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Map Zebrafish Short Fin Mutant With 5 Markers

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adhikaribrothers

1. (10 pts) You set up a mapping experiment to map the Zebrafish short fin mutant was discovered in the sjD inbred strain, so you crossed a homozygous short fin to a WT sjC strain to obtain heterozygous F1 progeny. You then inter-crossed the F1 s (F1F1) and picked out the 20 short fin fish from the F2 progeny. Map the mutant with respect to the 5 markers below. The order of the 5 markers is known: M1-M2-M3-M4-M5. Individual fish are marked by a number across the top. C=sj C chromosomal marker, D=sjD chromosomal marker. a) How many recombination events occurred between the short fin mutation and each marker? How far is short fin from each marker (in cM)? M1: M2: M3: M4: MS: b) On the drawing of chromosome 7 below (with the order of the markers shown), indicate approximately where the short fin mutation is located:.

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1. (10 pts) You set up a mapping experiment to map the Zebrafish short fin mutant was discovered in the sjD inbred strain, so you crossed a homozygous short fin to a WT sjC strain to obtain heterozygous F1 progeny. You then inter-crossed the F1 s (F1F1) and picked out the 20 short fin fish from the F2 progeny. Map the mutant with respect to the 5 markers below. The order of the 5 markers is known: M1-M2-M3-M4-M5. Individual fish are marked by a number across the top. C=sj C chromosomal marker, D=sjD chromosomal marker. a) How many recombination events occurred between the short fin mutation and each marker? How far is short fin from each marker (in cM)? M1: M2: M3: M4: MS: b) On the drawing of chromosome 7 below (with the order of the markers shown), indicate approximately where the short fin mutation is located:

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Map Zebrafish Short Fin Mutant With 5 Markers

  • 1. 1. (10 pts) You set up a mapping experiment to map the Zebrafish short fin mutant was discovered in the sjD inbred strain, so you crossed a homozygous short fin to a WT sjC strain to obtain heterozygous F1 progeny. You then inter-crossed the F1 s (F1F1) and picked out the 20 short fin fish from the F2 progeny. Map the mutant with respect to the 5 markers below. The order of the 5 markers is known: M1-M2-M3-M4-M5. Individual fish are marked by a number across the top. C=sj C chromosomal marker, D=sjD chromosomal marker. a) How many recombination events occurred between the short fin mutation and each marker? How far is short fin from each marker (in cM)? M1: M2: M3: M4: MS: b) On the drawing of chromosome 7 below (with the order of the markers shown), indicate approximately where the short fin mutation is located: