This document discusses common presentations in primary care practice, including aches and pains, headaches, fatigue, gastrointestinal symptoms, hyperventilation, and pseudo-neurological symptoms. It notes that cases are often due to the interaction of mind, body, and mental state. The document provides guidance on managing anxiety, depression, and pain-predominant cases with medications like SSRIs, mirtazapine, antipsychotics, and benzodiazepines. It cautions about risks like manic switching, alcohol withdrawal, and addiction when treating insomnia.