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CHAPTER 15:

 DIGESTION
& NUTRITION
Digestion
   the breakdown of food into simpler
   compounds and their absorption
  2 Types of Digestion
     1. Physical or Mechanical
        - the breakdown of food from big
          pieces into smaller pieces
    2. Chemical
       - the breakdown of food into their
         simplest substance
mouth
        salivary
         glands
                   pharynx

                   esophagus

                   stomach
liver
                   small intestine
    gall
    bladder

pancreas           large intestine

                   rectum
                   anus
General Characteristics of the Alimentary Canal
4 Layers
   1. Mucosa
       - innermost layer
  2. Submucosa
       - contains many blood vessels and
         nerve fibers
 3. Muscular Layer
       - has 2 layers of muscles
  4. Serosa
        - protects underlying tissue and
          secretes serous fluid
] submucosa
Mouth
 - begins the physical digestion (chewing)
   of food
 Parts of the Mouth
    1. Cheeks
    2. Lips
    3. Tongue
          - contains the taste buds
          - connected to mouth by frenulum
    4. Hard palate
5. Soft palate
      - a muscular partition that closes off
        the nasal cavity when swallowing
6. Uvula
     - the little hangy thing in back of
       the mouth
7. Teeth
     - 20 deciduous
     - 32 permanent
4 Types of Teeth
  1. Incisors          - biting
  2. Cuspids (canines) - tearing
  3. Bicuspids
  4. Molars         }  - grinding
Parts of a Tooth
Salivary Glands
  - secretes saliva
  - moistens food which makes taste possible
  - cleans the mouth
  Salivary Secretions
   - there are 2 types of cells in salivary glands
 1. Serous
       - produces salivary amylase
 2. Mucous
        - produces mucus
3 Major Salivary Glands
  1. Parotid
  2. Sublingual
  3. Submandibular
Digestion in the Mouth
  Mastication – chewing of food begins
                physical digestion
  - salivary glands release salivary amylase
    which begins chemical digestion
    of carbohydrates
Pharynx
  - involved in the swallowing reflex
  3 Parts of the Pharynx
   1. Nasopharynx
   2. Oropharynx
   3. Laryngopharynx
  - once food moves into the pharynx, the
    reflex causes the epiglottis to cover the
    trachea & push the food into the
    esophagus
Esophagus
  - 25 cm long, leads into the stomach
  - begins the process of peristalsis
                              wave-like motion
                                of muscles to
                                move food
Stomach
  Functions
   - begins protein digestion
  - stores food
  - completes physical digestion of food

  4 Parts of the Stomach
  1. Cardiac Region
  2. Fundic Region
  3. Body
  4. Pyloric Region
Gastric Glands
4 Types of cells
 a. mucous cells
     - produce mucus
 b. parietal cells
     - produces HCl
     - produces Intrinsic factor
           - helps absorb Vit. B12
c. chief cells
     - produce pepsinogen
d. G-cells
     - produce gastrin
Digestion in the Stomach
1. Physical
  - peristaltic waves pass over the stomach
    every 15-25 seconds
  - this wave action blends the food into a
    soupy substance called chyme
2. Chemical
   - pepsinogen changes into active pepsin
     in the presence of HCl
   - breaks proteins down into polypeptides
Gastric Absorption
  - some water
  - ions
  - short fatty acids
  - certain drugs (aspirin)
  - alcohol
Regulation of Gastric Secretions
1. Cephalic Phase
   - when you see, smell, think about, or
     taste food, the brain tells the gastric
     glands to produce gastric juices

2. Gastric Phase
   - when food enters the stomach, it
     expands, gastrin is released
   - gastrin causes the release of
     gastric juices from the gastric glands
3. Intestinal Phase
   - when chyme enters sm. int., 2 hormones
     are produced by the intestinal glands,
     secretin & CCK
  - secretin decreases gastric secretions and
    CCK keeps too much food from
    entering the stomach


        Gastric secretion movie
Pancreas
2 Types of Cells
  1. Islets of Langerhans
        - produce insulin & glucagon
  2. Pancreatic Cells
       - secrete pancreatic juices
Pancreatic Juice
  - is a basic solution to neutralize the chyme
  - contains the following enzymes
       - pancreatic amylase       - carbs
       - pancreatic lipase        - lipids

