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Breezing	
  Co.,	
  Tempe,	
  Arizonawww.breezing.co
1
The	
  Motivation
www.breezing.co
• People	
  spend	
  ~$600	
  billion	
  per	
  year,	
  yet	
  most	
  are	
  frustrate...
The	
  Problem
How	
  much	
  
should	
  I	
  eat?
How	
  much	
  should	
  I	
  
exercise?
www.breezing.co
Why	
  is	
  m...
~	
  80% ~ 10	
  % < 10	
  %	
  (sedentary)
Total	
  energy	
  expenditure	
  (TEE)
= -­‐
Weight Caloric	
  Intake
+ +
Res...
History	
  of	
  Measuring	
  Energy	
  Expenditure
1770’s
Law  of  the  
conservation  of  
energy  à
First  Human  
Cal...
~	
  80% ~ 10	
  % < 10	
  %	
  (sedentary)
Total	
  energy	
  expenditure	
  (TEE)
= -­‐
Weight Caloric	
  Intake
+ +
Res...
Resting Energy Expenditure (REE)
Resting Metabolic Rate (RMR)
Food	
  +
Oxygen
Carbon	
  
Dioxide
+  ATP  (heat),  storage...
Energy	
  management:	
  Cardio-­‐Pulmonary	
  System
• VO2
consumed  oxygen  rate  
• VCO2
produced  carbon  dioxide  rat...
Indirect	
  Calorimetry	
  Principle
Weir,  J.  B.  D.  (1949).  "New  Methods  For  Calculating   Metabolic  Rate  With  ...
Direct	
  Calorimetry	
  vs.	
  Indirect	
  Calorimetry
Indirect	
  Heat	
  
Measurement
CO2
O2
Direct	
  Heat	
  
Measure...
Direct	
  Calorimetry	
  vs.	
  Indirect	
  Calorimetry
Direct	
  Heat	
  
Measurement
Indirect	
  Heat	
  
Measurement
CO...
Oxygen
Carbon
Dioxide Oxygen
Carbon
Dioxide
1700	
  kCal/day 1200	
  kCal/day
Your	
  metabolism	
  =	
  
Your	
  energy	
...
ExerciseGenetics	
  
Diet
Drugs,	
  substances	
  
Pregnancy
Informacion	
  from	
  Sport	
  Nutrition	
  for	
  Health	
 ...
14
www.breezing.co
Tracking	
  Metabolism	
  for	
  Better	
  Health
Diet
Changes	
  in	
  diet	
  can	
  significantly	
 ...
GJODMS,  March,  2015
Tracker	
  for	
  Resting	
  Energy	
  Expenditure	
  (REE)	
  or	
  
Resting	
  Metabolic	
  Rate
15
GJODMS,  March,  2015
The	
  Tracker	
  for	
  
Energy	
  Expenditure	
  
(EE)	
  demonstrated	
  
~100%	
  accuracy
16
17
Moscow	
  Hospital	
  -­‐ 2014
Link	
  a	
  video:	
  hUps://yadi.sk/i/AS_kZZKddY3DA
Other	
  independent	
  validation...
18
Grupo	
  GAYTA/COINCIDE group,	
   México	
  -­‐ 2014
Other	
  independent	
  validations	
  (case	
  #2)
www.breezing....
Other	
  independent	
  validations	
  (case	
  #3)
19
Comparison	
  with	
  Fitmate	
  (Cosmed)	
  -­‐ 2014
Difference	
 ...
20
Other	
  groups/institutions	
  using	
  Breezing
British	
  
Columbia
Vincennes
University
www.breezing.co
Importance	
  of	
  Metabolism	
  for	
  Weight	
  Management
Resting	
  Metabolic	
  Rate	
  (RMR)	
  =	
  “Metabolism”	
...
Food
Total	
  Energy	
  Expenditure	
  (TEE)	
  =	
  
Calories	
  burned
Calorie
Intake
PA
REE
Physical	
  Activity
Metabo...
Weight Target	
  Weight
1
Weight	
  maintenance
1 2
Weight	
  	
  loss1
2
3
REE	
  Drop	
  =	
  
No	
  weight	
  loss2
Tim...
1
2
Weight	
  maintenance Weight	
  	
  loss
Weight
Time
Target	
  Weight
1
2
3’
3’
REE	
  Increase	
  =	
  
Weight	
  los...
1 2 3 4 5 6
0
20
40
60
80
100
Mean:  85.1%
Standard  Deviation:  2.9%
REE  /  TEE  (%)
Subject  (#)
Most	
  of	
  daily	
 ...
1 2 3 4 5 6
0
20
40
60
80
100
Mean:  85.1%
Standard  Deviation:  2.9%
REE  /  TEE  (%)
Subject  (#)
1 2 3 4 5 6 7
0
4
8
12...
Food
Total	
  Energy	
  Expenditure	
  (TEE)	
  =	
  
