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2020 Alfred Research Alliance Honours and graduate research information night

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2020 Alfred Research Alliance Honours and graduate research information night

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The Alfred Research Alliance partners, Monash University's Central Clinical School and School of Public Health and Preventive Medicine, and the major research institutes of Burnet and Baker, hosted an information evening on 11 August for people interested in undertaking Honours and graduate research study in 2021 at the Alfred Research Alliance site in Melbourne, Australia.

The Alfred Research Alliance partners, Monash University's Central Clinical School and School of Public Health and Preventive Medicine, and the major research institutes of Burnet and Baker, hosted an information evening on 11 August for people interested in undertaking Honours and graduate research study in 2021 at the Alfred Research Alliance site in Melbourne, Australia.

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2020 Alfred Research Alliance Honours and graduate research information night

  1. 1. MONASH CENTRAL CLINICAL SCHOOL MONASH SCHOOL OF PUBLIC HEALTH & PREVENTIVE MEDICINE Honours and Graduate Research at Alfred Research Alliance Tuesday 11th August 2020 Information Evening CCS, SPHPM, Baker, Burnet
  2. 2. Dean, Sub-Faculty Public Health and Translational Medicine, Monash University Director of Research, The Alfred Professor Stephen Jane
  3. 3. Public Health & Translational Medicine – where your research matters biomarkers drug discovery devices clinical trials clinical registries population studies occupational & environmental health health economics basic science translational research
  4. 4. Central Clinical School School of Public Health and Preventive Medicine Who are we?
  5. 5. Honours coordinators: A/Prof Christoph Hagemeyer(CCS) A/Prof Margaret Hibbs (CCS) Dr Vilija Jokubaitis (CCS) Prof Danny Liew (SPHPM) A/Prof Joanne Ryan (SPHPM)Dr Darshini Ayton (SPHPM) Who should you talk to?
  6. 6. Alfred Surrounds
  7. 7. Clayton Surrounds
  8. 8. • an awesome experience! • immersion in world-class research • opportunity to make a difference • training and mentoring by world-class researchers What will you gain?
  9. 9. What does ‘translational research’ mean? Why do it? Translational Research
  10. 10. • Alfred Research Alliance Scholarships x 2 ($6000) • www.monash.edu.au/study/scholarships/honours/ Scholarships
  11. 11. HOPE TO SEE YOU NEXT YEAR MONASH CENTRAL CLINICAL SCHOOL MONASH SCHOOL OF PUBLIC HEALTH & PREVENTIVE MEDICINE
  12. 12. Event Co-Host Ms.Lakshanie Wickramasinghe
  13. 13.  Zoom Webinar 6:00PM – 7:30PM  Use the Q&A Function on bottom of screen to ask questions about any presentations you have seen.  Assigned moderators will answer your Qs – Dr. Vilija Jokubaitis (Honours Coordinator) – Dr. Joanne Mouser (CCS student services) – Ms. Sharon Gurry (SPHPM student services)  Send email to ccs.honours@monash.edu or med-sphpm-honours@monash.edu Event Housekeeping - Webinar
  14. 14.  Departmental Q&A Zoom Meetings 7:30PM – 8:30PM – Ask verbal questions and also type your questions – Panel of enthusiastic academics in each of department  Hope you enjoy the diverse research that will be shared tonight and it inspires you to come and join us as this great research precinct. Event Housekeeping: Departmental Q&A Zoom Meetings
  15. 15. Head, Central Clinical School Program Director, Alfred Brain Prof. Terence O’Brien
  16. 16. biomarkers drug discovery devices clinical trials clinical registries outcomes research population studies occupational & environmental health health services research health economics Mechanisms of disease Imaging CCS SPHPM CCS: Translational Research
  17. 17. Neuroscience Musculoskeletal Diabetes Cardiology Haematology Infectious Diseases Trauma Mental Health Sexual Health Anaesthesia Immunology Respiratory Allergy Gastroenterology Women’s HealthAgeing Critical Care Imaging Surgery CCS: What Diseases Do We Research?