                               }
       - trypsin
       - chymotrypsin
                                     proteins
       - carboxypeptidase
        - pancreatic nuclease      - nucleic acids
Regulation of Pancreas
 - secretin & CCK causes the release of
   pancreatic juices into the sm. int.
Liver
 Functions
  - carbohydrate metabolism
  - lipid metabolism
  - protein metabolism
  - removes damaged RBC’s
  - removes toxins
  - makes bile
Structure of Liver
   - 2 lobes
   - lobes are divided into hepatic lobules
   - 100,000 – 200,000
                 Hepatocyte
                     
Bile
   - made by hepatocytes
  Function
  - emulsifies fat
      breaks big fat globules into small
        fat globules
 Regulation
    - constantly made by liver cells
    - nerve impulse can trigger bile
      production
Gall Bladder




  - stores excess bile from the liver
  - releases bile when CCK is present
Small Intestine
Structure of Sm. Intestine
     - mucosa forms finger-like projections
       called villi
     - each villus contains absorptive cells
       that have microvilli on them
     - goblet cells produce mucus
     - the lacteal is a lymph capillary that
       involves fatty acid absorption
     - intestinal glands secrete intestinal
       juices
Functions of the Small Intestine
1. Segmentation mixes chyme with digestive
   juices, peristalsis moves food through
   sm. int.
2. Completes chemical digestion of food
3. Absorbs 90% of all nutrients
Chemical Digestion in the Small Intestine
1. Carbohydrates
   - pancreatic amylase breaks down
     polysacccharides
   - sucrase, lactase, & maltase made by
     the intestinal glands breaks down
     disaccharides into monosaccharides
2. Proteins
   - aminopeptidase and dipeptidase made
     by the intestinal glands breaks down
     polypeptides into amino acids
3. Lipids
   - pancreatic lipase splits the fatty acids
     from the glycerol
4. Nucleic Acids
   - pancreatic nuclease and intestinal
     nuclease breaks down RNA & DNA into
     nucleotides
Absorption of Nutrients
Weight Loss Surgeries
1. Lab-Band
2. Vertical Sleeve Gastrectomy
3. VSG with duodenal switch
3. Roux-en-Y
Large Intestine
  Structure
Funtions
     - absorption of water and electrolytes
     - contain bacteria that changes waste
       into a semi-solid and produces
       some Vit. K
    - NO DIGESTION OCCURS IN THE
      LARGE INTESTINE
FECES!
 - 75% water
 - bacteria
 - mucus
 - undigested food
 - bile
 - bile pigments
 - cellulose (fiber)
Nutrients
      carbohydrates
      lipids
      proteins
      vitamins
      minerals
      trace elements

Adequate diet – provides sufficient energy
    and nutrients to support optimal
    growth and to maintain and repair
    body tissue
Body    Figure 15.34
Mass
Index

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Physiology CH 15 lecture notes

