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Lesions of the Spinal Cord      Learning Module         Click to Begin
Main MenuOverview describes the module content & learning objectives  Please complete this section first!Contents houses t...
Overview   Introduction   Learning ObjectivesOverview Menu   Main Menu              Exit
Introduction •   This module reviews lesions of the spinal cord •   Module organization consists of three components. Over...
Learning Objectives    After completing this module you should be able to:    1. describe the signs and symptoms caused by...
ContentsRead these Instructions!Legend: symbols used throughout the moduleReview of the Spinal Cord (Under Construction)Le...
Instructions•   This module contains 9 interactive lesion lessons with animation.•   Lesson lessons begin with a question ...
Legend     Mechanism of injury        First-order neuron     Lesion                     Second-order neuron     Pain stimu...
R        L       Lesion of the right dorsal       column at L1 produces what       impairment?   Click for answer      Dam...
Right Dorsal Column LesionClick to animate                                                DRG                             ...
R         L    Lesion of the right fasciculus    cuneatus at C3 produces what    impairment?   Click for answer      Damag...
Right Fasciculus Cuneatus LesionClick to animate                                               DRG                        ...
R        L    Lesion of the right lateral    corticospinal tract at L1    produces what impairment?   Click for answer    ...
Right Lateral Corticospinal Tract Lesion                                                                     UMNClick to a...
R        L       Lesion of the right lateral       spinothalamic tract at L1       produces what impairment?   Click for a...
Right Lateral Spinothalamic Tract LesionClick to animate                                                                  ...
R       L     Lesion of the anterior gray and     white commissures (central     cord syndrome) at C5-C6     produces what...
Central Cord SyndromeClick to animate                                       C5-C6     DRG                                 ...
R        L     Complete transection of the right     half the spinal cord (Hemicord or     Brown-Sequard syndrome) at L1  ...
Hemicord Lesion (Brown-Sequard Syndrome)Click to animate                                             R                    ...
Hemicord Lesion (Brown-Sequard Syndrome)                                                                    UMNClick to an...
R       L     Complete transection of the     spinal cord (Transverse cord     lesion) at L1 would produce     what impair...
Transverse Cord LesionClick to animate                                             R                   L                  ...
Transverse Cord Lesion       UMN                      UMNClick to animate                                                 ...
R         L   Complete transection of the   dorsal columns, bilaterally,   (posterior cord syndrome) in   the cervical reg...
Posterior Cord SyndromeClick to animate                                                                       DRG         ...
Complete transection of the lateral                    R        Lcorticospinal and lateral spinothalamictracts with sparin...
Anterior Cord Syndrome                               UMN                                            UMNClick to animate   ...
Case-based PracticeRead these instructions!Patient Case #1Patient Case #2Patient Case #3   Main Menu                   Exit
Case Instructions• These patient cases are intended to facilitate the  integration and clinical application of information...
Review Questions: Case 1The patient complains of “clumsiness” of her left leg due to uncertainty of thelimb’s position in ...
Left Dorsal Column LesionClick to animate                                                             DRG                 ...
Review Questions: Case 2After a fall from his horse, the patient was alert and oriented but unable to moveanything but his...
Transverse Cord Lesion   UMN                       UMNClick to animate                                                    ...
Review Questions: Case 3Following surgical repair of a knife wound the patient is unable to stand or walk becausehe is una...
Hemicord Lesion (Brown-Sequard Syndrome)                                                                   UMNClick to ani...
