This document provides an overview of carcinoma of the thyroid gland, including epidemiology, causes and risk factors, classification, clinical presentation, diagnosis, and management. Some key points include: - Papillary carcinoma is the most common type, accounting for around 80% of cases. - Risk factors include radiation exposure, family history, and chronic iodine deficiency. - Clinical presentation varies depending on the type but commonly includes a neck mass or lymph node enlargement. - Diagnosis involves laboratory tests, imaging like ultrasound, and fine needle aspiration biopsy. - Treatment options include surgery, radioactive iodine therapy, chemotherapy, and radiation therapy. Surgical management depends on factors like tumor size and

1. CARCINOMA OF THYROID GLAND Dr - Ahmed Mirza Al-Shammasi 2031040009 Surgical Intern – KFU – Saudi Arabia

10. Thyroid Neoplasm Benign Malignant Secondary Primary Follicular Papillary Follicular Cells Parafollicular Cells Lymphoid Cells Lymphoma Medullary Differentiated Undifferentiated Anaplastic Follicular Papillary Hurthle Cell

45. PROGNOSIS Tumor Prognosis Papillary Ca. 74-93% long-term survival rate Follicular Ca. 43-94% long-term survival rate Hurthle Cell Ca. 20% mortality rate at 10 years Medullary Ca. 80% 10-year survival rate 45% with LN involvement Anaplastic Tumor Median survival of 4 to 5 months at time of diagnosis

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