventions to prevent serious road traffic crashes  Nutrition during critical illnesses Examples of honours projects :
  48. 48. Perioperative Medicine: Clinical trials in anaesthesia and perioperative medicine Improving outcomes for patients having major surgery Examples of recent honours projects:  Chewing gum to treat nausea & vomiting  Chronic subdural haematoma outcomes Prof. Kate Leslie AO
  49. 49. Clinical Registries (30+) National Gynae-Oncology Registry  ovarian cancer outcomes Burns Registry of Australia & New Zealand  burns injuries during school holidays  profile of young adult patents with burn injuries Victorian Cardiac Outcomes Registry  time-trends in outcomes following Percutaneous Coronary Intervention (PCI)  management & outcomes of patients with Acute Coronary Syndrome Australian Cystic Fibrosis Data Registry  Patient reported outcomes in CF patients For further details: cheryl.grant@monash.edu
  50. 50. Multi-disciplinary team of clinicians and allied health staff, primary care practitioners, not-for- profit organisations, patients & caregivers. Integrate patient-reported outcomes into clinical care to improve:  quality of life  symptom burden and unmet needs  survival For further details: liane.ioannou@monash.edu Dr. Liane Ioannou Prof. John Zalcberg 3D imaging technology for:  early diagnosis of melanoma  surveillance of high-risk individuals A/Prof. Victoria Mar Cancer Research
  51. 51.  Circulating microRNA as biomarkers for CVD  Genetic variants modifying CVD risk  Impact of folic acid supplementation on CVD  Health Economic Assessment A/Prof.Ilana Ackerman Prof. Danny Liew Basic, clinical & epidemiological research Cardiovascular Disease
  52. 52. Research into the causes and treatment of arthritis and back pain For further details: jointstudy@monash.edu  Effect of obesity & physical inactivity on joint health  Testing new treatments for arthritis and low back pain using specialized medical imaging techniques  Inter-relationship between joint health & CV  Optimising outcomes following joint replacement Musculoskeletal Unit
  53. 53. For further information: jane.fisher@monash.edu Recent honours projects: Intimate partner violence during pregnancy in Vanuatu Social-economic development & pregnancy mental health in rural Vietnam Attitudes of young Sri Lankans in Australia towards mental health and accessing mental healthcare Our research is conducted in Australia and the Indo-Pacific region We generate evidence to explain health inequalities, & translate research to promote health and improve health services Global and Women’s Health
  54. 54.  Polycystic ovary syndrome  COVID-19 Behavioural research  Data driven healthcare  Health equity  Early menopause Chronic Disease, Diabetes & Metabolic Health Women’s & Children’s Public Health Implementation & Healthcare Improvement Research Methodologies & Support Monash Centre for Health Research and Implementation Prof. Helena Teede A/Prof. Jacqui Boyle
  55. 55.  Climate change, air pollution & environmental health  Links between air pollution and autism  Wind farms and human health  Do mobile phones affect cognitive development in children?  Firefighters’ Health Study  Asbestos cement workers Prof. Yuming Guo Climate and Environment: Monash Centre for Occupation and Environmental Health
  56. 56.  Relationship between medication use and functional recovery  Healthcare delivery & return to work trajectories  Quantify unique injury profile among educators  Geographic mapping of work disability in Australia  Impact of policy change and system shocks Dr. Shannon Gray Dr. Tyler Lane Insurance, Work and Health Group
  57. 57.  Estimation tuberculosis reactivation rates following exposure  Knowledge translation for stroke living guidelines  Interrupted time series studies in public health  Reproducibility & transparency in the synthesis of research findings  Medical Education Research & Quality (MERQ) unit Prof. Dragan Ilic Dr. Tari Turner Research Methodology: Biostatistics, Cochrane, Health Economics
  58. 58.  We integrate with industry partners across health and social care to produce knowledge, implement innovative programs and translate these into practice.  We are experts in implementation science and participatory, co-design research methods. Our research is mostly driven by an equity lens. Dr Briony Hill Prof. Helen Skouteris Health and Social Care Unit Dr Darshini Ayton Our research across health and social care improvement includes:  lifestyle health and wellbeing from preconception to adulthood;  early childhood education and care;  child and family welfare; parenting;  aged care and ageing.