The EndD. Michael McKeough, PT, EdD            © 2008
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Spinal cord lesions module

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Spinal cord lesions module

  1. 1. Lesions of the Spinal Cord Learning Module Click to Begin
  2. 2. Main MenuOverview describes the module content & learning objectives Please complete this section first!Contents houses the 9 interactive lesion lessons and directions for completing them.Patient Cases provides practice with feedback using patient cases. Exit
  3. 3. Overview Introduction Learning ObjectivesOverview Menu Main Menu Exit
  4. 4. Introduction • This module reviews lesions of the spinal cord • Module organization consists of three components. Overview consists of this Introduction and the Learning Objectives. Contents consists of Navigation Instructions, a Legend, and 9 interactive lesion lessons. Cases consists of Instructions and 3 interactive patient cases with feedback. • At the bottom of each page a navigation bar contains options to move throughout the module. • Material is presented at both the behavioral level and the neuroanatomical level. • The behavioral level is presented first and depicts a patient’s clinical presentation. • The neuroanatomical level depicts the detailed anatomy of first- order, second-order and third-order neurons. • The neuroanatomical level accounts for the patient’s behavioral presentation on examination under normal and lesioned conditions.Overview Menu Main Menu Exit
  5. 5. Learning Objectives After completing this module you should be able to: 1. describe the signs and symptoms caused by a lesion of the spinal cord (fasciculus gracilis and fasciculus cuneatus, lateral corticospinal tract, and lateral spinothalamic tract). 2. given a patient case (examination results and chief complaint), identify the functional systems causing the sensory and motor impairments. 3. correlate neurology information between the behavioral and neuroanatomical levels.Overview Menu Main Menu Exit
  6. 6. ContentsRead these Instructions!Legend: symbols used throughout the moduleReview of the Spinal Cord (Under Construction)Lesion lessons Dorsal column lesion Hemicord lesion Fasciculus cuneatus lesion Central cord syndrome Lateral corticospinal tract lesion Anterior cord syndrome Lateral spinothalamic tract lesion Posterior cord syndrome Transverse cord lesion Main Menu Exit
  7. 7. Instructions• This module contains 9 interactive lesion lessons with animation.• Lesson lessons begin with a question about the symptoms produced by that particular lesion.• Clicking the answer button will reveal the answer to the question.• Clicking the explanation button will lead to both behavioral and neuroanatomical explanations of the lesion.• Each presentation is launched by clicking the animation button. The same button serves to replay the animation if desired.• Any of the lessons may be accessed by simply clicking on the lesion title on the Contents page.• Please refer to the Legend that defines the symbols used throughout the module. Main Menu Content Menu Exit
  8. 8. Legend Mechanism of injury First-order neuron Lesion Second-order neuron Pain stimulus Third-order neuron Light touch stimulus Sensory impairment Function intact Function lostMain Menu Content Menu Exit
  9. 9. R L Lesion of the right dorsal column at L1 produces what impairment? Click for answer Damage to the right dorsal column at L1 causes the absence of light touch, vibration, and position sensation in the right leg. Only fasciculus gracilis exists below T6. Click for explanationMain Menu Content Menu Legend Exit
  10. 10. Right Dorsal Column LesionClick to animate DRG R L L1 Dorsal column lesion Ipsilateral loss of light touch,Common causes vibration, and position senseinclude MS, generalized below the lesion levelpenetrating injuries,and compression Below T6 only the fasciculus gracilisfrom tumors. is present.Main Menu Content Menu Legend Exit
  11. 11. R L Lesion of the right fasciculus cuneatus at C3 produces what impairment? Click for answer Damage to the right fasciculus cuneatus at C3 causes the absence of light touch, vibration, and position sensation in the right arm and upper trunk. Click for explanationMain Menu Content Menu Legend Exit
  12. 12. Right Fasciculus Cuneatus LesionClick to animate DRG R L C3 Fasciculus cuneatus lesion Ipsilateral loss of light touch,Common causes vibration, and position senseinclude MS, In the right arm and upper trunkpenetrating injuries,and compressionfrom tumors.Main Menu Content Menu Legend Exit
  13. 13. R L Lesion of the right lateral corticospinal tract at L1 produces what impairment? Click for answer Damage to the right lateral corticospinal tract at L1 causes upper motor neurons signs (weakness or paralysis, hyperreflexia, and hypertonia) in the right leg. Click for explanationMain Menu Content Menu Legend Exit
  14. 14. Right Lateral Corticospinal Tract Lesion UMNClick to animate R L L1 Lateral corticospinal tract lesionCommon causes Ipsilateral upper motor neurons signsinclude penetrating generalized below the lesion levelinjuries, lateral UMN signscompression from Weakness (Spastic paralysis)tumors, and MS. Hyperreflexia (+ Babinski, clonus) HypertoniaMain Menu Content Menu Legend Exit
