SlideShare a Scribd company logo
1 of 34
DENGUE
Key point: Early
recognition and
timely intervention
Airamsherlyn P. Natinga, M.D.
DISCUSSION
Epidemiology
 estimated 50 million dengue infections occur
annually
 approximately 2.5 billion people live in dengue
endemic countries
Epidemiology
 From 1993 to 2007, a total of 307,850
cases of dengue with 3,406 deaths were
reported in the Philippines.
 Most of the cases occur in children
between 1 to 10 years old with a case
fatality rate of 1.7%.
“Dengue is one disease entity with
different clinical presentations and
often with unpredictable clinical
evolution and outcome.”
Expert consensus groups
Case Classification
Expert group (Geneva,
Switzerland, 2008)
Criteria for Dengue ± Warning
Signs
Herman’s Rash
Dengue with
warning signs
Severe dengue
Transmission
Dengue virus (DEN)
 small single-stranded RNA virus comprising
four distinct serotypes (DEN-1 to -4)
 genus Flavivirus, family Flaviviridae
 Asian genotypes of DEN-2 and DEN-3 are
frequently associated with severe disease
accompanying secondary dengue
infections
Dengue virus (DEN)
Vector: Aedes aegypti
 immature stages are found in water-filled
habitats, mostly in artificial containers
closely associated with human dwellings
and often indoors.
Host
 After an incubation period of 4-10 days, infection
by any of the four virus serotypes can produce a
wide spectrum of illness, although most infections
are asymptomatic or subclinical
Individual Risk factors
 Age
 Ethnicity
 Chronic illnesses
Blood meal
viremia
Immune
response
Genetic
Virus
Severe dengue
Plasma leakage
Transient and reversible imbalance of
inflammatory mediators, cytokines and
chemokines
Endothelial cell dysfunction
Derangement of hemocoagulation system
Shock Bleeding
Course of dengue
illness
Clinical problems
Management
Group A
 able to tolerate adequate volumes of oral
fluids and pass urine at least once every six
hours, and do not have any of the warning
signs, particularly when fever subsides.
 Sent home
Group B
 Referred for in-hospital management
Group C
 Emergency treatment and urgent referral
Prevention
 Vector control
- controlling larval habitats and
combatting adult mosquitos by
screening widows and doors and using
household insecticide space sprays.
 Provision of reliable potable water.
 Sanitation
 Solid waste management
 Health education
 COMMUNITY PARTICIPATION
New Avenues
 Tetravalent dengue vaccines are under
development.
Dengue Hemorrhagic Fever

More Related Content

What's hot (20)

Multiple Myeloma
Multiple MyelomaMultiple Myeloma
Multiple Myeloma
 
Acute pancreatitis investigations and treatment
Acute pancreatitis investigations and treatmentAcute pancreatitis investigations and treatment
Acute pancreatitis investigations and treatment
 
Aplastic anemia
Aplastic anemiaAplastic anemia
Aplastic anemia
 
Hemophilia by Suhasis Mondal
Hemophilia by Suhasis MondalHemophilia by Suhasis Mondal
Hemophilia by Suhasis Mondal
 
Rabies
RabiesRabies
Rabies
 
Dengue fever
Dengue feverDengue fever
Dengue fever
 
Don't Neglect the NTDs!
Don't Neglect the NTDs!Don't Neglect the NTDs!
Don't Neglect the NTDs!
 
Diagnosis sickle cell anemia
Diagnosis sickle cell anemiaDiagnosis sickle cell anemia
Diagnosis sickle cell anemia
 
Multiple myeloma
Multiple myelomaMultiple myeloma
Multiple myeloma
 
10. 1 disorders of retina
10. 1 disorders of retina10. 1 disorders of retina
10. 1 disorders of retina
 
hepatitis b and d
hepatitis b and dhepatitis b and d
hepatitis b and d
 
Management of Hepatitis B
Management of Hepatitis BManagement of Hepatitis B
Management of Hepatitis B
 
Arboviral diseases prevalence in India
Arboviral diseases prevalence in IndiaArboviral diseases prevalence in India
Arboviral diseases prevalence in India
 
Approach To A Patient With Anemia
Approach To A Patient With Anemia  Approach To A Patient With Anemia
Approach To A Patient With Anemia
 
Hepatitis E infection
Hepatitis E infectionHepatitis E infection
Hepatitis E infection
 
Rabies
RabiesRabies
Rabies
 
Pancytopenia
PancytopeniaPancytopenia
Pancytopenia
 
Dengue fever presentation
Dengue fever presentationDengue fever presentation
Dengue fever presentation
 