Calories	
  burned
Calorie
Intake
PA
REE
Physical	
  Activity	
  
Me...
Total	
  Energy	
  Expenditure	
  (TEE)
P
A
REE
Physical	
  Activity
Metabolism
Food-­‐induced	
  Thermogenesis
28
Metabol...
How	
  we	
  can	
  increase	
  metabolism	
  and	
  reverse	
  sedentary	
  
lifestyles	
  without	
  drastically	
  alte...
Jessica and Andrew
Troy, Personal Trainer
Gabriel
Olympic Diver, Mexico
Fang, pregnant mom
(episode 1, episode II)
Dr. Sab...
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Metalism Tracker Breezing - Educational

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An educational overview of metabolism tracking.

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Metalism Tracker Breezing - Educational

  1. 1. Breezing  Co.,  Tempe,  Arizonawww.breezing.co 1
  2. 2. The  Motivation www.breezing.co • People  spend  ~$600  billion  per  year,  yet  most  are  frustrated  with  the  results • Most  people  know  weight  management  requires  balanced  diet  and  exercise. • 2.1  billion  people,  30%  of  the  world  population,   were  overweight  or  obese  in   2013   2  out  3  Americans  are  overweight  or  Obese 2
  3. 3. The  Problem How  much   should  I  eat? How  much  should  I   exercise? www.breezing.co Why  is  my  weight   is  like  yo-­‐yo? 3
  4. 4. ~  80% ~ 10  % < 10  %  (sedentary) Total  energy  expenditure  (TEE) = -­‐ Weight Caloric  Intake + + Resting  (REE) Thermogenesis Physical  Activity Affordable  &  Mobile   Technologies Affordable  &  Mobile   Technologies The  need  …. www.breezing.co 4 (sedentary)
  5. 5. History  of  Measuring  Energy  Expenditure 1770’s Law  of  the   conservation  of   energy  à First  Human   Calorimetry Lavoisier  &   Laplace Other  Direct   Calorimetry   Efforts: Airflow,  water  flow,   water  storage,  and   gradient  layer   calorimeter 1900’s   Claude  Douglas: Gold  Standard  Indirect   Calorimetry  Method CO2 O2 + Analyzers 1890’s   Atwater  &  Rosa Wesleyan  Univ.:  First   important  work  of  Direct   Calorimetry + Analyzers 1940   Indirect  Calorimetry: Open  circuit   spirometry CO2 O2 Indirect   calorimetry: Computer-­based   Instrumentation (Breath-­by-­ breath) 1980 2000         2010 Portable  Breath-­by-­ Breath  Instrumentation CO2 O2 2014 $(10-­‐35)K 5 $350 www.breezing.co First  Mobile   Metabolism   Tracker
  6. 6. ~  80% ~ 10  % < 10  %  (sedentary) Total  energy  expenditure  (TEE) = -­‐ Weight Caloric  Intake + + Resting  (REE) Thermogenesis Physical  Activity Affordable  &  Mobile   Technologies Affordable  &  Mobile   Technologies The  need  …. www.breezing.co 6 (sedentary)
  7. 7. Resting Energy Expenditure (REE) Resting Metabolic Rate (RMR) Food  + Oxygen Carbon   Dioxide +  ATP  (heat),  storage O2 CO2 Resting  Metabolism: ✓ Sustains  life ✓ Majority  of  our  daily  total  energy   expenditure • VO2 consumed   oxygen  rate   • VCO2 produced  carbon   dioxide  rate 7 How  does  it  work? •Indirect  calorimetry  (Breezing  measures   consumed  oxygen  rate  and  produced   carbon  dioxide  rate) •Recommended  by  AND,  WHO,  ACSM,   ADA www.breezing.co
  8. 8. Energy  management:  Cardio-­‐Pulmonary  System • VO2 consumed  oxygen  rate   • VCO2 produced  carbon  dioxide  rate Right  Side   of  Heart Lungs CaO2  -­ CvO2 =  5  mL  O2  per  100  mL CO2 CO2 CO2 O2 O2 O2 O2 Muscle  and Tissues Left  Side   of  Heart Energy  (ATP) 8 www.breezing.co
  9. 9. Indirect  Calorimetry  Principle Weir,  J.  B.  D.  (1949).  "New  Methods  For  Calculating   Metabolic  Rate  With  Special  Reference  To  Protein  Metabolism."  Journal  Of   Physiology-­London  109(1-­2):  1-­9. Weir,  J.  B.  D.  (1990).  "Nutrition  Metabolism  Classic  -­ New  Methods  For  Calculating   Metabolic-­Rate  With  Special  Reference  To  Protein-­ Metabolism."  Nutrition  6(3):  213-­221. REE  (kCal/day)  =  [3.9  (VO2)  +  1.1  (VCO2)]  x  1.44 VO2:  consumed  oxygen  rate  (mL/min) VCO2:  produced  carbon  dioxide  rate  (mL/min) Weir  Equation: Resting  Energy  Expenditure: 9 www.breezing.co