  59. 59. https://www.monash.edu/medicine/sphpm/study/honours
  60. 60. Representative of Australian Centre for Blood Diseases Head, Division of Blood Cancer Research Professor David Curtis
  61. 61. Australian Centre for Blood Diseases Largest hospital-based translational haematology department in Australia Myeloma Leukaemia Myeloproliferative disorders Stem Cells Cancer and Immune Cell Signalling Thrombosis and Vascular Biology Nanoparticles Genetics & Epigenetics of Blood Cancers Research Personnel include 14 Laboratory Heads, 24 Fellows, 22 Research Assistants, 4 Honours and 25 PhD students
  62. 62. Australian Centre for Blood Diseases Why do Honours/PhD with Australian Centre for Blood Diseases? • Strong translational focus – many clinician scientists, focus on in vivo animal models, new drug development including first-in-human clinical trials, primary human samples • Track record - 68 publications in 2020: NEJM, Science, Cell Stem Cell • Onsite Platforms needed for haematology – genomics, flow, mouse, imaging • National registries – strong links with School of Public Health • Strong interactive environment - weekly joint lab sessions, shared resources & technologies
  63. 63. Head of Department Department of Neuroscience Professor Helmut Butzkueven
  64. 64. 65 Department of Neuroscience Overview • We have 23 research groups covering a wide range of neurological and related disciplines:  Epilepsy  Multiple sclerosis  Headache and pain  Neuroimaging • We have 76 projects available!  laboratory-based research and clinical neuroscience research • We have world class infrastructure  Purpose built laboratories  Animal neuro-behavioural testing rooms  Clinical registries and bio-databanks • We partner closely with the Alfred Brain program (Neurology, Neurosurgery, and Psychiatry) Established in early 2018, we are one of the largest academic departments in the Central Clinical School with over 250 staff, adjuncts and students  Stroke  Neurodegenerative diseases  Neurocognitive and neuropsychiatric disorders  Neurotrauma  Small animal and clinical imaging  Fluid biomarker analysis equipment
  65. 65. 66 Why us? • The Brain is one of the most interesting and challenging organ of the human body  Brain disorders are very common, and often devastating  This makes our work highly rewarding • Neuroscience is highly collaborative  We are always looking to link basic and human neuroscience • Our strength are very close links between laboratory and human research  Our unique position at the Alfred Hospital allows us to undertake relevant and impactful research with patients to provide better care • We value the contribution of all of department members, in particular our students, and provide excellent mentorship Website - monash.edu/medicine/ccs/neuroscience/home Email - ccs.neuroscience@monash.edu Twitter - @MonashNeurosci
  66. 66. Laboratory Head – Baker Heart and Diabetes Institute Co-chair Research Training and Education Committee Associate Professor Brian Drew
  67. 67. 68 Honours and Graduate Research at Alfred Research Alliance We are at the fore front of discovery research, human research studies and epidemiological studies related to cardiovascular, metabolic diseases and diabetes. Why do research at Baker Institute? • Internationally recognised researchers as accredited supervisors • State of the art analysis and imaging facilities • Multiple platform technologies and research cores • Strong academic and industry collaborations • Several funding opportunities scholarship top-ups, professional development • Student body of ~65 students each year (great support network) • Active student committee (many professional and social opportunities)
  68. 68. 69 Honours and Graduate Research at Alfred Research Alliance Key areas of Hons and PhD projects For more information baker.edu.au/students or study@baker.edu.au Imaging Biomarkers Discovery science Cell Signalling
  69. 69. Deputy Director, Burnet Institute Professor James Beeson
  70. 70. Burnet Institute
  71. 71. Head, Department of Diabetes Professor Mark Cooper
  72. 72. Department of Diabetes