Graft versus host disease
Graft versus host diseaseGraft versus host disease
Graft versus host disease
 
APPROACH TO PANCYTOPENIA
APPROACH TO PANCYTOPENIA APPROACH TO PANCYTOPENIA
APPROACH TO PANCYTOPENIA
 

Viewers also liked (20)

Dengue and Dengue Hemorrhagic Fever
Dengue and Dengue Hemorrhagic Fever Dengue and Dengue Hemorrhagic Fever
Dengue and Dengue Hemorrhagic Fever
 
Dengue Fever Power Point
Dengue Fever Power PointDengue Fever Power Point
Dengue Fever Power Point
 
Dengue
DengueDengue
Dengue
 
Dengue hemorrhagic fever (dhf)
Dengue hemorrhagic fever (dhf)Dengue hemorrhagic fever (dhf)
Dengue hemorrhagic fever (dhf)
 
DENGUE FEVER
DENGUE FEVERDENGUE FEVER
DENGUE FEVER
 
Dengue ppt
Dengue pptDengue ppt
Dengue ppt
 
Dengue fever presentation
Dengue fever presentationDengue fever presentation
Dengue fever presentation
 
Dengue fever slide
Dengue fever slideDengue fever slide
Dengue fever slide
 
DENGUE HEMORRHAGIC FEVER
DENGUE HEMORRHAGIC FEVERDENGUE HEMORRHAGIC FEVER
DENGUE HEMORRHAGIC FEVER
 
Viral Haemorrhagic Fevers with special reference to Dengue
Viral Haemorrhagic Fevers with special reference to DengueViral Haemorrhagic Fevers with special reference to Dengue
Viral Haemorrhagic Fevers with special reference to Dengue
 
Dengue fever
Dengue feverDengue fever
Dengue fever
 
Lecture 15. hemorrhagic fevers
Lecture 15. hemorrhagic feversLecture 15. hemorrhagic fevers
Lecture 15. hemorrhagic fevers
 
Dengue Hemorrhagic Fever- Case Study
Dengue Hemorrhagic Fever- Case StudyDengue Hemorrhagic Fever- Case Study
Dengue Hemorrhagic Fever- Case Study
 
Viral Haemorrhagic Fevers
Viral Haemorrhagic FeversViral Haemorrhagic Fevers
Viral Haemorrhagic Fevers
 
Dengue virus
Dengue virus  Dengue virus
Dengue virus
 
Dengue fever ppt(1)
Dengue fever ppt(1)Dengue fever ppt(1)
Dengue fever ppt(1)
 
Dengue ppt
Dengue pptDengue ppt
Dengue ppt
 
Malaria
MalariaMalaria
Malaria
 
Malaria powerpoint
Malaria powerpointMalaria powerpoint
Malaria powerpoint
 
Dengue hemorrhagic fever
Dengue hemorrhagic feverDengue hemorrhagic fever
Dengue hemorrhagic fever
 

Similar to Dengue Hemorrhagic Fever

Dengue 1214446525598008-8
Dengue 1214446525598008-8Dengue 1214446525598008-8
Dengue 1214446525598008-8Chuan Yong
 
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...Arun Vasireddy
 
Dengue fever pravin yerpude
Dengue fever pravin yerpudeDengue fever pravin yerpude
Dengue fever pravin yerpudedrkeertijogdand
 
Adenovirus Microbiology
Adenovirus MicrobiologyAdenovirus Microbiology
Adenovirus Microbiologysantusan
 
Adenovirus epidemiology infection
Adenovirus epidemiology infectionAdenovirus epidemiology infection
Adenovirus epidemiology infectionMubashir Qureshi
 
Dengue fever final
Dengue fever finalDengue fever final
Dengue fever finalSaleem Rana
 
Dengue fever in children 2019 by Dr Kibogoyo
Dengue fever in children 2019 by Dr KibogoyoDengue fever in children 2019 by Dr Kibogoyo
Dengue fever in children 2019 by Dr KibogoyoGeorgeKibogoyo
 
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)Dr Padmesh Vadakepat
 
denguefever-170215174051 (1).pdf
denguefever-170215174051 (1).pdfdenguefever-170215174051 (1).pdf
denguefever-170215174051 (1).pdfkuhanKalaichelvan1
 
2. fever with rash
2. fever with rash2. fever with rash
2. fever with rashWhiteraven68
 
denguefever-160122140425.pdf.............
denguefever-160122140425.pdf.............denguefever-160122140425.pdf.............
denguefever-160122140425.pdf.............kallupalamsiyaf
 

Similar to Dengue Hemorrhagic Fever (20)

Dengue 1214446525598008-8
Dengue 1214446525598008-8Dengue 1214446525598008-8
Dengue 1214446525598008-8
 
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...
 