  18. 18. Department/Centre & HOD Head of School Terry O’Brien ACBD/Haematology Harshal Nandurkar Anaesthesiology & PM Paul Myles Diabetes Mark Cooper Gastroenterology Peter Gibson Immunology & Path. David Tarlinton Infectious Diseases Anton Peleg Psychiatry Jayashri Kulkarni MSHC Kit Fairley Medicine - Alfred Terry O’Brien Medicine - Peninsula Velandai Srikanth Oncology Mark Shackleton Neuroscience Helmut Butzkueven NTRI Mark Fitzgerald RACI Robyn O’Hehir Surgery & CORE Wendy Brown Med Education Anne Powell Education (non Med) Robyn Slattery Psychiatry Anaesthesiology & Perioperative Medicine CCS: School structure
  19. 19. •An awesome experience! •Immersion in world-class medical research environment •Embedded in specialist clinical hospital •Training and mentoring by world-class clinical & translational researchers – >30 NHMRC Investigator Grant Holders What will you get?
  20. 20. •Formal training in research methods •Publications What will you get?
  21. 21. Honours coordinators: Who should you talk to? Speak to potential supervisors: Webpage: https://www.monash.edu/medicine/ccs/education/future- students/honours Link to CCS project booklet: https://www.monash.edu/__data/assets/pdf_file/0003/2210556/2021- CCs-Honours-and-postgrad-research-project-booklet.pdf CCS Honours Student Services: E: ccs.honours@monash.edu A/Prof Christoph Hagemeyer(CCS) A/Prof Margaret Hibbs (CCS) Dr Vilija Jokubaitis (CCS)
  22. 22. MONASH MEDICINE, NURSING & HEALTH SCIENCES Director, Teaching and Learning Head, Medical Education Research and Quality (MERQ) unit School of Public Health and Preventive Medicine Prof. Dragan Ilic
  23. 23.  BMedSci  BBiomed  BHealthSciences – 553 St Kilda Rd – MMC – VIFM  1,200 staff employed  $38 million average research income  783 average number of publications  #46 globally in preclinical and health sciences Honours at SPHPM
  24. 24.  ASPREE – Aspirin in the elderly, 14+ sub-studies (depression, cancer, genomics…)  Cancer – Registries, melanoma imaging and diagnosis  Clinical epidemiology – Infectious diseases, cardiovascular, musculoskeletal  Research methodology – Data sciences, analytics, Cochrane Opportunities across disciplines
  25. 25.  Health services – Registry science, transfusion/prostate/bariatric surgery…  Occupational and environmental health – Hazelwood health study  Critical care research – ANZIC-RC, pre-hospital/emergency/trauma research  Social sciences – Global and women’s health Opportunities across disciplines
  26. 26.  Metabolism, genomics and ageing – STAREE, diabetes and vascular medicine, ageing, public health genomics  Health professions education – Cost and value, pedagogical research  Monash Centre for Health Research and Implementation (MCHRI)  Department of Forensic Medicine Opportunities across disciplines
  27. 27. https://www.youtube.com/watch?v=i3f76uCJQs4&list=PL3C_ 6vEl3O5SzpzQ1Ca-zyF1oa7dEztc8&index=2 Careers in Public Health
  28. 28. The Honours Experience (CCS) Former Honours student Current PhD student Department of Immunology and Pathology Central Clinical School Ms. Alexandra Dvorscek
  29. 29. • Bachelor of Biomedical Science and Bachelor of Science – Majors: Immunology and Genetics and Molecular Biology – IMM3990- Jacobson laboratory (B cell and antibody memory) • 2019- Bachelor of Biomedical Science (Honours) – Tarlinton Laboratory (Immune Memory Laboratory) – Prof David Tarlinton & Dr Isaak Quast • 2020- PhD (translational research) – Immunology- Tarlinton Laboratory A little about me… Past Honours Experience
  30. 30. • Research project and coursework – Original research • Lab based, you will perform experiments and then present your data in a seminar and as a thesis • Whole new university experience • A lot of independence • Hard work but rewarding What is Honours? Past Honours Experience
  31. 31. • Meet with potential supervisors based on your interests/the projects offered • Ask about the lab work- make sure it’s something you could spend the year doing • Make sure you and your supervisor are on the same page – Hours, workload, communication, etc. • Speak to past/present students from that lab Choosing your project Past Honours Experience
  32. 32. • You will be left on your own – Your supervisor will help you learn all techniques you will use – Everyone around is really helpful and supportive • You’ll be expected to know everything – Not the case, you’ll be taught everything from square one – You’ll learn as you go (lab work/theory) • Honours takes over your life – If you’re organised, you can have a great work/life balance Misconceptions Past Honours Experience
  33. 33. Honours at ARA • Collaborative • Plenty of opportunities to learn about other topics (seminars, journal clubs) • Real lab experience • Great mix of staff and students • Opens up opportunities for the future • Great culture Past Honours Experience
  34. 34. Any further questions I’m happy for you to email me! Alexandra.Dvorscek@monash.edu Thank you! Past Honours Experience
  35. 35. The Honours Experience (SPHPM) Former Honours student Current PhD student Pre-hospital, Emergency and Trauma Research School of Public Health and Preventive Medicine Ms. Georgina Lau
  36. 36. • Bachelor of Biomedical Science • Honours -Patterns of personal responsibility for injury events • PhD -Alcohol and drug use in major trauma injury events Past Honours Experience A little about me…
  37. 37. • Year of research after your degree • Transition year from university to the workplace • An opportunity to see if you enjoy research Past Honours Experience What is Honours?