  73. 73. Head Department of Immunology and Pathology Professor David Tarlinton
  74. 74. • Immunology is the study, manipulation and exploitation of the immune system. • The immune system is a complex, efficient and flexible network of multiple, highly specialised cell types that operate in virtually every part of the body to establish and then maintain homeostasis. • The immune system identifies perturbations in tissues, classifies the risk as sever or benign, organises an escalating response in proportion to the challenge and then remembers what it has done (vaccines). •The response is sometimes inappropriate, inadequate, overzealous or becomes exhausted – circumstances that may cause or permit disease. • Immunology is revolutionising the diagnosis and treatment of cancer, autoimmunity, asthma, allergy, infection, inflammation, and transplantation. The Department of Immunology and Pathology
  75. 75. Allergy/Asthma Antibodies Inflammation Mucosal Immunology Host-Microbe interactions Transplantation Research in The Department of Immunology and Pathology Human Immunity & immunodeficiency Respiratory Immunology O’Hehir Van Zelm Marsland Harris Hibbs Starkey Tarlinton Holland Smallwood Signaling Autoimmunity Organ development, regeneration & repair Autoimmunity Respiratory Research at The Alfred Chronic infections Google “Monash Immunology Research”
  76. 76. Group Leader, Department of Infectious Diseases Assoc Professor Joseph Doyle
  77. 77. Department of Infectious Diseases
  78. 78. Head, Department of Psychiatry Professor Jayashri Kulkarni
  79. 79. Monash Alfred Psychiatry research centre 2022 Project Topics Trauma and psychopathology • Borderline personality disorder (cPTSD) symptomatology, emotion regulation, and trauma history • How childhood trauma impacts adult cognition and emotion regulation Hormones and the mind • Mood, cognition and behaviour across the menstrual cycle: healthy women, PMS/ PMDD, chronic physical illness Menopause and depression • Early life trauma, stress sensitivity, and perimenopausal depression Body Image and Related Disorders • Effects of media/ sociocultural factors on body image related disorders Addiction • Women and Alcohol use: Experiences of care; healthcare professionals perceptions, attitudes and knowledge • Education in Addiction: Mapping healthcare undergraduate students’ education and training in addiction Stress and trauma HPA axis Sex hormones HPG axis
  80. 80. Epworth Centre for Innovation in Mental Health 2022 Project Topics Neural excitation / inhibition and mental illness • Electroencephalography • Biomarker prediction of mental illness Detection of peak brain wave frequencies for use in brain stimulation • Electroencephalography • Individualised brain stimulation Developing novel therapeutics for Cognitive Disorders • Using neurobiological data to investigate novel therapeutic targets • Electroencephalography • Neural excitation/Inhibition balance, cortical oscillations and connectivity • Alzheimer's disease, Mild Cognitive Impairment, Traumatic Brain Injury
  81. 81. Head, HIV/STI economics and Health Preference Research Melbourne Sexual Health Centre Jason.Ong@monash.edu Assoc Professor Jason Ong
  82. 82.  What we do – 50,000 consultations/yr – 100 staff – Lots of research  120 papers a year  What you’ll get – A project with existing data – Existing ethics – A 1st author publication  Subject to your contribution – Great supervision  Daily access  Please call any of the students on the next slide (or others) and ask them about us Melbourne Sexual Health Centre
  83. 83. Examples of the students and their outputs Tran Huynh Huynh T, et al. Global estimates for the lifetime cost of managing HIV: a systematic review. AIDS. 2021 doi: 10.1097 Evelyn Turek Turek EM, et al. Are genital examinations necessary for STI screening for female sex workers: A retrospective study of decriminalized and regulated sex workers in Melbourne. PLOS ONE. 2020; 15(4): e0231547. doi: 10.1371/journal.pone.0231547 Duygu Chloe Durukan Durukan DC, et al. Increasing proportion of herpes simplex virus type 1 among women and men diagnosed with first episode anogenital herpes: a retrospective observational study over 14 years in Melbourne, Australia. Sexually Transmitted Infections. 2019; 95(4):307-313 doi: 10.1136/sextrans-2018-053830 David Priest (4 papers) Priest D, et al. Neisseria gonorrhoeae DNA bacterial load in men with symptomatic and asymptomatic gonococcal urethritis. Sexually Transmitted Infections. 2017; 93(7): 478-481 doi: 10.1136/sextrans- 2016-052950 Melbourne Sexual Health Centre