  10. 10. Direct  Calorimetry  vs.  Indirect  Calorimetry Indirect  Heat   Measurement CO2 O2 Direct  Heat   Measurement 10 www.breezing.co
  11. 11. Direct  Calorimetry  vs.  Indirect  Calorimetry Direct  Heat   Measurement Indirect  Heat   Measurement CO2 O2 2717  kCal/day   2723  kCal/day   1900  -­‐ Atwater  &  Rosa’   research:   Energy  expenditure   of  3   men  who  lived  in  the   calorimeter  for  40  days Error:  +/-­‐ 0.2  %   *  Other  researchers’  experiments:  Error  =  +/-­‐ 1% 11 Science  demonstrated  that  direct  calorimetry  is  equivalent  to  indirect  calorimetry
  12. 12. Oxygen Carbon Dioxide Oxygen Carbon Dioxide 1700  kCal/day 1200  kCal/day Your  metabolism  =   Your  energy   =  Your  Fire Why  track  metabolism? Weight:  112  lbs Height:  5’  6’’ Age:  29  years 12 www.breezing.co Different  people  have   different   metabolisms
  13. 13. ExerciseGenetics   Diet Drugs,  substances   Pregnancy Informacion  from  Sport  Nutrition  for  Health  and  Performance,  M.  Manore,  N.  Mayer,  J.  Thompson  -­‐ 2009 Hormones 13 www.breezing.co Why  track  metabolism? Different  factors  can   affect  metabolism
  14. 14. 14 www.breezing.co Tracking  Metabolism  for  Better  Health Diet Changes  in  diet  can  significantly  change  metabolism.  For   example,  a  crash  diet  can  cause  drastic  reduction  in   metabolic  rate,  leading  to  a  “weight  loss  plateau”.  See   slides  23-­‐24,  and  “Case  Studies”  Case  #8. Exercise Exercise  can  affect  metabolism. For  example,  muscle-­‐ building  increases  metabolism  and  High  Intensity   Intermittent  Training  (HIIT)  creates  an  “afterburn”  effect. See  slides  27-­‐28,  and  “Case  Studies”  Cases #6  and #7. Hormones/medication Hormonal  changes  and  medications  can  change   metabolism.  Monitoring  metabolism  helps  screen  for   potential    hyper-­‐ or  hypo-­‐thyroidism.  See  “Case   Studies” Case  #5. Pregnancy Metabolism changes  significantly throughout  pregnancy   and  after  giving  birth.  Tracking  metabolism  helps  the   mother  maintain  and  achieve  the  proper  weight  for  the   baby’s  healthy  growth.  See  “Case  Studies”  Case  #3.
  15. 15. GJODMS,  March,  2015 Tracker  for  Resting  Energy  Expenditure  (REE)  or   Resting  Metabolic  Rate 15
  16. 16. GJODMS,  March,  2015 The  Tracker  for   Energy  Expenditure   (EE)  demonstrated   ~100%  accuracy 16
  17. 17. 17 Moscow  Hospital  -­‐ 2014 Link  a  video:  hUps://yadi.sk/i/AS_kZZKddY3DA Other  independent  validations  (case  #1) www.breezing.co Professionals in Moscow’s Hospital have probed that Breezing functions at the same level of expensive metabolic carts (100 times more expensive than Breezing)
  18. 18. 18 Grupo  GAYTA/COINCIDE group,   México  -­‐ 2014 Other  independent  validations  (case  #2) www.breezing.co Atlas soccer team’s Sports Nutrition Team (COINCIDE) has demonstrated the importance of measuring metabolism in Sports Nutrition
  19. 19. Other  independent  validations  (case  #3) 19 Comparison  with  Fitmate  (Cosmed)  -­‐ 2014 Difference  between  Breezing  and  Fitmate  of  4  kCal/daywww.breezing.co
  20. 20. 20 Other  groups/institutions  using  Breezing British   Columbia Vincennes University www.breezing.co
  21. 21. Importance  of  Metabolism  for  Weight  Management Resting  Metabolic  Rate  (RMR)  =  “Metabolism”  =  Resting  Energy  Expenditure  (REE) 21 www.breezing.co
