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Welcome
Community College Program
Annual Community College Program Day
        Organizing Committee

 • Sonia Wallman – Executive Director NBC2
 • Elaine Johnson – Bio-Link Director
 • Russ Read – National Center, NC BioNetwork
 • Lance Hartford – MassBioEd Foundation
 • Margaret Bryans – PI NBC2, Montgomery County
   Community College
 • Lisa Seidman – Madison Area Technical College
 • Tim Dubuque - NBC2
Massachusetts BioPharma Employment
             Continues Growth

The industry
weathered
the 2009
downturn
without an
employment
drop.




  53%
 Growth
 since
               Source: U.S. Census, County Business Patterns and MassBio formula and analysis.
  2002         *2011 figure is a preliminary estimate based on review of Massachusetts ES-202 data for 2010-2011.
Biotechnology R&D Employment

                                                 2007                         2010
According to the
Bureau of Labor
                        CA                     19,134                       21,616
Statistics’             CT                      2,452                        1,582
Quarterly Census        MA                     24,565                       26,807
of Employment &
Wage (QCEW)             MD                     10,154                        9,469
data, Massachus         MI                      4,670                        2,759
etts leads the
nation in               MO                      4,262                        3,874
biotechnology           NJ                      8,567                        9,224
research &
development
                        NY                      2,679                        3,553
employment.             NC                      7,042                        6,275
                        PA                     15,902                       12,776
                        WA                      2,499                        3,730


                             Source: U.S. Bureau of Labor Statistics, Quarterly Census of Employment and Wages (QCEW)
Drug Development Pipeline, August 2011
                    Candidate medicines of Massachusetts-headquartered* companies, by clinical trials
                                                        stage
                                          Pre-Clinical                             316
Massachusetts-
                                          Phase I                                  216
headquartered
companies*                                Phase II                                 275

account for about                         Phase III                                 76
10% of the U.S.                           Pending Approval                          14
drug development
pipeline and 5%          Massachusetts-headquartered companies’ share of U.S. and Global drug
of the global                                   development pipeline
pipeline.
                                          Total Trials        PC           I      II      III     PA
                         % of US               9.41%         11.00%      11.99%   8.26%   8.46%   3.89%
                         % of Global           4.91%          5.88%       6.43%   4.56%   3.52%   1.44%


                      * There are many drugs in development in Massachusetts by companies with headquarters
                      located outside of Massachusetts. These candidate drugs are not included in any
                      Massachusetts pipeline estimates found in this report.


                      Source: MedTrack Online, Life Sciences Analytics, Inc.
Massachusetts Pipeline by Therapeutic
                              Area
                                                                   Total Trials Companies
Of the 897 drugs in   Cancer                                                 383        59
the Massachusetts     Central Nervous System                                  91        35
pipeline, 42.7%       Infectious                                              84        30
are cancer drugs.     Autoimmune and Inflammation                             61        33
                      Metabolic/Endocrinology                                 47        23
Drugs intended for    Ophthalmology and Optometry                             32        13
the Central           Respiratory and Pulmonary System                        32        20
Nervous System        Blood and Lymphatic System                              30        16
(CNS) therapeutic     Cardiovascular & Circulatory                            25        36
area are next at      Musculo-Skeletal-Disorders                              24        11
10.1% of the          Digestive                                               19        15
pipeline.             Dermotology                                             18        15
                      Kidney & Genito-Urinary                                 13        10
                      Genetic Diseases & Dysmorphic Syndromes                 11         6
                      Substance Abuse                                         10         5
                      Women's Health                                           9         6
                      Miscellaneous                                            8         7


                                                            Source: MedTrack Online, Life Sciences Analytics, Inc.
Venture Capital Investment

$1.071 billion
invested in MA
biotechs in 2011
is an historic
high.




 $8.054
 billion since
 2002




                   Source Data: 2011 PricewaterhouseCoopers, National Venture Capital Association, MoneyTreeTM Report, Historical Trend Data, and
                                                                                                                                MassBio analysis.
MA Share of the Biotech VC Dollar


MA biotechs
received 22.6%
of all VC biotech
financing, just
below the 2010
all-time high.