  • 2. Digestion  the breakdown of food into simpler compounds and their absorption 2 Types of Digestion 1. Physical or Mechanical - the breakdown of food from big pieces into smaller pieces 2. Chemical - the breakdown of food into their simplest substance
  • 3. mouth salivary glands pharynx esophagus stomach liver small intestine gall bladder pancreas large intestine rectum anus
  • 4. General Characteristics of the Alimentary Canal
  • 5. 4 Layers 1. Mucosa - innermost layer 2. Submucosa - contains many blood vessels and nerve fibers 3. Muscular Layer - has 2 layers of muscles 4. Serosa - protects underlying tissue and secretes serous fluid
  • 7. Mouth - begins the physical digestion (chewing) of food Parts of the Mouth 1. Cheeks 2. Lips 3. Tongue - contains the taste buds - connected to mouth by frenulum 4. Hard palate
  • 8. 5. Soft palate - a muscular partition that closes off the nasal cavity when swallowing 6. Uvula - the little hangy thing in back of the mouth 7. Teeth - 20 deciduous - 32 permanent
  • 9.
  • 10. 4 Types of Teeth 1. Incisors - biting 2. Cuspids (canines) - tearing 3. Bicuspids 4. Molars } - grinding
  • 11. Parts of a Tooth
  • 12. Salivary Glands - secretes saliva - moistens food which makes taste possible - cleans the mouth Salivary Secretions - there are 2 types of cells in salivary glands 1. Serous - produces salivary amylase 2. Mucous - produces mucus
  • 13. 3 Major Salivary Glands 1. Parotid 2. Sublingual 3. Submandibular
  • 14. Digestion in the Mouth Mastication – chewing of food begins physical digestion - salivary glands release salivary amylase which begins chemical digestion of carbohydrates
  • 15. Pharynx - involved in the swallowing reflex 3 Parts of the Pharynx 1. Nasopharynx 2. Oropharynx 3. Laryngopharynx - once food moves into the pharynx, the reflex causes the epiglottis to cover the trachea & push the food into the esophagus
  • 16. Esophagus - 25 cm long, leads into the stomach - begins the process of peristalsis  wave-like motion of muscles to move food
  • 17. Stomach Functions - begins protein digestion - stores food - completes physical digestion of food 4 Parts of the Stomach 1. Cardiac Region 2. Fundic Region 3. Body 4. Pyloric Region
  • 18.
  • 19. Gastric Glands 4 Types of cells a. mucous cells - produce mucus b. parietal cells - produces HCl - produces Intrinsic factor - helps absorb Vit. B12
  • 20. c. chief cells - produce pepsinogen d. G-cells - produce gastrin
  • 21. Digestion in the Stomach 1. Physical - peristaltic waves pass over the stomach every 15-25 seconds - this wave action blends the food into a soupy substance called chyme 2. Chemical - pepsinogen changes into active pepsin in the presence of HCl - breaks proteins down into polypeptides
  • 22. Gastric Absorption - some water - ions - short fatty acids - certain drugs (aspirin) - alcohol
  • 23. Regulation of Gastric Secretions 1. Cephalic Phase - when you see, smell, think about, or taste food, the brain tells the gastric glands to produce gastric juices 2. Gastric Phase - when food enters the stomach, it expands, gastrin is released - gastrin causes the release of gastric juices from the gastric glands
  • 24. 3. Intestinal Phase - when chyme enters sm. int., 2 hormones are produced by the intestinal glands, secretin & CCK - secretin decreases gastric secretions and CCK keeps too much food from entering the stomach Gastric secretion movie
  • 26. 2 Types of Cells 1. Islets of Langerhans - produce insulin & glucagon 2. Pancreatic Cells - secrete pancreatic juices
  • 27. Pancreatic Juice - is a basic solution to neutralize the chyme - contains the following enzymes - pancreatic amylase - carbs - pancreatic lipase - lipids } - trypsin - chymotrypsin proteins - carboxypeptidase - pancreatic nuclease - nucleic acids Regulation of Pancreas - secretin & CCK causes the release of pancreatic juices into the sm. int.
  • 28. Liver Functions - carbohydrate metabolism - lipid metabolism - protein metabolism - removes damaged RBC’s - removes toxins - makes bile
  • 29. Structure of Liver - 2 lobes - lobes are divided into hepatic lobules - 100,000 – 200,000 Hepatocyte 
  • 30. Bile - made by hepatocytes Function - emulsifies fat  breaks big fat globules into small fat globules Regulation - constantly made by liver cells - nerve impulse can trigger bile production
  • 31. Gall Bladder - stores excess bile from the liver - releases bile when CCK is present
  • 33. Structure of Sm. Intestine - mucosa forms finger-like projections called villi - each villus contains absorptive cells that have microvilli on them - goblet cells produce mucus - the lacteal is a lymph capillary that involves fatty acid absorption - intestinal glands secrete intestinal juices
  • 34.
  • 35. Functions of the Small Intestine 1. Segmentation mixes chyme with digestive juices, peristalsis moves food through sm. int. 2. Completes chemical digestion of food 3. Absorbs 90% of all nutrients
  • 36. Chemical Digestion in the Small Intestine 1. Carbohydrates - pancreatic amylase breaks down polysacccharides - sucrase, lactase, & maltase made by the intestinal glands breaks down disaccharides into monosaccharides
  • 37. 2. Proteins - aminopeptidase and dipeptidase made by the intestinal glands breaks down polypeptides into amino acids 3. Lipids - pancreatic lipase splits the fatty acids from the glycerol 4. Nucleic Acids - pancreatic nuclease and intestinal nuclease breaks down RNA & DNA into nucleotides
  • 39.
  • 41. 2. Vertical Sleeve Gastrectomy
  • 42. 3. VSG with duodenal switch
  • 44. Large Intestine Structure
  • 45. Funtions - absorption of water and electrolytes - contain bacteria that changes waste into a semi-solid and produces some Vit. K - NO DIGESTION OCCURS IN THE LARGE INTESTINE
  • 46. FECES! - 75% water - bacteria - mucus - undigested food - bile - bile pigments - cellulose (fiber)
  • 47. Nutrients  carbohydrates  lipids  proteins  vitamins  minerals  trace elements Adequate diet – provides sufficient energy and nutrients to support optimal growth and to maintain and repair body tissue
  • 48. Body Figure 15.34 Mass Index