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effects.Each year, more than 9.6 million adverse drug reactions occur in older Americans. Experts at the Food andDrug Administration (FDA) estimate that only 10% percent of adverse reactions are ever reported. As we agewe tend to process drugs at a slower rate. Our liver and detoxification mechanisms are easily compromised. FinanceThe risk of an adverse drug reaction is 33% percent higher in adults between ages 50 to 59 than it is infolks aged 40 to 49. Hotels FurnitureExperts reports that almost one- third of the drugs prescribed to the elderly arent needed and pose severehealth risks. This is especially true for the psychotropic drugs, known as benz odiaz epines (Xanax, Valium, GamesAtivan, Serax, Klonopin, etc.). Benz odiaz epines are central nervous system depressants that act on the Insuranceneurotransmitter GABA (gamma- amino butyric acid). GABA acts as a calming chemical as it transmits Carsmessages from one cell to another. Directly or indirectly, these drugs influence almost every brain function Moviesand most other bodily systems including the central nervous, neuromuscular, endocrine, andgastrointestinal systems. MapsBenz odiaz epines have numerous side effects, including poor sleep, seiz ures, mania, depression, suicide, Loanringing in the ears, amnesia, diz z iness, anxiety, disorientation, low blood pressure, nausea, fluid retention, Musicsexual dysfunction (decreased desire and performance), weakness, somnolence (prolonged drowsiness or Travela trance- like condition that may continue for a number of days), headaches and tardive dyskinesia. A mindboggling 40% of adults, 60 or older experience drug- induced tics or tardive dyskinesia (tremors oruncontrollable shakes) from taking a benz odiaz epine drug. Sadly, for many, these tremors are permanent.Over 61,000 older adults have developed Parkinsons disease from using antipsychotic drugs(benz odiaz epines and antidepressants).The crippling side effects and addictive nature of these drugs has been known for at least 40 years, yetdoctors continue prescribe them at an ever- increasing rate. Surveys show that over 5.6 million adults overthe age of 65 are now taking benz odiaz epines. A mouth dropping 50% of all women 60 and older will beprescribed a benz odiaz epine drug. And since addiction often occurs within 2 to 4 weeks of starting these PDFmyURL.com
drugs, the majority of folks are now dependant on these drugs. Tolerance to the hypnotic (sleep) effects ofthese drugs may occur within one week. Symptoms of tolerance are identical to drug withdrawal symptomsand may include anxiety, panic, severe insomnia, muscle pain and stiffness, depression, suicidal thoughts,rage, heart and lung problems, and agoraphobia (extreme fear of public or crowded spaces). Tragically,only 10 to 30% are able to successfully stop taking these drugs, most are addicted for life.How sad to live a productive, active life, only to become addicted to a life- draining, mind- numbing drug, allbecause you couldnt sleep or were a little agitated when the doctor visited the assisted living home theweek before. Seventy five percent of long- term- care residents receive psychotropic drugs. These drugs canseverely impair mental clarity, especially in the elderly. In a study in the state of Washington, in 46% of thepatients with drug- induced mental impairment, the problem was caused by minor tranquiliz ers or sleepingpills (benz odiaz epines, Ambien or Lunesta.); and in 11% , by antipsychotic drugs (antidepressants). Howmany of these folks are then erroneously diagnosed as having senile dementia, Alz heimers, or worse?Seniors taking benz odiaz epines and tricyclic antidepressant medications (Elavil, Traz adone, Doxepin,Tofranil, etc.) are involved in a conservative, 16,000 auto accidents each year. These same drugs causeover 32,000 seniors to fall and suffer hip fractures each year. And sadly, this contributes to the death of morethan 1,500 seniors each year. And even though they are promoted as being safer than older drugs, SSRIsarent without risk. Elderly patients taking Z oloft and other serotonin re- uptake inhibitor drugs (SSRIs), had80% percent more falls than those not on antidepressants.Sleeping pills (hypnotics) such as Ambien and Lunesta are not technically benz odiaz epines, but they actby the same mechanisms and have the same effects on the brain and body.Each year Americans consume 5 billion sleeping pills and sadly, 15,000 Americans die from taking sleepingpills.Excuse me, but has anyone ever heard of the over- the- counter supplement, melatonin? Melatonin is thesleep hormone! Studies show that declining levels of the sleep hormone melatonin is the cause of theirpoor- sleep. As we age our melatonin levels begin to drop. Older adults have one- third to one quarter theamount of melatonin as younger adults. PDFmyURL.com