                              Source: 2011 PricewaterhouseCoopers, National Venture Capital
                    Association, MoneyTreeTM Report, Historical Trend Data, MassBio analysis.
Leading BioPharma Employers (MA), 2011
                   1. Genzyme (Sanofi)                                          4,356
                   2. Pfizer                                                    2,600
                   3. Biogen Idec                                               2,300
                   4. Novartis                                                  2,100
MA has benefited   5. Thermo Fisher Scientific                                  1,700
from the pharma    6. Shire                                                     1,500
industry’s         7. Vertex                                                    1,310
embrace of         8. EMD Millipore                                             1,237
biotechnology.     9. Parexel International                                     1,200
                   10. Millenium: Takeda Oncology                               1,050
                   11. Charles River Laboratories                                 970
                   12. AstraZeneca                                                900
                   13. EMD Serono                                                 850
                   14. Hologic                                                    800
                   15. Abbott Laboratories                                        750
                   16. Sunovion Pharmaceuticals (DSP)                             690
                   17. Nova Biomedical                                            631
                   18. Cubist                                                     626
                   19. Lantheus                                                   550
                   19. Merck                                                      330
                   20. Bristol-Myers Squibb                                       320



                    Sources: MassBio, membership reports, survey, Boston Business Journal Book of Lists, 2011.
Mass Biomanufacturing

Of the top 11
biopharma
manufacturing
states, Massachu
setts was one of
just four which
added
manufacturing
jobs in the last
decade
BioPharma Industry Impact in MA
The estimated
average
salary in the
biopharma
industry is                              $4,615,364,513 in payroll (2010)
77% higher
than the
estimated
                                         $95,628 in average salary (2010)
state average
salary of
$53,834.                                            Source: U.S. Census, County Business Patterns, MassBio estimate using 2009 base data .




                M a s s a c h u s e tts E x p o rts , 2 0 1 0
                A ll C o m m o d itie s                                                                              2 6 ,2 5 6 ,3 7 0 ,2 0 1
                O p tic , P h o to E tc , M e d ic O r S u rg ic a l In s trm e n ts E tc                              5 ,3 2 4 ,5 1 1 ,9 4 0    2 0 .2 0 %
                In d u s tria l M a c h in e ry, In c lu d in g C o m p u te rs                                        4 ,6 0 1 ,7 1 5 ,0 8 6
                E le c tric M a c h in e ry E tc ; S o u n d E q u ip ; T v E q u ip ; P ts                            4 ,5 1 8 ,6 6 2 ,8 8 0
                P h a rm a c e u tic a l P ro d u c ts                                                                 2 ,1 3 6 ,3 0 6 ,4 5 6      8 .1 0 %
                                                                                                                                Source: MassExport Center
Why Massachusetts?

                        500+
                        430+
                       Biopharma
                        Biotech
                       Companies


  122                                            Top 5
                                                 Top
                                                     5
                                                NIH funded
Colleges &                                      NIH funded
                                                 Research
Universities                                     Research
                                                 Hospitals
                                                 Hospitals




   1st in                                     1st in
                                          Venture Capital
  Education
                                           & SBIR funds
                                             federal research
   Level of
                                            funds per worker
                                            per worker
  Workforce
  workforce (US)


                       Supportive
               Local, State Government

                   Life Sciences Initiative
                       Biotech Caucus
The $1 Billion Massachusetts Life
                          Sciences Initiative

Over time, the
industry
demonstrated its
value, commitme
nt to the
region, and
promise for the
future . . . and
state government
responded.                     • 10 years
                               • $1 billion
                              Investment
Education and Workforce Development
              Initiatives

 U.S. Department of Labor to receive the Trade Adjustment Assistance
 Community College and Career Training Grant. $20M

 The Metro Boston Skilled Careers in Life Sciences (SCILS) initiative $5M – Life
 Sciences Center & Quincy College

 Mass Life Science Center Internship Program - since the program first launched
 in 2009, the Center has placed 794 interns at more than 250 companies
 throughout Massachusetts!

