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Begoña Benito VillabrigaDAPA TrialDAPA Trial
Begoña Benito VillabrigaDAPA Trial
Background
MADIT II IRIS
Begoña Benito VillabrigaDAPA Trial
Background
Begoña Benito VillabrigaDAPA Trial
Background
Begoña Benito VillabrigaDAPA Trial
Objective
Begoña Benito VillabrigaDAPA Trial
Study design
Inclusion criteria:
Begoña Benito VillabrigaDAPA Trial
Results
Begoña Benito VillabrigaDAPA Trial
Results: patient characteristics
Begoña Benito VillabrigaDAPA Trial
Results: ICD implant and study groups
 Cross-over
Begoña Benito VillabrigaDAPA Trial
Results: primary end-point
Begoña Benito VillabrigaDAPA Trial
Results: secondary end-points
Begoña Benito VillabrigaDAPA Trial
Results
Begoña Benito VillabrigaDAPA Trial
Limitations
 Premature termination in 2013 (38% of patients), underpowered to
answer the hypotheses: interpretation of results?
 First inclusion in 2004: dramatic improvement in MI and HF
management
Begoña Benito VillabrigaDAPA Trial
Conclusions

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DAPA Trial