  84. 84. General & Endocrine Surgeon Department of Surgery, Central Clinical School Assoc Professor James Lee
  85. 85. 86 Honours and Graduate Research at Alfred Research Alliance Department of Surgery We do clinical & translational research in a broad range of surgical disciplines. General Surgery Oesophagogastric & Bariatric Hepatopancreatic & Biliary Colorectal Breast Endocrine Surgery Cardiothoracic Orthopaedic Plastics & Reconstructive Burns Vascular Neurosurgery Otolaryngology, Head & Neck Urology
  86. 86. 87 Honours and Graduate Research at Alfred Research Alliance For more info email : James.Lee@monash.edu THYROID CANCER RESEARCH OPPORTUNITIES & PROJECTS Clinical Research Machine Learning Patient Reported Outcomes Translational Research Monash University Endocrine Surgery Database Postdoctoral Scientist Dpt Data Science & Artificial Intelligence ANZ Thyroid Cancer Registry PMCC Monash Health Molecular Genetics Hudson
  87. 87. Head of Department Gastroenterology Prof Alex Boussioutas
  88. 88. 89 Gastroenterology honours and graduate research projects Department of Gastroenterology – Gastroenterologists, nurses, pharmacists, scientists, nutritionists, psychologists Hepatology NAFLD/MAFLD/NASH Hepatoma Chronic Liver Disease Viral Hepatitis GI Cancer Progression of gastric cancer Genetics of Inherited GI cancers Immunophenotype of cancer Molecular biomarkers of premalignant gastric lesions Functional GI Disorders FODMAP, diet and disease Neuromodulation in gut Inflammatory Bowel Disease Drug therapy of IBD Nutrition and Crohn’s Disease Optimizing treatment IBD Endoscopy Screening for cancer
  89. 89. 90 Gastroenterology honours and graduate research projects Some papers we have published
  90. 90. Professor/Director, Department Renal Medicine Professor Paul Lawton
  91. 91. 92 Honours and Graduate Research at Alfred Research Alliance Alfred Dept of Renal Medicine >100 staff 8 Renal physicians ~200 facility haemodialysis patients, ~100 home dialysis patients ~30 kidney transplants each year + dual organ transplants Specialised nephrology: AKI/MGRS/HIV/ CKD post-transplant Central Clinical School: - Epidemiology - Health Services Research - Mixed methods
  92. 92. 93 Honours and Graduate Research at Alfred Research Alliance “Towards equity of access & equity of outcomes” - transplantation - treatment closer to home - hospital care For more info email paul.lawton@alfred.org.au
  93. 93. Professor of Oncology Group Leader, Cancer Development and Treatment Laboratory, Department of Medicine, Central Clinical School Professor Mark Shackleton
  94. 94. 95 Honours and Graduate Research at Alfred Research Alliance The Cancer Development and Treatment Group comprises research staff, post- doctoral fellows, PhD students and BSc Honors candidates and undergraduates. We undertake research into the development, progression and treatment of solid cancers, which collectively make up >80% of all cancers Our main disease of interest is melanoma, but we also study other cancers The techniques we use are wide-ranging - cell biology, molecular biology, omics, computational biology Our main research areas of interest are: EZH2 IP-Mass Spec scRNAseq NIRSC flow cytometry Cancer Heterogeneity Epigenetics Stem Cell Biology