Neurotransmitters and Essential NutrientsOur patients and the public at large should know that the neurotransmitters (brain chemicals) come from thevitamins, minerals and amino acids contained in our foods. A deficiency in any of these nutrients can causean assortment of health related illnesses, especially mood and sleep disorders. Inhibitory or relaxingneurotransmitters include serotonin and gamma- amino butyric acid (GABA). The neurotransmitter serotoninis produced from the amino acid 5- hydroxytryptophan (5HTP). GABA is mainly produced from the amino acidglutamine.GABA, 5HTP, and L- TheanineBoth GABA and 5HTP, have a calming effect on the brain. Benz odiaz epines work by increasing theeffectiveness of GABA. But, as weve learned these drugs have potentially lethal side effects. Instead ofusing a GABA additive loaded with potentially dangerous side effects, why not use an over- the- counterGABA or 5HTP supplement to reduce anxiety, stress, or help with sleep? Both work rather quickly, have fewside effects, and can be found at the local health food store. Usually only a small dose of GABA is needed,500- 1,000 mg. taken twice daily on an empty stomach. The brain doesnt readily absorb GABA, but anotheramino acid known as L- theanine, can boost GABA levels. I often recommend L- theanine, an amino acidfound in green tea. It has a calming effect on the brain. For anxiety related disorders the usual dose is 50-100mg taken on an empty stomach, two to three times daily.Research with human volunteers has demonstrated that L- theanine creates its relaxing effect inapproximately 30 to 40 minutes after ingestion. Supplementing with the supplement 5- hydroxytrryptophan(5HTP), a form of the amino acid tryptophan, helps raise serotonin levels. Studies show that 5HTP is aseffective in normaliz ing moods as antidepressant drugs. 5HTP also boosts melatonin levels by 200 percent.The recommended dose is 100mg three times a day.B- Vitamins and MoodSeveral studies have demonstrated the effectiveness of folic acid in reversing depression. One study PDFmyURL.com
showed that 92% of the folic acid group made a full recovery compared with only 70% of the control groupwho took the standard prescription drug therapy. Those who received the folic acid spent only 23 days inthe hospital while those on prescription therapy alone averaged 33 hospital days.Vitamin B- 1, also known as Thiamin, is important for proper cell function, especially nerve cells. It isinvolved in the production of acetylcholine. This nerve chemical is directly related to memory and physical,as well as mental energy. A deficiency of Vitamin B- 1 can lead to fatigue, mental confusion, emaciation,depression, irritability, upset stomach, nausea, and tingling in the extremities. Vitamin B- 1 has beenreported to be deficient in almost 50 percent of the elderly. Could this be one of the reasons pre- seniledementia and Alz heimers disease have increased so dramatically over the last few decades?Vitamin B12 helps form the myelin sheath that insulates nerve processes. This sheath allows rapidcommunication from one cell to another. A deficiency of B- 12 can cause a reduction in mental acuity,evidenced by poor memory. Could this be the cause of their Alz heimers or senile dementia? BothAlz heimers and senile dementia can be due to an overlooked deficiency of Vitamin B- 12. Calcium, which isdependant on adequate stomach acid, is necessary for normal absorption of B- 12. A Vitamin B- 12deficiency is usually caused by malabsorption and is mainly seen in elderly patients taking antacids or acidblocking drugs (Tagament, Prilosec, Tums, Nexium, Z antac, etc.). Because this deficiency is routinely seenin the elderly, I believe everyone over the age of 60 should be taking sublingual Vitamin B- 12.Isnt it time we start Saving Our Seniors from life- draining, mind- numbing drugs?By educating our patients and the public that the right nutrients add years to their lives and life to theiryears, we could help Stop the Overdosing of our Seniors on dangerous drugs they dont need.1. Wolfe s, et al. " Worst Pills Best Pills A Consumers Guide To Avoiding Drug- Induced Death or Illness,"Pocket Books New York, NY, 1999.2. Ray WA, Griffin MR, Shorr RI. Adverse drug reactions and the elderly. Health Affairs 1990; 9: 114 - 122.3. David N. Juurlink, M.D., Ph.D., et al., " The Risk of Suicide With Selective Serotonin Reuptake Inhibitors inthe Elderly," American Journal of Psychiatry, Vol. 163, No. 5, May 2006, pp. 813- 821. PDFmyURL.com
