淺談光電同調控制的觀點在材料開發與應用上可能帶來的改變

淺談光電同調控制（Coherent Control）的
觀點在材料開發與應用上可能帶來之改變
On Novel Materials Exploration and Applications
Possibly Brought by the Photonic Coherent Control Perspective
Speaker: Chungpin Liao (Hovering)
廖重賓（飛翔）
國立虎尾科技大學光電所
光電同調控制實驗室（Coherent Control Lab.）
cpliao@alum.mit.edu
2009/12/10 National Formosa University -cpliao 1

2009/12/10 National Formosa University -
cpliao
2
Outline
Coherent Control (同調控制) in the Wide Sense
Some Emerging New Topics & Thoughts
More Wild Topics to Scratch Our Heads Over

Coherent Control (同調控制) in the Wide Sense
Definition:
The use of coherent radiation, generated by various driving sources,
to change the behavior of atomic, molecular, or electronic systems,
often to alter the likelihood of a chemical reaction
Driving sources: 1. Wave 2. Particle 3. Dipole Engineering 4. Mind
Goals: 1. Permanent property modification
2. Dynamic performance change
Gene algorithm
Real-time probe
Brain

Some Emerging New Topics & Thoughts
• Electro-Optics is actually Electro and Optics separately
at present. (SPR)
• Magnetics remains an area of very low frequency,
far from light frequencies. (r)
• Conductivity remains quantity of relatively low frequency,
far from light frequencies. (passive elements, Weibel amplifier)
• New possibilities for optics emerge in the nanotechnology
era. (dipole engineering: FreqPush, AsymScat, newBrewster)
• Applications based on interactions between lights and
bio-systems / bio-materials are thriving. (Kirlian, SEA,
light-protein, LLLT, GdIONP magnetic fluid hyperthermia)
• High efficiency solar energy harvester is in mind.
(chl-a organic cell)

Electro-Optics is actually Electro and Optics separately at present. (SPR)
Fastest electronic gate: ~ 30 GHz in literature, ~ 10 GHz in industry
Visible light frequency: ~ 1015 Hz
10 GHz : 1015 Hz = 1 : 105  electronics never catches up with lights!
In a way, present day Electro-Optics or Photonics are mere “low-end”
products of what the real Electro-Optics combination should be.
There are much room left in the upper frequencies for electronics!

Currently, probably the only exception is the surface plasmon resonance
(SPR) in which a light frequency electro-optic complex is formed, even though
it is not a tangible optic device like a lens still.
Further, developing large-kx SPR would be needed.
(So far, only small kx is accessible by optical means.)
0
1
2
Surface Plasma Wave
p-wave
Prism
Metal
Sample

Magnetics remains an area of very low frequency, far from light frequencies. (r)
Recall that the index of refraction (n) of a material is:
     r r n  
We are only relatively good at measuring or even making materials represented
by the dielectric coefficient r which are responsive at light frequencies.
There are simply no light frequency magnets!

Conductivity remains quantity of relatively low frequency, far from
light frequencies. (passive elements, Weibel amplifier)
To achieve very high speed (or, at light frequencies) new electro-optic circuits,
we’d likely need conducting interconnects functioning at such speed.
For example, a future SPR circuits functioning
at light frequencies would need unique wave
filters, reflectors, phase changers, relays and
interconnectors.
Possible Weibel amplifier
for lights in the air – patent pending

New possibilities for optics emerge in the nanotechnology era
(dipole engineering: FreqPush, AsymScat, newBrewster)
All macroscopic optical phenomena (e.g., reflection, refraction, transmission,
diffraction) are the results of combining (interfering) numerous microscopic
quantum light scattering scenarios from dipoles.
In the eyes of light waves, all living and nonliving things are dipoles (including
induced and permanent).
-
+

The traditional Fresnel equations in the electromagnetic theory have been
used in determining the light power distribution at an interface joining
two different media in general.
When expressed in terms of dipoles, the right places (volumetric and
interfacial) to alter the light refraction behaviors become clear.