Dengue Fever
Dengue FeverDengue Fever
Dengue Fever
 
Dengue fever pravin yerpude
Dengue fever pravin yerpudeDengue fever pravin yerpude
Dengue fever pravin yerpude
 
Adenovirus Microbiology
Adenovirus MicrobiologyAdenovirus Microbiology
Adenovirus Microbiology
 
Dengue
DengueDengue
Dengue
 
Dengue fever
Dengue feverDengue fever
Dengue fever
 
Adenovirus epidemiology infection
Adenovirus epidemiology infectionAdenovirus epidemiology infection
Adenovirus epidemiology infection
 
Dengue fever final
Dengue fever finalDengue fever final
Dengue fever final
 
DENGUE.pptx
DENGUE.pptxDENGUE.pptx
DENGUE.pptx
 
Reaction Paper On Dengue
Reaction Paper On DengueReaction Paper On Dengue
Reaction Paper On Dengue
 
Dengue fever in children 2019 by Dr Kibogoyo
Dengue fever in children 2019 by Dr KibogoyoDengue fever in children 2019 by Dr Kibogoyo
Dengue fever in children 2019 by Dr Kibogoyo
 
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)
 
denguefever-170215174051 (1).pdf
denguefever-170215174051 (1).pdfdenguefever-170215174051 (1).pdf
denguefever-170215174051 (1).pdf
 
Dengue fever
Dengue feverDengue fever
Dengue fever
 
DENGUE FEVER.pptx
DENGUE FEVER.pptxDENGUE FEVER.pptx
DENGUE FEVER.pptx
 
Dengue
DengueDengue
Dengue
 
2. fever with rash
2. fever with rash2. fever with rash
2. fever with rash
 
denguefever-160122140425.pdf.............
denguefever-160122140425.pdf.............denguefever-160122140425.pdf.............
denguefever-160122140425.pdf.............
 
Dengue
DengueDengue
Dengue
 

Recently uploaded

Pharmacology of drugs acting on Renal System.pdf
Pharmacology of drugs acting on Renal System.pdfPharmacology of drugs acting on Renal System.pdf
Pharmacology of drugs acting on Renal System.pdfAFFIFA HUSSAIN
 
Multiple sclerosis diet.230524.ppt3.pptx
Multiple sclerosis diet.230524.ppt3.pptxMultiple sclerosis diet.230524.ppt3.pptx
Multiple sclerosis diet.230524.ppt3.pptxMeenakshiGursamy
 
Antiplatelets in IHD, Dose Duration, DAPT vs SAPT
Antiplatelets in IHD, Dose Duration, DAPT vs SAPTAntiplatelets in IHD, Dose Duration, DAPT vs SAPT
Antiplatelets in IHD, Dose Duration, DAPT vs SAPTAkashGanganePatil1
 
Effects of vaping e-cigarettes on arterial health
Effects of vaping e-cigarettes on arterial healthEffects of vaping e-cigarettes on arterial health
Effects of vaping e-cigarettes on arterial healthCatherine Liao
 
Renal Replacement Therapy in Acute Kidney Injury -time modality -Dr Ayman Se...
Renal Replacement Therapy in Acute Kidney Injury -time  modality -Dr Ayman Se...Renal Replacement Therapy in Acute Kidney Injury -time  modality -Dr Ayman Se...
Renal Replacement Therapy in Acute Kidney Injury -time modality -Dr Ayman Se...Ayman Seddik
 
Circulation through Special Regions -characteristics and regulation
Circulation through Special Regions -characteristics and regulationCirculation through Special Regions -characteristics and regulation
Circulation through Special Regions -characteristics and regulationMedicoseAcademics
 
Cardiovascular Physiology - Regulation of Cardiac Pumping
Cardiovascular Physiology - Regulation of Cardiac PumpingCardiovascular Physiology - Regulation of Cardiac Pumping
Cardiovascular Physiology - Regulation of Cardiac PumpingMedicoseAcademics
 
Scientificity and feasibility study of non-invasive central arterial pressure...
Scientificity and feasibility study of non-invasive central arterial pressure...Scientificity and feasibility study of non-invasive central arterial pressure...
Scientificity and feasibility study of non-invasive central arterial pressure...Catherine Liao
 
Hemodialysis: Chapter 2, Extracorporeal Blood Circuit - Dr.Gawad
Hemodialysis: Chapter 2, Extracorporeal Blood Circuit - Dr.GawadHemodialysis: Chapter 2, Extracorporeal Blood Circuit - Dr.Gawad
Hemodialysis: Chapter 2, Extracorporeal Blood Circuit - Dr.GawadNephroTube - Dr.Gawad
 