  22. 22. Food Total  Energy  Expenditure  (TEE)  =   Calories  burned Calorie Intake PA REE Physical  Activity Metabolism   (>75%) Energy  Balance  and  Weight  Loss     Food-­‐induced  Thermogenesis 22 www.breezing.co
  23. 23. Weight Target  Weight 1 Weight  maintenance 1 2 Weight    loss1 2 3 REE  Drop  =   No  weight  loss2 Time 3 1-­‐ Seagle,  H.  M.,  G.  W.  Strain,  et  al.  (2009).  "Position   of  the  America  Dietetic   Association:  Weight  Management."  Journal  Of  The  American  Dietetic   Association  109(2):   330-­‐346. 2  -­‐ Elliot,   D.  L.,  L.  Goldberg,   et  al.  (1989).  "SUSTAINED  DEPRESSION  OF  THE  RESTING  METABOLIC-­‐RATE  AFTER  MASSIVE  WEIGHT-­‐LOSS."  American  Journal  Of  Clinical   Nutrition   49(1):  93-­‐96. -­‐ Heshka,  S.,  M.  U.  Yang,  et  al.  (1990).  "WEIGHT-­‐LOSS  AND  CHANGE  IN  RESTING  METABOLIC-­‐RATE."  American  Journal   Of  Clinical  Nutrition   52(6):  981-­‐986. -­‐ Leibel,   R.  L.,  M.  Rosenbaum,  et  al.  (1995).  "CHANGES  IN  ENERGY-­‐EXPENDITURE   RESULTING  FROM  ALTERED  BODY-­‐WEIGHT."  New  England  Journal  of  Medicine   332(10):  621-­‐628. Unsustainable  Weight  Loss  Problem 23 Metabolism  can  drop  ! www.breezing.co
  24. 24. 1 2 Weight  maintenance Weight    loss Weight Time Target  Weight 1 2 3’ 3’ REE  Increase  =   Weight  loss Sustainable  Weight  Loss Monitoring  Resting   Energy  Expenditure 24 www.breezing.co
  25. 25. 1 2 3 4 5 6 0 20 40 60 80 100 Mean:  85.1% Standard  Deviation:  2.9% REE  /  TEE  (%) Subject  (#) Most  of  daily  total  energy  expenditure  (TEE)  is   spent  to  maintain  basic  body  functions (energy  expenditure  at  resting  state,  EER  or  REE) How  Sedentary  Are  We? Total  Energy  Expenditure* Resting  Energy  Expenditure  (REE) Thermogenesis Physical  Activity 75  % 15  % ~10  % *McArdle,  Katch &  Katch,  Ex.  Physiology,   2009   1 2 3 4 5 6 7 0 4 8 12 16 20 24 Driving Bench  Work Watching  TV Walking Office  Work Sleeping Daily  Activity  (hs) Subject  (#) Leisure Lab  Work Work  from  Arizona  State  University,  2013
  26. 26. 1 2 3 4 5 6 0 20 40 60 80 100 Mean:  85.1% Standard  Deviation:  2.9% REE  /  TEE  (%) Subject  (#) 1 2 3 4 5 6 7 0 4 8 12 16 20 24 Driving Bench  Work Watching  TV Walking Office  Work Sleeping Daily  Activity  (hs) Subject  (#) Leisure Most  of  daily  total  energy  expenditure  (TEE)  is   spent  to  maintain  basic  body  functions (energy  expenditure  at  resting  state,  REE) How  Sedentary  Are  We? Total  Energy  Expenditure* Resting  Energy  Expenditure  (REE) Thermogenesis Physical  Activity >  80  % <  5  %~10  % *Exercise  Physiology,   McArdle,  Katch &  Katch 15%  à 5% 75%  à >80% Work  from  Arizona  State  University,  2013
  27. 27. Food Total  Energy  Expenditure  (TEE)  =   Calories  burned Calorie Intake PA REE Physical  Activity   Metabolism   (>75%) (80-­‐90  %  in   sedentary   persons) Energy  Balance  – How  we  can  modify  it? Food-­‐induced  Thermogenesis 27 www.breezing.co
  28. 28. Total  Energy  Expenditure  (TEE) P A REE Physical  Activity Metabolism Food-­‐induced  Thermogenesis 28 Metabolism  (RMR)  and  Physical  Activity* P A REE Exercise P A REE *Speakman et.al.,  Proceeding  of  the  nutrition  society,  2003,  62,  621-­‐634  (Fig.2  reproduction) Total Effect  of Sustained Exercise www.breezing.co
  29. 29. How  we  can  increase  metabolism  and  reverse  sedentary   lifestyles  without  drastically  altering  our  schedules? 29 High  Intensity  Intermittent  Training  (HIIT) Work  from  Arizona  State  University,  2013 www.breezing.co
  30. 30. Jessica and Andrew Troy, Personal Trainer Gabriel Olympic Diver, Mexico Fang, pregnant mom (episode 1, episode II) Dr. Sabagh Real  User  Stories

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