   
 


t
  


 










sin
i t i
t i

cos





  



t

sin
cos
a b
E  E  E  E  E 
E
i r t
|| || || || || ||
t S t

s
x





  
p
i
P M
E
  

 
 2cos sin
0
0
0
 
 










i t i
t i
p
r
P M
E
  

 
 2 cos sin
0
0
0
volumetric interfacial
 
   
S t  k r t 
M s s
 
 
cos
1
0
new Brewster angle asymmetric refraction

Dipole Engineering
Thus, manipulating nano or molecular dipoles (including adding different
types and numbers) can lead us to all new light behaviors,
as well as novel optical materials and devices.
It can be applied to achieve, e.g., emergence of a shifted resonance,
asymmetric refraction, new Brewster angle, etc.
Q: Technically how?
A: e.g., using light curing (光硬化) process and magnetized Fe3O4

transmission (red light)
intrinsic new
Multiple Brewster angles
Two Brewster angles due to
adding of magnetic particles
(0.2 micron dia.) (wt % =
0.057% ) in UV jell
electric dipole

E




t i
S cos

t
y M
i
n
0

n n
cos 
cos
i
t
t
t
0










i
due to distributed double layer
t
traditional

t

t
i
cos cos

i
i


cos cos

i
n n
i

n n

i
t
t
t

t
r
0


 

i p
p
E
E
r
0























S t
cos cos
 

x M t
E




t i
t
n
0

n n
cos 
cos
i
i
t
t
0










t
due to distributed double layer
i
traditional

t

t
t
cos cos

t
t


cos cos

t
n n
i

n n

i
i
i
i

i
r
0


 

i s
r
s
E
E
0
























Asymmetric
refraction
on PVDF,
where
[[E||]] no longer
vanishes

Applications based on interactions between lights and
bio-systems / bio-materials are thriving.
(Kirlian, SEA, light-protein induction, LLLT,
GdIONP magnetic fluid hyperthermia)
Kirlian Photography (靈光照相術)

• Kirlian photography has been mystical and controversial, and perhaps most
famous for its “phantom leaf” (幽靈葉子) phenomenon.
(a) Leaf intact (b) Trimmed leaf
(Courtesy of K. L. Johnson)
(Courtesy of Peter P. Gariaev, Tovmash Alexey)
and Ekaterina A. Leonova-Gariaeva

Comparison in 2D-spatial-FFT space:
正常挫敗感
癌症1 癌症2
自閉症
由轉換後之頻率域
圖可明顯發現其生
物生、心理狀態不
同，會呈現不同的
特徵，相較於空間
域而言，在空間域
不容易發現特徵。

6000
4000
2000
0
空氣
200 300 400 500 600 700 800
Wavelength(nm)
Counts
• Living and non-living subjects are
“Kirlian-wise” different.
• Not due to water molecules, since
coin gives out auro too.
• Not due to human-released
molecules, since all Kirlian
discharge are characterized by
the same “air spectrum”(UV).
• Living subjects seem to have their “fields”
(生物能場 coherent control source?)
interacting with the imposed discharging field
to give out variable Kirlian patterns.

Subtle energy analyzer (SEA) is used to probe microscopic current
flow in humans and in plants when subjected to lights.
Plant wound current (受傷電流) morphology measurement
via subtle energy analyzer (SEA) – being treated by photonic means
A1: (受傷前) (放大
後) (縱軸
0.02=>0.004)
A2: (受傷後) (放
大後) (縱軸
0.02=>0.004)

Low-level laser therapy 1 min
cpliao
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雙極肢電導(Lead
I~III)
胸電導(V1~V6)
增強單極肢電導(aVR、aVL、aVF)
治療前濾波訊號1 0~50
治療後濾波訊號1 0~50
LLLT-caused
accumulation

cpliao
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具頻譜顯示特徵之新心電圖儀(ECG)

cpliao
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意念控制指示與禪定訓練機

由神經傳導速率（NCV）可評估神經、肌肉之功能正常與否，
例如：由測膀胱括約肌之NCV可評量膀胱功能進步或退化情形
Active and passive
將量得的電流時序信號作傅立葉轉換（Fourier Transform）發掘出各種疼痛
的隱藏“模式“ （modes），可供辨認、評估真正的痛因，包含多種疼痛都
交迭出現、甚且互相影響的情形，或有referral pain的場合
 量子藥
cpliao
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肌電儀
疼痛頻譜儀（Pain spectral analyzer）
受傷／恢復電流量測& 光電調養
利用光電同調控制（由基因演算法導引低功率雷射等）改進電流時序信號
的波型或移動其頻譜上之“模式“位置來達到療病、增進健康的目的