CT scan of penetrating abdominopelvic trauma
CT scan of penetrating abdominopelvic traumaCT scan of penetrating abdominopelvic trauma
CT scan of penetrating abdominopelvic traumassuser144901
 
Cas 28578-16-7 PMK ethyl glycidate ( new PMK powder) best suppler
Cas 28578-16-7 PMK ethyl glycidate ( new PMK powder) best supplerCas 28578-16-7 PMK ethyl glycidate ( new PMK powder) best suppler
Cas 28578-16-7 PMK ethyl glycidate ( new PMK powder) best supplerSherrylee83
 
NCLEX RN REVIEW EXAM CONTENT BLUE BOOK PDF
NCLEX RN REVIEW EXAM CONTENT BLUE BOOK PDFNCLEX RN REVIEW EXAM CONTENT BLUE BOOK PDF
NCLEX RN REVIEW EXAM CONTENT BLUE BOOK PDFShahid Hussain
 
DIGITAL RADIOGRAPHY-SABBU KHATOON .pptx
DIGITAL RADIOGRAPHY-SABBU KHATOON  .pptxDIGITAL RADIOGRAPHY-SABBU KHATOON  .pptx
DIGITAL RADIOGRAPHY-SABBU KHATOON .pptxSabbu Khatoon
 
Tips and tricks to pass the cardiovascular station for PACES exam
Tips and tricks to pass the cardiovascular station for PACES examTips and tricks to pass the cardiovascular station for PACES exam
Tips and tricks to pass the cardiovascular station for PACES examJunhao Koh
 
PT MANAGEMENT OF URINARY INCONTINENCE.pptx
PT MANAGEMENT OF URINARY INCONTINENCE.pptxPT MANAGEMENT OF URINARY INCONTINENCE.pptx
PT MANAGEMENT OF URINARY INCONTINENCE.pptxdrtabassum4
 
Cervical screening – taking care of your health flipchart (Vietnamese)
Cervical screening – taking care of your health flipchart (Vietnamese)Cervical screening – taking care of your health flipchart (Vietnamese)
Cervical screening – taking care of your health flipchart (Vietnamese)Cancer Institute NSW
 
Retinal consideration in cataract surgery
Retinal consideration in cataract surgeryRetinal consideration in cataract surgery
Retinal consideration in cataract surgeryKafrELShiekh University
 
TEST BANK For Timby's Introductory Medical-Surgical Nursing, 13th Edition by ...
TEST BANK For Timby's Introductory Medical-Surgical Nursing, 13th Edition by ...TEST BANK For Timby's Introductory Medical-Surgical Nursing, 13th Edition by ...
TEST BANK For Timby's Introductory Medical-Surgical Nursing, 13th Edition by ...marcuskenyatta275
 
Creating Accessible Public Health Communications
Creating Accessible Public Health CommunicationsCreating Accessible Public Health Communications
Creating Accessible Public Health Communicationskatiequigley33
 
TEST BANK For Lewis's Medical Surgical Nursing in Canada, 4th Edition by Jane...
TEST BANK For Lewis's Medical Surgical Nursing in Canada, 4th Edition by Jane...TEST BANK For Lewis's Medical Surgical Nursing in Canada, 4th Edition by Jane...
TEST BANK For Lewis's Medical Surgical Nursing in Canada, 4th Edition by Jane...marcuskenyatta275
 

Recently uploaded (20)

Pharmacology of drugs acting on Renal System.pdf
Pharmacology of drugs acting on Renal System.pdfPharmacology of drugs acting on Renal System.pdf
Pharmacology of drugs acting on Renal System.pdf
 
Multiple sclerosis diet.230524.ppt3.pptx
Multiple sclerosis diet.230524.ppt3.pptxMultiple sclerosis diet.230524.ppt3.pptx
Multiple sclerosis diet.230524.ppt3.pptx
 
Antiplatelets in IHD, Dose Duration, DAPT vs SAPT
Antiplatelets in IHD, Dose Duration, DAPT vs SAPTAntiplatelets in IHD, Dose Duration, DAPT vs SAPT
Antiplatelets in IHD, Dose Duration, DAPT vs SAPT
 
Effects of vaping e-cigarettes on arterial health
Effects of vaping e-cigarettes on arterial healthEffects of vaping e-cigarettes on arterial health
Effects of vaping e-cigarettes on arterial health
 
Renal Replacement Therapy in Acute Kidney Injury -time modality -Dr Ayman Se...
Renal Replacement Therapy in Acute Kidney Injury -time  modality -Dr Ayman Se...Renal Replacement Therapy in Acute Kidney Injury -time  modality -Dr Ayman Se...
Renal Replacement Therapy in Acute Kidney Injury -time modality -Dr Ayman Se...
 