  38. 38. • Explore your options • Take the time to meet potential supervisors • Pick a topic that interests you Past Honours Experience Choosing your project
  39. 39. Honours is not: • A year of research you have to do alone • Just for people who want to do research Past Honours Experience Misconceptions
  40. 40. georgina.lau@monash.edu Past Honours Experience Contact
  41. 41. 3-MINUTE RESEARCH PRESENTATIONS MONASH CENTRAL CLINICAL SCHOOL MONASH SCHOOL OF PUBLIC HEALTH & PREVENTIVE MEDICINE
  42. 42. Group Head, Biological Neuropsychiatry and Dementia Research Unit School of Public Health and Preventive Medicine A/Prof. Joanne Ryan
  43. 43.  Australian & NZ College of Anaesthetists Clinical Trials Network  Australian & NZ Intensive Care Research Centre  Pre-hospital, Emergency and Trauma Research  Transfusion Research  Monash Clinical Registries (30+)  Cancer Research Program  Centre for Cardiovascular Research  Diabetes & Vascular Medicine  Infectious Disease Epidemiology  Primary Prevention Randomised Clinical Trials (ASPREE, STAREE)  Musculoskeletal Unit  Global & Women’s Health  Climate & Environment  Insurance, Work & Health  Monash Centre for Health Research & Implementation  Biostatistics & Modelling  Cochrane Australia School of Public Health (SPHPM): Improving the quality and safety of healthcare
  44. 44. ✔ Randomised controlled trial ✔ Community-based trials ✔ Prospective studies ✔ Observational methods ✔ Patient experiences ✔ Epidemiology ✔ Biostatistics ✔ Big Data ✔ Qualitative research ✔ Mixed-methods research ✔ Systematic reviews ✔ Health economics ✔ Implementation research ✔ Clinical Practice Guidelines ✔ Health Policy SPHPM: Methods Applied
  45. 45. STAREE Clinical Trial  Ground breaking community-based trial of the effects of statins on health outcomes in older individuals.  Recruiting >10,000 participants aged 70+ years across Australia  Collecting information on numerous health outcomes, lifestyle and quality of life.  Contribute to this exciting study and join our team of clinicians, study managers, field officers, data officers, post doctoral researchers and PhD students. For further details: andrea.curtis@monash.edu Prof. Sophia Zoungas A/Prof. Ingrid Hopper Dr. Andrea Curtis
  46. 46. ASPREE Clinical Trials: Promoting healthy ageing in older individuals The impact of social isolation and loneliness Dr. Rosanne Freak-Poli Dementia risk prediction and epigenetic biomarkers A/Prof. Joanne Ryan How physical activity can modify health outcomes Dr. Danijela Gasevic
  47. 47. Critical Care Research: Pre-hospital, emergency and trauma  Perioperative performance variation in cardiac surgery  Recover from traumatic injury  Imaging for pyelonephritis in the Emergency Department  Emergency hospital admission critical bleeding  Drug & alcohol use in non-traffic trauma deaths  Evaluating interventions to prevent serious road traffic crashes  Nutrition during critical illnesses Examples of honours projects :
  48. 48. Perioperative Medicine: Clinical trials in anaesthesia and perioperative medicine Improving outcomes for patients having major surgery Examples of recent honours projects:  Chewing gum to treat nausea & vomiting  Chronic subdural haematoma outcomes Prof. Kate Leslie AO
  49. 49. Clinical Registries (30+) National Gynae-Oncology Registry  ovarian cancer outcomes Burns Registry of Australia & New Zealand  burns injuries during school holidays  profile of young adult patents with burn injuries Victorian Cardiac Outcomes Registry  time-trends in outcomes following Percutaneous Coronary Intervention (PCI)  management & outcomes of patients with Acute Coronary Syndrome Australian Cystic Fibrosis Data Registry  Patient reported outcomes in CF patients For further details: cheryl.grant@monash.edu