Low-level laser therapy (LLLT)– 低功率雷射傷口癒合
糖尿病癒合不良之病患傷口
經過3 次雷射
照射(每次約
3分鐘)之後
灰指甲掉落之傷口
經過3 次雷射
照射(每次約
3分鐘)之後
老年人接受清創術後之傷口
經過6 次雷射
照射(每次約
5分鐘)之後

Magnetic fluid hyperthermia (MFH) using optical drives
MFH + microwave AC magnetic field have been used in cancer treatment.
We instead discovered that the coherent optical means is much more effective,
via using CASTEP simulations (1st -principle quantum mechanical code).
Fe3O4
GdIONP: Gd-doped iron oxide nano-particle

High efficiency solar energy harvester is in mind.
(chl-a organic cell)
In rivaling with the dye-sensitized photocell (染料敏化太陽能電池),
we are considering direct engineering on chlorophyll (葉綠素).
1 kW/m2
(100 mW/cm2)
According to DMol3 simulations (another 1st-principle quantum mechanical
Code), ~ 9 V is reached.

Accidental Result: Chlorophyll organic cell （沾濕即用之葉綠素有機電池）
實體測試
茶可樂果汁
只要是水溶液皆可啟動該有機電池!!!
準
備
前
沾
水
後

發光模組
每沾濕一次就可24小時發光長達3至4天之久！！
之後可再沾溼使用3次左右

因應潮濕環境而自動產生訊號之衣物

Organic painting electric skin treatment
(有機電池人體彩繪): 除眼黛、去脂、活化、、、
 can be by painting or in paper patterns for pasting
Beneath skin treatment Local spot treatment
+

More Wild Topics to Scratch Our Heads Over
Is light a particle or wave? What’s their difference in terms of applications?
The most accurate physics theory nowadays is quantum mechanics.
Within it, the most accurate one is QED (quantum electrodynamics).
In QED, light is particulate, and in unit of photon traveling at the light speed c.
The particle picture then reveals what a quantum scattering is and how
a light beam can slow down in a material, even a “photon” can only travel at c.
The wave picture may guide us in searching for how lights influence protein
generation and cell birth/death dynamics (e.g., through cytochrome-C, Bcl-2,
p53, etc.).
What’s that in a general material that can interact with lights?

A light beam can heat up a chunk of wood or a piece of metal. Can it be
solely explained from energy flux perspective? What about charge?
E
B
  
  
F il B B
So, an AC current arises
So, a force resulted to
do WORK
on the electron cloud
(the whole thing: a dipole)
The same mechanism works for insulators,
such as a piece of dry wood,
except that there the
electrons are NOT free to move around. (dipole)

Why can light slow down in media? What’s changed? Wavelength
or frequency? Why? Does it have to be so always?
dipoles
' s added
t 
c
A phase lag means
delay in arrival.
Under all circumstances, a photon can only travel at the light speed c.
However, there are intermittent disappearances (wherein new
photon-dipole complexes are formed) of a photon during its passage through
“a cluster of dipoles”– a material in general.
So, macroscopically (after the averaging), the lightwave is slowed down in
that material, with the phase velocity changed from c to v.
Q: Can robust new materials be created in this manner such that c  v  0 ?

Is the color sequence of a rainbow fixed? What has caused it so?
The rainbow pattern is the way it is because of the fact: n_red < n_orange
< n_yellow < n_green < n_blue < n_indigo < n_violet.
This is because the resonance is at UV. And, it can be changed.

If the resonance can be moved to the visible range…
For a glass thin-wall hollow prism filled with fuchsine (C20H19N3·HCl, 品紅)
and alcohol, light trespassing through experiences a resonance absorption
at green color, the refraction pattern becomes:
Blue
Indigo
Violet
dark
Red
Orange
Yellow
visible
R O Y G BIV UV
Q: Can you imagine the subsequent possible effects on humans and plants?