Circulation through Special Regions -characteristics and regulation
Circulation through Special Regions -characteristics and regulationCirculation through Special Regions -characteristics and regulation
Circulation through Special Regions -characteristics and regulation
 
Cardiovascular Physiology - Regulation of Cardiac Pumping
Cardiovascular Physiology - Regulation of Cardiac PumpingCardiovascular Physiology - Regulation of Cardiac Pumping
Cardiovascular Physiology - Regulation of Cardiac Pumping
 
Scientificity and feasibility study of non-invasive central arterial pressure...
Scientificity and feasibility study of non-invasive central arterial pressure...Scientificity and feasibility study of non-invasive central arterial pressure...
Scientificity and feasibility study of non-invasive central arterial pressure...
 
Hemodialysis: Chapter 2, Extracorporeal Blood Circuit - Dr.Gawad
Hemodialysis: Chapter 2, Extracorporeal Blood Circuit - Dr.GawadHemodialysis: Chapter 2, Extracorporeal Blood Circuit - Dr.Gawad
Hemodialysis: Chapter 2, Extracorporeal Blood Circuit - Dr.Gawad
 
CT scan of penetrating abdominopelvic trauma
CT scan of penetrating abdominopelvic traumaCT scan of penetrating abdominopelvic trauma
CT scan of penetrating abdominopelvic trauma
 
Cas 28578-16-7 PMK ethyl glycidate ( new PMK powder) best suppler
Cas 28578-16-7 PMK ethyl glycidate ( new PMK powder) best supplerCas 28578-16-7 PMK ethyl glycidate ( new PMK powder) best suppler
Cas 28578-16-7 PMK ethyl glycidate ( new PMK powder) best suppler
 
NCLEX RN REVIEW EXAM CONTENT BLUE BOOK PDF
NCLEX RN REVIEW EXAM CONTENT BLUE BOOK PDFNCLEX RN REVIEW EXAM CONTENT BLUE BOOK PDF
NCLEX RN REVIEW EXAM CONTENT BLUE BOOK PDF
 
DIGITAL RADIOGRAPHY-SABBU KHATOON .pptx
DIGITAL RADIOGRAPHY-SABBU KHATOON  .pptxDIGITAL RADIOGRAPHY-SABBU KHATOON  .pptx
DIGITAL RADIOGRAPHY-SABBU KHATOON .pptx
 
Tips and tricks to pass the cardiovascular station for PACES exam
Tips and tricks to pass the cardiovascular station for PACES examTips and tricks to pass the cardiovascular station for PACES exam
Tips and tricks to pass the cardiovascular station for PACES exam
 
PT MANAGEMENT OF URINARY INCONTINENCE.pptx
PT MANAGEMENT OF URINARY INCONTINENCE.pptxPT MANAGEMENT OF URINARY INCONTINENCE.pptx
PT MANAGEMENT OF URINARY INCONTINENCE.pptx
 
Cervical screening – taking care of your health flipchart (Vietnamese)
Cervical screening – taking care of your health flipchart (Vietnamese)Cervical screening – taking care of your health flipchart (Vietnamese)
Cervical screening – taking care of your health flipchart (Vietnamese)
 
Retinal consideration in cataract surgery
Retinal consideration in cataract surgeryRetinal consideration in cataract surgery
Retinal consideration in cataract surgery
 
TEST BANK For Timby's Introductory Medical-Surgical Nursing, 13th Edition by ...
TEST BANK For Timby's Introductory Medical-Surgical Nursing, 13th Edition by ...TEST BANK For Timby's Introductory Medical-Surgical Nursing, 13th Edition by ...
TEST BANK For Timby's Introductory Medical-Surgical Nursing, 13th Edition by ...
 
Creating Accessible Public Health Communications
Creating Accessible Public Health CommunicationsCreating Accessible Public Health Communications
Creating Accessible Public Health Communications
 
TEST BANK For Lewis's Medical Surgical Nursing in Canada, 4th Edition by Jane...
TEST BANK For Lewis's Medical Surgical Nursing in Canada, 4th Edition by Jane...TEST BANK For Lewis's Medical Surgical Nursing in Canada, 4th Edition by Jane...
TEST BANK For Lewis's Medical Surgical Nursing in Canada, 4th Edition by Jane...
 

Dengue Hemorrhagic Fever