  50. 50. Multi-disciplinary team of clinicians and allied health staff, primary care practitioners, not-for- profit organisations, patients & caregivers. Integrate patient-reported outcomes into clinical care to improve:  quality of life  symptom burden and unmet needs  survival For further details: liane.ioannou@monash.edu Dr. Liane Ioannou Prof. John Zalcberg 3D imaging technology for:  early diagnosis of melanoma  surveillance of high-risk individuals A/Prof. Victoria Mar Cancer Research
  51. 51.  Circulating microRNA as biomarkers for CVD  Genetic variants modifying CVD risk  Impact of folic acid supplementation on CVD  Health Economic Assessment A/Prof.Ilana Ackerman Prof. Danny Liew Basic, clinical & epidemiological research Cardiovascular Disease
  52. 52. Research into the causes and treatment of arthritis and back pain For further details: jointstudy@monash.edu  Effect of obesity & physical inactivity on joint health  Testing new treatments for arthritis and low back pain using specialized medical imaging techniques  Inter-relationship between joint health & CV  Optimising outcomes following joint replacement Musculoskeletal Unit
  53. 53. For further information: jane.fisher@monash.edu Recent honours projects: Intimate partner violence during pregnancy in Vanuatu Social-economic development & pregnancy mental health in rural Vietnam Attitudes of young Sri Lankans in Australia towards mental health and accessing mental healthcare Our research is conducted in Australia and the Indo-Pacific region We generate evidence to explain health inequalities, & translate research to promote health and improve health services Global and Women’s Health
  54. 54.  Polycystic ovary syndrome  Targeting maternal obesity  Health-related behaviours in postpartum women  Adult-onset Type 1 Diabetes: diagnosis experience & access to care Diabetes & Vascular Medicine Women’s & Children’s Health Implementation & Healthcare Improvement Research methodologies Platform Monash Centre for Health Research and Implementation
  55. 55.  Climate change, air pollution & environmental health  Links between air pollution and autism  Wind farms and human health  Do mobile phones affect cognitive development in children?  Firefighters’ Health Study  Asbestos cement workers Prof. Yuming Guo Climate and Environment: Monash Centre for Occupation and Environmental Health
  56. 56.  Relationship between medication use and functional recovery  Healthcare delivery & return to work trajectories  Quantify unique injury profile among educators  Geographic mapping of work disability in Australia  Impact of policy change and system shocks Dr. Shannon Gray Dr. Tyler Lane Insurance, Work and Health Group
  57. 57.  Estimation tuberculosis reactivation rates following exposure  Knowledge translation for stroke living guidelines  Interrupted time series studies in public health  Reproducibility & transparency in the synthesis of research findings  Medical Education Research & Quality (MERQ) unit Prof. Dragan Ilic Dr. Tari Turner Research Methodology: Biostatistics, Cochrane, Health Economics
  58. 58. Head, Australian Centre for Blood Diseases Prof. Harshal Nandurkar
  59. 59. Research Focus Myeloma Leukaemia Stem Cells Cancer and Immune Cell Signalling Thrombosis and Vascular Biology, Microfluidics and Theranostics Australian Centre for Blood Diseases Largest hospital-based translational research department in blood diseases