  15. 15. R L Lesion of the right lateral spinothalamic tract at L1 produces what impairment? Click for answer Damage to the right lateral spinothalamic tract at L1 causes the absence of pain and temperature sensation in the left leg. Click for explanationMain Menu Content Menu Legend Exit
  16. 16. Right Lateral Spinothalamic Tract LesionClick to animate DRG R L L1 Lateral spinothalamic tract lesionCommon causes Contralateral loss of paininclude MS, and temperature sensepenetrating injuries, and compressionfrom tumors.Main Menu Content Menu Legend Exit
  17. 17. R L Lesion of the anterior gray and white commissures (central cord syndrome) at C5-C6 produces what impairment? Click for answer Damage to the anterior gray and white commissures at C5-C6 causes the absence of pain and temperature sensation in the C5 and C6 dermatomes in both upper extremities. Click for explanationMain Menu Content Menu Legend Exit
  18. 18. Central Cord SyndromeClick to animate C5-C6 DRG R L DRG Lateral Spinothalamic TractCommon causesinclude posttraumatic Impaired pain and temperaturecontusion and sensation, C5-C6 dermatomes,syringomyelia, and bilaterallyintrinsic spinal cordtumors.Main Menu Content Menu Legend Exit
  19. 19. R L Complete transection of the right half the spinal cord (Hemicord or Brown-Sequard syndrome) at L1 produces what impairments? Click for answer Damage to the right dorsal columns at L1 causes the absence of light touch, vibration, and position sense in the right leg. Damage to the lateral corticospinal tract causes upper motor neuron signs in the right leg (Monoplegia), and damage to the lateral spinothalamic tract causes the absence of pain and temperature sensation in the left leg. Click for explanationMain Menu Content Menu Legend Exit
  20. 20. Hemicord Lesion (Brown-Sequard Syndrome)Click to animate R L L1 Hemicord lesionCommon causes Dorsal column lesioninclude penetrating Ipsilateral loss of light touch,injuries, lateral vibration, and position sensecompression fromtumors, and MS. Lateral corticospinal tract lesion Ipsilateral upper motor neurons signsBuild the lesion Lateral spinothalamic tract lesion Contralateral loss of pain and temperature senseMain Menu Content Menu Legend Exit
  21. 21. Hemicord Lesion (Brown-Sequard Syndrome) UMNClick to animate DRG DRG R L L1 Dorsal column lesion Ipsilateral loss of light touch, vibration, and position sense Lateral corticospinal tract lesion Ipsilateral upper motor neurons signs Lateral spinothalamic tract lesion Contralateral loss of pain and temperature sense Hemicord lesionMain Menu Content Menu Legend Exit
  22. 22. R L Complete transection of the spinal cord (Transverse cord lesion) at L1 would produce what impairments? Click for answer Damage to the dorsal columns, bilaterally, causes the absence of light touch, vibration, and position sense in the both legs. Damage to the lateral corticospinal tracts, bilaterally, cause upper motor neuron signs in the both legs (Paraplegia), and damage to the lateral spinothalamic tracts, bilaterally, cause the absence of pain and temperature sensation in the both legs. Click for explanationMain Menu Content Menu Legend Exit
  23. 23. Transverse Cord LesionClick to animate R L Transverse cord lesionCommon causes Dorsal column lesioninclude trauma, Bilateral loss of light touch,tumors, transverse vibration, and position sensemyelitis, and MS. Lateral corticospinal tract lesion Bilateral upper motor neurons signsBuild the lesion Lateral spinothalamic tract lesion Bilateral loss of pain and temperature senseMain Menu Content Menu Legend Exit
  24. 24. Transverse Cord Lesion UMN UMNClick to animate DRG DRG R L Dorsal column lesion Ipsilateral loss of light touch, vibration, and position sense Lateral corticospinal tract lesion Ipsilateral upper motor neurons signs Lateral spinothalamic tract lesion Contralateral loss of pain and temperature sense Transverse cord lesionMain Menu Content Menu Legend Exit
  25. 25. R L Complete transection of the dorsal columns, bilaterally, (posterior cord syndrome) in the cervical region would produce what impairments? Click for answer Damage to the dorsal columns (fasciculus gracilis and cuneatus), bilaterally, causes the absence of light touch, vibration, and position sense, bilaterally, from the neck down (below the lesion level). Click for explanationMain Menu Content Menu Legend Exit
  26. 26. Posterior Cord SyndromeClick to animate DRG DRG R LCommon causes Dorsal column lesion (bilateral)include trauma, Bilateral loss of light touch,compression from vibration, and position sense,posteriorly located generalized below lesion leveltumors, and MS.Main Menu Content Menu Legend Exit
  27. 27. Complete transection of the lateral R Lcorticospinal and lateral spinothalamictracts with sparing of the dorsalcolumns, bilaterally, (anterior cordsyndrome) in the cervical region wouldproduce what impairments? Click for answer Damage to the lateral corticospinal tracts cause upper motor neuron signs, bilaterally, below the lesion level. Damage to lower motor neurons in the ventral horns cause lower motor neuron signs, bilaterally, at the lesion level. Damage to the lateral spinothalamic tracts cause absence of pain and temperature sensation, bilaterally, below the lesion level. Sparing of the dorsal columns leaves light touch, vibration, and position sense intact throughout. Click for explanationMain Menu Content Menu Legend Exit