 MassBioEd Foundation’s industry endorsement of eight community college
 programs
Northeast Biomanufacturers and
Community Colleges with Biomanufacturing

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Massachusetts Leads in Biopharma Innovation and Job Growth

  • 2. Annual Community College Program Day Organizing Committee • Sonia Wallman – Executive Director NBC2 • Elaine Johnson – Bio-Link Director • Russ Read – National Center, NC BioNetwork • Lance Hartford – MassBioEd Foundation • Margaret Bryans – PI NBC2, Montgomery County Community College • Lisa Seidman – Madison Area Technical College • Tim Dubuque - NBC2
  • 3.
  • 4. Massachusetts BioPharma Employment Continues Growth The industry weathered the 2009 downturn without an employment drop. 53% Growth since Source: U.S. Census, County Business Patterns and MassBio formula and analysis. 2002 *2011 figure is a preliminary estimate based on review of Massachusetts ES-202 data for 2010-2011.
  • 5. Biotechnology R&D Employment 2007 2010 According to the Bureau of Labor CA 19,134 21,616 Statistics’ CT 2,452 1,582 Quarterly Census MA 24,565 26,807 of Employment & Wage (QCEW) MD 10,154 9,469 data, Massachus MI 4,670 2,759 etts leads the nation in MO 4,262 3,874 biotechnology NJ 8,567 9,224 research & development NY 2,679 3,553 employment. NC 7,042 6,275 PA 15,902 12,776 WA 2,499 3,730 Source: U.S. Bureau of Labor Statistics, Quarterly Census of Employment and Wages (QCEW)
  • 6. Drug Development Pipeline, August 2011 Candidate medicines of Massachusetts-headquartered* companies, by clinical trials stage Pre-Clinical 316 Massachusetts- Phase I 216 headquartered companies* Phase II 275 account for about Phase III 76 10% of the U.S. Pending Approval 14 drug development pipeline and 5% Massachusetts-headquartered companies’ share of U.S. and Global drug of the global development pipeline pipeline. Total Trials PC I II III PA % of US 9.41% 11.00% 11.99% 8.26% 8.46% 3.89% % of Global 4.91% 5.88% 6.43% 4.56% 3.52% 1.44% * There are many drugs in development in Massachusetts by companies with headquarters located outside of Massachusetts. These candidate drugs are not included in any Massachusetts pipeline estimates found in this report. Source: MedTrack Online, Life Sciences Analytics, Inc.
  • 7. Massachusetts Pipeline by Therapeutic Area Total Trials Companies Of the 897 drugs in Cancer 383 59 the Massachusetts Central Nervous System 91 35 pipeline, 42.7% Infectious 84 30 are cancer drugs. Autoimmune and Inflammation 61 33 Metabolic/Endocrinology 47 23 Drugs intended for Ophthalmology and Optometry 32 13 the Central Respiratory and Pulmonary System 32 20 Nervous System Blood and Lymphatic System 30 16 (CNS) therapeutic Cardiovascular & Circulatory 25 36 area are next at Musculo-Skeletal-Disorders 24 11 10.1% of the Digestive 19 15 pipeline. Dermotology 18 15 Kidney & Genito-Urinary 13 10 Genetic Diseases & Dysmorphic Syndromes 11 6 Substance Abuse 10 5 Women's Health 9 6 Miscellaneous 8 7 Source: MedTrack Online, Life Sciences Analytics, Inc.
  • 8. Venture Capital Investment $1.071 billion invested in MA biotechs in 2011 is an historic high. $8.054 billion since 2002 Source Data: 2011 PricewaterhouseCoopers, National Venture Capital Association, MoneyTreeTM Report, Historical Trend Data, and MassBio analysis.
  • 9. MA Share of the Biotech VC Dollar MA biotechs received 22.6% of all VC biotech financing, just below the 2010 all-time high. Source: 2011 PricewaterhouseCoopers, National Venture Capital Association, MoneyTreeTM Report, Historical Trend Data, MassBio analysis.