  60. 60. Key Strength at ACBD: Close interaction between lab and clinical service Several clinician-scientists have roles within lab-based research and in the hospital Facilitating ‘beside to bench’ translational research ACBD Major Research Funding past 5 years $51.6M from NHMRC, MRFF, ARC $12M from Clinical trials Australian Cancer Research Foundation funding for Blood Cancer Therapeutics Centre Australian Centre for Blood Diseases
  61. 61. Head, Department of Neuroscience Prof. Helmut Butzkueven
  62. 62. • Epilepsy – “understanding epileptogenesis and personalized treatment and everything in between • Traumatic Brain Injury “better outcomes” • Imaging the Brain from Mouse to Human • Neuro-ophthalmology “It’s snowing all the time” • Multiple Sclerosis including MS genomics “personalizing risk and benefit” • Autoimmune Encephalitis cohort studies ‘A rare but devastating disease” • Brain tumours and inflammation Some Departmental Projects and Themes
  63. 63. Group Head, Molecular Metabolism and Ageing Baker Institute Dr. Brian Drew
  64. 64. “ One of the key requirements of our research is that it is easily translatable and offers solutions to urgent health problems.” Professor Tom Marwick, Director Independent medical research Institute • 30 individual research groups • Preclinical Discovery, Clinical Research and Public Health • Offer research projects for Honours, Masters and PhD • Student body of ~65 students each year (great support network) • Active student committee (many professional and social opportunities) • Strong focus on research outcomes, presentation and publication Baker Institute
  65. 65. What does the Institute offer? • Internationally recognised researchers as accredited supervisors • State of the art analysis and imaging facilities • Multiple platform technologies and research cores • Strong academic and industry collaborations • Competitive top-ups for PhD scholarship holders • Several internal funding opportunities (conferences/mini- grants) Where do I find further information? • Our website baker.edu.au/research/ • Student projects baker.edu.au/research/students/student-projects • Email supervisors or study@baker.edu.au • Enrolment through Monash University Baker Institute
  66. 66. Deputy Director, Burnet Institute Prof. James Beeson
  67. 67. Health programs and objectives Broad areas of expertise (Disciplines) • Life Sciences • Public Health • International Development International Programs • Myanmar and Mekong region • Papua New Guinea and Pacific Burnet Institute
  68. 68. • Environment of excellence in biomedical, public health, and international research • Opportunities across a diverse range of health issues and research skills • Experience research that is translated into clinical practice and public health programs and policy, or new health products and tools • Strong culture of education and career development • Wide range of opportunities and supports for students Examples of past students at Burnet Liriye Kurtovic Alisa Pedrana Danielle Horyniak Jasper Cornish Katherine O’Flaherty …and many more Being a student at Burnet Institute
  69. 69. Head, Department of Diabetes Prof. Mark Cooper
  70. 70. The Department of Diabetes is the first – and only – university department in Australia solely dedicated to diabetes research and its complications including kidney disease, heart disease and blindness. COLLABORATION RESEARCH EDUCATION INNOVATION The Department of Diabetes
  71. 71. BIOCHEMISTRY MOLECULAR BIOLOGY IN VITRO MODELS ANIMAL MODELS CLINICAL TRIALS OBSERVATIONAL STUDIES SIGNALLING PATHWAYS PHARMACOLOGY CELLULAR PHYSIOLOGY This could be your degree!