An electron is always anti-magnetic (diamagnetic), and every substance is
made of electrons, how come there are paramagnetic and even
ferromagnetic materials? What about situations at light frequencies?
An electron can certainly catch up with the light frequency since we
already see abundant light-responsive dielectrics resulting from
electronic responses to lights.
0H
electron
So, it must be related to the way
the atoms are stacked (or, latticed).
Entering the nanotech era, new morphology-modified high-frequency
magnetics are very possible.

If everything in this universe is a mere cluster of dipoles (electric and
magnetic) in the eyes of lights, why cannot we have new, revolutionary
optical materials and devices?
We certainly can. Especially, dipoles take all kind of forms.
So, there are abundantly many opportunities in front of us, spanning
from microwave to gamma ray frequencies!
Further, why cannot we manipulate lights in biological ways such that
they become favorable to human beings, creatures, plants, foods,
energy production, and environmental protection? (coherent control)
Gene algorithm
Real-time probe
Brain

Is there a light highway system within each human body or each plant?
According to Dr. Fei-Lun (費倫)’s discovery, there are at least two “liquid
crystals” (in the form of 膠原纖維(collagen fiber)) connecting two
adjacent cells within human body and these fibers overall might just
constitute a light highway system.
Ongoing numerical simulations (CASTEP, DMol3, OptiFDTD) and literature
indicate that IR lights in the range of 4 – 20 m, as well as UV lights of
200-300 nm, can almost freely pass through this light highway.
Is 灸in Chinese medication, simply to supply the needed IR spectrum?
In that sense, are Chinese meridians (經絡) related to this light highway?
Also, IR lights (in the form human body heat) may be a crucial ingredient
to trigger the generation of needed proteins in human body (see below).

If so, can light medicine (or, even quantum medicine) be realized?
In principle, yes, by sending correctly coded light pulse sequences or
light interference, or quantum waves into the human body along
the light highway.
Light pulse sequences should evolve (e.g., via gene algorithm) to adapt
to the best fighting positions to break the target bonding.
Correct light interference will sample the A, T, C, G distribution of the
promoter of a desired protein in an attempt to lead to the generation of
that specific protein.
Light or electric waves mimicking quantum wavefunctions may be
implemented to make up a missed pattern under the guidance of an MRA
(magnetic resonance analyzer, 共鳴磁場分析器)

Light message on the level of DNA (or RNA):
Light Capsule (光膠囊)  光彈  給予適切的光訊息– patent pending
By utilizing the theory of protein induction through instructive messages
embedded in light interference (光干涉)
Q: As a side remark, are all complexities within human body regulated by
simply 2% of DNA, while the rest 98% are merely junks?

The importance of sun lights to all life forms on earth is not just as energy
sources, but more subtly as information field.
Theory:
Nucleotides (A, T, G, C) activation probability distribution
established by light interference absorption spectra
= Population probability density distribution of nucleotides
in a promoter
The absorption spectra of all four nucleotides
in the wavelength range of 220nm~300nm
E.g., for 3-wave interference:
3 3
 
   
   
   
a
P f f
     
   
A A i T i
i i
 
1 1
3 2
 
f f
        
A i j  T i j

 i , j i ,
j

 
f f
             
A i j k  T i j k

 i , j , k i ,
j

b
9 2
c
27 2
similarly for PT, PC, PG, before normalization
f

Almost all known population distributions of light-sensitive promoters can be
reconstructed by light interference absorption distribution.
T
(a)
T
(b)
A
A
G
G
C
C
A T G C
(c)
Assumption: absorption  activation
Use artificial lights
E.g.:
(a) G-BOX nucleotides population
probability distribution
(b) Nucleotides excitation distribution
constructed from absorption of
light interference
(231nm, 496nm and 720nm)
(c) Nucleotides excitation distribution
from absorption of light interference
(239nm, 333nm and 701nm)

Protein induction: - activating protein promoters (啟動子)
through light interference action
E.g., 針對參與乳酸化過程的乳酸菌基因
Background:
乳酸化過程是由乳酸菌所產生的許多蛋白激酶所共同作用而完成，
乳酸（Lactate）是其中的一種生成物，如果特定的光線可以使得乳酸增加
而導致溶液中的pH值下降，那麼該光線可能活化了某些蛋白激酶，
使得乳酸的濃度上升。
乳酸化過程:
乳酸（Lactate）主要是丙酮酸（Pyruvate）被乳酸脫氫酶轉化而產生，
而丙酮酸是在糖酵解的過程中，由磷酸烯醇式丙酮酸產生。