  • 10. Leading BioPharma Employers (MA), 2011 1. Genzyme (Sanofi) 4,356 2. Pfizer 2,600 3. Biogen Idec 2,300 4. Novartis 2,100 MA has benefited 5. Thermo Fisher Scientific 1,700 from the pharma 6. Shire 1,500 industry’s 7. Vertex 1,310 embrace of 8. EMD Millipore 1,237 biotechnology. 9. Parexel International 1,200 10. Millenium: Takeda Oncology 1,050 11. Charles River Laboratories 970 12. AstraZeneca 900 13. EMD Serono 850 14. Hologic 800 15. Abbott Laboratories 750 16. Sunovion Pharmaceuticals (DSP) 690 17. Nova Biomedical 631 18. Cubist 626 19. Lantheus 550 19. Merck 330 20. Bristol-Myers Squibb 320 Sources: MassBio, membership reports, survey, Boston Business Journal Book of Lists, 2011.
  • 11. Mass Biomanufacturing Of the top 11 biopharma manufacturing states, Massachu setts was one of just four which added manufacturing jobs in the last decade
  • 12. BioPharma Industry Impact in MA The estimated average salary in the biopharma industry is $4,615,364,513 in payroll (2010) 77% higher than the estimated $95,628 in average salary (2010) state average salary of $53,834. Source: U.S. Census, County Business Patterns, MassBio estimate using 2009 base data . M a s s a c h u s e tts E x p o rts , 2 0 1 0 A ll C o m m o d itie s 2 6 ,2 5 6 ,3 7 0 ,2 0 1 O p tic , P h o to E tc , M e d ic O r S u rg ic a l In s trm e n ts E tc 5 ,3 2 4 ,5 1 1 ,9 4 0 2 0 .2 0 % In d u s tria l M a c h in e ry, In c lu d in g C o m p u te rs 4 ,6 0 1 ,7 1 5 ,0 8 6 E le c tric M a c h in e ry E tc ; S o u n d E q u ip ; T v E q u ip ; P ts 4 ,5 1 8 ,6 6 2 ,8 8 0 P h a rm a c e u tic a l P ro d u c ts 2 ,1 3 6 ,3 0 6 ,4 5 6 8 .1 0 % Source: MassExport Center
  • 13. Why Massachusetts? 500+ 430+ Biopharma Biotech Companies 122 Top 5 Top 5 NIH funded Colleges & NIH funded Research Universities Research Hospitals Hospitals 1st in 1st in Venture Capital Education & SBIR funds federal research Level of funds per worker per worker Workforce workforce (US) Supportive Local, State Government Life Sciences Initiative Biotech Caucus
  • 14. The $1 Billion Massachusetts Life Sciences Initiative Over time, the industry demonstrated its value, commitme nt to the region, and promise for the future . . . and state government responded. • 10 years • $1 billion Investment
  • 15. Education and Workforce Development Initiatives U.S. Department of Labor to receive the Trade Adjustment Assistance Community College and Career Training Grant. $20M The Metro Boston Skilled Careers in Life Sciences (SCILS) initiative $5M – Life Sciences Center & Quincy College Mass Life Science Center Internship Program - since the program first launched in 2009, the Center has placed 794 interns at more than 250 companies throughout Massachusetts! MassBioEd Foundation’s industry endorsement of eight community college programs
  • 16. Northeast Biomanufacturers and Community Colleges with Biomanufacturing

Editor's Notes

  1. Representatives of many of the Massachusetts community colleges are present here today: Middlesex CC, Minuteman Technical Institute, Mount Wachusett CC, Quincy College, Roxbury CC, Springfield Tech, Northern Essex CC, Massasoit CC, Berkshire CC, Bristol CC, Bunker Hill CC, and Holyoke CC. In addition, many other community colleges in the Northeastern US are represented, including Great Bay CC in NH; the Community College of RI; Manchester CC in CT; Hudson Valley CC in NY; Middlesex County and Bergen CC in NJ, and last but not least Bucks and Montgomery County CC in PA. Maggie Bryans is the Principal Investigator of the NBC2 and has put this meeting together for all of us.There are several partners from industry here, as well: former student and biomanufacturing apprentice, David Haddad at Millennium Pharmaceuticals, priceless colleague from engaged partner Lonza, Ben Locwin; harmonization of skill standards and strategic planning meeting participant, John Sauers from Abbott and Bill Chambrione from Shire who has supported the new 360hr/12 week adult biomanufacturing certificate at Minuteman Technical Institute. Welcome to all and back to Lance and Russ to lead our first panel, Industry – Realities and Expectations.