  28. 28. Anterior Cord Syndrome UMN UMNClick to animate DRG DRG R L Anterior cord lesionCommon causes Lateral corticospinal tract lesioninclude anterior Ipsilateral upper motor neurons signsspinal arteryinfarct, trauma, Lateral spinothalamic tract lesionand MS. Contralateral loss of pain and temperature senseMain Menu Content Menu Legend Exit
  29. 29. Case-based PracticeRead these instructions!Patient Case #1Patient Case #2Patient Case #3 Main Menu Exit
  30. 30. Case Instructions• These patient cases are intended to facilitate the integration and clinical application of information about lesions of the spinal cord by coupling the findings on examination and patient interview with their neuroanatomical correlates.• Cases are presented from two perspectives. What lesion would account for a given set of examination results and patient history? For a given lesion, what signs and symptoms would be expected on examination?• Click on a Case number to begin the exercise. Main Menu Case Menu Exit
  31. 31. Review Questions: Case 1The patient complains of “clumsiness” of her left leg due to uncertainty of thelimb’s position in space. Active and passive ROM and strength are withinnormal limits (WNL) throughout. Light touch, two-point discrimination,proprioception, and vibration sense are intact in the right lower extremity butabsent in all dermatomes below the umbilicus in the left lower extremity. Sheis able to distinguish sharp from dull WNL in lower extremities, bilaterally.Damage to what system(s) is causing this patient’s problems? AnswerLesion of the left dorsal column (fasciculus gracilis) at approximately T10.Lateral corticospinal tracts are intact, bilaterally: AROM and strength are WNLLateral spinothalamic tracts are intact, bilaterally: sharp/ dull is WNLDorsal column is intact on the right: light touch, two-point discrimination, proprioception, and vibration are WNLDorsal column is absent on the left: light touch, two-point discrimination, proprioception (limb position in space), and vibration are absent in all dermatomes below the umbilicusLesion level, T10: the umbilicus is located in the T10 dermatome Main Menu Case Menu Exit Show lesion
  32. 32. Left Dorsal Column LesionClick to animate DRG R L T10 Dorsal column lesion Ipsilateral loss of light touch, vibration, and position sense Main Menu Case Menu Exit
  33. 33. Review Questions: Case 2After a fall from his horse, the patient was alert and oriented but unable to moveanything but his head. He was unable to sense light touch or pain from the neckdown. He could turn his head but shoulder shrug was weak. Speech wasnormal but respiration was labored and required a respirator.Damage to what system(s) is causing this patient’s problems? AnswerComplete transection of the spinal cord (transverse lesion ) at approximately C3(Tetroplegia, Christopher Reeve)Lateral corticospinal tracts absent, bilaterally, below C3: unable to move anybody part except head and shoulder shrug (C3-5)Dorsal columns absent , bilaterally, below C3: unable to sense light touch belowneckLateral spinothalamic tracts absent, bilaterally, below C3: unable to sense painbelow neckLesion level, C3: patient was alert and oriented (cortex and reticular activatingsystem intact), he could turn his head (spinal accessory nerve), shoulder shrugand respiration were weak (shoulder elevator and respiratory muscles C3-5) Main Menu Case Menu Exit Show lesion
  34. 34. Transverse Cord Lesion UMN UMNClick to animate DRG DRG R L C3 Dorsal column lesion Ipsilateral loss of light touch, vibration, and position sense Lateral corticospinal tract lesion Ipsilateral upper motor neurons signs Lateral spinothalamic tract lesion Contralateral loss of pain and temperature sense Transverse cord lesion Main Menu Case Menu Exit
  35. 35. Review Questions: Case 3Following surgical repair of a knife wound the patient is unable to stand or walk becausehe is unable to move or bear weight on his right leg. Light touch, position and vibrationsense are WNL in the left lower extremity but absent in the right below the crest of theilium. Active range of motion and strength are normal in the left lower extremity butabsent in the right (hip, knee, and ankle). Pain and temperature sensation are intact inthe right lower extremity but absent in the left below T12.Damage to what system(s) is causing this patient’s problems? AnswerHemisection of the spinal cord on the right at approximately L1Dorsal column is intact on the left but absent on the right: light touch, positionand vibration sense are WNL in the left lower extremity but absent in the rightLateral corticospinal tract is intact on the left but absent on the right: activerange of motion and strength are normal in the left lower extremity but absent inthe rightLateral spinothalamic tract is intact on the left but absent on the right: pain andtemperature sensation are intact in the right lower extremity but absent in the leftLesion level, approximately L1: hip flexion absent on right (L2), pain andtemperature sense absent below T12 Main Menu Case Menu Exit Show lesion
  36. 36. Hemicord Lesion (Brown-Sequard Syndrome) UMNClick to animate DRG DRG R L T12 Dorsal column lesion Ipsilateral loss of light touch, vibration, and position sense Lateral corticospinal tract lesion Ipsilateral upper motor neurons signs Lateral spinothalamic tract lesion Contralateral loss of pain and temperature sense Hemicord lesion Main Menu Case Menu Exit
  37. 37. The EndD. Michael McKeough, PT, EdD © 2008
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