1. Using a new experimental test structure, biophysicists at JILA have unraveled part of a 15-year mystery in the mechanics of DNA. And Neutron scattering has been used to investigate the structure of fiber DNA during the melting transition. Carlos Andrés Galeano Baquero Medicine Student UPB School of health sciences
4. INTRODUCTION The Replication of DNA is a very important process today beacuse this offers clues about of the cancer disease an others genetic diseases . The structure of the doble helix is very important for the normal life in the cell then studuty his chemical, phisical conformation help to keep the normal process in the cell
5. ScienceDaily (Jan. 28, 2011) — Neutron scattering has been used to investigate the structure of fibre DNA during the melting transition. This is the range of temperatures over which the bonds between base pairs break, or denature, causing the two strands of DNA to separate. The neutron scattering is a technique to study dna secuences and molecular products. This technique offers more details about the molecule of DNA when it is denature, this tecnique shows the temperaturechanges, and the size of the denaturing zones inside the chain of DNA
6. ScienceDaily (Jan. 28, 2011) — Neutron scattering has been used to investigate the structure of fibre DNA during the melting transition. This is the range of temperatures over which the bonds between base pairs break, or denature, causing the two strands of DNA to separate. This technique help to understand the differents cells process and avance in investigations how use the DNA chain for computers parts, how microprocessors in artifical intelligence investigations. This Investigations can offer one New horizont in the robotic and The nanotecnologhy.
7. ScienceDaily (Jan. 28, 2011) — Neutron scattering has been used to investigate the structure of fiber DNA during the melting transition. This is the range of temperatures over which the bonds between base pairs break, or denature, causing the two strands of DNA to separate. The neutron scattering provides the possibility to know the proportion of desnature DNA and intact DNA and the parcial bonds between the nucleotids. Also the neutron scattering have implications for technological development it could also help biological applications, such as predicting where genes might be located on long stretches of DNA sequences."
8. ScienceDaily (Jan. 28, 2011) — Neutron scattering has been used to investigate the structure of fibre DNA during the melting transition. This is the range of temperatures over which the bonds between base pairs break, or denature, causing the two strands of DNA to separate. A similar experiment was made a lot years ago by Rosalind Franklin, who showed that x-ray scattering from DNA and can give clues about of structure of DNA. Based on this work, James Watson and Francis Crick develop the well-known double helix structure of DNA in 1953. Then we can see that the study of DNA structure is something very important in all development of de molecular biology and now the develop of the IA.
10. ScienceDaily (Jan. 21, 2011) — Using a new experimental test structure, biophysicists at JILA have unraveled part of a 15-year mystery in the mechanics of DNA -- just how the molecule manages to suddenly extend to almost twice its normal length. The new test structure should support research on DNA elasticity as a standard for tiny forces and help refine studies of how drugs and other substances bind to DNA. Scientifics of the National Institute of Standards and Technology (NIST) and the University of Colorado at Boulder, explained a very weird an particular propiety of the DNA double helix chain this property overstretching, this phenomenom happen when the DNA molecule are expose to 65 picoNewtons (pN) of force. This force permit the DNA molecule overstretching without losing their properties.
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12. ScienceDaily (Jan. 21, 2011) — Using a new experimental test structure, biophysicists at JILA have unraveled part of a 15-year mystery in the mechanics of DNA -- just how the molecule manages to suddenly extend to almost twice its normal length. The new test structure should support research on DNA elasticity as a standard for tiny forces and help refine studies of how drugs and other substances bind to DNA. The scientifics say the findings and the new DNA test structure will support NIST efforts to develop an official picoNewton-scale force standard that is traceable to the International System of Units. A picoNewton is one-trillionth of a newton, the unit of forceDNA is already used informally as a calibration standard for atomic force microscopes, and investigate how forces of pressure and tension can change the structure of the DNA.
14. MEDICAL UTILITY The neutrons stretching is a very important tecnique of exploration and identification of the DNA structure this can used to determinate possibles mutation an alteration in genes, that can caused many genetic diseases, also can the studies of the DNA can help to prevent the anormal mithosis and the anormal replication of the DNA structure.
15. MEDICAL UTILITY Theknowledge of DNA can open one very wide word of aplication in the robotics because if we can use the DNA in one pc we can get to one new level of artificial inteligence for improve the human life and the technology. It can use the ADN structure in treatments for cancer, VIH and rare degenerative disease because we will can manipulate the replication and fix the mutation in DNA
16. MEDICAL UTILITY The study of stretching in DNA can help in the investigation in how reacts the body in xtreme conditions how high temperature forces in the space, high pressure undersea, all this forces generate in the DNA changes in his structure and in cellular metabolism, because it alters the process of replication of DNA and protein synthesis.
17. MEDICAL UTILITY The studies of the human genoma has helped to find many diferrentes genes, and inside this the nucleicacids structure for help in much diagnosis in genetic, autoimmune and diseases. Findtrataments and therapies for get a better life quality.
18. ScienceDaily, Your source for the lastests research news, United States.[Index]. New England journal of medicine, United States ( index) MARTINEZ S, Lina María. Biología Molecular. 6 ed. Medellín .UPB. Facultad de Medicina, 2011. p 74-81