在丙酮酸激酶的作用下磷酸烯醇式丙酮酸會生成ATP和丙酮酸。
每mole葡萄糖在此過程中為細胞提供2 mol 丙酮酸。
當丙酮酸被大量的轉化成乳酸時會使得pH值下降，溶液呈現酸性。

乳酸化所需的基因:
乳酸菌是利用半乳糖相關基因（galactose ）和合成乳酸脫氫酶
來進行乳酸的生成，例如LacT、GalK、CcpA
和LDH(乳酸脫氫酶, Lactate dehydrogenase)。
這些基因的promoters都具有一段稱為-35區域的序列，其型式通常為
AAAGGA、TTGCAT、TTTTGG、TTAAGC，
以base pair的出現頻率作統計, 結果為(見圖)：
有趣的是，
光線這個環境因子
並沒有在乳酸菌的
基因調控研究中被提及
A:33.33%, T:33.33%, G:16.67%, C:16.67%
Population probability density distribution

Our “Light Capsule” Approach:
Use light interference-rendered new photons (by virtue of bio
nonlinearity) to statistically sample the “Population probability density
distribution”.
Theory: Promoters are activated by sampling, NOT by precise determinism.
A:33.33%, T:33.33%, G:16.67%, C:16.67% A:18.53%, T:32.14%, G:26.02%, C:23.31%
Our first attempt….

A:31.79%, T:30.16%, G:19.81%, C:18.24%
Better attempt in theory
A:33.33%, T:33.33%, G:16.67%, C:16.67%

Yogurt (優酪乳) experiment: (乳酸菌數已飽和)
IR laser Green laser Reference (light) Reference (dark)
UV light tube (252 nm)

No laser driving …
6月9日A實驗組(未開雷射) A與B的差值(B/A-1) B對照組(亮) B與C的差值(B/C-1) C對照組(暗)
時間pH T (℃) pH T (℃) pH T (℃) pH T (℃) pH T (℃)
20:00 4.245 20.8 -0.05% 2.40% 4.243 21.3 -0.02% -3.18% 4.244 22
23:00 4.19 23.9 0.53% -0.42% 4.212 23.8 0.02% -0.83% 4.211 24
00:00 4.221 23.7 0.00% -0.84% 4.221 23.5 0.19% -2.08% 4.213 24
09:00 4.17 23.6 -0.05% -0.42% 4.168 23.5 -0.24% -1.26% 4.178 23.8
11:00 4.17 23.7 0.05% 0.00% 4.172 23.7 0.02% -1.25% 4.171 24
13:00 4.16 23.6 0.14% 0.00% 4.166 23.6 -0.02% -1.26% 4.167 23.9
15:00 4.157 24.1 0.12% 0.00% 4.162 24.1 0.00% -1.23% 4.162 24.4
17:00 4.159 24.5 -0.10% -0.82% 4.155 24.3 -0.07% -1.22% 4.158 24.6
20:00 4.152 24 -0.10% -0.83% 4.148 23.8 -0.10% -1.65% 4.152 24.2
22:00 4.15 24.3 -0.02% -0.41% 4.149 24.2 -0.02% -0.82% 4.15 24.4
Background radiation