4. Vestal RE;, ed. Drug Treatment in the Elderly. Sydney, Australia: ADIS Health Science Press, 1984.5. Ray WA, Fought RL, Decker MD. Psychoactive drugs and the risk of injurious motor vehicle crashes inelderly drivers. American Journal of Epidemiology Oct 1, 1992; 136: 873 - 883.6. The estimate of 32,000 hip fractures in older adults is based on projecting the findings of this study ofdrug- induced hip fractures in older Michigan Medicaid patients to the entire country.7. Ray WA, Griffin MR, Schaffner W, Baugh DK, Melton LJ. Psychotropic drug use and the risk of hip fracture.New England Journal of Medicine Feb 12, 1987; 316: 363 - 369.8. Larson EB, Kukull WA, Buchner D, Reifler BV. Adverse drug reactions associated with global cognitiveimpairment in elderly persons. Annals of Internal Medicine Aug 1987; 107: 169 - 173.9. Fletcher SW, Colditz GA. Failure of estrogen plus progestin therapy for prevention. JAMA . 2002 Jul17;288(3):366- 8.10. Dealberto MJ, Seeman T, McAvay GJ, et al: Factors related to current and subsequent psychotropicdrug use in an elderly cohort. Journal of Clinical Epidemiology 50:357- 364,1997.11.Avorn J: Drug prescribing, drug taking, adverse reactions, and compliance in elderly patients, in ClinicalGeriatric Psychopharmacology. Edited by Salz man C. Baltimore, Williams & Wilkins, 1998.12. Murphree, R. " Treating and Beating Anxiety and Depression with Orthomolecular Medicine," Harrisonand Hampton Publishing, Birmingham, AL. 2006.13. Kelly, G.S. Folates: supplemental forms and therapeutic applications. Altern. Med. Rev. 1998 Jun; 3(3):208- 20.14. Carney, M.W. Neuropsychiatric disorders associated with nutritional deficiencies. Incidence andtherapeutic implications. CNS Drugs 1995; 3(4): 279- 90.15. Coppen, A., Bailey, J. Enhancement of the antidepressant action of fluoxetine by folic acid: arandomiz ed, placebo- controlled trial. J. Affect. Disorders 2000; 60: 121- 30.16. Yokogoshi H, Kobayashi M, Mochiz uki M, et al. Effect of theanine, r- glutamylethylamide, on brainmonoamines and striatal dopamine release in conscious rats. Neurochem Res. 1998 May;23(5):667- 73.17. Drs. PeterM. Brooks and Richard O. Day, New England Jour of Med, 1991;324(24): 1716- 25.18. Evans LK. " Sundown syndrome in institutional elederly." Jour of Am Geri Soc. 1987; 35:101- 8. PDFmyURL.com
About Dr. Murphree Dr. Murphree is a board certified nutritional specialist and chiropractic physician who has been in private practice since 1990. He is the founder and past clinic director for a large integrated medical practice located on the campus of Brookwood Hospital in Birmingham Alabama. The clinic was staffed with medical doctors, chiropractors, acupuncturists, nutritionists, and massage therapists. The clinic combined prescription and natural medicines for acute and chronic illnesses. He is the author of 5 books for patients and doctors, including " Treating and Beating Fibromyalgia and Chronic Fatigue Syndrome," " " Heart Disease What Your Doctor Wont Tell You" and " Treating and Beating Anxiety and Depression with Orthomolecular Medicine." His website is at http://www.treatingandbeating.com klo no p in and me lat o nin Inf o rmat io notalmda nipn lk e n oo We d ne s d ay,J une , 20 11 6 :0 0 PM Po s te d b y Sup e rb Site PDFmyURL.com
Despite making up only 14% percent of the U.S. population, those 65 and overconsume more than one third of all prescription drugs. Senior citiz ens take anaverage of 25 prescriptions a year. No one wants to go back to the days beforeantibiotics, insulin, and other life- saving drugs, but doesnt 25 prescriptions ayear seem excessive? CO PYRIG HT (C) 20 11 SUPERBSITE.INFO . ALL RIG HTS RESERVED. KLO NO PIN AND MELATO NIN | PRIVACY PDFmyURL.com