  72. 72. Head, Department of Immunology and Pathology Prof. David Tarlinton
  73. 73. •Immunology is the study of the immune system. •The immune system is complex. This is a requirement for responding to its ever-changing endogenous and exogenous environments. •It functions as a body-wide surveillance system, constantly assessing the integrity of the body, maintaining or restoring homeostasis. •Immunology is the basis for new precision therapies of great effectiveness in cancer, autoimmunity, asthma, allergy, infection, inflammation, and transplantation. •If the immune system is not the question, it’s always the answer. The Department of Immunology and Pathology
  74. 74. Immune system Self Foreign Lymphoid Myeloid HSC Tolerance ImmunityDisease Mechanisms/Diagnostics/Therapeutics Allergy Immunity Infection Tissue Repair Mucosa Microbiome Transplantation
  75. 75. Group Leader, Department of Infectious Diseases A/Prof. Joseph Doyle
  76. 76. Alfred Dept of Infectious Diseases 120 staff 35 ID physicians Victorian HIV Service Infections in ICU Specialised ID Services - Viral Hep / Burns / CF / SSI Antimicrobial Stewardship Hospital in the Home Dedicated ICH Service Infection Prevention Hospital Epidemiology General Infectious Diseases Ambulatory ID Care Spleen Australia R E S E A R C H Diagnostic Microbiology Adult Immunisation Service Regional Infectious Diseases Service
  77. 77. HIV Viral Hepatitis Influenza AMR / Hospital- acquired Pathogens General ID and Microbiology Infections in ICH Clinical Trials Spleen Australia International Health and Travel Medicine Health Services Research Evidence Synthesis Surgical Site Infections Antimicrobial Pharmacology Infectious Diseases Genomics Machine Learning and ID Research Opportunities
  78. 78. Head, Department of Psychiatry Prof. Jayashri Kulkarni
  79. 79. • Trauma and psychopathology – Borderline personality disorder (cPTSD) symptomatology, emotion regulation, and trauma history – How childhood trauma impacts adult cognition and emotion regulation • Hormones and the mind – Mood, cognition and behaviour across the menstrual cycle – healthy women, PMS/ PMDD, chronic physical illness • Menopause and depression – Early life trauma, stress sensitivity, and perimenopausal depression • Schizophrenia – Early life trauma, cognition and schizophrenia Monash Alfred Psychiatry research centre 2021 Project Topics Body Image and Related Disorders Effects of media/ sociocultural factors on body image related disorders Addiction Women, Hormones, Alcohol and Mood (WhAM) What do Australians look like in crowdsourced addiction research?: using online platforms (Amazon Mechanical Turk) to characterise Australian samples screened for addictive disorders (gaming, gambling, food, alcohol, tobacco)
  80. 80. • Neural excitation / inhibition and mental illness – Electroencephalography – Biomarker prediction of mental illness • Mindfulness and the Attention Blink Phenomena – Mindfulness Meditation – Electroencephalography – Neural mechanisms of action • Mindfulness and awareness of errors – Mindfulness Meditation – Electroencephalography – Meta-analysis • Mindfulness and Mental Health in University Students – Mindfulness Meditation – Mental Health Interventions Epworth Centre for Innovation in Mental Health 2021 Project Topics
  81. 81. Head, Melbourne Sexual Health Centre Prof. Christopher Fairley
  82. 82.  What we do – 50,000 consultations/yr – 100 staff – Lots of research  120 papers a year  What you’ll get – A project with existing data – Existing ethics – A 1st author publication  Subject to your contribution – Great supervision  Daily access  Please call any of the students on the next slide (or others) and ask them about us Melbourne Sexual Health Centre
  83. 83. Examples of the students and their outputs Evelyn Turek Turek EM, et al. Are genital examinations necessary for STI screening for female sex workers: A retrospective study of decriminalized and regulated sex workers in Melbourne. PLOS ONE. 2020; 15(4): e0231547. doi: 10.1371/journal.pone.0231547 Duygu Chloe Durukan Durukan DC, et al. Increasing proportion of herpes simplex virus type 1 among women and men diagnosed with first episode anogenital herpes: a retrospective observational study over 14 years in Melbourne, Australia. Sexually Transmitted Infections. 2019; 95(4):307-313 doi: 10.1136/sextrans-2018-053830 Emile Jasek Jasek E, et al. Sexually transmitted Infections in Melbourne, Australia from 1918 to 2016: nearly a century of data. Communicable Diseases Intelligence. 2017; 41(3): E212-E222. David Priest (4 papers) Priest D, et al. Neisseria gonorrhoeae DNA bacterial load in men with symptomatic and asymptomatic gonococcal urethritis. Sexually Transmitted Infections. 2017; 93(7): 478-481 doi: 10.1136/sextrans-2016-052950 Melbourne Sexual Health Centre
  84. 84. MONASH CENTRAL CLINICAL SCHOOL MONASH SCHOOL OF PUBLIC HEALTH & PREVENTIVE MEDICINE Honours and Graduate Research at Alfred Research Alliance Thank you for attending! Let’s continue the discussion at the Departmental Q&A Zoom Sessions @7:30PM

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