  95. 95. 96 Honours and Graduate Research at Alfred Research Alliance Main Research Themes: • Building better, integrated models of cancer immunology that consider: • immune functionality • tumour/immune genomics • microbiota • environmental factors • Biomarker and liquid biopsy analysis • Methods to reduce immunotherapy- related toxicity Research opportunities/projects: 1. tracking immune cell population changes against outcomes of immune checkpoint blockade 2. biomarkers to predict immunotherapy toxicity 3. can sex hormones affect response to molecular targeted therapy in cancer? For more info email miles.andrews@monash.edu (NHMRC Early Career Fellow) c a b Figure 2. d 100 Tumor bearing Tumor free Response NR R -4 -3 -2 -1 0 1 2 3 4 Bacteroides stercoris ATCC 43183 Parabacteroides distasonis Anaerocolumna jejuensis Alistipes unclassified Fournierella Fournierella massiliensis Ruminococcus unclassified Citrobacter unclassified Enterobacter unclassified Hafnia unclassified Klebsiella unclassified Enterobacter Hafnia Hafniaceae Weissella paramesenteroides Eubacterium hallii Roseburia hominis Lactobacillus rogosae Bacilli Lactobacillales Klebsiella LDA score (log10 ) -20 -15 -10 -5 0 -15 -10 -5 0 log 2 (relative abundance) log 2 (relative abundance) 0.50 ined) p=0.436; R2= 0.0165 Cancer & the microbiome Integrating genomic, immune, environmental data
  96. 96. Department of Medicine, Peninsula Clinical School Professor Velandai Srikanth
  97. 97. 98 Peninsula Clinical School – Research Opportunities Medicine Surgery Epidemiology Bibliometric research
  98. 98. 99 Peninsula Clinical School – Research Opportunities Colchicine for coronary inflammation Prof. Jamie Layland jamie.layland@monash.edu jlayland@phcn.vic.gov.au Measuring phone-based physical activity for trials A/Prof. Richard Beare richard.beare@monash.edu Quality of GP care after stroke Prof. Nadine Andrew nadine.andrew@monash.edu 3D printing and imaging in reconstructive surgery Prof. David Hunter-Smith david.hunter-smith@monash.edu Fitness, physical activity and brain health at mid-life in a childhood cohort A/Prof Michele Callisaya michele.callisaya@monash.edu Bibliometric analysis • What is healthy ageing? • Mapping Australian COVID research Dr. Taya Collyer taya.collyer@monash.edu
  99. 99. Professor of Physiotherapy Head, Respiratory Research @ Alfred Professor Anne Holland
  100. 100. 101 Honours and Graduate Research at Alfred Research Alliance Respiratory Research @ Alfred Research expertise in advanced lung diseases including asthma, COPD, pulmonary fibrosis, lung cancer, pulmonary hypertension, cystic fibrosis, and lung transplantation Spans laboratory-based research, clinical research, clinical trials, epidemiology and registry-based studies, qualitative research and implementation of research into practice. e.g. Images
  101. 101. 102 Honours and Graduate Research at Alfred Research Alliance Key opportunities for honours projects 1. Non-drug treatments for people with chronic lung disease – oxygen, high flow, singing, rehabilitation 2. Attitudes to ongoing public health measures (e.g. mask wearing) amongst people with chronic lung disease 3. Psychosocial effects of COVID-19 pandemic on frontline health workers 4. Implementation of screening for lung cancer 5. Improving quality of care through the Victorian Lung Cancer Registry Lab heads Respiratory Care Prof Anne Holland Chronic Respiratory Disease A/Prof Natasha Smallwood Lung Cancer A/Prof Rob Stirling For more info go to https://www.monash.edu/medicine/ccs/aPrmed/home or email anne.holland@monash.edu
  102. 102. MONASH CENTRAL CLINICAL SCHOOL MONASH SCHOOL OF PUBLIC HEALTH & PREVENTIVE MEDICINE Honours and Graduate Research at Alfred Research Alliance Thank you for attending! Let’s continue the discussion at the Departmental Q&A Zoom Sessions @ 7:30PM
  103. 103. Reminders  This webinar will close at 7:30 – Please copy Q&A links from the chat if needed – Please wait until 7:30 to log into departmental Q&A session  Honours application: Open 16th August – 12th November  Please fill in our survey  Any further questions please email – CCS : ccs.honours@monash.edu – SPHPM: med-sphpm-honours@monash.edu
  104. 104. Special thanks to …  Professor Stephen Jane, Dean, Sub-Faculty Public Health and Translational Medicine  Professor Terence O’Brien, Head of CCS and Professor Sophie Zoungas, Head of SPHPM  All our speakers  Moderators - Professor Robyn Slattery, Dr Vilija Jokubaitis, Ms Sharon Gurry  Honours coordinators  Research managers and all supporting staff Acknowledgments

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