2. SEER STATISTICS
๏ Brain tumors account for 1.4% of all cancers
๏ Median age of diagnosis is 58 years.
๏ Incidence is 6.4 per 100,000 men and
women per year
๏ The 5-year survival for localized brain and
other nervous system cancer is 36.3%.
๏ Brain tumors account for 2.6% of all cancer
deaths
3. INTRODUCTION
๏ Sixty percent of all primary brain tumours are
glial tumours, and two-thirds of these are
clinically aggressive, high-grade tumours.
15. CONVENTIONAL PLANNING
๏ Disadvantages
๏ Irradiation of large volumes of brain with
normal tissue also
๏ Higher toxicity and side effects
๏ Lack of 3D visualization of tumor
๏ 2D planning of 3D tumor
18. TAKING PLANNING CT SLICES IN
NEUROONCOLOGY
๏ถ Different from diagnostic imaging
๏ถ Use appropriate immobilization device
๏ถ Image the patient in treatment position
27. ๏ โStereoโ: Greek: Solid or 3 dimensional โtactโ Latin: To
touch: Greek โtaxicโ an arrangement
๏ Stereotactic: 3 dimensional arrangement to touch
๏ Stereotactic Radiosurgery (SRS): Stereotactically
directed conformal radiation in a single fraction
๏ Stereotactic Radiation Therapy (SRT): Stereotactically
directed conformal radiation in multiple fractions
๏ Fractionated Stereotactic Radiosurgery (FSR):
Stereotactically directed conformal radiation in 2-5
fractions
28. ๏ Advantages of SRS and SRT over 3DCRT
High conformity
To treat small lesions not amenable to 3D
CRT
Higher tumor dose
Save larger amount of normal tissue
34. ADVANTAGES
โข Over 30 years of clinical use and a large clinical
experience
โข Very high targeting precision
โข Multiple targets treated during a single treatment
session
DISADVANTAGES
โข Use in the brain only
โข Painful stereotactic head frame
โข Difficult to treat lesions located in the periphery of the
brain
โข Co sources decay, increasing treatment time and cost
to replace after 5 years
36. ADVANTAGES
โข More commonplace technology in hospitals
โข No invasive stereotactic frame
โข Can be used for extracranial tumors also
DISADVANTAGES
โข Painful head frame
โข Less targeting accuracy and treatment accuracy when treating
extracranial tumors
50. SUMMARY
๏ Multiple options and techniques available for
treating brain tumors.
๏ Need to use the optimum technique
๏ Decision to be based on need of patient and
available technique.