6月3日A實驗組A與B的差值(B/A-1) B對照組(亮) B與C的差值(B/C-1) C對照組(暗)
時間pH ℃ pH ℃ pH ℃ pH ℃ pH ℃
20:30 4.22 18.6 0.26% 4.30% 4.231 19.4 0.26% -3.48% 4.22 20.1
20:40 4.249 20.1 -0.64% 3.98% 4.222 20.9 -0.38% -4.13% 4.238 21.8
21:00 4.235 21.8 -0.71% -0.92% 4.205 21.6 -0.36% -1.37% 4.22 21.9
21:10 4.208 21.9 -0.14% 1.83% 4.202 22.3 -0.12% 0.00% 4.207 22.3
10:30 4.199 24 -0.29% -5.42% 4.187 22.7 -0.21% -2.16% 4.196 23.2
11:30 4.199 24.2 -0.38% -7.85% 4.183 22.3 -0.17% -3.46% 4.19 23.1
06:30 4.171 23 0.29% -4.78% 4.183 21.9 -0.07% -2.67% 4.186 22.5
08:20 4.163 26.5 0.10% -1.89% 4.167 26 -0.07% 0.39% 4.17 25.9
10:30 4.148 25.1 0.27% -5.58% 4.159 23.7 0.12% -2.07% 4.154 24.2
12:30 4.138 24.7 0.31% -5.67% 4.151 23.3 -0.02% -2.51% 4.152 23.9

6月8日A實驗組A與B的差值(B/A-
1)
B對照組(亮) B與C的差值(B/C-1) C對照組(暗)
時間pH ℃ pH ℃ pH ℃ pH ℃ pH ℃
11:15 4.201 22.1 0.48% 1.36% 4.221 22.4 0.50% -3.03% 4.2 23.1
12:45 4.201 24.3 0.10% -0.41% 4.205 24.2 0.07% 0.00% 4.202 24.2
07:00 4.175 23.4 0.46% -0.43% 4.194 23.3 0.17% -1.69% 4.187 23.7
09:00 4.179 24.2 0.38% -2.07% 4.195 23.7 0.38% -2.47% 4.179 24.3
11:00 4.174 25 0.05% 0.40% 4.176 25.1 0.12% 0.40% 4.171 25
13:00 4.155 24.8 0.29% -2.02% 4.167 24.3 0.14% -1.22% 4.161 24.6
15:00 4.146 24.6 0.36% -1.22% 4.161 24.3 0.00% -1.22% 4.161 24.6
17:00 4.139 24.7 0.51% -2.02% 4.16 24.2 -0.02% -0.82% 4.161 24.4
19:00 4.146 24.5 0.46% -1.63% 4.165 24.1 0.05% -0.82% 4.163 24.3

In summary,
從乳酸菌基因的誘導轉錄中，可以發現若干典型的基因調控可能性，
但有趣的是，光線這個環境因子並沒有在乳酸菌的基因研究中被提及。
在優酪乳的pH值量測實驗中，pH值會因為紫外光＋可見光＋紅外光的照射
而降低，但目前還不能確定是否是因為乳酸脫氫酶的增加而導致乳酸的
濃度上升，或是有其它的未知原因存在。
為了確定這個部份，丙酮酸和乳酸脫氫酶定性和定量的檢測方法是
必需的(進行中)。
As such, is it possible that light messages can be employed in treating
many diseases, fighting viruses, adjusting bio-clock, and
even recovering of organs?
If so, a paradigm shift may emerge owing to the need for faster time-to-market.

If there is indeed light highway on a plant, is this why it can react to
human touch immediately even though it possesses no nerve system?
We highly speculate that there is such light highway within or on each plant
and the come-close of a human finger simply injects IR lights into
this light highway.
Again, IR lights (in the form human body heat) may be a crucial ingredient
to trigger the generation of needed proteins in the plant.

The vast knowledge of organic chemistry is largely a know-how under
room temperature and heat (i.e., a Maxwellian distribution of
particle velocities), not one under specifically tailored light spectra.
Q: Would a strange new world result if the latter is pursued?
Excitingly, yes. Under non-Maxwellian situation
(i.e., no longer the notion: temperature),
the organic chemistry likely will be very much different in content.
What if active coherent control is further involved?
Many new materials, functions, and applications, even those unimaginable,
will come out.
The expanding frontier can only be limited by men’s own imagination.

Coherent Control on the Level of Subatomic Particles:
PhotoGravitoBiology (光重力生物學)  just starting …
• Death field versus Bliss field
• EM origin of gravity
• Engineering on embedded
EM structure within local
gravity scalar potential
 manipulation on atomic nuclei,
molecules, large system (living &
nonliving), hence affecting:
health, agriculture, climate,
disease (e.g., SARS),
social stability (thought
& behavior), earthquake, etc.

淺談光電同調控制的觀點在材料開發與應用上可能帶來的改變

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